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List of works by Giovanni Sitia

42. Correction of SCID-X1 by Targeted Genome Editing of Hematopoietic Stem/Progenitor Cells (HSPC) in the Mouse Model

scholarly article by Giulia Schiroli published in May 2016

481. Targeted Genome Editing in Mouse Hematopoietic Stem/Progenitor Cells (HSPC) To Model Gene Correction of SCID-X1

article

5 INVITED Role of haematopoietic cells in tumour angiogenesis: from discovery to targeted cancer gene therapy

article

79. Systemic Administration of Lentiviral Vectors Triggers Innate Host Responses

article

A novel role for HMGB1 in TLR9-mediated inflammatory responses to CpG-DNA.

scientific article

AAV6-mediated systemic shRNA delivery reverses disease in a mouse model of facioscapulohumeral muscular dystrophy

scientific article published on 9 August 2011

Acute self-limiting hepatitis C after possible sexual exposure: sequence analysis of the E-2 region of the infected patient and sexual partner.

scientific article published in January 2001

Anti-platelet therapy in the prevention of hepatitis B virus-associated hepatocellular carcinoma ⬇️

scientific article published on June 4, 2013

Antiplatelet drug therapy moderates immune-mediated liver disease and inhibits viral clearance in mice infected with a replication-deficient adenovirus

scientific article (publication date: November 2007)

Antiplatelet therapy prevents hepatocellular carcinoma and improves survival in a mouse model of chronic hepatitis B.

scientific article

Bisphosphonates target B cells to enhance humoral immune responses

scientific article published on 10 October 2013

Bone marrow as an alternative site for islet transplantation.

scientific article published on 22 September 2009

Chronic hepatitis B: role of anti-platelet therapy in inflammation control

scientific article published on 12 January 2015

Defective Th1 cytokine gene transcription in CD4+ and CD8+ T cells from Wiskott-Aldrich syndrome patients.

scientific article published on November 2006

Depletion of neutrophils blocks the recruitment of antigen-nonspecific cells into the liver without affecting the antiviral activity of hepatitis B virus-specific cytotoxic T lymphocytes

scientific article

HBV pathogenesis in animal models: recent advances on the role of platelets

scientific article

High mobility group box 1 orchestrates tissue regeneration via CXCR4.

scientific article published on 4 December 2017

IFNα gene/cell therapy curbs colorectal cancer colonization of the liver by acting on the hepatic microenvironment

scientific article published on 14 January 2016

Immunosurveillance of the liver by intravascular effector CD8(+) T cells.

scientific article published on 16 April 2015

In vivo administration of lentiviral vectors triggers a type I interferon response that restricts hepatocyte gene transfer and promotes vector clearance.

scientific article published in April 2007

Kupffer cells hasten resolution of liver immunopathology in mouse models of viral hepatitis

scientific article (publication date: June 2011)

Liver fibrosis in HIV-positive patients with hepatitis C virus: role of persistently normal alanine aminotransferase levels

scientific article

MMPs are required for recruitment of antigen-nonspecific mononuclear cells into the liver by CTLs.

scientific article published on April 2004

Mother-to-child transmission of TT virus: sequence analysis of non-coding region of TT virus in infected mother-infant pairs.

scientific article published on April 2002

New players in non-alcoholic fatty liver disease induced carcinogenesis: lipid dysregulation impairs liver immune surveillance

scientific article published on December 2016

Nkx2-5(+)islet1(+) mesenchymal precursors generate distinct spleen stromal cell subsets and participate in restoring stromal network integrity

scientific article published on April 2013

On the role of platelets in the pathogenesis of viral hepatitis

scientific article published on 21 May 2009

On the use of superparamagnetic hydroxyapatite nanoparticles as an agent for magnetic and nuclear in vivo imaging

scientific article published on 21 April 2018

Pathogenetic and antiviral immune responses against hepatitis B virus

article

Platelets mediate cytotoxic T lymphocyte-induced liver damage

scientific article

Platelets prevent IFN-alpha/beta-induced lethal hemorrhage promoting CTL-dependent clearance of lymphocytic choriomeningitis virus.

scientific article

Platelets promote liver immunopathology contributing to hepatitis B virus-mediated hepatocarcinogenesis

scientific article published on 24 April 2014

Preclinical modeling highlights the therapeutic potential of hematopoietic stem cell gene editing for correction of SCID-X1.

scientific article published in October 2017

Rapamycin-sensitive signals control TCR/CD28-driven Ifng, Il4 and Foxp3 transcription and promoter region methylation

scientific article

Reduced severity of liver ischemia/reperfusion injury following hepatic resection in humans is associated with enhanced intrahepatic expression of Th2 cytokines

scientific article published on 10 July 2006

Ribavirin therapy for chronic hepatitis C does not modify HIV viral load in HIV-1 positive patients under antiretroviral treatment.

scientific article

Role of CCL2/MCP-1 in islet transplantation

scientific article published on 11 June 2010

The COP9 signalosome is a repressor of replicative stress responses and polyploidization in the regenerating liver

article

Towards personalized medicine in chronic HBV patients?

scientific article published on 01 July 2015

Treatment with HMGB1 inhibitors diminishes CTL-induced liver disease in HBV transgenic mice

scientific article

Tumor-targeted interferon-alpha delivery by Tie2-expressing monocytes inhibits tumor growth and metastasis

scientific article published on October 2008

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