List of works - Gerhard Wider

1H, 15N and 13C NMR assignments of the 434 repressor fragments 1-63 and 44-63 unfolded in 7 M urea.

scientific article published in June 1992

1H, 15N, 13C resonance assignment of the acyl carrier protein subunit of the Saccharomyces cerevisiae fatty acid synthase

3D 13C-15N-heteronuclear two-spin coherence spectroscopy for polypeptide backbone assignments in 13C-15N-double-labeled proteins.

scientific article published in January 1993

4D APSY-HBCB(CG)CDHD experiment for automated assignment of aromatic amino acid side chains in proteins

article

4D experiments measured with APSY for automated backbone resonance assignments of large proteins

scientific article

A Simple Experimental Scheme Using Pulsed Field Gradients for Coherence-Pathway Rejection and Solvent Suppression in Phase-Sensitive Heteronuclear Correlation Spectra

article by Gerhard Wider & Kurt Wüthrich published October 1993 in Journal of magnetic resonance. Series B

A heteronuclear three-dimensional NMR experiment for measurements of small heteronuclear coupling constants in biological macromolecules

scholarly article by Gerhard Wider et al published November 1989 in Journal of Magnetic Resonance

APSY-NMR with proteins: practical aspects and backbone assignment

scientific article published on 8 October 2008

Activity of Tumor Necrosis Factor α Is Modulated by Dynamic Conformational Rearrangements.

scientific article published in December 2017

Assignment of the 1H nuclear magnetic resonance spectrum of the proteinase inhibitor IIA from bull seminal plasma by two-dimensional nuclear magnetic resonance at 500 MHz

scientific article published on 01 June 1983

Assignment of the 1H nuclear magnetic resonance spectrum of the trypsin inhibitor E from Dendroaspis polylepis polylepis

scientific article published on 01 August 1982

Attenuated T2 relaxation by mutual cancellation of dipole-dipole coupling and chemical shift anisotropy indicates an avenue to NMR structures of very large biological macromolecules in solution

scientific article

Automated NMR assignment of protein side chain resonances using automated projection spectroscopy (APSY).

scientific article published on 19 August 2008

Automated NMR resonance assignment strategy for RNA via the phosphodiester backbone based on high-dimensional through-bond APSY experiments.

scientific article published on 27 April 2014

Automated Projection Spectroscopy and Its Applications ⬇️

scientific article published on January 1, 2012

Automated projection spectroscopy (APSY) for the assignment of NMR resonances of biological macromolecules

scientific article published in January 2012

Automated projection spectroscopy (APSY).

scientific article

Automated resonance assignment of proteins: 6D APSY-NMR.

scientific article

Comparison of the NMR solution structure with the X-ray crystal structure of the activation domain from procarboxypeptidase B.

scientific article published in January 1992

Computer vision-based automated peak picking applied to protein NMR spectra

scientific article

Concentration measurements by PULCON using X-filtered or 2D NMR spectra

Conformation of glucagon in a lipid-water interphase by 1H nuclear magnetic resonance

scientific article

Copsin, a novel peptide-based fungal antibiotic interfering with the peptidoglycan synthesis.

scientific article

Cyclosporin A-cyclophilin complex formation. A model based on X-ray and NMR data

scientific article published on April 6, 1992

Determination of the Dihedral Angle ψ Based onJCoupling Measurements in15N/13C-Labeled Proteins

scientific article published in 1998

Determination of the NMR solution structure of the cyclophilin A-cyclosporin A complex

scientific article

Deuterium Relaxation in a Uniformly15N-Labeled Homeodomain and Its DNA Complex1

scientific article published in 1997

Diffusion Filters for Separation of Solvent−Protein and Protein−Protein Nuclear Overhauser Effects (HYDRA)

scientific article published in 1996

Direct NMR observation of a substrate protein bound to the chaperonin GroEL.

scientific article

Direct monitoring of protein–protein inhibition using nano electrospray ionization mass spectrometry

scholarly article by Dragana Cubrilovic et al published 2014 in Chemical Science

Dissection of heteronuclear NMR experiments for studies of magnetization transfer efficiencies

scientific article published on 01 November 2003

Effective rotational correlation times of proteins from NMR relaxation interference.

scientific article published on 26 September 2005

Elimination of baseline artifacts in NMR spectra by oversampling

article published in 1990

Enabling adoption of 2D-NMR for the higher order structure assessment of monoclonal antibody therapeutics

scientific article published on 22 December 2018

Exchange rates of internal water molecules in proteins measured using pulsed field gradients

scientific article published in 1995

Figure of Merit and Cycling Sidebands in Adiabatic Decoupling

Guest editor's foreword: NMR of proteins in solution

High-resolution nuclear magnetic resonance applied to biophysics and molecular biology: highlights and challenges

scholarly article by Gerhard Wider published in March 2002

Homonuclear two-dimensional 1H NMR of proteins. Experimental procedures

Hormone-receptor interactions: a study of the binding of hormone-substituted tobacco mosaic virus to membrane vesicles by dynamic light scattering and by transient electric bi-refringence

Improved sensitivity and coherence selection for [15N,1H]-TROSY elements in triple resonance experiments

scientific article published on 01 October 1999

Improvement of 2D NOE and 2D correlated spectra by symmetrization

Interactions of the Acyl Chain with the Saccharomyces cerevisiae Acyl Carrier Protein

scientific article published in 2015

Interactions with hydrophobic clusters in the urea-unfolded membrane protein OmpX.

scientific article published in January 2008

Intramolecular donor strand complementation in the E. coli type 1 pilus subunit FimA explains the existence of FimA monomers as off-pathway products of pilus assembly that inhibit host cell apoptosis

scientific article

Lipid-protein interactions in DHPC micelles containing the integral membrane protein OmpX investigated by NMR spectroscopy

scientific article

Managing the solvent water polarization to obtain improved NMR spectra of large molecular structures

scientific article

Measuring Protein Concentrations by NMR Spectroscopy

scientific article published in 2006

Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5

scientific article published on 17 July 2019

Membrane protein-lipid interactions in mixed micelles studied by NMR spectroscopy with the use of paramagnetic reagents

scientific article published in April 2004

Monitoring NMR spectrometer performance during data accumulation for macromolecular structure determination.

scientific article published on March 1996

NMR Assignment and Secondary Structure Determination of an Octameric 110 kDa Protein Using TROSY in Triple Resonance Experiments

scientific article published in 2000

NMR characterization of the full‐length recombinant murine prion protein, mPrP(23–231) ⬇️

scientific article published on August 18, 1997

NMR determination of residual structure in a urea-denatured protein, the 434-repressor

scientific article published in Science

NMR experiments for resonance assignments of 13C, 15N doubly-labeled flexible polypeptides: application to the human prion protein hPrP(23-230)

scientific article published on 01 February 2000

NMR solution structure of the human prion protein

scientific article

NMR spectroscopy of large molecules and multimolecular assemblies in solution.

scientific article

NMR structure of a variant 434 repressor DNA-binding domain devoid of hydroxyl groups

scientific article published in July 2004

NMR structure of the apoptosis- and inflammation-related NALP1 pyrin domain

scientific article

NMR structure of the integral membrane protein OmpX.

scientific article

NMR structure of the mouse prion protein domain PrP(121-231)

scientific article

NMR structure of the sea urchin (Strongylocentrotus purpuratus) metallothionein MTA

scientific article

NMR structures of salt-refolded forms of the 434-repressor DNA-binding domain in 6 M urea

scientific article

NMR structures of the micelle-bound polypeptide hormone glucagon

article

NMR studies of the hydration of biological macromolecules

scholarly article by Kurt Wüthrich et al published 1996 in Faraday Discussions

NMR techniques used with very large biological macromolecules in solution

scientific article

NMR-derived dynamic aspects of N-type inactivation of a Kv channel suggest a transient interaction with the T1 domain

scientific article published on February 2006

Pancreatic Procarboxypeptidases: Their Activation Processes Related to the Structural Features of the Zymogens and Activation Segments

article

Phase-Sensitive Spectra in a Single Scan with Coherence Selection by Pulsed Field Gradients

Polarization transfer by cross-correlated relaxation in solution NMR with very large molecules

scientific article

Posttranslational Modifications of Intact Proteins Detected by NMR Spectroscopy: Application to Glycosylation

scientific article published on 29 April 2015

Prion protein NMR structure and familial human spongiform encephalopathies

scientific article

Prion protein structural features indicate possible relations to signal peptidases ⬇️

scientific article published on April 24, 1998

Processing of multi-dimensional NMR data with the new software PROSA

scholarly article by Peter Güntert et al published November 1992 in Journal of Biomolecular NMR

Projected [(1)H, (15)N]-HMQC-[ (1)H, (1)H]-NOESY for large molecular systems: application to a 121 kDa protein-DNA complex

scientific article published on 30 January 2008

Proton-proton Overhauser NMR spectroscopy with polypeptide chains in large structures

scientific article

Proton-proton Overhauser effects of receptor-bound cyclosporin A observed with the use of a heteronuclear-resolved half-filter experiment

article by Gerhard Wider et al published June 1991 in Journal of the American Chemical Society

Real-time imaging of the spatial distribution of rf-heating in NMR samples during broadband decoupling

scientific article published on 3 May 2007

Recombinant full-length murine prion protein, mPrP(23-231): purification and spectroscopic characterization.

scientific article published in August 1997

Reduced dimensionality in triple-resonance NMR experiments

scientific article published in 1993

Salt-stabilized globular protein structure in 7 M aqueous urea solution.

scientific article

Self-Compensating Pulsed Magnetic-Field Gradients for Short Recovery Times

Sensitivity Gain by Simultaneous Acquisition of Two Coherence Pathways: The HNCA+ Experiment

Sequence-Corrected 15N "Random Coil" Chemical Shifts

article by Daniel Braun et al published September 1994 in Journal of the American Chemical Society

Sequence-specific resonance assignment of soluble nonglobular proteins by 7D APSY-NMR spectroscopy

scientific article published on 11 August 2007

Sequential Individual Resonance Assignments in the 1H Nuclear-Magnetic-Resonance Spectrum of Cardiotoxin VII 2 from Naja mossambica mossambica

scientific article published on 01 February 1983

Sequential assignments for the hydrogen and phosphorus-31 atoms in the backbone of oligonucleotides by two-dimensional nuclear magnetic resonance

scientific article published in 1983

Sequential resonance assignments as a basis for determination of spatial protein structures by high resolution proton nuclear magnetic resonance

scientific article published on 01 March 1982

Sequential resonance assignments in protein 1H nuclear magnetic resonance spectra. Glucagon bound to perdeuterated dodecylphosphocholine micelles.

scientific article published on March 1982

Side chain NMR assignments in the membrane protein OmpX reconstituted in DHPC micelles

scientific article published in August 2002

Single Transition-to-single Transition Polarization Transfer (ST2-PT) in [15N,1H]-TROSY.

scientific article

Solvent Magnetization Artifacts in High-Field NMR Studies of Macromolecular Hydration

scholarly article by Alexander G. Sobol et al published February 1998 in Journal of Magnetic Resonance

Solvent suppression using a spin lock in 2D and 3D NMR spectroscopy with H2O solutions

article published in 1989

Stereospecific assignments of the isopropyl methyl groups of the membrane protein OmpX in DHPC micelles

scientific article published in December 2003

Strategy for automated NMR resonance assignment of RNA: application to 48-nucleotide K10.

scientific article published on 5 June 2014

Strong spin-spin coupling in the two-dimensional J-resolved 360-MHz 1H NMR spectra of the common amino acids

Structural Analysis of the Conserved Ubiquitin-binding Motifs (UBMs) of the Translesion Polymerase iota in Complex with Ubiquitin

scientific article

Structural biology of prion proteins

Structure, folding and stability of FimA, the main structural subunit of type 1 pili from uropathogenic Escherichia coli strains

scientific article

Structure-function analysis of the endoplasmic reticulum oxidoreductase TMX3 reveals interdomain stabilization of the N-terminal redox-active domain.

scientific article

Studies of slow conformational equilibria in macromolecules by exchange of heteronuclear longitudinal 2-spin-order in a 2D difference correlation experiment

scholarly article by Gerhard Wider et al published May 1991 in Journal of Biomolecular NMR

Sugar-to-base correlation in nucleic acids with a 5D APSY-HCNCH or two 3D APSY-HCN experiments

article by Barbara Krähenbühl et al published 4 December 2011 in Journal of Biomolecular NMR

Suppression of Cycling Sidebands Using Bi-level Adiabatic Decoupling

Suppression of the solvent resonance in 2D NMR spectra of proteins in H2O solution

TROSY in NMR studies of the structure and function of large biological macromolecules

scientific article published on October 2003

TROSY in triple-resonance experiments: new perspectives for sequential NMR assignment of large proteins

scientific article published on November 1998

TROSY-type Triple-Resonance Experiments for Sequential NMR Assignments of Large Proteins

article by Michael Salzmann et al published February 1999 in Journal of the American Chemical Society

Technical aspects of NMR Spectroscopy with biological macromolecules and studies of hydration in solution

scholarly article by Gerhard Wider published May 1998 in Progress in Nuclear Magnetic Resonance Spectroscopy

The 3D NOESY-[(1)H,(15)N,(1)H]-ZQ-TROSY NMR experiment with diagonal peak suppression

scientific article

The NMR solution structure of the non-classical homeodomain from the rat liver LFB1/HNF1 transcription factor

scientific article

The RING Domain of the Scaffold Protein Ste5 Adopts a Molten Globular Character with High Thermal and Chemical Stability

Three-dimensional NMR structure of a self-folding domain of the prion protein PrP(121–231)

scientific article published on 01 July 1997

Transverse Relaxation-Optimized Spectroscopy (TROSY) for NMR Studies of Aromatic Spin Systems in13C-Labeled Proteins

scientific article published in 1998

Transverse relaxation-optimized NMR spectroscopy with biomacromolecular structures in solution

Ubiquitin-binding domains in Y-family polymerases regulate translesion synthesis

scientific article

Use of a double half-filter in two-dimensional proton NMR studies of receptor-bound cyclosporin

article by Gerhard Wider et al published November 1990 in Journal of the American Chemical Society

X-relayed 1H-1H correlated spectroscopy

[13C]-constant-time [15N,1H]-TROSY-HNCA for sequential assignments of large proteins

scientific article published on 01 May 1999

List of works by Gerhard Wider

1H, 15N and 13C NMR assignments of the 434 repressor fragments 1-63 and 44-63 unfolded in 7 M urea.

1H, 15N, 13C resonance assignment of the acyl carrier protein subunit of the Saccharomyces cerevisiae fatty acid synthase

3D 13C-15N-heteronuclear two-spin coherence spectroscopy for polypeptide backbone assignments in 13C-15N-double-labeled proteins.

4D APSY-HBCB(CG)CDHD experiment for automated assignment of aromatic amino acid side chains in proteins

4D experiments measured with APSY for automated backbone resonance assignments of large proteins

A Simple Experimental Scheme Using Pulsed Field Gradients for Coherence-Pathway Rejection and Solvent Suppression in Phase-Sensitive Heteronuclear Correlation Spectra

A heteronuclear three-dimensional NMR experiment for measurements of small heteronuclear coupling constants in biological macromolecules

APSY-NMR with proteins: practical aspects and backbone assignment

Activity of Tumor Necrosis Factor α Is Modulated by Dynamic Conformational Rearrangements.

Assignment of the 1H nuclear magnetic resonance spectrum of the proteinase inhibitor IIA from bull seminal plasma by two-dimensional nuclear magnetic resonance at 500 MHz

Assignment of the 1H nuclear magnetic resonance spectrum of the trypsin inhibitor E from Dendroaspis polylepis polylepis

Attenuated T2 relaxation by mutual cancellation of dipole-dipole coupling and chemical shift anisotropy indicates an avenue to NMR structures of very large biological macromolecules in solution

Automated NMR assignment of protein side chain resonances using automated projection spectroscopy (APSY).

Automated NMR resonance assignment strategy for RNA via the phosphodiester backbone based on high-dimensional through-bond APSY experiments.

Automated Projection Spectroscopy and Its Applications ⬇️

Automated projection spectroscopy (APSY) for the assignment of NMR resonances of biological macromolecules

Automated projection spectroscopy (APSY).

Automated resonance assignment of proteins: 6D APSY-NMR.

Comparison of the NMR solution structure with the X-ray crystal structure of the activation domain from procarboxypeptidase B.

Computer vision-based automated peak picking applied to protein NMR spectra

Concentration measurements by PULCON using X-filtered or 2D NMR spectra

Conformation of glucagon in a lipid-water interphase by 1H nuclear magnetic resonance

Copsin, a novel peptide-based fungal antibiotic interfering with the peptidoglycan synthesis.

Cyclosporin A-cyclophilin complex formation. A model based on X-ray and NMR data

Determination of the Dihedral Angle ψ Based onJCoupling Measurements in15N/13C-Labeled Proteins

Determination of the NMR solution structure of the cyclophilin A-cyclosporin A complex

Deuterium Relaxation in a Uniformly15N-Labeled Homeodomain and Its DNA Complex1

Diffusion Filters for Separation of Solvent−Protein and Protein−Protein Nuclear Overhauser Effects (HYDRA)

Direct NMR observation of a substrate protein bound to the chaperonin GroEL.

Direct monitoring of protein–protein inhibition using nano electrospray ionization mass spectrometry

Dissection of heteronuclear NMR experiments for studies of magnetization transfer efficiencies

Effective rotational correlation times of proteins from NMR relaxation interference.

Elimination of baseline artifacts in NMR spectra by oversampling

Enabling adoption of 2D-NMR for the higher order structure assessment of monoclonal antibody therapeutics

Exchange rates of internal water molecules in proteins measured using pulsed field gradients

Figure of Merit and Cycling Sidebands in Adiabatic Decoupling

Guest editor's foreword: NMR of proteins in solution

High-resolution nuclear magnetic resonance applied to biophysics and molecular biology: highlights and challenges

Homonuclear two-dimensional 1H NMR of proteins. Experimental procedures

Hormone-receptor interactions: a study of the binding of hormone-substituted tobacco mosaic virus to membrane vesicles by dynamic light scattering and by transient electric bi-refringence

Improved sensitivity and coherence selection for [15N,1H]-TROSY elements in triple resonance experiments

Improvement of 2D NOE and 2D correlated spectra by symmetrization

Interactions of the Acyl Chain with the Saccharomyces cerevisiae Acyl Carrier Protein

Interactions with hydrophobic clusters in the urea-unfolded membrane protein OmpX.

Intramolecular donor strand complementation in the E. coli type 1 pilus subunit FimA explains the existence of FimA monomers as off-pathway products of pilus assembly that inhibit host cell apoptosis

Lipid-protein interactions in DHPC micelles containing the integral membrane protein OmpX investigated by NMR spectroscopy

Managing the solvent water polarization to obtain improved NMR spectra of large molecular structures

Measuring Protein Concentrations by NMR Spectroscopy

Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5

Membrane protein-lipid interactions in mixed micelles studied by NMR spectroscopy with the use of paramagnetic reagents

Monitoring NMR spectrometer performance during data accumulation for macromolecular structure determination.

NMR Assignment and Secondary Structure Determination of an Octameric 110 kDa Protein Using TROSY in Triple Resonance Experiments

NMR characterization of the full‐length recombinant murine prion protein, mPrP(23–231) ⬇️

NMR determination of residual structure in a urea-denatured protein, the 434-repressor

NMR experiments for resonance assignments of 13C, 15N doubly-labeled flexible polypeptides: application to the human prion protein hPrP(23-230)

NMR solution structure of the human prion protein

NMR spectroscopy of large molecules and multimolecular assemblies in solution.

NMR structure of a variant 434 repressor DNA-binding domain devoid of hydroxyl groups

NMR structure of the apoptosis- and inflammation-related NALP1 pyrin domain

NMR structure of the integral membrane protein OmpX.

NMR structure of the mouse prion protein domain PrP(121-231)

NMR structure of the sea urchin (Strongylocentrotus purpuratus) metallothionein MTA

NMR structures of salt-refolded forms of the 434-repressor DNA-binding domain in 6 M urea

NMR structures of the micelle-bound polypeptide hormone glucagon

NMR studies of the hydration of biological macromolecules

NMR techniques used with very large biological macromolecules in solution

NMR-derived dynamic aspects of N-type inactivation of a Kv channel suggest a transient interaction with the T1 domain

Pancreatic Procarboxypeptidases: Their Activation Processes Related to the Structural Features of the Zymogens and Activation Segments

Phase-Sensitive Spectra in a Single Scan with Coherence Selection by Pulsed Field Gradients

Polarization transfer by cross-correlated relaxation in solution NMR with very large molecules

Posttranslational Modifications of Intact Proteins Detected by NMR Spectroscopy: Application to Glycosylation

Prion protein NMR structure and familial human spongiform encephalopathies

Prion protein structural features indicate possible relations to signal peptidases ⬇️

Processing of multi-dimensional NMR data with the new software PROSA

Projected [(1)H, (15)N]-HMQC-[ (1)H, (1)H]-NOESY for large molecular systems: application to a 121 kDa protein-DNA complex

Proton-proton Overhauser NMR spectroscopy with polypeptide chains in large structures

Proton-proton Overhauser effects of receptor-bound cyclosporin A observed with the use of a heteronuclear-resolved half-filter experiment

Real-time imaging of the spatial distribution of rf-heating in NMR samples during broadband decoupling

Recombinant full-length murine prion protein, mPrP(23-231): purification and spectroscopic characterization.