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List of works by Claudia Simoes-Pires

5-Benzylidene-hydantoin is a new scaffold for SIRT inhibition: From virtual screening to activity assays

scientific article published on 12 January 2016

A Rational Approach for the Identification of Non-Hydroxamate HDAC6-Selective Inhibitors

scientific article

Alkaloids from psychotria target sirtuins: in silico and in vitro interaction studies

scientific article published on 03 December 2014

Anti-inflammatory, antimicrobial and antioxidant activities of Diospyros bipindensis (Gürke) extracts and its main constituents.

scientific article published on 18 January 2013

Aurones as histone deacetylase inhibitors: identification of key features

scientific article

Biphenyl-4-yl-acrylohydroxamic acids: Identification of a novel indolyl-substituted HDAC inhibitor with antitumor activity

scientific article published on 3 February 2016

Cancer chemopreventive diterpenes from Salvia corrugata

scientific article published on 10 October 2013

Cell-based multi-substrate assay coupled to UHPLC-ESI-MS/MS for a quick identification of class-specific HDAC inhibitors

scientific article published on 05 May 2016

Characterization of Lignanamides from Hemp (Cannabis sativa L.) Seed and Their Antioxidant and Acetylcholinesterase Inhibitory Activities

scientific article published on 19 November 2015

Collateral sensitivity of resistant MRP1-overexpressing cells to flavonoids and derivatives through GSH efflux

scientific article

Cross metathesis with hydroxamate and benzamide BOC-protected alkenes to access HDAC inhibitors and their biological evaluation highlighted intrinsic activity of BOC-protected dihydroxamates

scientific article published on 11 November 2015

Detecting, quantifying, and discriminating the mechanism of mosaic chromosomal aneuploidies using MAD-seq

scientific article published on 17 May 2018

Ellagic acid derivatives from Syzygium cumini stem bark: investigation of their antiplasmodial activity.

scientific article

Functional genetic variants can mediate their regulatory effects through alteration of transcription factor binding

scientific article published on 02 August 2019

HDAC6 as a target for neurodegenerative diseases: what makes it different from the other HDACs?

scientific article

High-efficiency genomic editing in Epstein-Barr virus-transformed lymphoblastoid B cells using a single-stranded donor oligonucleotide strategy

scientific article published on 14 August 2019

How to increase the safety and efficacy of compounds against neurodegeneration? A multifunctional approach.

scientific article published on January 2012

Hydroxyl Ketone-Based Histone Deacetylase Inhibitors To Gain Insight into Class I HDAC Selectivity versus That of HDAC6.

scientific article published on 20 April 2017

Indole alkaloids of Psychotria as multifunctional cholinesterases and monoamine oxidases inhibitors

scientific article published on 19 December 2012

Isolation and on-line identification of antioxidant compounds from three Baccharis species by HPLC-UV-MS/MS with post-column derivatisation

scientific article published on 01 September 2005

Monoamine oxidase inhibition by monoterpene indole alkaloids and fractions obtained from Psychotria suterella and Psychotria laciniata.

scientific article

Normal phase HPLC-based activity profiling of non-polar crude plant extracts - acetylcholinesterase inhibiting guttiferones from Montrouziera cauliflora as a case study

scientific article published on 26 April 2016

Novel histone deacetylase 6 (HDAC6) selective inhibitors: a patent evaluation (WO2014181137).

scientific article published on 16 January 2017

Prevention of False-Positive Results: Development of an HPTLC Autographic Assay for the Detection of Natural Tyrosinase Inhibitors

scientific article published on 28 July 2015

Protective effect of Chresta martii extract against indomethacin-induced gastric lesions in mice.

scientific article published on 27 March 2012

Reverse pharmacology for developing an anti-malarial phytomedicine. The example of Argemone mexicana

scientific article

Simultaneous Measurement of HDAC1 and HDAC6 Activity in HeLa Cells Using UHPLC-MS.

scientific article published on 10 August 2017

Study of leaf metabolome modifications induced by UV-C radiations in representative Vitis, Cissus and Cannabis species by LC-MS based metabolomics and antioxidant assays.

scientific article

Synthesis of a selective HDAC6 inhibitor active in neuroblasts

scientific article published on 07 September 2016

Synthesis of an Uncharged Tetra-cyclopeptide Acting as a Transmembrane Carrier: Enhanced Cellular and Nuclear Uptake

scientific article published on 20 January 2017

UHPLC-MS-based HDAC Assay Applied to Bio-guided Microfractionation of Fungal Extracts

scientific article published on 5 December 2016

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