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List of works by Chia-Hsin Chan

Critical Role of Monoubiquitination of Histone H2AX Protein in Histone H2AX Phosphorylation and DNA Damage Response ⬇️

scientific article published on June 20, 2011

Deciphering the transcriptional complex critical for RhoA gene expression and cancer metastasis.

scientific article published on 11 April 2010

E3-ligase Skp2 regulates β-catenin expression and maintains hematopoietic stem cell homing.

scientific article published on 18 February 2014

Erratum: Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence

scientific article published in Nature

JARID1D Is a Suppressor and Prognostic Marker of Prostate Cancer Invasion and Metastasis.

scientific article published on 08 January 2016

KDM2A promotes lung tumorigenesis by epigenetically enhancing ERK1/2 signaling.

scientific article

Novel ARF/p53-independent senescence pathways in cancer repression.

scientific article published on 19 May 2011

Novel roles of Skp2 E3 ligase in cellular senescence, cancer progression, and metastasis ⬇️

scientific article published on December 23, 2011

Pharmacological inactivation of Skp2 SCF ubiquitin ligase restricts cancer stem cell traits and cancer progression ⬇️

scientific article

Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB

scientific article

Posttranslational regulation of Akt in human cancer

scientific article

Regulation of Skp2 expression and activity and its role in cancer progression

scientific article

Regulation of intrinsic and extrinsic metabolic pathways in tumour‐associated macrophages

scientific article published in 2022

Skp2 E3 ligase integrates ATM activation and homologous recombination repair by ubiquitinating NBS1.

scientific article

Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence

scientific article

Skp2-Mediated RagA Ubiquitination Elicits a Negative Feedback to Prevent Amino-Acid-Dependent mTORC1 Hyperactivation by Recruiting GATOR1.

scientific article published on 4 June 2015

Skp2-dependent ubiquitination and activation of LKB1 is essential for cancer cell survival under energy stress

scientific article published on 26 February 2015

Skp2-macroH2A1-CDK8 axis orchestrates G2/M transition and tumorigenesis

scientific article published on 30 March 2015

Skp2: a dream target in the coming age of cancer therapy.

scientific article published on 21 January 2014

Subcellular and functional proteomic analysis of the cellular responses induced by Helicobacter pylori.

scientific article

Tackling Cancer Stem Cells via Inhibition of EMT Transcription Factors

scientific article

The DNA Damage Transducer RNF8 Facilitates Cancer Chemoresistance and Progression through Twist Activation

scientific article published on 03 September 2016

The Skp2-SCF E3 ligase regulates Akt ubiquitination, glycolysis, herceptin sensitivity, and tumorigenesis

scientific article

The Ubiquitin Ligase RNF8 Regulates Rho GTPases and Promotes Cytoskeletal Changes and Motility in Triple-Negative Breast Cancer Cells

scientific article published on 17 November 2020

The role of Skp2 in hematopoietic stem cell quiescence, pool size, and self-renewal

scientific article published on 19 September 2011

UTX and MLL4 coordinately regulate transcriptional programs for cell proliferation and invasiveness in breast cancer cells

scientific article

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