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List of works by Alessandra Fragale

3D Microfluidic model for evaluating immunotherapy efficacy by tracking dendritic cell behaviour toward tumor cells

scientific article

A competitive PCR-based method to measure human fibroblast growth factor receptor 1-4 (FGFR1-4) gene expression.

scientific article

A multidisciplinary study using in vivo tumor models and microfluidic cell-on-chip approach to explore the cross-talk between cancer and immune cells

scientific article published on 6 March 2014

Activin stimulates Sertoli cell proliferation in a defined period of rat testis development.

scientific article

Age-dependent activin receptor expression pinpoints activin A as a physiological regulator of rat Sertoli cell proliferation

scientific article published on December 1, 2001

Antitumor Effects of Epidrug/IFNα Combination Driven by Modulated Gene Signatures in Both Colorectal Cancer and Dendritic Cells.

scientific article published on 14 June 2017

CSA and CSB play a role in the response to DNA breaks.

scientific article published on 29 January 2018

Colorectal cancer in mice genetically deficient in the mucin Muc2

scientific journal article

Critical Role of IRF-8 in Negative Regulation of TLR3 Expression by Src Homology 2 Domain-Containing Protein Tyrosine Phosphatase-2 Activity in Human Myeloid Dendritic Cells

scientific article published on January 10, 2011

Decreased proliferation and altered differentiation in osteoblasts from genetically and clinically distinct craniosynostotic disorders

scientific article published on May 1999

HIV-1, interferon and the interferon regulatory factor system: an interplay between induction, antiviral responses and viral evasion.

scientific article published on 27 June 2012

IFN-α potentiates the direct and immune-mediated antitumor effects of epigenetic drugs on both metastatic and stem cells of colorectal cancer

scientific article published on 25 March 2016

IRF-1 deficiency skews the differentiation of dendritic cells toward plasmacytoid and tolerogenic features.

scientific article published on 11 September 2006

IRF-8 controls melanoma progression by regulating the cross talk between cancer and immune cells within the tumor microenvironment.

scientific article published on December 2012

Identification and cellular localisation of voltage-operated calcium channels in immature rat testis

scientific article published on 01 April 2000

Impaired myelopoiesis in mice devoid of interferon regulatory factor 1.

scientific article published in November 2004

Increased Production of Cytokines and Growth Factors by Aortic Allografts: A Possible Explanation for Myointimal Hyperplasia Formation

scientific article published on 01 January 1999

Mutations in ZBTB20 cause Primrose syndrome

scientific article

Noonan syndrome-associated SHP2/PTPN11 mutants cause EGF-dependent prolonged GAB1 binding and sustained ERK2/MAPK1 activation

scientific article published on March 2004

Role of Interferon Regulatory Factor 1 in Governing Treg Depletion, Th1 Polarization, Inflammasome Activation and Antitumor Efficacy of Cyclophosphamide.

scientific article published on 4 October 2017

Shear stress induces changes in the morphology and cytoskeleton organisation of arterial endothelial cells

scientific article published on 01 January 1995

Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia

scientific article published in June 2003

Somatically acquired JAK1 mutations in adult acute lymphoblastic leukemia

scientific article

Targeting CXCR4 reverts the suppressive activity of T-regulatory cells in renal cancer.

scientific article published on 19 August 2017