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List of works by Dewey G. McCafferty

A crystal structure of a dimer of the antibiotic ramoplanin illustrates membrane positioning and a potential Lipid II docking interface

scientific article published on 03 August 2009

A rationally-designed chimeric KDM1A/KDM1B histone demethylase tower domain deletion mutant retaining enzymatic activity

scientific article

A suppression strategy for antibiotic discovery

scientific article published in October 2004

An economical and preparative orthogonal solid phase synthesis of fluorescein and rhodamine derivatized peptides: FRET substrates for the Staphylococcus aureus sortase SrtA transpeptidase reaction

scientific article published in September 2002

Analysis of the substrate specificity of the Staphylococcus aureus sortase transpeptidase SrtA.

scientific article published in February 2004

Autocatalytic intramolecular isopeptide bond formation in gram-positive bacterial pili: a QM/MM simulation

scientific article

Characterization of Small-Molecule-Induced Changes in Parkinson's-Related Trafficking via the Nedd4 Ubiquitin Signaling Cascade

scientific article published on 03 November 2020

Chemistry and biology of the ramoplanin family of peptide antibiotics

scientific article

Chlamydia Protease-like Activity Factor (CPAF): Characterization of Proteolysis Activity in Vitro and Development of a Nanomolar Affinity CPAF Zymogen-Derived Inhibitor ⬇️

scientific article published on August 15, 2011

Complexation of peptidoglycan intermediates by the lipoglycodepsipeptide antibiotic ramoplanin: minimal structural requirements for intermolecular complexation and fibril formation

scientific article

Critical role of NOD2 in regulating the immune response to Staphylococcus aureus

scientific journal article

Crossing a biological velvet rope

scientific article published on July 2006

Crystal structure of Streptococcus pyogenes sortase A: implications for sortase mechanism

scientific article

Development of a high-performance liquid chromatography assay and revision of kinetic parameters for the Staphylococcus aureus sortase transpeptidase SrtA.

scientific article published in March 2004

Discovery of Six Ramoplanin Family Gene Clusters and the Lipoglycodepsipeptide Chersinamycin

scientific article published on 17 August 2020

Engineering the substrate specificity of Staphylococcus aureus Sortase A. The beta6/beta7 loop from SrtB confers NPQTN recognition to SrtA.

scientific article published on 2 January 2007

Facile synthesis of site-specifically acetylated and methylated histone proteins: reagents for evaluation of the histone code hypothesis

scientific article

Facile synthesis of substituted trans-2-arylcyclopropylamine inhibitors of the human histone demethylase LSD1 and monoamine oxidases A and B.

scientific article published on 8 January 2008

Found in translation: applications of protein and peptide molecular diversity ⬇️

scientific article published on May 23, 2011

Functional analysis of the lipoglycodepsipeptide antibiotic ramoplanin

scientific article published in August 2002

Generation of ramoplanin-resistant Staphylococcus aureus.

scientific article published on 2 July 2010

Histone H3 lysine 4 demethylation is a target of nonselective antidepressive medications

scientific article

Identification of Protease Specificity by Combining Proteome-Derived Peptide Libraries and Quantitative Proteomics

scientific article

Inhibition of the Staphylococcus aureus sortase transpeptidase SrtA by phosphinic peptidomimetics

scientific article published in July 2004

Insights into the Autoproteolytic Processing and Catalytic Mechanism of the Chlamydia trachomatis Virulence-Associated Protease CPAF

scientific article published on 12 August 2019

KDM1 class flavin-dependent protein lysine demethylases

scientific article

Light-induced helix formation

scientific article published on 01 October 2002

Lysine-Specific Demethylase 1A (KDM1A/LSD1): Product Recognition and Kinetic Analysis of Full-Length Histones

scientific article published on 16 December 2015

Lysine-specific histone demethylase 1 inhibitors control breast cancer proliferation in ERα-dependent and -independent manners.

scientific article published on 10 May 2012

Monitoring β-secretase activity in living cells with a membrane-anchored FRET probe

scientific article

Mutagenesis studies of substrate recognition and catalysis in the sortase A transpeptidase from Staphylococcus aureus

scientific article published on 28 March 2008

Mutational analysis of active site residues in the Staphylococcus aureus transpeptidase SrtA

scientific article published on 23 May 2007

Phosphorus-Based SAHA Analogues as Histone Deacetylase Inhibitors†

scientific article published in 2003

Predicting PY motif-mediated protein-protein interactions in the Nedd4 family of ubiquitin ligases

scientific article published on 12 October 2021

Probing of the cis-5-phenyl proline scaffold as a platform for the synthesis of mechanism-based inhibitors of the Staphylococcus aureus sortase SrtA isoform.

scientific article published on 13 February 2009

Profiling natural product biosynthesis

scientific article published on 01 March 2004

Reassessing the role of the secreted protease CPAF in Chlamydia trachomatis infection through genetic approaches

scientific article

Robust and facile purification of full-length, untagged human Nedd4 as a recombinant protein from Escherichia coli

scientific article published on 22 April 2020

Solvent dependence of intramolecular electron transfer in a helical oligoproline assembly

scientific article published in April 2004

Sortase transpeptidases: insights into mechanism, substrate specificity, and inhibition

scientific article

Sortase-catalyzed initiator attachment enables high yield growth of a stealth polymer from the C terminus of a protein.

scientific article published on 09 July 2013

Staphylococcus aureus sortase A contributes to the Trojan horse mechanism of immune defense evasion with its intrinsic resistance to Cys184 oxidation.

scientific article published on 10 August 2011

Staphylococcus aureus sortase transpeptidase SrtA: insight into the kinetic mechanism and evidence for a reverse protonation catalytic mechanism

scientific article published in August 2005

Studies on the biosynthesis of the lipodepsipeptide antibiotic Ramoplanin A2 ⬇️

scientific article published on 07 December 2011

Techniques used to study transcription on chromatin templates

scientific article published on January 2004

The Chlamydia Protease CPAF Regulates Host and Bacterial Proteins to Maintain Pathogen Vacuole Integrity and Promote Virulence ⬇️

scientific article published on July 21, 2011

The Chlamydia trachomatis Protease CPAF Contains a Cryptic PDZ-Like Domain with Similarity to Human Cell Polarity and Tight Junction PDZ-Containing Proteins

scientific article published in February 2016

Thermodynamic characterization of the binding interaction between the histone demethylase LSD1/KDM1 and CoREST.

scientific article published on 30 December 2010

Three-in-one chromatography-free purification, tag removal, and site-specific modification of recombinant fusion proteins using sortase A and elastin-like polypeptides

scientific article published on 19 February 2013

Use of pH and kinetic isotope effects to establish chemistry as rate-limiting in oxidation of a peptide substrate by LSD1.

scientific article published on June 2009

Vinyl sulfones: inhibitors of SrtA, a transpeptidase required for cell wall protein anchoring and virulence in Staphylococcus aureus

scientific article published in March 2004

trans-2-Phenylcyclopropylamine is a mechanism-based inactivator of the histone demethylase LSD1.

scientific article

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