List of works - Ainoleena Turku

A NanoBRET-Based Binding Assay for Smoothened Allows Real-time Analysis of Ligand Binding and Distinction of Two Binding Sites for BODIPY-cyclopamine

scientific article published on 09 November 2019

Asymmetry in catalysis by membrane-bound pyrophosphatase demonstrated by a nonphosphorus allosteric inhibitor

scientific article published on 22 May 2019

Azulene-based compounds for targeting orexin receptors

scientific article published on 20 July 2018

Defining Dynamics of Membrane-Bound Pyrophosphatases by Experimental and Computational Single-Molecule FRET

scientific article published in 2018

Frizzled BRET sensors based on bioorthogonal labeling of unnatural amino acids reveal WNT-induced dynamics of the cysteine-rich domain

scientific article published on 10 November 2021

Insights into the mechanism of membrane pyrophosphatases by combining experiment and computer simulation. ⬇️

scientific article published on 03 March 2017

Modeling of the OX1R-orexin-A complex suggests two alternative binding modes.

scientific article published on 9 May 2015

Molecular Pharmacology of Class F Receptor Activation

scientific article published on 07 October 2019

Orexin receptor agonist Yan 7874 is a weak agonist of orexin/hypocretin receptors and shows orexin receptor-independent cytotoxicity

scientific article

Pharmacological characterization of the orexin/hypocretin receptor agonist Nag 26

scientific article published on 05 September 2018

Pharmacophore Model To Discover OX1 and OX2 Orexin Receptor Ligands.

scientific article published on 22 August 2016

Rare genetic variability in human drug target genes modulates drug response and can guide precision medicine

scientific article published on 01 September 2021

Residue 6.43 defines receptor function in class F GPCRs

scientific article published on 24 June 2021

Scaffold hopping from (5-hydroxymethyl) isophthalates to multisubstituted pyrimidines diminishes binding affinity to the C1 domain of protein kinase C.

scientific article published on 11 April 2018

Screening for Thermotoga maritima Membrane-Bound Pyrophosphatase Inhibitors

scientific article published on 23 November 2019

Structural insight into small molecule action on Frizzleds

scientific article published on 21 January 2020

Structure-Activity Relationships of 1-Benzoylazulenes at the OX1 and OX2 Orexin Receptors

scientific article published on 02 April 2019

List of works by Ainoleena Turku