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List of works by Antonella Castagna

Ability of different lopinavir genotypic inhibitory quotients to predict 48-week virological response in highly treatment-experienced HIV-infected patients receiving lopinavir/ritonavir

scientific article published in December 2006

Access and response to direct antiviral agents (DAA) in HIV-HCV co-infected patients in Italy: Data from the Icona cohort

scientific article

Active HCV Replication but Not HCV or CMV Seropositive Status Is Associated With Incident and Prevalent Type 2 Diabetes in Persons Living With HIV.

scientific article published on August 2017

All-cause mortality in treated HIV-infected adults with CD4 ≥500/mm3 compared with the general population: evidence from a large European observational cohort collaboration

scientific article published on 28 November 2011

Amprenavir and ritonavir plasma concentrations in HIV-infected patients treated with fosamprenavir/ritonavir with various degrees of liver impairment

scientific article published on 7 August 2007

An observational, retrospective analysis evaluating switching to raltegravir plus abacavir/lamivudine in HIV-1-infected patients: the ORASWIRAL study.

scientific article published on 11 September 2017

Associations of statins and antiretroviral drugs with the onset of type 2 diabetes among HIV-1-infected patients

scientific article

Atazanavir/ritonavir monotherapy: 96 week efficacy, safety and bone mineral density from the MODAt randomized trial

scientific article published on 5 March 2016

B-cell subset alterations and correlated factors in HIV-1 infection

scientific article published on May 2013

Bone mineral density and inflammatory and bone biomarkers after darunavir-ritonavir combined with either raltegravir or tenofovir-emtricitabine in antiretroviral-naive adults with HIV-1: a substudy of the NEAT001/ANRS143 randomised trial

scientific article

Boosted protease inhibitor-including versus a protease inhibitor-sparing regimen in protease inhibitor-resistant HIV-infected patients: 24-week immunological outcome

scientific article published in March 2004

Cardiovascular disease in women with HIV-1 infection

scientific article published on 27 February 2017

Cerebrospinal fluid S-adenosylmethionine (SAMe) and glutathione concentrations in HIV infection Effect of parenteral treatment with SAMe

article

Cerebrospinal fluid analysis for HIV replication and biomarkers of immune activation and neurodegeneration in long-term atazanavir/ritonavir monotherapy treated patients

scientific article published on July 2016

Changes in darunavir/r resistance score after previous failure to tipranavir/r in HIV-1-infected multidrug-resistant patients

scientific article published in February 2009

Clinical and immunological aspects of HIV infection in drug addicts.

scientific article

Clinical, virologic, and immunologic outcomes in lymphoma survivors and in cancer-free, HIV-1-infected patients: a matched cohort study

scientific article published on 26 April 2013

Common genetic variation and the control of HIV-1 in humans

scientific article published in December 2009

Complexity and dynamics of HIV-1 chemokine receptor usage in a multidrug-resistant adolescent

scientific article

Cost analysis of initial highly active antiretroviral therapy regimens for managing human immunodeficiency virus-infected patients according to clinical practice in a hospital setting

scientific article published on 18 December 2013

Cross-resistance Profile of the Novel Integrase Inhibitor Dolutegravir (S/GSK1349572) Using Clonal Viral Variants Selected in Patients Failing Raltegravir

scientific article published in 2011

Cytomegalovirus infection of the central nervous system in patients with AIDS: diagnosis by DNA amplification from cerebrospinal fluid

scientific article published on December 1, 1992

Darunavir for the treatment of HIV infection

article

Death rates in HIV-positive antiretroviral-naive patients with CD4 count greater than 350 cells per microL in Europe and North America: a pooled cohort observational study

scientific article

Determinants of access to experimental antiretroviral drugs in an Italian cohort of patients with HIV: a multilevel analysis

scientific article

Diagnosis of virus-associated opportunistic diseases of the central nervous system in patients with HIV infection by polymerase chain reaction on cerebrospinal fluid.

scientific article published on June 1994

Discontinuation of Initial Antiretroviral Therapy in Clinical Practice: Moving Toward Individualized Therapy

scientific article published on March 2016

Dolutegravir in antiretroviral-experienced patients with raltegravir- and/or elvitegravir-resistant HIV-1: 24-week results of the phase III VIKING-3 study

scientific article

Dolutegravir: a new option for HIV treatment

article

Durability and safety of a novel salvage therapy in R5-tropic HIV-infected patients: maraviroc, raltegravir, etravirine

scientific article published in April 2011

Durability and tolerability of first-line regimens including two nucleoside reverse transcriptase inhibitors and raltegravir or ritonavir boosted-atazanavir or -darunavir: data from the ICONA Cohort

article by Antonella d’Arminio Monforte et al published March 2018 in HIV Clinical Trials

Durability of switch regimens based on rilpivirine or on integrase inhibitors, both in association with tenofovir and emtricitabine, in HIV-infected, virologically suppressed patients

scientific article published on 16 November 2017

Dynamic patterns of human immunodeficiency virus type 1 integrase gene evolution in patients failing raltegravir-based salvage therapies

scientific article

Effectiveness, durability, and safety of darunavir/ritonavir in HIV-1-infected patients in routine clinical practice in Italy: a postauthorization noninterventional study

scientific article published on 6 May 2016

Effects of atazanavir/ritonavir and lopinavir/ritonavir on glucose uptake and insulin sensitivity

scientific article

Efficacy and safety in clinical practice of a rilpivirine, tenofovir and emtricitabine single-tablet regimen in virologically suppressed HIV-positive patients on stable antiretroviral therapy

scientific article published on 30 July 2015

Efficacy and safety of a switch to unboosted atazanavir in combination with nucleoside analogues in HIV-1-infected patients with virological suppression under antiretroviral therapy

article

Efficacy and safety of switching from branded to generic antiretrovirals in virologically suppressed HIV-infected patients

scientific article published on August 2017

Efficacy of elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil fumarate as treatment for primary or recent HIV infection-authors' response

scientific article published on 14 March 2017

Efficacy of elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil fumarate as treatment for primary or recent HIV infection.

scientific article

Electrocardiographic changes in HIV-infected, drug-experienced patients being treated with atazanavir

article

Enfuvirtide (T-20) cross-reactive glycoprotein 41 antibody does not impair the efficacy or safety of enfuvirtide

scientific article published on 05 December 2003

Eosinophils from Physiology to Disease: A Comprehensive Review.

scientific article

Epstein-Barr virus DNA in cerebrospinal fluid from patients with AIDS-related primary lymphoma of the central nervous system.

scientific article published in August 1993

Estimated Glomerular Filtration Rate Trajectories in HIV-Infected Subjects Treated With Different Ritonavir-Boosted Protease Inhibitors and Tenofovir Disoproxil Fumarate or Abacavir

scientific article published on May 2016

Etravirine for the treatment of HIV infection.

scientific article published on August 2008

Etravirine plasma exposure is associated with virological efficacy in treatment-experienced HIV-positive patients.

scientific article published on 23 May 2014

Evolution of HIV-1 tropism at quasispecies level after 5 years of combination antiretroviral therapy in patients always suppressed or experiencing episodes of virological failure

scientific article published on 10 July 2014

Evolution of blood-associated HIV-1 DNA levels after 48 weeks of switching to atazanavir/ritonavir+lamivudine dual therapy versus continuing triple therapy in the randomized AtLaS-M trial

scientific article

Evolutionary Characteristics of HIV Type 1 Variants Resistant to Protease Inhibitors in the Absence of Drug-Selective Pressure

article

Ganciclovir Therapy for Cytomegalovirus (CMV) Infection of the Central Nervous System in AIDS Patients: Monitoring by CMV DNA Detection in Cerebrospinal Fluid

article

Genotype and phenotype patterns of human immunodeficiency virus type 1 resistance to enfuvirtide during long-term treatment

scientific article

Genotypic/phenotypic patterns of HIV-1 integrase resistance to raltegravir.

scientific article published on 7 January 2010

Glucose tolerance in HIV-1 treated patients who switched from boosted-protease inhibitors to etravirine

scientific article published in October 2013

HIV DNA loads, plasma residual viraemia and risk of virological rebound in heavily treated, virologically suppressed HIV-infected patients.

scientific article published on 13 October 2014

HIV protease inhibitors: present and future

article

HIV-1 replication capacity and genotype changes in patients undergoing treatment interruption or lamivudine monotherapy.

scientific article published in February 2008

High-density lipoprotein-cholesterol levels and risk of cancer in HIV-infected subjects: Data from the ICONA Foundation Cohort

scientific article

Higher plasma lopinavir concentrations are associated with a moderate rise in cholestasis markers in HIV-infected patients.

scientific article

Identification of TRIM22 single nucleotide polymorphisms associated with loss of inhibition of HIV-1 transcription and advanced HIV-1 disease

scientific article published on September 2013

Immortal time bias: authors' reply

scientific article published in April 2015

Immune activation and microbial translocation in liver disease progression in HIV/hepatitis co-infected patients: results from the Icona Foundation study

scientific article

Immune recovery and T cell subset analysis during effective treatment with maraviroc

scientific article published on 7 June 2012

Immune response to hepatitis B vaccination in HIV-positive individuals with isolated antibodies against hepatitis B core antigen: Results of a prospective Italian study.

scientific article published on September 2017

Immunological basis for IgE hyper-production in enfuvirtide-treated HIV- positive patients

scientific article published in March 2006

Impact of CD4 and CD8 dynamics and viral rebounds on loss of virological control in HIV controllers

scientific article published on 5 April 2017

Impact of a treatment including tenofovir plus didanosine on the selection of the 65R mutation in highly drug-experienced HIV-infected patients

scientific article published in November 2004

Impaired CD4 T-Cell Count Response to Combined Antiretroviral Therapy in Antiretroviral-Naive HIV-Infected Patients Presenting With Tuberculosis as AIDS-Defining Condition

scientific article published on 12 December 2011

Improved darunavir genotypic mutation score predicting treatment response for patients infected with HIV-1 subtype B and non-subtype B receiving a salvage regimen

scientific article published on 28 January 2016

In vitro phenotypes to elvitegravir and dolutegravir in primary macrophages and lymphocytes of clonal recombinant viral variants selected in patients failing raltegravir

scientific article published on 24 June 2013

Incidence, timing, and determinants of bacterial pneumonia among HIV-infected patients: data from the ICONA Foundation Cohort

scientific article

Inconsistent condom use among HIV-positive women in the "Treatment as Prevention Era": data from the Italian DIDI study

scientific article

Inhibition of HIV replication by the plasminogen activator is dependent on vitronectin-mediated cell adhesion

article

Integrase and fusion inhibitors transmitted drug resistance in naive patients with recent diagnosis of HIV-1 infection

scientific article published in February 2011

Is statin preventing cancer in HIV-1 infected individuals? An inappropriate methodology is a more likely explanation: authors' reply

scientific article published in April 2015

Italian consensus statement on management of HIV-infected individuals with advanced disease naïve to antiretroviral therapy.

scientific article published on 28 May 2009

Lamivudine monotherapy in HIV-1-infected patients harbouring a lamivudine-resistant virus: a randomized pilot study (E-184V study).

scientific article

Late presenters in new HIV diagnoses from an Italian cohort of HIV-infected patients: prevalence and clinical outcome

scientific article published on January 2011

Long-term CD4+ T-cell count evolution after switching from regimens including HIV nucleoside reverse transcriptase inhibitors (NRTI) plus protease inhibitors to regimens containing NRTI plus non-NRTI or only NRTI

scientific article

Long-term efficacy and safety of rilpivirine plus abacavir and lamivudine in HIV-1 infected patients with undetectable viral load

scientific article published on 16 February 2018

Long-term efficacy of dolutegravir in treatment-experienced subjects failing therapy with HIV-1 integrase strand inhibitor-resistant virus

scientific article published on 24 October 2017

Long-term glucose tolerance in highly experienced HIV-infected patients receiving nucleoside analogue-sparing regimens

scientific article published in September 2012

Long-term mortality in HIV-positive individuals virally suppressed for >3 years with incomplete CD4 recovery.

scientific article published on 22 January 2014

Long-term response in patients receiving HAART including nelfinavir: experience from two Italian centers.

scientific article

Longitudinal analysis of HIV-1 coreceptor tropism by single and triplicate HIV-1 RNA and DNA sequencing in patients undergoing successful first-line antiretroviral therapy

scientific article published on 23 October 2013

Longitudinal evaluation of occult Hepatitis B infection in HIV-1 infected individuals during highly active antiretroviral treatment interruption and after HAART resumption

article

Lopinavir/ritonavir treatment in HIV antiretroviral-experienced patients: evaluation of risk factors for liver enzyme elevation.

scientific article published on September 2004

Magnitude and determinants of CD4 recovery after HAART resumption after 1 cycle of treatment interruption

scientific article published in December 2009

Maraviroc is a substrate for OATP1B1 in vitro and maraviroc plasma concentrations are influenced by SLCO1B1 521 T>C polymorphism

scientific article published on December 2010

Mediator release in cerebrospinal fluid of human immunodeficiency virus-positive patients with central nervous system involvement

scientific article published on May 1, 1992

Microbial translocation predicts disease progression of HIV-infected antiretroviral-naive patients with high CD4+ cell count

article

Monotherapy With Atazanavir as a Simplificati Strategy

Mortality in patients with HIV-1 infection starting antiretroviral therapy in South Africa, Europe, or North America: a collaborative analysis of prospective studies

scientific article

Mortality of HIV-infected patients with or without cancer: comparison with the general population in Italy

scientific article published on 18 November 2011

No pol mutation is associated independently with the lack of immune recovery in patients infected with HIV and failing antiretroviral therapy

scientific article published on March 2011

Non-invasive fibrosis biomarkers - APRI and Forns - are associated with liver stiffness in HIV-monoinfected patients receiving antiretroviral drugs

scientific article published on 28 March 2013

Number of daily pills, dosing schedule, self-reported adherence and health status in 2010: a large cross-sectional study of HIV-infected patients on antiretroviral therapy.

scientific article published on 20 September 2012

Oligoclonal IgG bands in cerebrospinal fluid and serum during asymptomatic human immunodeficiency virus infection.

scientific article

Optimal dietary calcium intake in HIV treated patients: no femoral osteoporosis but higher cardiovascular risk

scientific article published on 12 July 2013

Osteoprotegerin and bone turnover markers in heavily pretreated HIV-infected patients.

scientific article published in May 2005

Pharmacokinetic and pharmacodynamic determinants of early virological response to enfuvirtide-based regimens in HIV-positive patients

scientific article

Pharmacokinetics of amprenavir given once or twice a day when combined with atazanavir in heavily pre-treated HIV-positive patients

scientific article published in December 2003

Pharmacokinetics of dolutegravir and rilpivirine in combination with simeprevir and sofosbuvir in HIV/hepatitis C virus-coinfected patients with liver cirrhosis

scientific article published on 20 December 2016

Pharmacokinetics of the raltegravir/maraviroc/etravirine combination

scientific article published on 04 June 2011

Pharmacokinetics of two randomized trials evaluating the safety and efficacy of indinavir, saquinavir and lopinavir in combination with low-dose ritonavir: the MaxCmin1 and 2 trials

scientific article published in November 2007

Pharmacotherapeutic management of HIV in transplant patients

scientific article published on 13 May 2019

Phase 2 double-blind, randomized trial of etravirine versus efavirenz in treatment-naive patients: 48-week results

scientific article published in November 2011

Plasma fibroblast growth factor 23 and osteocalcin serum levels are associated with cardiovascular risk in HIV-1-infected patients receiving antiretroviral treatment

scientific article published on 27 June 2013

Polyclonal serum-free light chains elevation in HIV-infected patients

article

Polymerase chain reaction for Toxoplasma gondii DNA in the cerebrospinal fluid of AIDS patients with focal brain lesions

Polymerase chain reaction on cerebrospinal fluid for diagnosis of virus-associated opportunistic diseases of the central nervous system in HIV-infected patients

scientific article published in August 1996

Predicting the magnitude of short-term CD4+ T-cell recovery in HIV-infected patients during first-line highly active antiretroviral therapy

scientific article published in January 2010

Predictors of sustained response to therapy resumption after treatment interruption in HIV-infected patients failing antiretroviral therapy

scientific article published in February 2004

Pregnancy outcomes among ART-naive and ART-experienced HIV-positive women: data from the ICONA foundation study group, years 1997-2013.

scientific article

Presence of multiple genotypes in subjects with HPV-16 infection is highly associated with anal squamous intraepithelial lesions in HIV-1 infected males

scientific article published on 31 October 2017

Prevalence, Associated Factors, and Prognostic Determinants of AIDS‐Related Toxoplasmic Encephalitis in the Era of Advanced Highly Active Antiretroviral Therapy

article

Prior Therapy Influences the Efficacy of Lamivudine Monotherapy in Patients With Lamivudine-Resistant HIV-1 Infection

article

Raltegravir, maraviroc, etravirine: an effective protease inhibitor and nucleoside reverse transcriptase inhibitor-sparing regimen for salvage therapy in HIV-infected patients with triple-class experience

scientific article published in March 2010

Randomized trial to evaluate indinavir/ritonavir versus saquinavir/ritonavir in human immunodeficiency virus type 1-infected patients: the MaxCmin1 Trial

scientific article published on 20 August 2003

Redistribution of human immunodeficiency virus type 1 variants resistant to protease inhibitors after a protease inhibitor-sparing regimen.

scientific article

Refining criteria for selecting candidates for a safe lopinavir/ritonavir or darunavir/ritonavir monotherapy in HIV-infected virologically suppressed patients

scientific article

Residual viraemia does not influence 1 year virological rebound in HIV-infected patients with HIV RNA persistently below 50 copies/mL

article

Risk factors and outcomes for late presentation for HIV-positive persons in Europe: results from the Collaboration of Observational HIV Epidemiological Research Europe Study (COHERE)

scientific article (publication date: 2013)

Risk of developing specific AIDS-defining illnesses in patients coinfected with HIV and hepatitis C virus with or without liver cirrhosis

scientific article published on August 2009

Risk of type 2 diabetes among HIV-infected and healthy subjects in Italy

scientific article

Role of brain biopsy in the management of focal brain lesions in HIV-infected patients

article

Simplification to a dual regimen with darunavir/ritonavir plus lamivudine or emtricitabine in virologically-suppressed HIV-infected patients

article

Simplification to atazanavir/ritonavir monotherapy for HIV-1 treated individuals on virological suppression: 48-week efficacy and safety results

scientific article

Stavudine or indinavir-containing regimens are associated with an increased risk of diabetes mellitus in HIV-infected individuals

scientific article published in September 2003

Steady-state pharmacokinetics of atazanavir given alone or in combination with saquinavir hard-gel capsules or amprenavir in HIV-1-infected patients

scientific article published on 23 July 2005

Stepping up HIV-1 low-level viraemia surveillance in South Africa

scientific article published on 17 November 2017

Survival and predictors of death in people with HIV-associated lymphoma compared to those with a diagnosis of lymphoma in general population.

scientific article published on 31 October 2017

Survival of HIV-1 infected multidrug-resistant patients recycling enfuvirtide after a previous failure

scientific article

Sustained HIV RNA suppression after switching from enfuvirtide to etravirine in the early access programme

scientific article published on 14 October 2009

Switch of predicted HIV-1 tropism in treated subjects and its association with disease progression

scientific article published on November 2016

Switching to unboosted atazanavir improves glucose tolerance in highly pretreated HIV-1 infected subjects

scientific article published on April 2007

Ten-year survival among HIV-1-infected subjects with AIDS or non-AIDS-defining malignancies

article

Thallium-201 Single Photon Emission Computed Tomography in the Management of Contrast-Enhancing Brain Lesions in a Patient with AIDS

article

The 118I reverse transcriptase mutation is the only independent genotypic predictor of virologic failure to a stavudine-containing salvage therapy in HIV-1-infected patients

scientific article published in April 2006

The appealing story of HIV entry inhibitors : from discovery of biological mechanisms to drug development

scientific article published in January 2005

The rate of accumulation of nonnucleoside reverse transcriptase inhibitor (NNRTI) resistance in patients kept on a virologically failing regimen containing an NNRTI*

scientific article published on 17 August 2011

The use of circulating cathodic antigen rapid test and serology for diagnosis of active Schistosoma mansoni infection in migrants in Italy, a non-endemic country: a cross sectional study

scientific article published on June 2017

Treatment simplification to atazanavir/ritonavir + lamivudine versus maintenance of atazanavir/ritonavir + two NRTIs in virologically suppressed HIV-1-infected patients: 48 week results from a randomized trial (ATLAS-M).

scientific article

Triglyceride/HDL ratio and its impact on the risk of diabetes mellitus development during ART.

scientific article published on 5 June 2016

Triple-class virologic failure in HIV-infected patients undergoing antiretroviral therapy for up to 10 years

scientific article published in March 2010

Unexpected dramatic increase in CD4+ cell count in a patient with AIDS after enfuvirtide treatment despite persistent viremia and resistance mutations

scientific article published on June 2008

Use of statins and risk of AIDS-defining and non-AIDS-defining malignancies among HIV-1 infected patients on antiretroviral therapy

scientific article

Viral rebound after switch to maraviroc/raltegravir dual therapy in highly experienced and virologically suppressed patients with HIV-1 infection

scientific article published on 23 January 2014

Viral tropism by geno2pheno as a tool for predicting CD4 decrease in HIV-1-infected naive patients with high CD4 counts

scientific article published on 31 January 2012

Viro-immunological dynamics in HIV-1-infected subjects receiving once-a-week emtricitabine to delay treatment change after failure: a pilot randomised trial

scientific article published on 6 January 2010

Virological rebound in human immunodeficiency virus-infected patients with or without residual viraemia: results from an extended follow-up.

scientific article published on 24 July 2013

Where is the greatest impact of uncontrolled HIV infection on AIDS and non-AIDS events in HIV?

scientific article published on 3 November 2017

Zidovudine and frequency of HIV-induced diffuse leukoencephalopathy

scientific article published on June 15, 1991