List of works - Rachel E Hewitt

A Murine Oral-Exposure Model for Nano- and Micro-Particulates: Demonstrating Human Relevance with Food-Grade Titanium Dioxide

scientific article published on 04 May 2020

An endogenous nanomineral chaperones luminal antigen and peptidoglycan to intestinal immune cells ⬇️

scientific article published on 9 March 2015

Artefactual nanoparticle activation of the inflammasome platform: in vitro evidence with a nano-formed calcium phosphate

scientific article published on 3 July 2014

High Incidence of Spontaneous Disease in an HLA-DR15 and TCR Transgenic Multiple Sclerosis Model

article

High prevalence of autoreactive, neuroantigen-specific CD8+ T cells in multiple sclerosis revealed by novel flow cytometric assay

scientific article published on 19 February 2004

Image-Based Cell Profiling Enables Quantitative Tissue Microscopy in Gastroenterology

scientific article published on 23 May 2020

Imaging flow cytometry assays for quantifying pigment grade titanium dioxide particle internalization and interactions with immune cells in whole blood.

scientific article published on 20 September 2017

Imaging flow cytometry methods for quantitative analysis of label-free crystalline silica particle interactions with immune cells

scientific article published on 26 May 2020

Immuno-inhibitory PD-L1 can be induced by a peptidoglycan/NOD2 mediated pathway in primary monocytic cells and is deficient in Crohn's patients with homozygous NOD2 mutations.

scientific article published on 8 February 2012

Inter-laboratory automation of the in vitro micronucleus assay using imaging flow cytometry and deep learning

scientific article published on 10 July 2021

Intestinal APCs of the endogenous nanomineral pathway fail to express PD-L1 in Crohn's disease.

scientific article published on 26 May 2016

MHC class I molecules with Superenhanced CD8 binding properties bypass the requirement for cognate TCR recognition and nonspecifically activate CTLs.

scientific article published on 26 February 2010

Pro-inflammatory adjuvant properties of pigment-grade titanium dioxide particles are augmented by a genotype that potentiates interleukin 1β processing.

scientific article published on 8 December 2017

Reduction of T-Helper Cell Responses to Recall Antigen Mediated by Codelivery with Peptidoglycan via the Intestinal Nanomineral-Antigen Pathway.

scientific article

Synthetic mimetics of the endogenous gastrointestinal nanomineral: Silent constructs that trap macromolecules for intracellular delivery ⬇️

scientific article published on 29 July 2016

Ultrasmall silica nanoparticles directly ligate the T cell receptor complex

scientific article published on 23 December 2019

List of works by Rachel E Hewitt