Search filters

List of works by Christopher P Wardell

A TC classification-based predictor for multiple myeloma using multiplexed real-time quantitative PCR.

scientific article

A high-risk, Double-Hit, group of newly diagnosed myeloma identified by genomic analysis

scientific article published in January 2019

A modified method for whole exome resequencing from minimal amounts of starting DNA

scientific article

A molecular diagnostic approach able to detect the recurrent genetic prognostic factors typical of presenting myeloma

scientific article

A novel functional role for MMSET in RNA processing based on the link between the REIIBP isoform and its interaction with the SMN complex

scientific article

A novel prognostic model in myeloma based on co-segregating adverse FISH lesions and the ISS: analysis of patients treated in the MRC Myeloma IX trial.

scientific article

APOBEC family mutational signatures are associated with poor prognosis translocations in multiple myeloma ⬇️

scientific article

Aberrant global methylation patterns affect the molecular pathogenesis and prognosis of multiple myeloma

scientific article published on 13 October 2010

BRAF and DIS3 Mutations Associate with Adverse Outcome in a Long-term Follow-up of Patients with Multiple Myeloma

scientific article published on 27 January 2020

Cancer whole-genome sequencing: present and future.

scientific article published on 30 March 2015

Characterization of IGH locus breakpoints in multiple myeloma indicates a subset of translocations appear to occur in pregerminal center B cells.

scientific article published on 22 February 2013

Cleavage of BLOC1S1 mRNA by IRE1 Is Sequence Specific, Temporally Separate from XBP1 Splicing, and Dispensable for Cell Viability under Acute Endoplasmic Reticulum Stress

scientific article published on 13 April 2015

Coexistent hyperdiploidy does not abrogate poor prognosis in myeloma with adverse cytogenetics and may precede IGH translocations

scientific article

Daratumumab and dexamethasone is safe and effective for triple refractory myeloma patients: final results of the IFM 2014-04 (Etoile du Nord) trial

scientific article published on 19 June 2019

Erratum: Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer

scientific article published on 01 May 2016

Gender disparities in the tumor genetics and clinical outcome of multiple myeloma

scientific article

Genetic Predisposition to Multiple Myeloma at 5q15 Is Mediated by an ELL2 Enhancer Polymorphism

scientific article published on September 2017

Genomewide profiling of copy-number alteration in monoclonal gammopathy of undetermined significance

scientific article published on 9 May 2016

Genomic Characterization of Biliary Tract Cancers Identifies Driver Genes and Predisposing Mutations.

scientific article published on 19 January 2018

Genomic analysis of primary plasma cell leukemia reveals complex structural alterations and high-risk mutational patterns

scientific article published on 19 June 2020

Global methylation analysis identifies prognostically important epigenetically inactivated tumor suppressor genes in multiple myeloma.

scientific article published on 22 May 2013

HSF1 Is Essential for Myeloma Cell Survival and A Promising Therapeutic Target.

scientific article

High expression levels of the mammalian target of rapamycin inhibitor DEPTOR are predictive of response to thalidomide in myeloma.

scientific article published on 21 September 2010

Identification of a novel t(7;14) translocation in multiple myeloma resulting in overexpression of EGFR.

scientific article published on 13 June 2013

Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma

scientific article published on 08 June 2018

Improved risk stratification in myeloma using a microRNA-based classifier.

scientific article published on 30 May 2013

Intraclonal heterogeneity and distinct molecular mechanisms characterize the development of t(4;14) and t(11;14) myeloma.

scientific article

Intraclonal heterogeneity is a critical early event in the development of myeloma and precedes the development of clinical symptoms

scientific article published on 02 July 2013

Mapping of chromosome 1p deletions in myeloma identifies FAM46C at 1p12 and CDKN2C at 1p32.3 as being genes in regions associated with adverse survival.

scientific article

Microhomology-mediated end joining drives complex rearrangements and over expression of MYC and PVT1 in multiple myeloma: Supplementary Data

scientific article published on 10 January 2019

Mutational Spectrum, Copy Number Changes, and Outcome: Results of a Sequencing Study of Patients With Newly Diagnosed Myeloma.

scientific article published on 17 August 2015

Neutral tumor evolution in myeloma is associated with poor prognosis. ⬇️

scientific article published on 21 August 2017

Proof of the concept to use a malignant B cell line drug screen strategy for identification and weight of melphalan resistance genes in multiple myeloma

scientific article (publication date: 2013)

Single-cell genetic analysis reveals the composition of initiating clones and phylogenetic patterns of branching and parallel evolution in myeloma

article

Spatial genomic heterogeneity in multiple myeloma revealed by multi-region sequencing

scientific article published on 16 August 2017

TCF12 is mutated in anaplastic oligodendroglioma

scientific article published on 12 June 2015

The Spectrum and Clinical Impact of Epigenetic Modifier Mutations in Myeloma. ⬇️

scientific article published on 27 May 2016

The clinical impact and molecular biology of del(17p) in multiple myeloma treated with conventional or thalidomide-based therapy

scientific article published on 11 July 2011

The genomic landscape of plasma cells in systemic light chain amyloidosis

scientific article published on 16 November 2018

The spectrum of somatic mutations in monoclonal gammopathy of undetermined significance indicates a less complex genomic landscape than that in multiple myeloma

scientific article published on 26 May 2017

Translocations at 8q24 juxtapose MYC with genes that harbor superenhancers resulting in overexpression and poor prognosis in myeloma patients

scientific article

Whole genome sequencing discriminates hepatocellular carcinoma with intrahepatic metastasis from multi-centric tumors

scientific article

Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer.

scientific article published on 11 April 2016

Paulina is supported by:

About Paulina

Help