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List of works by Melissa Bowerman

A Single Amino Acid Residue Regulates PTEN-Binding and Stability of the Spinal Muscular Atrophy Protein SMN

scientific article published on 03 November 2020

A critical smn threshold in mice dictates onset of an intermediate spinal muscular atrophy phenotype associated with a distinct neuromuscular junction pathology.

scientific article published on 8 November 2011

Defects in pancreatic development and glucose metabolism in SMN-depleted mice independent of canonical spinal muscular atrophy neuromuscular pathology.

scientific article

Expression of ALS-linked SOD1 Mutation in Motoneurons or Myotubes Induces Differential Effects on Neuromuscular Function In vitro

scientific article published on 29 March 2020

Fasudil improves survival and promotes skeletal muscle development in a mouse model of spinal muscular atrophy

scientific article

Funding for spinal muscular atrophy research must continue

scientific article published on 05 June 2019

Glucose metabolism and pancreatic defects in spinal muscular atrophy

scientific article

Interventions Targeting Glucocorticoid-Krüppel-like Factor 15-Branched-Chain Amino Acid Signaling Improve Disease Phenotypes in Spinal Muscular Atrophy Mice.

scientific article

KCC3 loss-of-function contributes to Andermann syndrome by inducing activity-dependent neuromuscular junction defects

article

Light modulation ameliorates expression of circadian genes and disease progression in spinal muscular atrophy mice

article

Multi-Study Proteomic and Bioinformatic Identification of Molecular Overlap between Amyotrophic Lateral Sclerosis (ALS) and Spinal Muscular Atrophy (SMA)

Muscle overexpression of Klf15 via an AAV8-Spc5-12 construct does not provide benefits in spinal muscular atrophy mice

scientific article published on 20 April 2020

Nerve injury induces a Gem-GTPase-dependent downregulation of P/Q-type Ca2+ channels contributing to neurite plasticity in dorsal root ganglion neurons

scientific article published on 09 May 2014

Neuroimmunity dynamics and the development of therapeutic strategies for amyotrophic lateral sclerosis

scientific article

Pathogenic commonalities between spinal muscular atrophy and amyotrophic lateral sclerosis: Converging roads to therapeutic development.

scientific article published on 4 December 2017

ROCK inhibition as a therapy for spinal muscular atrophy: understanding the repercussions on multiple cellular targets

scientific article

Recent Advances and Future Perspectives in the Development of Therapeutic Approaches for Neurodegenerative Diseases

scientific article published on 11 September 2020

Regulation of neuronal high-voltage activated Ca(V)2 Ca(2+) channels by the small GTPase RhoA.

scientific article published on 2 June 2015

SMN, profilin IIa and plastin 3: a link between the deregulation of actin dynamics and SMA pathogenesis.

scientific article

Smn depletion alters profilin II expression and leads to upregulation of the RhoA/ROCK pathway and defects in neuronal integrity

scientific article published on 01 January 2007

Somatic and axonal LIGHT signaling elicit degenerative and regenerative responses in motoneurons, respectively

scientific article

Spinal muscular atrophy: antisense oligonucleotide therapy opens the door to an integrated therapeutic landscape.

scientific article published in October 2017

Systemic peptide-mediated oligonucleotide therapy improves long-term survival in spinal muscular atrophy

scientific article

Therapeutic strategies for spinal muscular atrophy: SMN and beyond.

scientific article published on August 2017

Tweak regulates astrogliosis, microgliosis and skeletal muscle atrophy in a mouse model of amyotrophic lateral sclerosis.

scientific article published on 12 March 2015

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