List of works - Sandra Macedo-Ribeiro

A tale of a tail: Structural insights into the conformational properties of the polyglutamine protein ataxin-3. ⬇️

scientific article published on July 2013

Anti-TTR Nanobodies Allow the Identification of TTR Neuritogenic Epitope Associated with TTR-Megalin Neurotrophic Activities

Ataxin-3 phosphorylation decreases neuronal defects in spinocerebellar ataxia type 3 models

scientific article published on February 2016

Ataxin-3 plays a role in mouse myogenic differentiation through regulation of integrin subunit levels

scientific article

Biochemical and biophysical characterization of recombinant yeast proteasome maturation factor ump1.

scientific article

Biophysical characterization of laforin-carbohydrate interaction.

scientific article published on 17 November 2015

Biosynthesis of mycobacterial methylmannose polysaccharides requires a unique 1--methyltransferase specific for 3--methylated mannosides

article published in the Proceedings of the National Academy of Sciences of the United States of America

CLASP2 binding to curved microtubule tips promotes flux and stabilizes kinetochore attachments

scientific article published on 01 February 2020

Cdk1 and Plk1 mediate a CLASP2 phospho-switch that stabilizes kinetochore-microtubule attachments

scientific article

Chemical Kinetic Strategies for High-Throughput Screening of Protein Aggregation Modulators

scientific article published on 01 February 2019

Cloning, purification and preliminary crystallographic studies of the 2AB protein from hepatitis A virus

scientific article published on 29 September 2011

Crystal structure of a novel cysteinless plant Kunitz-type protease inhibitor

scientific article

Crystal structures of the membrane-binding C2 domain of human coagulation factor V

scientific article

Crystallization and preliminary crystallographic analysis of mannosyl-3-phosphoglycerate synthase from Rubrobacter xylanophilus

scientific article published on 31 July 2008

DisProt 7.0: a major update of the database of disordered proteins.

scientific article

DisProt: intrinsic protein disorder annotation in 2020

scientific article published on 01 January 2020

Disclosing the essentiality of ribose-5-phosphate isomerase B in Trypanosomatids

scientific article published on 27 May 2016

Distribution of Amyloid-Like and Oligomeric Species from Protein Aggregation Kinetics

scientific article

Examination of Ataxin-3 (atx-3) Aggregation by Structural Mass Spectrometry Techniques: A Rationale for Expedited Aggregation upon Polyglutamine (polyQ) Expansion ⬇️

scientific article

Functional and structural characterization of a novel mannosyl‐3‐phosphoglycerate synthase from Rubrobacter xylanophilus reveals its dual substrate specificity ⬇️

scientific article published on November 2, 2010

Genetic code ambiguity modulates the activity of a C. albicans MAP kinase linked to cell wall remodeling

scientific article published on 20 February 2019

Genome sequence of Mycobacterium hassiacum DSM 44199, a rare source of heat-stable mycobacterial proteins.

scientific article published on December 2012

Heterologous Expression of the Vanadium-containing Chloroperoxidase fromCurvularia inaequalisinSaccharomyces cerevisiaeand Site-directed Mutagenesis of the Active Site Residues His496, Lys353, Arg360, and Arg490

scientific article published in Journal of Biological Chemistry

Human beta-tryptase is a ring-like tetramer with active sites facing a central pore

scientific article

Human transthyretin in complex with iododiflunisal: structural features associated with a potent amyloid inhibitor

scientific article published on June 2005

Identification of the mycobacterial glucosyl-3-phosphoglycerate synthase

scientific journal article

Isolation, Cloning and Structural Characterisation of Boophilin, a Multifunctional Kunitz-Type Proteinase Inhibitor from the Cattle Tick

scientific article

Leech-derived thrombin inhibitors: from structures to mechanisms to clinical applications

scientific article published on May 2010

Leishmania infantum Asparagine Synthetase A Is Dispensable for Parasites Survival and Infectivity

scientific article

Lysosomal multienzymatic complex-related diseases: a genetic study among Portuguese patients

article

Molecular Fingerprints for a Novel Enzyme Family in with Glucosamine Kinase Activity

scientific article published on 14 May 2019

Molecular and computational analyses of genes involved in mannose 6-phosphate independent trafficking

article

Molecular and structural analyses of maple syrup urine disease and identification of a founder mutation in a Portuguese Gypsy community

scientific article

Molecular fingerprints for a novel glucosamine kinase family in Actinobacteria:

Molecular motion regulates the activity of the Mitochondrial Serine Protease HtrA2.

scientific article published on 12 October 2017

Mycobacterium tuberculosis glucosyl-3-phosphoglycerate synthase: structure of a key enzyme in methylglucose lipopolysaccharide biosynthesis

scientific article

NEDD8: A new ataxin-3 interactor

scientific article published on 24 August 2007

New insights into the thermostability of bacterial ferredoxins: high-resolution crystal structure of the seven-iron ferredoxin from Thermus thermophilus

scientific article

Nucleocytoplasmic shuttling activity of ataxin-3.

scientific article

Octanoylation of early intermediates of mycobacterial methylglucose lipopolysaccharides

scientific journal article

Polyglutamine expansion diseases: More than simple repeats

scientific article published on 16 September 2017

Polyglutamine-Independent Features in Ataxin-3 Aggregation and Pathogenesis of Machado-Joseph Disease.

scientific article published in January 2018

Probing the Occurrence of Soluble Oligomers through Amyloid Aggregation Scaling Laws

scientific article published on 04 October 2018

Protein crystals as a key for deciphering macromolecular crowding effects on biological reactions

scientific article published on 08 July 2020

Purification, crystallization and preliminary X-ray diffraction analysis of the seryl-tRNA synthetase from Candida albicans

scientific article published on 24 December 2010

Ribose 5-phosphate isomerase B knockdown compromises Trypanosoma brucei bloodstream form infectivity

scientific article

SUMOylation of the brain-predominant Ataxin-3 isoform modulates its interaction with p97.

scientific article published on 11 June 2015

Ser or Leu: structural snapshots of mistranslation in Candida albicans.

scientific article published on 19 December 2014

Severe neonatal jaundice due to ade novoglucose-6-phosphate dehydrogenase deficient mutation

scientific article published on 23 December 2015

Small structural changes account for the high thermostability of 1[4Fe-4S] ferredoxin from the hyperthermophilic bacterium Thermotoga maritima

scientific article

Structural basis for host membrane remodeling induced by protein 2B of hepatitis A virus

scientific article

Structural basis for stereo-specific catalysis in NAD(+)-dependent (R)-2-hydroxyglutarate dehydrogenase from Acidaminococcus fermentans

scientific article published in January 2005

Structure of human biliverdin IXbeta reductase, an early fetal bilirubin IXbeta producing enzyme

scientific article

Structure of mycobacterial maltokinase, the missing link in the essential GlgE-pathway

scientific article (publication date: 26 January 2015)

The Drosophila melanogaster methuselah gene: a novel gene with ancient functions

scientific article

The apoptogenic toxin AIP56 is a metalloprotease A-B toxin that cleaves NF-κb P65

scientific article

The structural characterization of a glucosylglycerate hydrolase provides insights into the molecular mechanism of mycobacterial recovery from nitrogen starvation

scientific article published on 08 May 2019

The unique regulation of iron-sulfur cluster biogenesis in a Gram-positive bacterium

scientific article

Tick-derived Kunitz-type inhibitors as antihemostatic factors

scientific article published on 24 July 2009

Towards a structural understanding of the fibrillization pathway in Machado-Joseph's disease: trapping early oligomers of non-expanded ataxin-3.

scientific article

Trinucleotide repeats: a structural perspective

scientific article

Trypanosoma cruzi macrophage infectivity potentiator has a rotamase core and a highly exposed alpha-helix

scientific article

Unique thrombin inhibition mechanism by anophelin, an anticoagulant from the malaria vector

scientific article

Unveiling the structural basis for translational ambiguity tolerance in a human fungal pathogen

scientific article

What a difference a cluster makes: The multifaceted roles of IscR in gene regulation and DNA recognition

scientific article

X-ray crystal structures of active site mutants of the vanadium-containing chloroperoxidase from the fungus Curvularia inaequalis

scientific article

List of works by Sandra Macedo-Ribeiro

A tale of a tail: Structural insights into the conformational properties of the polyglutamine protein ataxin-3. ⬇️

Anti-TTR Nanobodies Allow the Identification of TTR Neuritogenic Epitope Associated with TTR-Megalin Neurotrophic Activities

Ataxin-3 phosphorylation decreases neuronal defects in spinocerebellar ataxia type 3 models

Ataxin-3 plays a role in mouse myogenic differentiation through regulation of integrin subunit levels

Biochemical and biophysical characterization of recombinant yeast proteasome maturation factor ump1.

Biophysical characterization of laforin-carbohydrate interaction.

Biosynthesis of mycobacterial methylmannose polysaccharides requires a unique 1--methyltransferase specific for 3--methylated mannosides

CLASP2 binding to curved microtubule tips promotes flux and stabilizes kinetochore attachments

Cdk1 and Plk1 mediate a CLASP2 phospho-switch that stabilizes kinetochore-microtubule attachments

Chemical Kinetic Strategies for High-Throughput Screening of Protein Aggregation Modulators

Cloning, purification and preliminary crystallographic studies of the 2AB protein from hepatitis A virus

Crystal structure of a novel cysteinless plant Kunitz-type protease inhibitor

Crystal structures of the membrane-binding C2 domain of human coagulation factor V

Crystallization and preliminary crystallographic analysis of mannosyl-3-phosphoglycerate synthase from Rubrobacter xylanophilus

DisProt 7.0: a major update of the database of disordered proteins.

DisProt: intrinsic protein disorder annotation in 2020

Disclosing the essentiality of ribose-5-phosphate isomerase B in Trypanosomatids

Distribution of Amyloid-Like and Oligomeric Species from Protein Aggregation Kinetics

Examination of Ataxin-3 (atx-3) Aggregation by Structural Mass Spectrometry Techniques: A Rationale for Expedited Aggregation upon Polyglutamine (polyQ) Expansion ⬇️

Functional and structural characterization of a novel mannosyl‐3‐phosphoglycerate synthase from Rubrobacter xylanophilus reveals its dual substrate specificity ⬇️

Genetic code ambiguity modulates the activity of a C. albicans MAP kinase linked to cell wall remodeling

Genome sequence of Mycobacterium hassiacum DSM 44199, a rare source of heat-stable mycobacterial proteins.

Heterologous Expression of the Vanadium-containing Chloroperoxidase fromCurvularia inaequalisinSaccharomyces cerevisiaeand Site-directed Mutagenesis of the Active Site Residues His496, Lys353, Arg360, and Arg490

Human beta-tryptase is a ring-like tetramer with active sites facing a central pore

Human transthyretin in complex with iododiflunisal: structural features associated with a potent amyloid inhibitor

Identification of the mycobacterial glucosyl-3-phosphoglycerate synthase

Isolation, Cloning and Structural Characterisation of Boophilin, a Multifunctional Kunitz-Type Proteinase Inhibitor from the Cattle Tick

Leech-derived thrombin inhibitors: from structures to mechanisms to clinical applications

Leishmania infantum Asparagine Synthetase A Is Dispensable for Parasites Survival and Infectivity

Lysosomal multienzymatic complex-related diseases: a genetic study among Portuguese patients

Molecular Fingerprints for a Novel Enzyme Family in with Glucosamine Kinase Activity

Molecular and computational analyses of genes involved in mannose 6-phosphate independent trafficking

Molecular and structural analyses of maple syrup urine disease and identification of a founder mutation in a Portuguese Gypsy community

Molecular fingerprints for a novel glucosamine kinase family in Actinobacteria:

Molecular motion regulates the activity of the Mitochondrial Serine Protease HtrA2.

Mycobacterium tuberculosis glucosyl-3-phosphoglycerate synthase: structure of a key enzyme in methylglucose lipopolysaccharide biosynthesis

NEDD8: A new ataxin-3 interactor

New insights into the thermostability of bacterial ferredoxins: high-resolution crystal structure of the seven-iron ferredoxin from Thermus thermophilus

Nucleocytoplasmic shuttling activity of ataxin-3.

Octanoylation of early intermediates of mycobacterial methylglucose lipopolysaccharides

Polyglutamine expansion diseases: More than simple repeats

Polyglutamine-Independent Features in Ataxin-3 Aggregation and Pathogenesis of Machado-Joseph Disease.

Probing the Occurrence of Soluble Oligomers through Amyloid Aggregation Scaling Laws

Protein crystals as a key for deciphering macromolecular crowding effects on biological reactions

Purification, crystallization and preliminary X-ray diffraction analysis of the seryl-tRNA synthetase from Candida albicans

Ribose 5-phosphate isomerase B knockdown compromises Trypanosoma brucei bloodstream form infectivity

SUMOylation of the brain-predominant Ataxin-3 isoform modulates its interaction with p97.

Ser or Leu: structural snapshots of mistranslation in Candida albicans.

Severe neonatal jaundice due to ade novoglucose-6-phosphate dehydrogenase deficient mutation

Small structural changes account for the high thermostability of 1[4Fe-4S] ferredoxin from the hyperthermophilic bacterium Thermotoga maritima

Structural basis for host membrane remodeling induced by protein 2B of hepatitis A virus

Structural basis for stereo-specific catalysis in NAD(+)-dependent (R)-2-hydroxyglutarate dehydrogenase from Acidaminococcus fermentans

Structure of human biliverdin IXbeta reductase, an early fetal bilirubin IXbeta producing enzyme

Structure of mycobacterial maltokinase, the missing link in the essential GlgE-pathway

The Drosophila melanogaster methuselah gene: a novel gene with ancient functions

The apoptogenic toxin AIP56 is a metalloprotease A-B toxin that cleaves NF-κb P65

The structural characterization of a glucosylglycerate hydrolase provides insights into the molecular mechanism of mycobacterial recovery from nitrogen starvation

The unique regulation of iron-sulfur cluster biogenesis in a Gram-positive bacterium

Tick-derived Kunitz-type inhibitors as antihemostatic factors

Towards a structural understanding of the fibrillization pathway in Machado-Joseph's disease: trapping early oligomers of non-expanded ataxin-3.

Trinucleotide repeats: a structural perspective

Trypanosoma cruzi macrophage infectivity potentiator has a rotamase core and a highly exposed alpha-helix

Unique thrombin inhibition mechanism by anophelin, an anticoagulant from the malaria vector

Unveiling the structural basis for translational ambiguity tolerance in a human fungal pathogen

What a difference a cluster makes: The multifaceted roles of IscR in gene regulation and DNA recognition

X-ray crystal structures of active site mutants of the vanadium-containing chloroperoxidase from the fungus Curvularia inaequalis

X-ray crystallographic studies of two transthyretin variants: further insights into amyloidogenesis