List of works - Edoardo Missiaglia

A Composite Gene Expression Signature Optimizes Prediction of Colorectal Cancer Metastasis and Outcome.

scientific article published on 7 October 2015

Activating mutations in genes related to TCR signaling in angioimmunoblastic and other follicular helper T-cell-derived lymphomas.

scientific article

Activation of the hedgehog pathway confers a poor prognosis in embryonal and fusion gene-negative alveolar rhabdomyosarcoma

article

Additional genetic risk factors for venous thromboembolism in carriers of the factor V Leiden mutation.

scientific article published in December 1998

Allelotype of ampulla of Vater cancer: highly frequent involvement of chromosome 11

article

An additional unique candidate mutation (G2470A; M740I) in the original families with von Willebrand disease type 2 M Vicenza and the G3864A (R1205H) mutation

scientific article published on 01 August 2000

Analysis of gene expression in cancer cell lines identifies candidate markers for pancreatic tumorigenesis and metastasis

scientific article

Antitumor activity of sustained N-myc reduction in rhabdomyosarcomas and transcriptional block by antigene therapy

scientific article

BRAF V600E Mutant Colorectal Cancer Subtypes Based on Gene Expression

scientific article published on 27 June 2016

Clinical Application of Prognostic Gene Expression Signature in Fusion Gene-Negative Rhabdomyosarcoma: A Report from the Children's Oncology Group

scientific article

Distal and proximal colon cancers differ in terms of molecular, pathological, and clinical features.

scientific article

Distinct effects of ligand-induced PDGFRα and PDGFRβ signaling in the human rhabdomyosarcoma tumor cell and stroma cell compartments.

scientific article published on 21 January 2013

Distinct roles for miR-1 and miR-133a in the proliferation and differentiation of rhabdomyosarcoma cells

scientific article

Factor V Leiden mutation carriership and venous thromboembolism in polycythemia vera and essential thrombocythemia

scientific article published in September 2002

Fusion gene-negative alveolar rhabdomyosarcoma is clinically and molecularly indistinguishable from embryonal rhabdomyosarcoma.

scientific article published on 29 March 2010

Genetic drivers of oncogenic pathways in molecular subgroups of peripheral T-cell lymphoma

scientific article published on 19 February 2019

Genomic copy number and expression patterns in testicular germ cell tumours.

scientific article published on 4 December 2007

Genomic gain and over expression of CCL2 correlate with vascular invasion in stage I non-seminomatous testicular germ-cell tumours.

scientific article

Genomic imbalances in rhabdomyosarcoma cell lines affect expression of genes frequently altered in primary tumors: an approach to identify candidate genes involved in tumor development

scientific article

Glypican-3 is expressed in rhabdomyosarcomas but not adult spindle cell and pleomorphic sarcomas.

scientific article

HES6 enhances the motility of alveolar rhabdomyosarcoma cells.

scientific article

Immunohistochemistry as a valuable tool to assess CD30 expression in peripheral T-cell lymphomas: high correlation with mRNA levels

scientific article published on 15 September 2014

Inconvenience of convenience cohorts--letter.

scientific article published on 26 June 2012

JARID2 is a direct target of the PAX3-FOXO1 fusion protein and inhibits myogenic differentiation of rhabdomyosarcoma cells.

scientific article

Low expression of ARHI is associated with shorter progression-free survival in pancreatic endocrine tumors

scientific article published on March 2007

MFG-E8/lactadherin regulates cyclins D1/D3 expression and enhances the tumorigenic potential of mammary epithelial cells.

scientific article

MicroRNA Expression Abnormalities in Pancreatic Endocrine and Acinar Tumors Are Associated With Distinctive Pathologic Features and Clinical Behavior

article

Minimum regions of genomic imbalance in stage I testicular embryonal carcinoma and association of 22q loss with relapse.

scientific article

Molecular alterations in pancreatic carcinoma: expression profiling shows that dysregulated expression of S100 genes is highly prevalent

scientific article

PAX3/FOXO1 fusion gene status is the key prognostic molecular marker in rhabdomyosarcoma and significantly improves current risk stratification.

scientific article published on 26 March 2012

Pancreatic endocrine tumors: expression profiling evidences a role for AKT-mTOR pathway

scientific article

Prime-boost vaccines encoding an intracellular idiotype/GM-CSF fusion protein induce protective cell-mediated immunity in murine pre-B cell leukemia.

scientific article

Role of disease-causing genes in sporadic pancreatic endocrine tumors:MEN1andVHL

article

Sex chromosome anomalies in pancreatic endocrine tumors

Targeting the insulin-like growth factor pathway in rhabdomyosarcomas: rationale and future perspectives.

scientific article

The Hippo effector TAZ (WWTR1) transforms myoblasts and TAZ abundance is associated with reduced survival in embryonal rhabdomyosarcoma.

scientific article published on 17 May 2016

The Hippo transducer YAP1 transforms activated satellite cells and is a potent effector of embryonal rhabdomyosarcoma formation.

scientific article published on 31 July 2014

The SIB Swiss Institute of Bioinformatics' resources: focus on curated databases

scientific article (publication date: 4 January 2016)

The VITA Project: C677T mutation in the methylene‐tetrahydrofolate reductase gene and risk of venous thromboembolism ⬇️

scientific article published on June 1, 1997

The VITA project: phenotypic resistance to activated protein C and FV Leiden mutation in the general population. Vicenza Thrombophilia and Atherosclerosis.

scientific article published in August 1997

The VITA project: prothrombin G20210A mutation and venous thromboembolism in the general population

scientific article published on 01 November 1999

The consensus molecular subtypes of colorectal cancer

scientific article

Thrombosis in patients with heterozygous and homozygous factor XII deficiency is not explained by the associated presence of factor V Leiden

scientific article published on 01 August 1996

Type II enteropathy-associated T-cell lymphoma features a unique genomic profile with highly recurrent SETD2 alterations

scientific article published on 07 September 2016

VGLL3 operates via TEAD1, TEAD3 and TEAD4 to influence myogenesis in skeletal muscle

scientific article published on 05 July 2019

List of works by Edoardo Missiaglia

A Composite Gene Expression Signature Optimizes Prediction of Colorectal Cancer Metastasis and Outcome.

Activating mutations in genes related to TCR signaling in angioimmunoblastic and other follicular helper T-cell-derived lymphomas.

Activation of the hedgehog pathway confers a poor prognosis in embryonal and fusion gene-negative alveolar rhabdomyosarcoma

Additional genetic risk factors for venous thromboembolism in carriers of the factor V Leiden mutation.

Allelotype of ampulla of Vater cancer: highly frequent involvement of chromosome 11

An additional unique candidate mutation (G2470A; M740I) in the original families with von Willebrand disease type 2 M Vicenza and the G3864A (R1205H) mutation

Analysis of gene expression in cancer cell lines identifies candidate markers for pancreatic tumorigenesis and metastasis

Antitumor activity of sustained N-myc reduction in rhabdomyosarcomas and transcriptional block by antigene therapy

BRAF V600E Mutant Colorectal Cancer Subtypes Based on Gene Expression

Clinical Application of Prognostic Gene Expression Signature in Fusion Gene-Negative Rhabdomyosarcoma: A Report from the Children's Oncology Group

Distal and proximal colon cancers differ in terms of molecular, pathological, and clinical features.

Distinct effects of ligand-induced PDGFRα and PDGFRβ signaling in the human rhabdomyosarcoma tumor cell and stroma cell compartments.

Distinct roles for miR-1 and miR-133a in the proliferation and differentiation of rhabdomyosarcoma cells

Factor V Leiden mutation carriership and venous thromboembolism in polycythemia vera and essential thrombocythemia

Fusion gene-negative alveolar rhabdomyosarcoma is clinically and molecularly indistinguishable from embryonal rhabdomyosarcoma.

Genetic drivers of oncogenic pathways in molecular subgroups of peripheral T-cell lymphoma

Genomic copy number and expression patterns in testicular germ cell tumours.

Genomic gain and over expression of CCL2 correlate with vascular invasion in stage I non-seminomatous testicular germ-cell tumours.

Genomic imbalances in rhabdomyosarcoma cell lines affect expression of genes frequently altered in primary tumors: an approach to identify candidate genes involved in tumor development

Glypican-3 is expressed in rhabdomyosarcomas but not adult spindle cell and pleomorphic sarcomas.

HES6 enhances the motility of alveolar rhabdomyosarcoma cells.

Immunohistochemistry as a valuable tool to assess CD30 expression in peripheral T-cell lymphomas: high correlation with mRNA levels

Inconvenience of convenience cohorts--letter.

JARID2 is a direct target of the PAX3-FOXO1 fusion protein and inhibits myogenic differentiation of rhabdomyosarcoma cells.

Low expression of ARHI is associated with shorter progression-free survival in pancreatic endocrine tumors

MFG-E8/lactadherin regulates cyclins D1/D3 expression and enhances the tumorigenic potential of mammary epithelial cells.

MicroRNA Expression Abnormalities in Pancreatic Endocrine and Acinar Tumors Are Associated With Distinctive Pathologic Features and Clinical Behavior

Minimum regions of genomic imbalance in stage I testicular embryonal carcinoma and association of 22q loss with relapse.

Molecular alterations in pancreatic carcinoma: expression profiling shows that dysregulated expression of S100 genes is highly prevalent

PAX3/FOXO1 fusion gene status is the key prognostic molecular marker in rhabdomyosarcoma and significantly improves current risk stratification.

Pancreatic endocrine tumors: expression profiling evidences a role for AKT-mTOR pathway

Prime-boost vaccines encoding an intracellular idiotype/GM-CSF fusion protein induce protective cell-mediated immunity in murine pre-B cell leukemia.

Role of disease-causing genes in sporadic pancreatic endocrine tumors:MEN1andVHL

Sex chromosome anomalies in pancreatic endocrine tumors

Targeting the insulin-like growth factor pathway in rhabdomyosarcomas: rationale and future perspectives.

The Hippo effector TAZ (WWTR1) transforms myoblasts and TAZ abundance is associated with reduced survival in embryonal rhabdomyosarcoma.

The Hippo transducer YAP1 transforms activated satellite cells and is a potent effector of embryonal rhabdomyosarcoma formation.

The SIB Swiss Institute of Bioinformatics' resources: focus on curated databases

The VITA Project: C677T mutation in the methylene‐tetrahydrofolate reductase gene and risk of venous thromboembolism ⬇️

The VITA project: phenotypic resistance to activated protein C and FV Leiden mutation in the general population. Vicenza Thrombophilia and Atherosclerosis.

The VITA project: prothrombin G20210A mutation and venous thromboembolism in the general population

The consensus molecular subtypes of colorectal cancer

Thrombosis in patients with heterozygous and homozygous factor XII deficiency is not explained by the associated presence of factor V Leiden

Type II enteropathy-associated T-cell lymphoma features a unique genomic profile with highly recurrent SETD2 alterations

VGLL3 operates via TEAD1, TEAD3 and TEAD4 to influence myogenesis in skeletal muscle