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List of works by Claus Oxvig

A characteristic signature of insulin-like growth factor (IGF) axis expression during osteogenic differentiation of human dental pulp cells (hDPCs): Potential co-ordinated regulation of IGF action

scientific article published on 26 July 2018

A common variant of the pregnancy-associated plasma protein-A (PAPPA) gene encodes a protein with reduced proteolytic activity towards IGF-binding proteins

scientific article published on 13 September 2019

A novel neutralizing antibody targeting pregnancy-associated plasma protein-a inhibits ovarian cancer growth and ascites accumulation in patient mouse tumorgrafts

scientific article

An isolated, surface-expressed I domain of the integrin alphaLbeta2 is sufficient for strong adhesive function when locked in the open conformation with a disulfide bond.

scholarly article

Anthropometric and biochemical correlates of PAPP-A2, free IGF-I, and IGFBP-3 in childhood

scientific article published on 01 March 2020

Biology of pregnancy-associated plasma protein-A in relation to prenatal diagnostics: an overview.

scientific article published on September 2010

Calmodulin mutations causing catecholaminergic polymorphic ventricular tachycardia confer opposing functional and biophysical molecular changes

scientific article published on 14 January 2015

Cell surface detachment of pregnancy-associated plasma protein-A requires the formation of intermolecular proteinase-inhibitor disulfide bonds and glycosaminoglycan covalently bound to the inhibitor

scientific article published on 04 December 2006

Cell surface targeting of pregnancy-associated plasma protein A proteolytic activity. Reversible adhesion is mediated by two neighboring short consensus repeats.

scientific article published on 4 October 2002

Circulating human pregnancy-associated plasma protein-A is disulfide-bridged to the proform of eosinophil major basic protein

scientific article (publication date: 15 June 1993)

Complete cDNA sequence of the preproform of human pregnancy-associated plasma protein-A. Evidence for expression in the brain and induction by cAMP

scientific article

Complex of pregnancy-associated plasma protein-A and the proform of eosinophil major basic protein. Disulfide structure and carbohydrate attachment

scientific article (publication date: 24 January 2003)

Conformational changes in tertiary structure near the ligand binding site of an integrin I domain.

scientific article published on March 1999

Corrigendum: Insulin- like Growth Factor-Binding Protein Action in Bone Tissue: A Key Role for Pregnancy- Associated Plasma Protein-A

scientific article published on 04 September 2018

Cytokine stimulation of pregnancy-associated plasma protein A expression in human coronary artery smooth muscle cells: inhibition by resveratrol.

scientific article published on January 2006

Depot-specific and GH-dependent regulation of IGF binding protein-4, pregnancy-associated plasma protein-A, and stanniocalcin-2 in murine adipose tissue

scientific article published on 2 February 2018

Development of a recombinant antibody towards PAPP-A for immunohistochemical use in multiple animal species.

scientific article published on 12 December 2013

Differential Impact of Glucose Administered Intravenously and Orally on Circulating miR-375 Levels in Human Subjects

scientific article

Differential Nanoparticle Sequestration by Macrophages and Scavenger Endothelial Cells Visualized in Vivo in Real-Time and at Ultrastructural Resolution

scientific article published on 30 January 2020

Disturbed Laminar Blood Flow Vastly Augments Lipoprotein Retention in the Artery Wall: A Key Mechanism Distinguishing Susceptible From Resistant Sites.

scientific article published on 16 July 2015

Double-monoclonal immunofluorometric assays for pregnancy-associated plasma protein A/proeosinophil major basic protein (PAPP-A/proMBP) complex in first-trimester maternal serum screening for Down syndrome

scientific article published on 01 December 1997

Duplication and diversification of the hypoxia-inducible IGFBP-1 gene in zebrafish

scientific article

Early developmental expression of Mus musculus zinc finger RNA-binding protein compared to orthologs in Caenorhabditis elegans and Danio rerio and subcellular localization of Mus musculus and Caenorhabditis elegans zinc finger RNA-binding protein in

scientific article published on 22 November 2010

Effect of pregnancy-associated plasma protein-A (PAPP-A) single-nucleotide polymorphisms on the level and activity of PAPP-A and the hormone profile in fluid from normal human small antral follicles.

scientific article published on 25 October 2016

Effects of Mutated Pregnancy-Associated Plasma Protein-A on Atherosclerotic Lesion Development in Mice

scientific article published on November 16, 2012

Effects of Prednisolone on Serum and Tissue Fluid IGF-I Receptor Activation and Post-Receptor Signaling in Humans.

scientific article

Endogenous Natural Complement Inhibitor Regulates Cardiac Development

scientific article published on 3 March 2017

Evidence that the insulin-like growth factor binding protein-4 protease in human ovarian follicular fluid is pregnancy associated plasma protein-A

scientific article published on 01 December 1999

Experimental support for a β-propeller domain in integrin α-subunits and a calcium binding site on its lower surface

scientific article published on April 28, 1998

Expression of recombinant murine pregnancy-associated plasma protein-A (PAPP-A) and a novel variant (PAPP-Ai) with differential proteolytic activity

scientific journal article

Expression of the Insulin-like Growth Factor system in first and second trimester human embryonic and fetal gonads

scientific article published on 29 July 2020

First trimester PAPP-A2, PAPP-A and hCGβ in small-for-gestational-age pregnancies.

scientific article

Folding and function of I domain-deleted Mac-1 and lymphocyte function-associated antigen-1.

scientific article

Formation of high-molecular-weight angiotensinogen during pregnancy is a result of competing redox reactions with the proform of eosinophil major basic protein.

scientific article published in January 2013

Haptoglobin-related protein is a high-affinity hemoglobin-binding plasma protein.

scientific article

IGF dependent modulation of IGF binding protein (IGFBP) proteolysis by pregnancy-associated plasma protein-A (PAPP-A): multiple PAPP-A-IGFBP interaction sites.

scientific article published in March 2013

Identification and regulation of the IGFBP-4 protease and its physiological inhibitor in human trophoblasts and endometrial stroma: evidence for paracrine regulation of IGF-II bioavailability in the placental bed during human implantation.

scientific article

Identification of angiotensinogen and complement C3dg as novel proteins binding the proform of eosinophil major basic protein in human pregnancy serum and plasma

scientific article

Identification of transglutaminase reactive residues in human osteopontin and their role in polymerization

scientific article

Indirect targeting of IGF receptor signaling in vivo by substrate-selective inhibition of PAPP-A proteolytic activity

scientific article

Insulin- like Growth Factor-Binding Protein Action in Bone Tissue: A Key Role for Pregnancy- Associated Plasma Protein-A.

scientific article published on 16 February 2018

Insulin-Like Growth Factor Binding Protein 4 Fragments Provide Incremental Prognostic Information on Cardiovascular Events in Patients With ST-Segment Elevation Myocardial Infarction

scientific article published on 17 March 2017

Insulin-Like Growth Factor Bioactivity, Stanniocalcin-2, Pregnancy-Associated Plasma Protein-A, and IGF-Binding Protein-4 in Pleural Fluid and Serum From Patients With Pulmonary Disease

scientific article

Insulin-like growth factor binding protein-4 protease produced by smooth muscle cells increases in the coronary artery after angioplasty

scientific article published on 01 March 2001

Isolation and characterization of circulating complex between human pregnancy-associated plasma protein-A and proform of eosinophil major basic protein

scientific article published on 01 December 1994

LRP1 controls biosynthetic and endocytic trafficking of neuronal prion protein

scientific article published on 19 February 2008

Lactation opposes pappalysin-1-driven pregnancy-associated breast cancer.

scientific article published on 7 March 2016

Localization and regulation of pregnancy-associated plasma protein a expression in healing human skin.

scientific article published in September 2003

Localization of disulfide bridges and free sulfhydryl groups in human eosinophil granule major basic protein

scientific article

Location and nature of carbohydrate groups in proform of human major basic protein isolated from pregnancy serum

scientific article

Loss-of-activity-mutation in the cardiac chloride-bicarbonate exchanger AE3 causes short QT syndrome.

scientific article published on 22 November 2017

Metalloproteinase PAPP-A regulation of IGF-1 contributes to polycystic kidney disease pathogenesis

scientific article published on 27 February 2020

Metalloproteinase pregnancy-associated plasma protein A is a critical growth regulatory factor during fetal development.

scientific article published in March 2004

Mice deficient in PAPP-A show resistance to the development of diabetic nephropathy

scientific article published on 06 September 2013

Molecular cloning and characterization of porcine Na⁺/K⁺-ATPase isoforms α1, α2, α3 and the ATP1A3 promoter

scientific article

Mutations in pregnancy-associated plasma protein A2 cause short stature due to low IGF-I availability

scientific article published on 22 February 2016

Netazepide Inhibits Expression of Pappalysin 2 in Type 1 Gastric Neuroendocrine Tumors

scientific article published on 28 January 2020

OR07-5 A Cross-Sectional Study of IGF-I Bioavailability through Childhood: Associations with PAPP-A2 and Anthropometric Data.

scientific article

One level up: abnormal proteolytic regulation of IGF activity plays a role in human pathophysiology

scientific article published on 11 August 2017

PAPP-A and IGFBP-4 fragment levels in patients with ST-elevation myocardial infarction treated with heparin and PCI.

scientific article

PAPP-A and cancer

scientific article published on 01 July 2018

PAPP-A and the IGF system

scientific article published on 4 May 2016

PAPP-A and the IGF system in atherosclerosis: what's up, what's down?

scientific article published on 13 September 2019

PAPP-A proteolytic activity enhances IGF bioactivity in ascites from women with ovarian carcinoma

scientific article published on 24 August 2015

PAPP-A, IGFBP-4 and IGF-II are secreted by human adipose tissue cultures in a depot-specific manner

scientific article published in September 2016

PAPP-A: a promising therapeutic target for healthy longevity.

scientific article published on 29 December 2016

Papp-a2 modulates development of cranial cartilage and angiogenesis in zebrafish embryos

scientific article published on 18 September 2014

Plasma C3d levels of young farmers correlate with respirable dust exposure levels during normal work in swine confinement buildings.

scientific article published in January 2003

Pregnancy-Associated Plasma Protein-A (PAPP-A) in Ewing Sarcoma: Role in Tumor Growth and Immune Evasion

scientific article published on 01 September 2019

Pregnancy-Associated Plasma Protein-A (PAPP-A) in Ovine, Bovine, Porcine, and Equine Ovarian Follicles: Involvement in IGF Binding Protein-4 Proteolytic Degradation and mRNA Expression During Follicular Development

scientific article published on 01 December 2001

Pregnancy-Associated Plasma Protein-A Is Markedly Expressed by Monocyte-Macrophage Cells in Vulnerable and Ruptured Carotid Atherosclerotic Plaques

article

Pregnancy-Associated Plasma Protein-A2 and Anthropometry, Lifestyle, and Biochemical Factors in a Human Adult Population

scientific article published on 5 September 2017

Pregnancy-associated Plasma Protein A (PAPP-A) Modulates the Early Developmental Rate in Zebrafish Independently of Its Proteolytic Activity

scientific article published on February 19, 2013

Pregnancy-associated plasma protein A in human ovarian follicles and its association with intrafollicular hormone levels.

scientific article published on 18 August 2015

Pregnancy-associated plasma protein A proteolytic activity is associated with the human placental trophoblast cell membrane.

scientific article published in November 2002

Pregnancy-associated plasma protein a gene expression as a target of inflammatory cytokines.

scientific article published on 4 December 2003

Pregnancy-associated plasma protein-A (PAPP-A) cleaves insulin-like growth factor binding protein (IGFBP)-5 independent of IGF: implications for the mechanism of IGFBP-4 proteolysis by PAPP-A

scientific journal article

Pregnancy-associated plasma protein-A (PAPP-A) expression and insulin-like growth factor binding protein-4 protease activity in normal and malignant ovarian surface epithelial cells.

scientific article published on July 2004

Pregnancy-associated plasma protein-A expression in human breast cancer

scientific article

Pregnancy-associated plasma protein-A is involved in insulin-like growth factor binding protein-2 (IGFBP-2) proteolytic degradation in bovine and porcine preovulatory follicles: identification of cleavage site and characterization of IGFBP-2 degrada

scientific article published on 01 January 2003

Pregnancy-associated plasma protein-a is the insulin-like growth factor binding protein-4 protease secreted by human ovarian granulosa cells and is a marker of dominant follicle selection and the corpus luteum

scientific article published on 01 May 2001

Prognostic relevance and performance characteristics of serum IGFBP-2 and PAPP-A in women with breast cancer: a long-term Danish cohort study.

scientific article

Proteolytic degradation of IGF-binding protein (IGFBP)-2 in equine ovarian follicles: involvement of pregnancy-associated plasma protein-A (PAPP-A) and association with dominant but not subordinated follicles

scientific article published on 01 September 2004

Proteolytic processing of anti-Müllerian hormone differs between human fetal testes and adult ovaries.

scientific article

Quantification and characterization of pregnancy-associated complexes of angiotensinogen and the proform of eosinophil major basic protein in serum and amniotic fluid

scientific article published on 01 August 2000

Quantification of proteolytically active pregnancy-associated plasma protein-A with an assay based on quenched fluorescence

scientific article published on 15 March 2007

Rare and low-frequency coding variants alter human adult height

scientific article (publication date: February 2017)

Real-time measurement in living cells of insulin-like growth factor activity using bioluminescence resonance energy transfer.

scientific article published on June 2005

Recombinant PAPP-A resistant insulin-like growth factor binding protein 4 (dBP4) inhibits angiogenesis and metastasis in a murine model of breast cancer

article

Regulation of Human ADAM 12 Protease by the Prodomain

scientific article published in Journal of Biological Chemistry

Relationship among pregnancy associated plasma protein-A levels, clinical characteristics, and coronary artery disease extent in patients with chronic stable angina pectoris

scientific article published on 29 July 2005

Reply: Methodological considerations in measuring different AMH splice forms using ELISA: validity of proAMH ELISA

scientific article published on 09 March 2016

Screening for Down's syndrome in early and late first and second trimester using six maternal serum markers.

scientific article published in January 2004

Severe preeclampsia-related changes in gene expression at the maternal-fetal interface include sialic acid-binding immunoglobulin-like lectin-6 and pappalysin-2.

scientific article published on 25 September 2008

Simple and reliable procedure for PCR amplification of genomic DNA from yeast cells using short sequencing primers

scientific article published on 01 June 1997

Stanniocalcin-1 Potently Inhibits the Proteolytic Activity of the Metalloproteinase Pregnancy-associated Plasma Protein-A.

scientific article published on 20 July 2015

Stanniocalcin-2 inhibits mammalian growth by proteolytic inhibition of the insulin-like growth factor axis

scientific article

Stress-activated signaling pathways mediate the stimulation of pregnancy-associated plasma protein-A expression in cultured human fibroblasts.

scientific article published on 3 November 2005

Targeted Inhibition of Pregnancy-Associated Plasma Protein-A Activity Reduces Atherosclerotic Plaque Burden in Mice.

scientific article published on 5 January 2016

Temporal course of pregnancy-associated plasma protein-A in angioplasty-treated ST-elevation myocardial infarction patients and potential significance of concomitant heparin administration.

scientific article published on 9 October 2008

The IGF system in patients with type 2 diabetes: associations with markers of cardiovascular target organ damage.

scientific article published on 8 February 2017

The insulin-like growth factor (IGF)-dependent IGF binding protein-4 protease secreted by human fibroblasts is pregnancy-associated plasma protein-A

scientific article

The proform of eosinophil major basic protein: a new maternal serum marker for Down syndrome

scientific article published on 01 October 1999

The proform of the eosinophil major basic protein binds the cell surface through a site distinct from its C-type lectin ligand-binding region

scientific article published on 28 August 2006

The proteolytic activity of pregnancy-associated plasma protein-A is potentially regulated by stanniocalcin-1 and -2 during human ovarian follicle development

scientific article

The role of PAPP-A in the IGF system: location, location, location.

scientific article published on 25 January 2015

The status of half-cystine residues and locations of N-glycosylated asparagine residues in human eosinophil peroxidase

scientific article published on 01 July 2000

The structural basis of calcium transport by the calcium pump

scientific article

The structure of the beta-propeller domain and C-terminal region of the integrin alphaM subunit. Dependence on beta subunit association and prediction of domains.

scientific article published on June 1998

Transcription profile of the insulin-like growth factor signaling pathway during human ovarian follicular development

scientific article published on 15 March 2019

Transglutaminase 2-Catalyzed Intramolecular Cross-Linking of Osteopontin.

scientific article published on 17 December 2015

Treatment With Recombinant Human Insulin-Like Growth Factor-1 Improves Growth in Patients With PAPP-A2 Deficiency

scientific article published on 20 September 2016

Unstable carotid plaque: biochemical and cellular marker of vulnerability

scientific article published in May 2003

Zebrafish as a novel model to assess Na+/K(+)-ATPase-related neurological disorders.

scientific article published on October 2013

α3Na+/K+-ATPase Deficiency Causes Brain Ventricle Dilation and Abrupt Embryonic Motility in Zebrafish

scientific article published on February 11, 2013