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List of works by Daniel Paape

Changes to cholesterol trafficking in macrophages by Leishmania parasites infection

scientific article published on 27 March 2017

Contribution of proteomics of Leishmania spp. to the understanding of differentiation, drug resistance mechanisms, vaccine and drug development ⬇️

scientific article published on May 19, 2011

Discovery of high affinity inhibitors of Leishmania donovani N-myristoyltransferase.

scientific article published on 19 August 2015

Diverged composition and regulation of the Trypanosoma brucei origin recognition complex that mediates DNA replication initiation

scientific article published on 06 March 2016

Gel free analysis of the proteome of intracellular Leishmania mexicana

scientific article published on 10 November 2009

Genetic validation of Leishmania genes essential for amastigote survival in vivo using N-myristoyltransferase as a model

scientific article published on 14 March 2020

Genome-wide mapping reveals single-origin chromosome replication in Leishmania, a eukaryotic microbe.

scientific article published on 19 October 2015

Global Profiling and Inhibition of Protein Lipidation in Vector and Host Stages of the Sleeping Sickness Parasite Trypanosoma brucei ⬇️

scientific article

Global analysis of protein N-myristoylation and exploration of N-myristoyltransferase as a drug target in the neglected human pathogen Leishmania donovani ⬇️

scientific article

Mapping replication dynamics in Trypanosoma brucei reveals a link with telomere transcription and antigenic variation.

scientific article published on 26 May 2016

Real-time imaging of Leishmania mexicana-infected early phagosomes: a study using primary macrophages generated from green fluorescent protein-Rab5 transgenic mice

scientific article published on 16 October 2008

Structure-based design of potent and selective Leishmania N-myristoyltransferase inhibitors

scientific article published on October 2014

Targeting the trypanosome kinetochore with CLK1 protein kinase inhibitors

scientific article published on 13 July 2020

The Leishmania major BBSome subunit BBS1 is essential for parasite virulence in the mammalian host.

scientific article published on 17 September 2013

Transgenic, fluorescent Leishmania mexicana allow direct analysis of the proteome of intracellular amastigotes

scientific article

Using a non-image-based medium-throughput assay for screening compounds targeting N-myristoylation in intracellular Leishmania amastigotes

scientific article (publication date: December 2014)

Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs

scientific article published on 03 November 2020

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