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List of works by Xavier León

Alteration of sugar-induced conformational changes of the melibiose permease by mutating Arg141 in loop 4-5

scientific article published on June 2009

BMP7 overexpression in adipose tissue induces white adipogenesis and improves insulin sensitivity in ob/ob mice

scientific article published on 27 October 2020

Biochemical, histological and functional correction of mucopolysaccharidosis type IIIB by intra-cerebrospinal fluid gene therapy

scientific article published on 18 December 2014

CNS-directed gene therapy for the treatment of neurologic and somatic mucopolysaccharidosis type II (Hunter syndrome)

scientific article

Changes in secondary structures and acidic side chains of melibiose permease upon cosubstrates binding.

scientific article published on 29 September 2006

Characterization of a recombinant adeno-associated virus type 2 Reference Standard Material

scientific article

Disease correction by AAV-mediated gene therapy in a new mouse model of mucopolysaccharidosis type IIID.

scientific article published on 17 February 2017

High AAV vector purity results in serotype- and tissue-independent enhancement of transduction efficiency

scientific article published on 3 December 2009

In-plane and out-of-plane infrared difference spectroscopy unravels tilting of helices and structural changes in a membrane protein upon substrate binding

scientific article published in October 2009

Manufacturing and characterization of a recombinant adeno-associated virus type 8 reference standard material.

scientific article

Structural insights into the activation mechanism of melibiose permease by sodium binding.

scientific article

Studying substrate binding to reconstituted secondary transporters by attenuated total reflection infrared difference spectroscopy

scientific article

Substrate-induced conformational changes of melibiose permease from Escherichia coli studied by infrared difference spectroscopy.

scientific article

Treatment of skeletal and non-skeletal alterations of Mucopolysaccharidosis type IVA by AAV-mediated gene therapy

scientific article published on 09 September 2021

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