List of works - Lisa Westerberg

A linkage study of candidate loci in familial Parkinson's Disease

scientific article

A novel mouse model for the hyper-IgM syndrome: a spontaneous activation-induced cytidine deaminase mutation leading to complete loss of Ig class switching and reduced somatic hypermutation

scientific article

Activating WASP mutations associated with X-linked neutropenia result in enhanced actin polymerization, altered cytoskeletal responses, and genomic instability in lymphocytes

scientific article

Activation of compensatory pathways via Rac2 in the absence of the Cdc42 effector Wiskott-Aldrich syndrome protein in Dendritic cells.

scientific article published on 27 January 2017

Akt2 Regulates the Differentiation and Function of NKT17 Cells via FoxO-1-ICOS Axis

scientific article published on 12 September 2018

Alternative Splicing of FOXP3 Controls Regulatory T Cell Effector Functions and Is Associated With Human Atherosclerotic Plaque Stability

scientific article published on 04 April 2018

An intronic deletion in megakaryoblastic leukemia 1 is associated with hyperproliferation of B cells in triplets with Hodgkin lymphoma

scientific article published on 03 October 2019

B cell-intrinsic deficiency of the Wiskott-Aldrich syndrome protein (WASp) causes severe abnormalities of the peripheral B-cell compartment in mice.

scientific article published in February 2012

Buzz in the dendritic cell synapse

scientific article published on 01 September 2011

CD36 and LC3B initiated autophagy in B cells regulates the humoral immune response

scientific article published on 16 February 2021

CD73 immune checkpoint defines regulatory NK cells within the tumor microenvironment

scientific article published on 01 March 2020

CX3CR1 positively regulates BCR signaling coupled with cell metabolism via negatively controlling actin remodeling

scientific article published on 04 February 2020

Cdc42, Rac1, and the Wiskott-Aldrich syndrome protein are involved in the cytoskeletal regulation of B lymphocytes

scientific article published on 01 August 2001

Congenital Defects in Actin Dynamics of Germinal Center B Cells

scientific article published on 06 March 2019

Congenital defects in neutrophil dynamics

scientific article

Constitutive activation of WASp in X-linked neutropenia renders neutrophils hyperactive

scientific article published on 20 August 2018

Cytoskeletal regulation of dendritic cells: An intricate balance between migration and presentation for tumor therapy

scientific article published on 18 June 2020

Defective thymic output in WAS patients is associated with abnormal actin organization

scientific article published on 20 September 2017

Deletion of Dock10 in B Cells Results in Normal Development but a Mild Deficiency upon In Vivo and In Vitro Stimulations.

scientific article published on May 2017

Deletion of WASp and N-WASp in B cells cripples the germinal center response and results in production of IgM autoantibodies

scientific article published on 2 July 2015

Deletion of Wiskott-Aldrich syndrome protein triggers Rac2 activity and increased cross-presentation by dendritic cells

scientific article published on 18 July 2016

Expression of alpha-synuclein in the human brain: relation to Lewy body disease.

scientific article published in August 2001

Flt3 ligand expands bona fide innate lymphoid cell precursors in vivo

scientific article published on 9 January 2018

Foxp3 lacking exons 2 and 7 is unable to confer suppressive ability to regulatory T cells in vivo.

scientific article published on 3 July 2015

H1N1 vaccination in Sjögren's syndrome triggers polyclonal B cell activation and promotes autoantibody production

scientific article published on 31 July 2017

Human 15-lipoxygenase-1 is a regulator of dendritic-cell spreading and podosome formation

scientific article published on 17 October 2016

IL-2 in the tumor microenvironment is necessary for Wiskott-Aldrich syndrome protein deficient NK cells to respond to tumors in vivo.

scientific article published on August 2016

Insulin influences autophagy response distinctively in macrophages of different compartments

scientific article published on 26 November 2014

Interferon γ is a STAT1-dependent direct inducer of BCL6 expression in imatinib-treated chronic myeloid leukemia cells.

scientific article published on 3 April 2017

Methods to Study the Role of Cdc42, Rac1, and Rac2 in B-Cell Cytoskeletal Responses

scientific article published on 01 January 2018

Microvilli structures on B lymphocytes: inducible functional domains?

scientific article

Multi-faceted inhibition of dendritic cell function by CD4+Foxp3+ regulatory T cells

scientific article published on 05 January 2019

N-WASP is required for B-cell-mediated autoimmunity in Wiskott-Aldrich syndrome.

scientific article

N-wasp is essential for the negative regulation of B cell receptor signaling.

scientific article

Nuclear Wiskott-Aldrich syndrome protein co-regulates T cell factor 1-mediated transcription in T cells.

scientific article published on 27 October 2017

Phosphorylation of WASp is a key regulator of activity and stability in vivo

scientific article published on September 2009

Rictor positively regulates B cell receptor signaling by modulating actin reorganization via ezrin

scientific article published on 18 August 2017

The Rho GTPase Cdc42 Is Essential for the Activation and Function of Mature B Cells.

scientific article published on 13 April 2015

The Small Rho GTPases Rac1 and Rac2 Are Important for T-Cell Independent Antigen Responses and for Suppressing Switching to IgG2b in Mice

scientific article published on 6 October 2017

Unraveling the repertoire in wiskott-Aldrich syndrome

scientific article

Wiskott Aldrich syndrome protein (WASP) and N-WASP are critical for T cell development.

scholarly article

Wiskott-Aldrich syndrome gene mutations modulate cancer susceptibility in the p53 murine model

article

Wiskott-Aldrich syndrome protein deficiency leads to reduced B-cell adhesion, migration, and homing, and a delayed humoral immune response

article

Wiskott-Aldrich syndrome protein regulates autophagy and inflammasome activity in innate immune cells

scientific article

List of works by Lisa Westerberg

A linkage study of candidate loci in familial Parkinson's Disease

A novel mouse model for the hyper-IgM syndrome: a spontaneous activation-induced cytidine deaminase mutation leading to complete loss of Ig class switching and reduced somatic hypermutation

Activating WASP mutations associated with X-linked neutropenia result in enhanced actin polymerization, altered cytoskeletal responses, and genomic instability in lymphocytes

Activation of compensatory pathways via Rac2 in the absence of the Cdc42 effector Wiskott-Aldrich syndrome protein in Dendritic cells.

Akt2 Regulates the Differentiation and Function of NKT17 Cells via FoxO-1-ICOS Axis

Alternative Splicing of FOXP3 Controls Regulatory T Cell Effector Functions and Is Associated With Human Atherosclerotic Plaque Stability

An intronic deletion in megakaryoblastic leukemia 1 is associated with hyperproliferation of B cells in triplets with Hodgkin lymphoma

B cell-intrinsic deficiency of the Wiskott-Aldrich syndrome protein (WASp) causes severe abnormalities of the peripheral B-cell compartment in mice.

Buzz in the dendritic cell synapse

CD36 and LC3B initiated autophagy in B cells regulates the humoral immune response

CD73 immune checkpoint defines regulatory NK cells within the tumor microenvironment

CX3CR1 positively regulates BCR signaling coupled with cell metabolism via negatively controlling actin remodeling

Cdc42, Rac1, and the Wiskott-Aldrich syndrome protein are involved in the cytoskeletal regulation of B lymphocytes

Congenital Defects in Actin Dynamics of Germinal Center B Cells

Congenital defects in neutrophil dynamics

Constitutive activation of WASp in X-linked neutropenia renders neutrophils hyperactive

Cytoskeletal regulation of dendritic cells: An intricate balance between migration and presentation for tumor therapy

Defective thymic output in WAS patients is associated with abnormal actin organization

Deletion of Dock10 in B Cells Results in Normal Development but a Mild Deficiency upon In Vivo and In Vitro Stimulations.

Deletion of WASp and N-WASp in B cells cripples the germinal center response and results in production of IgM autoantibodies

Deletion of Wiskott-Aldrich syndrome protein triggers Rac2 activity and increased cross-presentation by dendritic cells

Expression of alpha-synuclein in the human brain: relation to Lewy body disease.

Flt3 ligand expands bona fide innate lymphoid cell precursors in vivo

Foxp3 lacking exons 2 and 7 is unable to confer suppressive ability to regulatory T cells in vivo.

H1N1 vaccination in Sjögren's syndrome triggers polyclonal B cell activation and promotes autoantibody production

Human 15-lipoxygenase-1 is a regulator of dendritic-cell spreading and podosome formation

IL-2 in the tumor microenvironment is necessary for Wiskott-Aldrich syndrome protein deficient NK cells to respond to tumors in vivo.

Insulin influences autophagy response distinctively in macrophages of different compartments

Interferon γ is a STAT1-dependent direct inducer of BCL6 expression in imatinib-treated chronic myeloid leukemia cells.

Methods to Study the Role of Cdc42, Rac1, and Rac2 in B-Cell Cytoskeletal Responses

Microvilli structures on B lymphocytes: inducible functional domains?

Multi-faceted inhibition of dendritic cell function by CD4+Foxp3+ regulatory T cells

N-WASP is required for B-cell-mediated autoimmunity in Wiskott-Aldrich syndrome.

N-wasp is essential for the negative regulation of B cell receptor signaling.

Nuclear Wiskott-Aldrich syndrome protein co-regulates T cell factor 1-mediated transcription in T cells.

Phosphorylation of WASp is a key regulator of activity and stability in vivo

Rictor positively regulates B cell receptor signaling by modulating actin reorganization via ezrin

The Rho GTPase Cdc42 Is Essential for the Activation and Function of Mature B Cells.

The Small Rho GTPases Rac1 and Rac2 Are Important for T-Cell Independent Antigen Responses and for Suppressing Switching to IgG2b in Mice

Unraveling the repertoire in wiskott-Aldrich syndrome

Wiskott Aldrich syndrome protein (WASP) and N-WASP are critical for T cell development.

Wiskott-Aldrich syndrome gene mutations modulate cancer susceptibility in the p53 murine model

Wiskott-Aldrich syndrome protein deficiency leads to reduced B-cell adhesion, migration, and homing, and a delayed humoral immune response

Wiskott-Aldrich syndrome protein regulates autophagy and inflammasome activity in innate immune cells