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List of works by Richard Adams

A clinical review of the investigation and management of carcinoma of unknown primary in a single cancer network.

scientific article published on February 2007

A feasibility study testing four hypotheses with phase II outcomes in advanced colorectal cancer (MRC FOCUS3): a model for randomised controlled trials in the era of personalised medicine? ⬇️

scientific article

A prospective comparison of multidisciplinary treatment of oesophageal cancer with curative intent in a UK cancer network

scientific article published on 22 November 2006

A rectal cancer feasibility study with an embedded phase III trial design assessing magnetic resonance tumour regression grade (mrTRG) as a novel biomarker to stratify management by good and poor response to chemoradiotherapy (TRIGGER): study protoc ⬇️

scientific article published on 29 August 2017

Addition of cetuximab to oxaliplatin-based first-line combination chemotherapy for treatment of advanced colorectal cancer: results of the randomised phase 3 MRC COIN trial ⬇️

scientific article published on June 5, 2011

Anal cancer: developing an intensity-modulated radiotherapy solution for ACT2 fractionation

scientific article published on 31 August 2014

Aspirin as an adjuvant treatment for cancer: feasibility results from the Add-Aspirin randomised trial

scientific article published on 30 August 2019

Association of Coloproctology of Great Britain & Ireland (ACPGBI): Guidelines for the Management of Cancer of the Colon, Rectum and Anus (2017) - Anal Cancer

scientific article published on 01 July 2017

Association of Coloproctology of Great Britain & Ireland (ACPGBI): Guidelines for the Management of Cancer of the Colon, Rectum and Anus (2017) - Multidisciplinary Management

scientific article published on 01 July 2017

Body Mass Index Is Prognostic in Metastatic Colorectal Cancer: Pooled Analysis of Patients From First-Line Clinical Trials in the ARCAD Database.

scientific article

CRIB--the use of cardiac rehabilitation services to aid the recovery of patients with bowel cancer: a pilot randomised controlled trial (RCT) with embedded feasibility study.

scientific article published on 18 February 2014

Cetuximab therapy in first-line metastatic colorectal cancer and intermittent palliative chemotherapy: review of the COIN trial.

scientific article published on August 2008

Chemotherapy-free intervals for patients with metastatic colorectal cancer remain an option

scientific article published on 03 May 2010

Clinical Calculator for Early Mortality in Metastatic Colorectal Cancer: An Analysis of Patients From 28 Clinical Trials in the Aide et Recherche en Cancérologie Digestive Database ⬇️

scientific article

Clinical development of new drug-radiotherapy combinations ⬇️

scientific article published on June 2016

Clinical endpoints in trials of chemoradiation for patients with anal cancer.

scientific article published in April 2017

Clinicopathological differences and survival outcomes with first-line therapy in patients with left-sided colon cancer and rectal cancer: Pooled analysis of 2879 patients from AGITG (MAX), COIN, FOCUS2, OPUS, CRYSTAL and COIN-B trials in the ARCAD da ⬇️

scientific article published on 27 September 2018

Comprehensive pharmacogenetic profiling of the epidermal growth factor receptor pathway for biomarkers of response to, and toxicity from, cetuximab

scientific article

Consensus statement on essential patient characteristics in systemic treatment trials for metastatic colorectal cancer: Supported by the ARCAD Group

scientific article published on 22 June 2018

Critical research gaps and recommendations to inform research prioritisation for more effective prevention and improved outcomes in colorectal cancer. ⬇️

scientific article published in January 2018

Derived neutrophil lymphocyte ratio is predictive of survival from intermittent therapy in advanced colorectal cancer: a post hoc analysis of the MRC COIN study

scientific article published on 18 February 2016

Derived neutrophil to lymphocyte ratio as a prognostic factor in patients with advanced colorectal cancer according to RAS and BRAF status: a post-hoc analysis of the MRC COIN study.

scientific article

Does anti-EGFR therapy improve outcome in advanced colorectal cancer? A systematic review and meta-analysis

scientific article

Effect of Modified Vaccinia Ankara-5T4 and Low-Dose Cyclophosphamide on Antitumor Immunity in Metastatic Colorectal Cancer: A Randomized Clinical Trial.

scientific article published on 7 September 2017

End points in anal cancer: hopes for a common language.

scientific article published on 17 March 2014

Epidermal growth factor receptor immunohistochemistry: new opportunities in metastatic colorectal cancer

scientific article

Exome resequencing identifies potential tumor-suppressor genes that predispose to colorectal cancer.

scientific article published on 20 May 2013

First-line selective internal radiotherapy plus chemotherapy versus chemotherapy alone in patients with liver metastases from colorectal cancer (FOXFIRE, SIRFLOX, and FOXFIRE-Global): a combined analysis of three multicentre, randomised, phase 3 tri

scientific article published on 03 August 2017

HER2-HER3 heterodimer quantification by FRET-FLIM and patient subclass analysis of the COIN colorectal trial

scientific article published on 18 December 2019

How health-related quality of life assessment should be used in advanced colorectal cancer clinical trials

scientific article published on 18 April 2017

Image-guided radiotherapy for rectal cancer: a systematic review

scientific article

Imaging for target volume delineation in rectal cancer radiotherapy--a systematic review

scientific article published on 27 October 2011

Individual patient data analysis of progression-free survival versus overall survival as a first-line end point for metastatic colorectal cancer in modern randomized trials: findings from the analysis and research in cancers of the digestive system d

scientific article published in January 2015

Initial Results from the Royal College of Radiologists' UK National Audit of Anal Cancer Radiotherapy 2015. ⬇️

scientific article published on 31 October 2016

Intermittent chemotherapy plus either intermittent or continuous cetuximab for first-line treatment of patients with KRAS wild-type advanced colorectal cancer (COIN-B): a randomised phase 2 trial

scientific article

Intermittent therapy in the palliative treatment of metastatic colorectal cancer.

scientific article published on January 2009

Intermittent versus continuous oxaliplatin and fluoropyrimidine combination chemotherapy for first-line treatment of advanced colorectal cancer: results of the randomised phase 3 MRC COIN trial ⬇️

scientific article published on June 5, 2011

Investigating the poor outcomes of BRAF-mutant advanced colorectal cancer: analysis from 2530 patients in randomised clinical trials ⬇️

scientific article published on 19 December 2016

Is referral of postsurgical colorectal cancer survivors to cardiac rehabilitation feasible and acceptable? A pragmatic pilot randomised controlled trial with embedded qualitative study.

scientific article

Management of the asymptomatic primary in the palliative treatment of metastatic colorectal cancer.

scientific article published on October 2008

Oxaliplatin/capecitabine vs oxaliplatin/infusional 5-FU in advanced colorectal cancer: the MRC COIN trial.

scientific article

Patterns and Predictors of Relapse Following Radical Chemoradiation Therapy Delivered Using Intensity Modulated Radiation Therapy With a Simultaneous Integrated Boost in Anal Squamous Cell Carcinoma

scientific article published on 17 October 2019

Pharmacogenetic analyses of 2183 patients with advanced colorectal cancer; potential role for common dihydropyrimidine dehydrogenase variants in toxicity to chemotherapy

scientific article published on 13 August 2018

Phenotypic consequences of somatic mutations in the ataxia-telangiectasia mutated gene in non-small cell lung cancer

scientific article published on 2 September 2016

Pre-trial inter-laboratory analytical validation of the FOCUS4 personalised therapy trial ⬇️

scientific article

Predicting response to epidermal growth factor receptor-targeted therapy in colorectal cancer.

scientific article published on April 2007

Prognosis of patients with peritoneal metastatic colorectal cancer given systemic therapy: an analysis of individual patient data from prospective randomised trials from the Analysis and Research in Cancers of the Digestive System (ARCAD) database ⬇️

scientific article

Prognostic factors for recurrence and survival in anal cancer: generating hypotheses from the mature outcomes of the first United Kingdom Coordinating Committee on Cancer Research Anal Cancer Trial (ACT I).

scientific article published on 25 September 2012

Prospective patient stratification into robust cancer-cell intrinsic subtypes from colorectal cancer biopsies ⬇️

scientific article published on 7 February 2018

Session 4: What should we do for poor responders after chemoradiotherapy: bad biology or should the fight go on?

scientific article published on 01 May 2018

Stage-for-stage comparison of definitive chemoradiotherapy, surgery alone and neoadjuvant chemotherapy for oesophageal carcinoma

scientific article published on 01 November 2009

Surveillance of Anal Canal Cancers.

scientific article published on January 2017

Systematic review update of observational studies further supports aspirin role in cancer treatment: Time to share evidence and decision-making with patients?

scientific article published in PLoS ONE

Talking about human papillomavirus and cancer: development of consultation guides through lay and professional stakeholder coproduction using qualitative, quantitative and secondary data

scientific article

Talking about human papillomavirus and cancer: protocol for a patient-centred study to develop scripted consultations

scientific article published on 25 April 2016

The Development of an Umbrella Trial (PLATO) to Address Radiation Therapy Dose Questions in the Locoregional Management of Squamous Cell Carcinoma of the Anus

article published in 2016

The Three-item ALERT-B Questionnaire Provides a Validated Screening Tool to Detect Chronic Gastrointestinal Symptoms after Pelvic Radiotherapy in Cancer Survivors.

scientific article

The physician-patient relationship in the age of precision medicine

scientific article published on 14 September 2018

Toxicity, Tolerability, and Compliance of Concurrent Capecitabine or 5-Fluorouracil in Radical Management of Anal Cancer With Single-dose Mitomycin-C and Intensity Modulated Radiation Therapy: Evaluation of a National Cohort ⬇️

article

What is the quality of economic evaluations of non-drug therapies? A systematic review and critical appraisal of economic evaluations of radiotherapy for cancer. ⬇️

scientific article

Where now for anti-EGF receptor therapies in colorectal cancer?

scientific article

Wide Variation in the Use of Radiotherapy in the Management of Surgically Treated Rectal Cancer Across the English National Health Service ⬇️

scientific article published on 27 February 2016

“Mind the Gap”—The Impact of Variations in the Duration of the Treatment Gap and Overall Treatment Time in the First UK Anal Cancer Trial (ACT I)

article

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