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List of works by Sarah Pendergrass

A Phenome-Wide Association Study Uncovers a Role for Autoimmunity in the Development of Chronic Obstructive Pulmonary Disease.

scientific article published in June 2018

A Trans-Ethnic Genome-Wide Association Study of Uterine Fibroids.

scientific article published on 12 June 2019

A catalog of genetic loci associated with kidney function from analyses of a million individuals

scientific article published on 31 May 2019

A core MYC gene expression signature is prominent in basal-like breast cancer but only partially overlaps the core serum response

scientific article

A phenome-wide association study (PheWAS) in the Population Architecture using Genomics and Epidemiology (PAGE) study reveals potential pleiotropy in African Americans

scientific article published on 31 December 2019

A phenome-wide association study to discover pleiotropic effects of , , and

A phenomics-based strategy identifies loci on APOC1, BRAP, and PLCG1 associated with metabolic syndrome phenotype domains

scientific article

A simulation study investigating power estimates in phenome-wide association studies.

scientific article

ATHENA: the analysis tool for heritable and environmental network associations

scientific article published on 21 October 2013

Antagonistic effect of the matricellular signaling protein CCN3 on TGF-beta- and Wnt-mediated fibrillinogenesis in systemic sclerosis and Marfan syndrome.

scientific article

Association of the FTO obesity risk variant rs8050136 with percentage of energy intake from fat in multiple racial/ethnic populations: the PAGE study

scientific article published on 02 July 2013

Author Correction: Rare variants in drug target genes contributing to complex diseases, phenome-wide

scientific article published in Scientific Reports

BioBin: a bioinformatics tool for automating the binning of rare variants using publicly available biological knowledge

scientific article

Biology-Driven Gene-Gene Interaction Analysis of Age-Related Cataract in the eMERGE Network

scientific article

Characterization of mitochondrial haplogroups in a large population-based sample from the United States

scientific article

Characterizing and Managing Missing Structured Data in Electronic Health Records: Data Analysis.

scientific article

Comparative evaluation of strain-based and model-based modulus elastography

scientific article published in June 2005

Consistent directions of effect for established type 2 diabetes risk variants across populations: the population architecture using Genomics and Epidemiology (PAGE) Consortium

scientific article

Contrasting Association Results between Existing PheWAS Phenotype Definition Methods and Five Validated Electronic Phenotypes

scientific article published on 5 November 2015

Correction: Molecular Subsets in the Gene Expression Signatures of Scleroderma Skin.

scientific article published on 8 October 2008

Detecting and Characterizing Pleiotropy: New Methods for Uncovering the Connection Between the Complexity of Genomic Architecture and Multiple phenotypes

scientific article published on January 2014

Detecting potential pleiotropy across cardiovascular and neurological diseases using univariate, bivariate, and multivariate methods on 43,870 individuals from the eMERGE network

Detection of pleiotropy through a Phenome-wide association study (PheWAS) of epidemiologic data as part of the Environmental Architecture for Genes Linked to Environment (EAGLE) study

scientific article

Distribution and clinical impact of functional variants in 50,726 whole-exome sequences from the DiscovEHR study

scientific article published on December 2016

Diverse convergent evidence in the genetic analysis of complex disease: coordinating omic, informatic, and experimental evidence to better identify and validate risk factors

scientific article

Electronic health record phenotype in subjects with genetic variants associated with arrhythmogenic right ventricular cardiomyopathy: a study of 30,716 subjects with exome sequencing

scientific article published on 4 May 2017

Enabling high-throughput genotype-phenotype associations in the Epidemiologic Architecture for Genes Linked to Environment (EAGLE) project as part of the Population Architecture using Genomics and Epidemiology (PAGE) study

scientific article (publication date: 2013)

Environment-wide association study (EWAS) for type 2 diabetes in the Marshfield Personalized Medicine Research Project Biobank

scientific article

Evidence for extensive pleiotropy among pharmacogenes

scientific article published on June 2016

First Trimester Plasma Glucose Values in Women without Diabetes are Associated with Risk for Congenital Heart Disease in Offspring

scientific article published on 13 December 2017

Genetic determinants of lipid traits in diverse populations from the population architecture using genomics and epidemiology (PAGE) study

scientific article

Genetic variants associated with fasting glucose and insulin concentrations in an ethnically diverse population: results from the Population Architecture using Genomics and Epidemiology (PAGE) study

scientific article

Genome-wide analysis of mRNAs bound to the histone stem-loop binding protein

scientific article

Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria

scientific article published on 11 September 2019

Genomic analyses with biofilter 2.0: knowledge driven filtering, annotation, and model development

scientific article

Genomic architecture of pharmacological efficacy and adverse events

scientific article

IDENTIFYING GENETIC ASSOCIATIONS WITH VARIABILITY IN METABOLIC HEALTH AND BLOOD COUNT LABORATORY VALUES: DIVING INTO THE QUANTITATIVE TRAITS BY LEVERAGING LONGITUDINAL DATA FROM AN EHR.

scientific article

INTEGRATING CLINICAL LABORATORY MEASURES AND ICD-9 CODE DIAGNOSES IN PHENOME-WIDE ASSOCIATION STUDIES.

scientific article

Interferon and alternative activation of monocyte/macrophages in systemic sclerosis-associated pulmonary arterial hypertension.

scientific article

Intrinsic gene expression subsets of diffuse cutaneous systemic sclerosis are stable in serial skin biopsies.

scientific article published on 9 February 2012

Investigating the relationship between mitochondrial genetic variation and cardiovascular-related traits to develop a framework for mitochondrial phenome-wide association studies

scientific article

Knowledge-driven genomic interactions: an application in ovarian cancer

scientific article

Leveraging Epidemiologic and Clinical Collections for Genomic Studies of Complex Traits

scientific article published on 28 July 2015

Limited systemic sclerosis patients with pulmonary arterial hypertension show biomarkers of inflammation and vascular injury

scientific article

Low frequency variants, collapsed based on biological knowledge, uncover complexity of population stratification in 1000 genomes project data

scientific article

Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci ⬇️

scientific article

Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline

scientific article published on 30 October 2020

Methods of integrating data to uncover genotype-phenotype interactions

scientific article

Microwave thermal imaging: initial in vivo experience with a single heating zone

scientific article published in November 2003

Molecular subsets in the gene expression signatures of scleroderma skin

scientific article

Multiancestral analysis of inflammation-related genetic variants and C-reactive protein in the population architecture using genomics and epidemiology study

scientific article

Multiphenotype association study of patients randomized to initiate antiretroviral regimens in AIDS Clinical Trials Group protocol A5202.

scientific article published on 05 January 2017

Next-generation analysis of cataracts: determining knowledge driven gene-gene interactions using Biofilter, and gene-environment interactions using the PhenX Toolkit.

scientific article published on January 2013

Next-generation analysis of cataracts: determining knowledge driven gene-gene interactions using biofilter, and gene-environment interactions using the Phenx Toolkit*.

scientific article

OPENING THE DOOR TO THE LARGE SCALE USE OF CLINICAL LAB MEASURES FOR ASSOCIATION TESTING: EXPLORING DIFFERENT METHODS FOR DEFINING PHENOTYPES.

scientific article published on January 2016

PATTERNS IN BIOMEDICAL DATA-HOW DO WE FIND THEM?

scientific article

PHENOME-WIDE INTERACTION STUDY (PheWIS) IN AIDS CLINICAL TRIALS GROUP DATA (ACTG).

scientific article

PLATO software provides analytic framework for investigating complexity beyond genome-wide association studies

scientific article published on 27 October 2017

Pathway analysis by randomization incorporating structure-PARIS: an update

scientific article published on 7 March 2016

PheWAS and Beyond: The Landscape of Associations with Medical Diagnoses and Clinical Measures across 38,662 Individuals from Geisinger

scientific article published on 19 March 2018

Phenome-Wide Association Studies: Embracing Complexity for Discovery

scientific article (publication date: 2015)

Phenome-Wide Association Study to Explore Relationships between Immune System Related Genetic Loci and Complex Traits and Diseases

scientific article

Phenome-wide Association Study Relating Pretreatment Laboratory Parameters With Human Genetic Variants in AIDS Clinical Trials Group Protocols

scientific article

Phenome-wide association studies demonstrating pleiotropy of genetic variants within FTO with and without adjustment for body mass index

scientific article

Phenome-wide association study (PheWAS) for detection of pleiotropy within the Population Architecture using Genomics and Epidemiology (PAGE) Network

scientific article

Pleiotropic genes for metabolic syndrome and inflammation

scientific article

Polygenic heritability estimates in pharmacogenetics: focus on asthma and related phenotypes

scientific article published on June 2013

Polygenic inheritance of paclitaxel-induced sensory peripheral neuropathy driven by axon outgrowth gene sets in CALGB 40101 (Alliance).

scientific article

Rare variants in drug target genes contributing to complex diseases, phenome-wide

scientific article published on 15 March 2018

Real world scenarios in rare variant association analysis: the impact of imbalance and sample size on the power in silico

Regulatory polymorphisms in human DBH affect peripheral gene expression and sympathetic activity

scientific article

Synthesis-View: visualization and interpretation of SNP association results for multi-cohort, multi-phenotype data and meta-analysis

scientific article

Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data

scientific article

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

scientific article published on 02 October 2019

The detection and characterization of pleiotropy: discovery, progress, and promise

scientific article published on 28 July 2015

The importance of buprenorphine research in the opioid crisis

scientific article published on 07 January 2019

The joint effect of air pollution exposure and copy number variation on risk for autism.

scientific article published on 27 April 2017

Towards a phenome-wide catalog of human clinical traits impacted by genetic ancestry.

scientific article

Uncovering the etiology of autism spectrum disorders: genomics, bioinformatics, environment, data collection and exploration, and future possibilities

scientific article

Understanding systemic sclerosis through gene expression profiling

scientific article published on November 2007

Unfolding of hidden white blood cell count phenotypes for gene discovery using latent class mixed modeling

article

Using Adipose Measures from Health Care Provider-Based Imaging Data for Discovery

Using BioBin to explore rare variant population stratification

scientific article published on January 2013

Visual integration of results from a large DNA biobank (BioVU) using synthesis-view

scientific article published on January 2011

Visualizing genomic information across chromosomes with PhenoGram

scientific article

Visually integrating and exploring high throughput Phenome-Wide Association Study (PheWAS) results using PheWAS-View

scientific article

eMERGE Phenome-Wide Association Study (PheWAS) identifies clinical associations and pleiotropy for stop-gain variants

scientific article

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