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List of works by Charlotte Pawlyn

A novel functional role for MMSET in RNA processing based on the link between the REIIBP isoform and its interaction with the SMN complex

scientific article

APOBEC family mutational signatures are associated with poor prognosis translocations in multiple myeloma ⬇️

scientific article

Biologically defined risk groups can be used to define the impact of thalidomide maintenance therapy in newly diagnosed multiple myeloma.

scientific article published on 23 January 2013

Coexistent hyperdiploidy does not abrogate poor prognosis in myeloma with adverse cytogenetics and may precede IGH translocations

scientific article

Crystalline keratopathy associated with monoclonal gammopathy of undetermined significance

scientific article published on 07 September 2012

Current and potential epigenetic targets in multiple myeloma.

scientific article published on April 2014

Early relapse after high-dose melphalan autologous stem cell transplant predicts inferior survival and is associated with high disease burden and genetically high-risk disease in multiple myeloma

scientific article published on 10 June 2020

Evolutionary biology of high-risk multiple myeloma

scientific article published in August 2017

Frequency, distribution and clinical management of incidental findings and extramedullary plasmacytomas in whole body diffusion weighted magnetic resonance imaging in patients with multiple myeloma.

scientific article published on 27 January 2016

Lenalidomide-induced diarrhea in patients with myeloma is caused by bile acid malabsorption that responds to treatment

scientific article published on 01 October 2014

Loss of heterozygosity as a marker of homologous repair deficiency in multiple myeloma: a role for PARP inhibition?

scientific article published on 2 February 2018

Low expression of hexokinase-2 is associated with false-negative FDG-positron emission tomography in multiple myeloma

scientific article published on 21 April 2017

Mutational Spectrum, Copy Number Changes, and Outcome: Results of a Sequencing Study of Patients With Newly Diagnosed Myeloma.

scientific article published on 17 August 2015

Neutral tumor evolution in myeloma is associated with poor prognosis. ⬇️

scientific article published on 21 August 2017

Nuances in the Management of Older People With Multiple Myeloma

scientific article published on 2 April 2016

Optimising the value of immunomodulatory drugs during induction and maintenance in transplant ineligible patients with newly diagnosed multiple myeloma: results from Myeloma XI, a multicentre, open-label, randomised, Phase III trial

scientific article published on 12 July 2020

Overexpression of EZH2 in multiple myeloma is associated with poor prognosis and dysregulation of cell cycle control.

scientific article published on 31 March 2017

Patient experience of whole body diffusion weighted magnetic resonance imaging (WB-MRI) for staging myeloma.

scientific article

Perspectives on the Risk-Stratified Treatment of Multiple Myeloma

Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells

scientific article

Prediction of outcome in newly diagnosed myeloma: a meta-analysis of the molecular profiles of 1905 trial patients. ⬇️

scientific article published on 06 June 2017

Recommendations for vaccination in multiple myeloma: a consensus of the European Myeloma Network

scientific article published on 19 August 2020

Response and biological subtype of myeloma are independent prognostic factors and combine to define outcome after high-dose therapy.

scientific article

Second malignancies in the context of lenalidomide treatment: an analysis of 2732 myeloma patients enrolled to the Myeloma XI trial. ⬇️

scientific article published on 9 December 2016

Serum free immunoglobulin light chain evaluation as a marker of impact from intraclonal heterogeneity on myeloma outcome.

scientific article published on 14 April 2014

The Spectrum and Clinical Impact of Epigenetic Modifier Mutations in Myeloma. ⬇️

scientific article published on 27 May 2016

The efficacy and tolerability of pomalidomide in relapsed/refractory myeloma patients in a "real-world" study: the Royal Marsden Hospital experience

scientific article published on 20 July 2016

The genomic landscape of plasma cells in systemic light chain amyloidosis

scientific article published on 16 November 2018

The impact of long-term lenalidomide exposure on the cellular composition of bone marrow

article

The relative importance of factors predicting outcome for myeloma patients at different ages: results from 3894 patients in the Myeloma XI trial

scientific article published on 14 October 2019

The safety of pomalidomide for the treatment of multiple myeloma

scientific article published on 25 February 2016

The varied distribution and impact of RAS codon and other key DNA alterations across the translocation cyclin D subgroups in multiple myeloma

scientific article

Toward personalized treatment in multiple myeloma based on molecular characteristics

scientific article published on 26 December 2018

Whole-body diffusion-weighted MRI: a new gold standard for assessing disease burden in patients with multiple myeloma?

scientific article published on 09 December 2015

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