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List of works by Raj K S Badhan

A dynamic perfusion based blood-brain barrier model for cytotoxicity testing and drug permeation

scientific article published on 02 March 2020

Application of Pharmacokinetics Modelling to Predict Human Exposure of a Cationic Liposomal Subunit Antigen Vaccine System.

scientific article published on 7 December 2017

Clopidogrel Pharmacokinetics in Malaysian Population Groups: The Impact of Inter-Ethnic Variability.

scientific article published on 26 July 2018

Design of Experiments to Study the Impact of Process Parameters on Droplet Size and Development of Non-Invasive Imaging Techniques in Tablet Coating

scientific article

Development and Evaluation of a Novel Intranasal Spray for the Delivery of Amantadine.

scientific article published on 30 January 2016

Development of a Region-Specific Physiologically Based Pharmacokinetic Brain Model to Assess Hippocampus and Frontal Cortex Pharmacokinetics.

scientific article published on 17 January 2018

Development of a paediatric physiologically based pharmacokinetic model to assess the impact of drug-drug interactions in tuberculosis co-infected malaria subjects: A case study with artemether-lumefantrine and the CYP3A4-inducer rifampicin

scientific article

Development of a physiologically-based pharmacokinetic model of the rat central nervous system.

scientific article published on 18 March 2014

Dose optimisation of chloroquine by pharmacokinetic modelling during pregnancy for the treatment of Zika virus infection

scientific article

Drug dosing during pregnancy-opportunities for physiologically based pharmacokinetic models

scientific article published on 26 June 2020

Fixed-dose combination orally disintegrating tablets to treat cardiovascular disease: formulation, in vitro characterization and physiologically based pharmacokinetic modeling to assess bioavailability.

scientific article published on 16 March 2017

High-throughput screening of excipients with a biological effect: a kinetic study on the effects of surfactants on efflux-mediated transport

scientific article published on 19 February 2019

Identification of putative steroid-binding sites in human ABCB1 and ABCG2.

scientific article published on 6 March 2009

Improving brain drug targeting through exploitation of the nose-to-brain route: a physiological and pharmacokinetic perspective.

scientific article published on January 2014

In silico modelling of the interaction of flavonoids with human P-glycoprotein nucleotide-binding domain.

scientific article published on 21 February 2006

Intracellular uptake of EGCG-loaded deformable controlled release liposomes for skin cancer

scientific article published on 22 April 2019

Methodology for development of a physiological model incorporating CYP3A and P-glycoprotein for the prediction of intestinal drug absorption

scientific article published in June 2009

Phytochemical mediated-modulation of the expression and transporter function of breast cancer resistance protein at the blood-brain barrier: An in-vitro study.

scientific article published on 19 October 2016

Phytochemical-loaded mesoporous silica nanoparticles for nose-to-brain olfactory drug delivery.

scientific article published on 12 September 2016

Phytoestrogens Modulate Breast Cancer Resistance Protein Expression and Function at the Blood-Cerebrospinal Fluid Barrier

scientific article published on April 2015

Precision dosing-based optimisation of paroxetine during pregnancy for poor and ultrarapid CYP2D6 metabolisers: a virtual clinical trial pharmacokinetics study

scientific article published on 28 April 2020

Quetiapine dose optimisation during gestation: a pharmacokinetic modelling study

scientific article published on 03 February 2020

The Repurposing of Ivermectin for Malaria: A Prospective Pharmacokinetics-Based Virtual Clinical Trials Assessment of Dosing Regimen Options.

scientific article

The application of physiologically-based pharmacokinetic modelling to assess the impact of antiretroviral-mediated drug-drug interactions on piperaquine antimalarial therapy during pregnancy

scientific article published on 14 July 2017

The impact of CYP2B6 polymorphisms on the interactions of efavirenz with lumefantrine: Implications for paediatric antimalarial therapy

The impact of ageing on the barriers to drug delivery.

scientific article published on 24 January 2012

The optimization of methadone dosing whilst treating with rifampicin: A pharmacokinetic modeling study

scientific article published on 20 May 2019

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