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List of works by Sarah R Needham

A systematic investigation of differential effects of cell culture substrates on the extent of artifacts in single-molecule tracking.

scientific article

A tale of the epidermal growth factor receptor: The quest for structural resolution on cells.

scientific article

Affimer proteins are versatile and renewable affinity reagents ⬇️

scientific article

Automated multidimensional single molecule fluorescence microscopy feature detection and tracking.

scientific article

Determining the geometry of oligomers of the human epidermal growth factor family on cells with 7 nm resolution.

scientific article published on 18 April 2015

Determining the geometry of oligomers of the human epidermal growth factor family on cells with <10 nm resolution.

scientific article published on June 2015

EGFR oligomerization organizes kinase-active dimers into competent signalling platforms

scientific article

Measuring EGFR separations on cells with ~10 nm resolution via fluorophore localization imaging with photobleaching.

scientific article

Multidimensional single-molecule imaging in live cells using total-internal-reflection fluorescence microscopy.

scientific article published in July 2006

Nanometric molecular separation measurements by single molecule photobleaching.

scientific article published on 14 May 2015

Optics clustered to output unique solutions: a multi-laser facility for combined single molecule and ensemble microscopy.

scientific article

Simultaneous widefield single molecule orientation and FRET microscopy in cells.

scientific article

Single-molecule imaging and fluorescence lifetime imaging microscopy show different structures for high- and low-affinity epidermal growth factor receptors in A431 cells.

scientific article

Structure-function relationships and supramolecular organization of the EGFR (epidermal growth factor receptor) on the cell surface.

scientific article published on February 2014

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