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List of works by Florence Margottin-Goguet

AT2 Receptor-Interacting Proteins ATIPs in the Brain.

scientific article

Assembly with the Cul4A-DDB1DCAF1 ubiquitin ligase protects HIV-1 Vpr from proteasomal degradation.

scientific article

Basal promoter and enhancer element of yeast U6 snRNA gene

scientific article published on 01 October 1993

Binding to DCAF1 distinguishes TASOR and SAMHD1 degradation by HIV-2 Vpx

scientific article published on 26 October 2021

Control of meiotic and mitotic progression by the F box protein beta-Trcp1 in vivo

scientific article (publication date: June 2003)

Emi1 regulates the anaphase-promoting complex by a different mechanism than Mad2 proteins ⬇️

scientific article published on December 15, 2001

Evidence that HIV-1 restriction factor SAMHD1 facilitates differentiation of myeloid THP-1 cells

scientific article published on 25 November 2015

FOXO1 transcription factor plays a key role in T cell-HIV-1 interaction.

scientific article published in May 2019

HIV-1 Vpr degrades the HLTF DNA translocase in T cells and macrophages

scientific article published on 25 April 2016

HIV-1 Vpr induces the degradation of ZIP and sZIP, adaptors of the NuRD chromatin remodeling complex, by hijacking DCAF1/VprBP.

scientific article

HIV-1 Vpr mediates the depletion of the cellular repressor CTIP2 to counteract viral gene silencing

scientific article published on 11 September 2019

HIV1 Vpr arrests the cell cycle by recruiting DCAF1/VprBP, a receptor of the Cul4-DDB1 ubiquitin ligase

scientific article published in August 2009

HUSH, a Link Between Intrinsic Immunity and HIV Latency

article

How SLX4 cuts through the mystery of HIV-1 Vpr-mediated cell cycle arrest.

scientific article

Human TRIM gene expression in response to interferons

scientific article

Inducible degradation of IkappaBalpha by the proteasome requires interaction with the F-box protein h-betaTrCP.

scientific article published in March 1999

Interaction between the Cytoplasmic Domains of HIV-1 Vpu and CD4: Role of Vpu Residues Involved in CD4 Interaction andin VitroCD4 Degradation

article

Interferon block to HIV-1 transduction in macrophages despite SAMHD1 degradation and high deoxynucleoside triphosphates supply ⬇️

scientific article published on March 11, 2013

Limelight on two HIV/SIV accessory proteins in macrophage infection: is Vpx overshadowing Vpr?

scientific article published on 09 April 2010

Molecular insight into how HIV-1 Vpr protein impairs cell growth through two genetically distinct pathways.

scientific article published on 12 May 2011

Noise from Vpx: "HUSH"!

scientific article published on 23 January 2019

Prophase destruction of Emi1 by the SCF(betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase

scientific article

RASSF1C, an Isoform of the Tumor Suppressor RASSF1A, Promotes the Accumulation of β-Catenin by Interacting with βTrCP

scientific article published on 01 February 2007

RNR2 repression by p21 restricts reverse transcription of HIV-1 and related-lentiviruses in macrophages.

scientific article published on 19 September 2013

Regulated degradation of the HIV-1 Vpu protein through a betaTrCP-independent pathway limits the release of viral particles

scientific article

Reply to Pauls et al.: p21 is a master regulator of HIV replication in macrophages through dNTP synthesis block

scientific article published on April 2014

SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates

scientific article

Specific Inhibition of HIV Infection by the Action of Spironolactone in T Cells.

scientific article published on 28 September 2016

The F-box protein beta-TrCP associates with phosphorylated beta-catenin and regulates its activity in the cell.

scientific article published on February 1999

The human immunodeficiency virus type 2 Vpx protein usurps the CUL4A-DDB1 DCAF1 ubiquitin ligase to overcome a postentry block in macrophage infection

scientific article

Vpu antagonizes BST-2-mediated restriction of HIV-1 release via beta-TrCP and endo-lysosomal trafficking

scientific article

p21-mediated RNR2 repression restricts HIV-1 replication in macrophages by inhibiting dNTP biosynthesis pathway

scientific article published on 30 September 2013

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