List of works by John D Isaacs

"Living a normal life": a qualitative study of patients' views of medication withdrawal in rheumatoid arthritis

scientific article published on 13 June 2019

10 years of therapeutic advances in the rheumatic diseases

scientific article published on 13 October 2015

A CD4 T cell gene signature for early rheumatoid arthritis implicates interleukin 6-mediated STAT3 signalling, particularly in anti-citrullinated peptide antibody-negative disease.

scientific article

A Transcriptional Signature of Fatigue Derived from Patients with Primary Sjögren's Syndrome

scientific article published on 22 December 2015

A negative feedback loop mediated by STAT3 limits human Th17 responses.

scientific article published on 27 June 2014

A non-glycosaminoglycan-binding variant of CC chemokine ligand 7 (monocyte chemoattractant protein-3) antagonizes chemokine-mediated inflammation

scientific article published on July 2005

A novel paradigm for dendritic cells as effectors of cartilage destruction.

scientific article published on 5 March 2009

A phase 1 study to address the safety and efficacy of granulocyte colony-stimulating factor for the mobilization of hematopoietic progenitor cells in active rheumatoid arthritis

scientific article published on 01 October 1997

A pilot study of combination anti-cytokine and anti-lymphocyte biological therapy in rheumatoid arthritis.

scientific article published on 19 February 2008

A randomised, controlled, double blinded study of ultrasound guided corticosteroid joint injection in patients with inflammatory arthritis

scientific article published on 01 July 2010

A therapeutic human IgG4 monoclonal antibody that depletes target cells in humans

scientific article published on 01 December 1996

Abnormal T cell differentiation persists in patients with rheumatoid arthritis in clinical remission and predicts relapse.

scientific article published on 20 July 2007

Achieving consensus on minimum data items (including core outcome domains) for a longitudinal observational cohort study in rheumatoid arthritis

scientific article

Adrenal steroidogenesis after B lymphocyte depletion therapy in new-onset Addison's disease

scientific article

Adult Human Fibroblasts Are Potent Immunoregulatory Cells and Functionally Equivalent to Mesenchymal Stem Cells

scientific article published on 01 August 2007

Analysis of Fcgamma receptor haplotypes in rheumatoid arthritis: FCGR3A remains a major susceptibility gene at this locus, with an additional contribution from FCGR3B.

scientific article

Animal models in infection and inflammation - chance and necessity

scientific article published on 01 August 2009

Anti-TNF therapy

scientific article published on August 2011

Anti-TNFα Therapy Modulates the Phenotype of Peripheral Blood CD4+T Cells in Patients with Posterior Segment Intraocular Inflammation

scientific article published on 01 January 2004

Antibody engineering to develop new antirheumatic therapies

scientific article published on 19 May 2009

Application of differential display to immunological research.

scientific article

Association between anti-tumour necrosis factor treatment response and genetic variants within the TLR and NF B signalling pathways

article

Association of FCGR2A and FCGR2A-FCGR3A haplotypes with susceptibility to giant cell arteritis

scientific article published on January 2006

Association of HLA-DRB1 haplotypes with rheumatoid arthritis severity, mortality, and treatment response

scientific article published on April 2015

Association of response to TNF inhibitors in rheumatoid arthritis with quantitative trait loci for and CD39

article

Association of rheumatoid factor and anti-cyclic citrullinated peptide positivity, but not carriage of shared epitope or PTPN22 susceptibility variants, with anti-tumour necrosis factor response in rheumatoid arthritis

scientific article published on 28 March 2008

Association of the tumour necrosis factor-308 variant with differential response to anti-TNF agents in the treatment of rheumatoid arthritis

article

Atacicept, a novel B cell-targeting biological therapy for the treatment of rheumatoid arthritis.

scientific article published on July 2009

Autologous tolerogenic dendritic cells for rheumatoid and inflammatory arthritis

scientific article published on 26 April 2016

Baseline serum MMP-3 levels in patients with Rheumatoid Arthritis are still independently predictive of radiographic progression in a longitudinal observational cohort at 8 years follow up

scientific article

Bcl-3 in CD4+ T Cell-Mediated Rheumatoid Arthritis Pathogenesis: Comment on the Article by Meguro et al

scientific article published on 01 March 2016

Between a ROC and a hard place: Teaching prevalence plots to understand real world biomarker performance in the clinic

scientific article published on 23 June 2019

Biologic refractory disease in rheumatoid arthritis: results from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis

scientific article published on 06 July 2018

Biologic therapies in non-rheumatic diseases: lessons for rheumatologists?

scientific article published on 02 August 2011

Biologic therapies in rheumatology: lessons learned, future directions

scientific article published on January 2007

Biosimilars in immune-mediated inflammatory diseases: initial lessons from the first approved biosimilar anti-tumour necrosis factor monoclonal antibody.

scientific article published on 25 September 2015

CD4+ and B Lymphocyte Expression Quantitative Traits at Rheumatoid Arthritis Risk Loci in Patients With Untreated Early Arthritis: Implications for Causal Gene Identification.

scientific article published on 28 November 2017

CD4+CD25+ T-regulatory cells are decreased in patients with autoimmune polyendocrinopathy candidiasis ectodermal dystrophy

article

CMV seropositivity and T-cell senescence predict increased cardiovascular mortality in octogenarians: results from the Newcastle 85+ study

scientific article published on 22 December 2015

Capture Hi-C identifies a novel causal gene, IL20RA, in the pan-autoimmune genetic susceptibility region 6q23

scientific article (publication date: November 2016)

Changes in serum creatinine in patients with active rheumatoid arthritis treated with tofacitinib: results from clinical trials

scientific article

Clinical trials of biosimilars should become more similar

scientific article published on 25 August 2016

Clinical utility of random anti-tumor necrosis factor drug-level testing and measurement of antidrug antibodies on the long-term treatment response in rheumatoid arthritis

scientific article published on May 2015

Clinical utility of random anti-tumour necrosis factor drug testing and measurement of anti-drug antibodies on long-term treatment response in rheumatoid arthritis.

scientific article published on February 2015

Components of treatment delay in rheumatoid arthritis differ according to autoantibody status: validation of a single-centre observation using national audit data.

scientific article

Confirmation of association of FCGR3B but not FCGR3A copy number with susceptibility to autoantibody positive rheumatoid arthritis.

scientific article published on 28 February 2012

Correlation of C-reactive protein haplotypes with serum C-reactive protein level and response to anti-tumor necrosis factor therapy in UK rheumatoid arthritis patients: results from the Biologics in Rheumatoid Arthritis Genetics and Genomics Study S

scientific article published on 7 October 2012

Current concepts in the pathogenesis of early rheumatoid arthritis

scientific article published on February 2009

Cytokines in rheumatoid arthritis - shaping the immunological landscape

scientific article

Defective removal of ribonucleotides from DNA promotes systemic autoimmunity.

scientific article

Defective removal of ribonucleotides from DNA promotes systemic lupus erythematosus.

scientific article published on 28 September 2015

Design of experiments and the virtual PCR simulator: An online game for pharmaceutical scientists and biotechnologists

scientific article published on 21 February 2019

Detection of Mycobacterium tuberculosis group organisms in human and mouse joint tissue by reverse transcriptase PCR: prevalence in diseased synovial tissue suggests lack of specific association with rheumatoid arthritis

scientific article

Detection of anti-drug antibodies using a bridging ELISA compared with radioimmunoassay in adalimumab-treated rheumatoid arthritis patients with random drug levels.

scientific article published on 25 August 2016

Determination of thymic function directly from peripheral blood: a validated modification to an established method.

scientific article published on 12 October 2008

Development of dendritic cell-based immunotherapy for autoimmunity

scientific article published on April 2010

Differential Methylation as a Biomarker of Response to Etanercept in Patients With Rheumatoid Arthritis

scientific article published on 27 January 2016

Differential regulation of naïve and memory CD4+ T cells by alternatively activated dendritic cells

scientific article published on 22 April 2008

Disease activity and cognition in rheumatoid arthritis: an open label pilot study

scientific article published on 4 December 2012

Dissection of the FCGR3A association with RA: increased association in men and with autoantibody positive disease

scientific article published on 20 August 2009

Drug breakthrough offers hope to arthritis sufferers: qualitative analysis of medical research in UK newspapers.

scientific article published on 04 May 2016

Dysregulated lymphocyte proliferation and differentiation in patients with rheumatoid arthritis.

scientific article published on 8 August 2002

EULAR provisional recommendations for the management of rheumatic and musculoskeletal diseases in the context of SARS-CoV-2

scientific article published on 05 June 2020

Effect of baseline rheumatoid factor and anticitrullinated peptide antibody serotype on rituximab clinical response: a meta-analysis

scientific article

Effect of tocilizumab on haematological markers implicates interleukin-6 signalling in the anaemia of rheumatoid arthritis

scientific article published on January 2013

Efficacy and safety of secukinumab, a fully human anti-interleukin-17A monoclonal antibody, in patients with moderate-to-severe psoriatic arthritis: a 24-week, randomised, double-blind, placebo-controlled, phase II proof-of-concept trial

scientific article published on 29 January 2013

Efficacy of a single ultrasound-guided injection for the treatment of hip osteoarthritis

scientific article published on 10 November 2010

Elucidation of the relationship between synovitis and bone damage: A randomized magnetic resonance imaging study of individual joints in patients with early rheumatoid arthritis

article

Emerging immunotherapies for rheumatoid arthritis.

scientific article published on 17 February 2014

Epstein-Barr virus-driven lymphoproliferative disorder post-CAMPATH-1H (alemtuzumab) in refractory polymyositis

scientific article published on 5 January 2011

Evaluation of the effect of tofacitinib on measured glomerular filtration rate in patients with active rheumatoid arthritis: results from a randomised controlled trial

scientific article published on 6 April 2015

Evidence of NLRP3-inflammasome activation in rheumatoid arthritis (RA); genetic variants within the NLRP3-inflammasome complex in relation to susceptibility to RA and response to anti-TNF treatment

scientific article published on 17 May 2013

Fc gamma receptors are critical modulators of inflammation within the synovium: comment on the article by Blom et al.

scientific article published in April 2004

Fcgamma receptor type IIIA is associated with rheumatoid arthritis in two distinct ethnic groups

scientific article published on 01 October 2000

FcγRIIIa expression on monocytes in rheumatoid arthritis: role in immune-complex stimulated TNF production and non-response to methotrexate therapy

scientific article published on 3 January 2012

Frailty and the role of inflammation, immunosenescence and cellular ageing in the very old: cross-sectional findings from the Newcastle 85+ Study.

scientific article

Generation and characterisation of therapeutic tolerogenic dendritic cells for rheumatoid arthritis.

scientific article published on 15 June 2010

Genetic variants within the MAP kinase signalling network and anti-TNF treatment response in rheumatoid arthritis patients

scientific article

Genome-wide association study and gene expression analysis identifies CD84 as a predictor of response to etanercept therapy in rheumatoid arthritis

scientific article

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

scientific article

Genome-wide association study of genetic predictors of anti-tumor necrosis factor treatment efficacy in rheumatoid arthritis identifies associations with polymorphisms at seven loci

scientific article

Genotyping in rheumatoid arthritis: a game changer in clinical management?

scientific article published on 02 February 2015

High frequency of antidrug antibodies and association of random drug levels with efficacy in certolizumab pegol-treated patients with rheumatoid arthritis: results from the BRAGGSS cohort

scientific article published on 31 May 2016

High-dose cyclophosphamide with stem cell rescue for severe rheumatoid arthritis: Short-term efficacy correlates with reduction of macroscopic and histologic synovitis

article

Human CD4(+)CD25(+) cells: a naturally occurring population of regulatory T cells.

scientific article

Humanised monoclonal antibody therapy for rheumatoid arthritis

scientific article published in The Lancet

IL-6-driven STAT signalling in circulating CD4+ lymphocytes is a marker for early anticitrullinated peptide antibody-negative rheumatoid arthritis

scientific article published on 3 February 2015

Immune reconstitution 20 years after treatment with alemtuzumab in a rheumatoid arthritis cohort: implications for lymphocyte depleting therapies

scientific article published on 20 December 2016

Immunity 12 years after alemtuzumab in RA: CD5⁺ B-cell depletion, thymus-dependent T-cell reconstitution and normal vaccine responses.

scientific article published on 24 March 2012

Immunotherapy of rheumatoid arthritis.

scientific article published in May 1992

Impact of inadequate adherence on response to subcutaneously administered anti-tumour necrosis factor drugs: results from the Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate cohort

scientific article

Impact of psychological factors on subjective disease activity assessments in patients with severe rheumatoid arthritis

scientific article

In search of pathobiological endotypes: a systems approach to early rheumatoid arthritis

scientific article published on 27 May 2020

Incidence of corneal melting in association with systemic disease in the Yorkshire Region, 1995-7

scientific article

Inhibition of macropinocytosis blocks antigen presentation of type II collagen in vitro and in vivo in HLA-DR1 transgenic mice.

scientific article published on January 2006

Integrated safety in tocilizumab clinical trials

scientific article published in September 2011

Investigating CD11c expression as a potential genomic biomarker of response to TNF inhibitor biologics in whole blood rheumatoid arthritis samples

scientific article

Investigation of genetic variants within candidate genes of the TNFRSF1B signalling pathway on the response to anti-TNF agents in a UK cohort of rheumatoid arthritis patients.

scientific article published in April 2009

Investigation of rheumatoid arthritis susceptibility genes identifies association of AFF3 and CD226 variants with response to anti-tumour necrosis factor treatment

scientific article

LPS activation is required for migratory activity and antigen presentation by tolerogenic dendritic cells.

scientific article published on 6 November 2008

Latent class trajectory modelling of 2-components-DAS28 identifies multiple rheumatoid arthritis phenotypes of response to biologic disease modifying anti-rheumatic drugs

scientific article published on 31 May 2020

Lessons learnt from a discontinued randomised controlled trial: adalimumab injection compared with placebo for patients receiving physiotherapy treatment for sciatica (Subcutaneous Injection of Adalimumab Trial compared with Control: SCIATiC)

scientific article published on 31 July 2018

Let's not fool ourselves. In RA, the ACR/EULAR remission criteria are not perfect!

scientific article

Local bioactive tumour necrosis factor (TNF) in corneal allotransplantation

scientific article published on 01 October 2000

Long-term remission of intractable systemic vasculitis with monoclonal antibody therapy

scientific article published in The Lancet

Lost in space: design of experiments and scientific exploration in a Hogarth Universe

scientific article

Low-strength T-cell activation promotes Th17 responses.

scientific article

Management of rheumatoid arthritis in primary care—an educational need?

scientific article published on 16 August 2005

Mechanism of action of methotrexate in rheumatoid arthritis, and the search for biomarkers.

scientific article

Mechanism of first-dose cytokine-release syndrome by CAMPATH 1-H: involvement of CD16 (FcgammaRIII) and CD11a/CD18 (LFA-1) on NK cells

scientific article

Mesangial IgA Disease with Crescent Formation During Pregnancy: Postpartum Treatment with Immunosuppression

scientific article published on 01 January 1990

Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization

scientific article published in January 2017

Minimum information about tolerogenic antigen-presenting cells (MITAP): a first step towards reproducibility and standardisation of cellular therapies

scientific article

Monoclonal antibody therapy of chronic intraocular inflammation using Campath-1H.

scientific article published on November 1995

Morbidity and mortality in rheumatoid arthritis patients with prolonged therapy-induced lymphopenia: twelve-year outcomes

scientific article published on February 2008

Neutralizing tumor necrosis factor activity leads to remission in patients with refractory noninfectious posterior uveitis

scientific article published in June 2004

Novel immunotherapies for rheumatoid arthritis.

scientific article published on August 2013

Novel therapies for immune-mediated inflammatory diseases: What can we learn from their use in rheumatoid arthritis, spondyloarthritis, systemic lupus erythematosus, psoriasis, Crohn's disease and ulcerative colitis?

scientific article published in August 2017

Overexpression of transcripts containing LINE-1 in the synovia of patients with rheumatoid arthritis.

scientific article published on July 2003

Pathophysiology of rheumatoid arthritis

scientific article published on May 2011

Patient and researcher perspectives on facilitating patient and public involvement in rheumatology research

scientific article published on 16 December 2016

Pharmacogenetics of TNF inhibitor response in rheumatoid arthritis utilizing the two-component disease activity score

scientific article published on 30 October 2020

Phenotypic and Transcriptomic Analysis of Peripheral Blood Plasmacytoid and Conventional Dendritic Cells in Early Drug Naïve Rheumatoid Arthritis.

scientific article published on 9 May 2018

Polymorphisms spanning the TNFR2 and TACE genes do not contribute towards variable anti-TNF treatment response.

scientific article published in May 2010

Predicting persistent inflammatory arthritis amongst early arthritis clinic patients in the UK: is musculoskeletal ultrasound required?

scientific article published on January 2013

Pregnancy Outcomes in the Tofacitinib Safety Databases for Rheumatoid Arthritis and Psoriasis.

scientific article published on 09 June 2016

Prevalence and diagnostic outcome relating to vitamin D deficiency in new patients presenting to an early arthritis clinic over 12 months

scientific article published on 24 June 2011

Prevention of immune-mediated corneal graft destruction with the anti-lymphocyte monoclonal antibody, CAMPATH-1H

scientific article published on 01 January 1995

Previously reported PDE3A-SLCO1C1 genetic variant does not correlate with anti-TNF response in a large UK rheumatoid arthritis cohort

scientific article published on 16 May 2016

Profound invariant natural killer T-cell deficiency in inflammatory arthritis.

scientific article published on 5 May 2010

Progression-seeking bias and rational optimism in research and development

scientific article

Prospective study of anti-tumour necrosis factor receptor superfamily 1B fusion protein, and case study of anti-tumour necrosis factor receptor superfamily 1A fusion protein, in tumour necrosis factor receptor associated periodic syndrome (TRAPS): c

scientific article published on February 2003

Prospects for therapeutic tolerance in humans

scientific article

R&D productivity rides again?

scientific article

RITPBC: B-cell depleting therapy (rituximab) as a treatment for fatigue in primary biliary cirrhosis: study protocol for a randomised controlled trial

scientific article

Real-time PCR based on SYBR-Green I fluorescence: an alternative to the TaqMan assay for a relative quantification of gene rearrangements, gene amplifications and micro gene deletions

scientific article

Regulatory T cells and autoimmunity

scientific article published on July 2009

Replication of association of the PTPRC gene with response to anti-tumor necrosis factor therapy in a large UK cohort

scientific article

Retrospective analysis of the role of serum vitamin D in early rheumatic disease

scientific article published on 17 November 2014

Rheumatoid arthritis response to treatment across IgG1 allotype - anti-TNF incompatibility: a case-only study

scientific article published on 18 March 2015

Rheumatoid arthritis risk allele PTPRC is also associated with response to anti-tumor necrosis factor alpha therapy

scientific article published on July 2010

Rheumatoid arthritis synovial T cells regulate transcription of several genes associated with antigen-induced anergy

scientific article

Rheumatoid arthritis: an evolutionary force in biologics

scientific article

Rheumatoid arthritis: from palliation to remission in two decades

scientific article published on December 2014

Rheumatology Conference Highlights

Robust optimization of SWATH-MS workflow for human blood serum proteome analysis using a quality by design approach

scientific article published on 12 August 2021

Safety, tolerability, pharmacokinetics, pharmacodynamics and efficacy of the monoclonal antibody ASK8007 blocking osteopontin in patients with rheumatoid arthritis: a randomised, placebo controlled, proof-of-concept study.

scientific article

Seronegative rheumatoid arthritis: pathogenetic and therapeutic aspects.

scientific article

Serotyping for an extended anti-citrullinated peptide autoantibody panel does not add value to CCP2 testing for diagnosing RA in an early undifferentiated arthritis cohort

scientific article published on 27 May 2011

Smart battles: immunosuppression versus immunomodulation in the inflammatory RMDs

scientific article published on 11 June 2020

Stem cell transplantation for autoimmune disorders. Immune reconstitution

scientific article published in June 2004

Subcutaneous Injection of Adalimumab Trial compared with Control (SCIATiC): a randomised controlled trial of adalimumab injection compared with placebo for patients receiving physiotherapy treatment for sciatica.

scientific article published in October 2017

Synovial CD4+ T-cell-derived GM-CSF supports the differentiation of an inflammatory dendritic cell population in rheumatoid arthritis.

scientific article

Synovial tissue research: a state-of-the-art review

scientific article

Synovial tissue research: a state-of-the-art review

scientific article published on 01 September 2017

T cell immunomodulation--the Holy Grail of therapeutic tolerance

scientific article published on 3 July 2007

T cell responses to a non-glycosylated epitope predominate in type II collagen-immunised HLA-DRB1*0101 transgenic mice

scientific article published on 17 November 2006

Targeting of tolerogenic dendritic cells towards heat shock proteins: a novel therapeutic strategy for autoimmune diseases?

scientific article published on 14 August 2017

Teaching examples for the design of experiments: geographical sensitivity and the self-fulfilling prophecy

scientific article published on 12 November 2015

Testing the role of vitamin D in response to antitumour necrosis factor α therapy in a UK cohort: a Mendelian randomisation approach

scientific article published on 9 December 2013

The 2013 BSR and BHPR guideline for the use of intravenous tocilizumab in the treatment of adult patients with rheumatoid arthritis

scholarly article by A. P. Malaviya et al published 16 September 2014 in Rheumatology

The 2013 BSR and BHPR guideline for the use of intravenous tocilizumab in the treatment of adult patients with rheumatoid arthritis.

scientific article published on 12 May 2014

The Darwin Awards: sex differences in idiotic behaviour

scientific article

The RA-MAP Consortium: a working model for academia-industry collaboration.

scientific article published on 7 December 2017

The changing face of rheumatoid arthritis: sustained remission for all?

scientific article

The clinical utility of a rule for predicting rheumatoid arthritis in patients with early undifferentiated arthritis: Comment on the article by van der Helm-van Mil et al

scientific article published on 01 March 2009

The impact of glycosylation on HLA-DR1-restricted T cell recognition of type II collagen in a mouse model.

scientific article published in February 2006

The interferon gene signature is increased in patients with early treatment-naive rheumatoid arthritis and predicts a poorer response to initial therapy.

scientific article published on 5 October 2017

The need for personalised medicine for rheumatoid arthritis

scientific article published on 10 November 2010

The predictive value of serum S100A9 and response to etanercept is not confirmed in a large UK rheumatoid arthritis cohort

scientific article

The relationship between pityriasis rubra pilaris and inflammatory arthritis: Case report and response of the arthritis to anti-tumor necrosis factor immunotherapy

article

The role of biosimilars in the treatment of rheumatic diseases

scientific article published on 19 December 2012

The value of synovial cytokine expression in predicting the clinical response to TNF antagonist therapy (infliximab).

scientific article published on 26 July 2008

Therapeutic T-cell manipulation in rheumatoid arthritis: past, present and future.

scientific article published on 25 May 2008

Therapeutic agents for patients with rheumatoid arthritis and an inadequate response to tumour necrosis factor-alpha antagonists

scientific article published on December 2009

Therapeutic effect of tolerogenic dendritic cells in established collagen-induced arthritis is associated with a reduction in Th17 responses

article

Thymic function and immune senescence in juvenile idiopathic arthritis: Comment on the article by Prelog et al

scientific article published on 01 January 2009

Tofacitinib in Combination With Nonbiologic Disease-Modifying Antirheumatic Drugs in Patients With Active Rheumatoid Arthritis

article

Tolerogenic dendritic cell therapy for rheumatoid arthritis: where are we now?

scientific article

Tolerogenic dendritic cells generated with dexamethasone and vitamin D3 regulate rheumatoid arthritis CD4+ T cells partly via transforming growth factor-β1.

scientific article published on 26 September 2016

Traceless Cleavage of Protein-Biotin Conjugates under Biologically Compatible Conditions

scientific article published on 05 June 2017

Transient increase in symptoms associated with cytokine release in patients with multiple sclerosis

scientific article published in February 1996

Translating cutting edge science into novel and effective therapies

scientific article published on 04 June 2010

Treating to re-establish tolerance in inflammatory arthritis - lessons from other diseases

scientific article published on August 2010

Treatment of stiff person syndrome with rituximab.

scientific article

Treg cells in rheumatoid arthritis: an update

scientific article published on September 2013

Tumour necrosis factor alpha blockade impairs dendritic cell survival and function in rheumatoid arthritis

scientific article published on 22 September 2009

Unique TCR beta-subunit variable gene haplotypes in Africans

scientific article

What can rheumatologists learn from translational cancer therapy?

scientific article published on January 2013

Why is it hard to terminate failing projects in pharmaceutical R&D?

scientific article published on 21 August 2015

Will treatment of rheumatoid arthritis with an IL-6R inhibitor help facilitate the 'age of remission'?

scientific article