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List of works by Giorgio Trinchieri

A dysbiotic microbiome triggers T17 cells to mediate oral mucosal immunopathology in mice and humans

scientific article published on 01 October 2018

A systematic approach to biomarker discovery; preamble to "the iSBTc-FDA taskforce on immunotherapy biomarkers".

scientific article

A type I interferon autocrine-paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells.

scientific article

Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth

scientific article published on November 2012

Alloantigen-presenting plasmacytoid dendritic cells mediate tolerance to vascularized grafts.

scientific article

An Interleukin-23-Interleukin-22 Axis Regulates Intestinal Microbial Homeostasis to Protect from Diet-Induced Atherosclerosis

scientific article published on 30 October 2018

Are dendritic cells afraid of commitment?

scientific article published in December 2004

At 17, in-10's passion need not inflame

scientific article published on 01 April 2011

Attenuation of immune-mediated bone marrow damage in conventionally housed mice

scientific article published on 02 January 2020

Author Correction: Interaction between the microbiome and TP53 in human lung cancer

scientific article published on 20 February 2020

Author Correction: Requirements for the differentiation of innate T-bethigh memory-phenotype CD4+ T lymphocytes under steady state

scientific article published on 10 September 2020

Bone-Marrow-Resident NK Cells Prime Monocytes for Regulatory Function during Infection

scientific article published on 9 June 2015

CCR6/CCR10-mediated plasmacytoid dendritic cell recruitment to inflamed epithelia after instruction in lymphoid tissues

scientific article published on 21 September 2011

CD85j (leukocyte Ig-like receptor-1/Ig-like transcript 2) inhibits human osteoclast-associated receptor-mediated activation of human dendritic cells

scientific article

Can we harness the microbiota to enhance the efficacy of cancer immunotherapy?

scientific article published on 13 July 2020

Cancer and inflammation: promise for biologic therapy.

scientific article

Cancer classification using the Immunoscore: a worldwide task force

scientific article

Cell depletion in mice that express diphtheria toxin receptor under the control of SiglecH encompasses more than plasmacytoid dendritic cells

scientific article

Cell proliferation and survival induced by Toll-like receptors is antagonized by type I IFNs

scholarly article

Cell-Type-Specific Responses to Interleukin-1 Control Microbial Invasion and Tumor-Elicited Inflammation in Colorectal Cancer

scientific article published on 01 January 2019

Commensal bacteria control cancer response to therapy by modulating the tumor microenvironment.

scientific article

Compartmentalized control of skin immunity by resident commensals

scientific article

Conventional Co-Housing Modulates Murine Gut Microbiota and Hematopoietic Gene Expression

scientific article published on 26 August 2020

Cooperation of Toll-like receptor signals in innate immune defence

scientific article published on March 2007

Cord factor and peptidoglycan recapitulate the Th17-promoting adjuvant activity of mycobacteria through mincle/CARD9 signaling and the inflammasome

scientific article published on 29 April 2013

Correlation between Disease Severity and the Intestinal Microbiome in Mycobacterium tuberculosis-Infected Rhesus Macaques.

scientific article published on 4 June 2019

Differential regulation of interleukin 12 and interleukin 23 production in human dendritic cells

scientific article published on 19 May 2008

Differential responses of plasmacytoid dendritic cells to influenza virus and distinct viral pathogens

scientific article

Distinct and overlapping roles of interleukin-10 and CD25+ regulatory T cells in the inhibition of antitumor CD8 T-cell responses

scientific article published on 01 September 2005

Distinct contributions of cathelin-related antimicrobial peptide (CRAMP) derived from epithelial cells and macrophages to colon mucosal homeostasis

scientific article published on 26 October 2020

Double stranded RNA tricks melanoma cells into committing suicide.

scientific article

FAM3D is essential for colon homeostasis and host defense against inflammation associated carcinogenesis

scientific article published on 20 November 2020

Fc receptor gamma-chain activation via hOSCAR induces survival and maturation of dendritic cells and modulates Toll-like receptor responses

scientific article

Flexibility of mouse classical and plasmacytoid-derived dendritic cells in directing T helper type 1 and 2 cell development: dependency on antigen dose and differential toll-like receptor ligation ⬇️

scientific article

Future perspectives in melanoma research. Meeting report from the "Melanoma Bridge. Napoli, December 2nd-4th 2012".

scientific article published on 3 June 2013

Gut microbiome directs hepatocytes to recruit MDSC and promote cholangiocarcinoma

scientific article published on 15 December 2020

Gut microbiome-mediated bile acid metabolism regulates liver cancer via NKT cells

scientific article published in Science

Highlights of 10 years of immunology in Nature Reviews Immunology

scientific article published on 23 September 2011

Human NK cells prime inflammatory DC precursors to induce Tc17 differentiation

scientific article published on 01 August 2020

Human TLR10 is a functional receptor, expressed by B cells and plasmacytoid dendritic cells, which activates gene transcription through MyD88

scientific journal article

Human thymus contains IFN-α-producing CD11c–, myeloid CD11c+, and mature interdigitating dendritic cells

IFN-gamma and IL-12 differentially regulate CC-chemokine secretion and CCR5 expression in human T lymphocytes

scientific article published on 01 October 2002

IL-12 triggers a programmatic change in dysfunctional myeloid-derived cells within mouse tumors.

scientific article published on 7 November 2011

IL-1R-MyD88 signaling in keratinocyte transformation and carcinogenesis

scientific article

Ikaros is required for plasmacytoid dendritic cell differentiation

scientific article published on 15 August 2006

Immunologic and therapeutic synergy of IL-27 and IL-2: enhancement of T cell sensitization, tumor-specific CTL reactivity and complete regression of disseminated neuroblastoma metastases in the liver and bone marrow

scientific article published on April 2009

In vivo manipulation of dendritic cell migration and activation to elicit antitumour immunity.

scientific article published on January 2004

Infection trains the host for microbiota-enhanced resistance to pathogens

scientific article published on 15 January 2021

Influence of gut microbiome on mucosal immune activation and SHIV viral transmission in naive macaques

article

Interaction between conventional dendritic cells and natural killer cells is integral to the activation of effective antiviral immunity.

scientific article

Interaction between the microbiome and TP53 in human lung cancer

scientific article published on 24 August 2018

Interferon alpha/beta and interleukin 12 responses to viral infections: pathways regulating dendritic cell cytokine expression in vivo

scientific article

Interferon-dependent IL-10 production by Tregs limits tumor Th17 inflammation

scientific article

Interleukin-1 and interferon-γ orchestrate β-glucan-activated human dendritic cell programming via IκB-ζ modulation

scientific article

Interleukin-12 in anti-tumor immunity and immunotherapy.

scientific article

Interleukin-2 inhibits FMS-like tyrosine kinase 3 receptor ligand (flt3L)-dependent development and function of conventional and plasmacytoid dendritic cells ⬇️

scientific article published on January 24, 2011

Intraluminal containment of commensal outgrowth in the gut during infection-induced dysbiosis

scientific article published on September 2013

LAB/NTAL facilitates fungal/PAMP-induced IL-12 and IFN-γ production by repressing β-catenin activation in dendritic cells

scientific article

Laboratory mice born to wild mice have natural microbiota and model human immune responses

scientific article published on 01 August 2019

Ligand and cytokine dependence of the immunosuppressive pathway of tryptophan catabolism in plasmacytoid dendritic cells.

scientific article published on 19 September 2005

Ligation of the FcR gamma chain-associated human osteoclast-associated receptor enhances the proinflammatory responses of human monocytes and neutrophils

scientific article

Longitudinal profiling reveals a persistent intestinal dysbiosis triggered by conventional anti-tuberculosis therapy.

scientific article

MAVS deficiency induces gut dysbiotic microbiota conferring a proallergic phenotype

article published in the Proceedings of the National Academy of Sciences of the United States of America

MHC Class II Antigen Presentation by the Intestinal Epithelium Initiates Graft-versus-Host Disease and Is Influenced by the Microbiota

scientific article published on 18 September 2019

Macrophages and myeloid dendritic cells, but not plasmacytoid dendritic cells, produce IL-10 in response to MyD88- and TRIF-dependent TLR signals, and TLR-independent signals.

scientific article published in December 2006

Microbial DNA signature in plasma enables cancer diagnosis

scientific article published on 18 May 2020

Microbiota-Dependent Sequelae of Acute Infection Compromise Tissue-Specific Immunity

scientific article published on October 2015

Molecular pathways: toll-like receptors in the tumor microenvironment--poor prognosis or new therapeutic opportunity.

scientific article published on 27 December 2012

Mouse strain differences in plasmacytoid dendritic cell frequency and function revealed by a novel monoclonal antibody

scientific article published on 01 December 2003

Mouse type I IFN-producing cells are immature APCs with plasmacytoid morphology

article by Carine Asselin-Paturel et al published 19 November 2001 in Nature Immunology

Mucosal vaccine efficacy against intrarectal SHIV is independent of anti-Env antibody response

article

Multi-omics: Differential expression of IFN-γ results in distinctive mechanistic features linking chronic inflammation, gut dysbiosis, and autoimmune diseases

scientific article published on 24 March 2020

Murine plasmacytoid dendritic cells initiate the immunosuppressive pathway of tryptophan catabolism in response to CD200 receptor engagement

scientific article published on September 2004

MyD88 and its divergent toll in carcinogenesis.

scientific article published on 07 May 2013

MyD88-dependent and -independent murine cytomegalovirus sensing for IFN-alpha release and initiation of immune responses in vivo

scientific article published on 01 November 2005

MyD88-mediated signaling prevents development of adenocarcinomas of the colon: role of interleukin 18

scientific article

Mycobacterium tuberculosis triggers host type I IFN signaling to regulate IL-1β production in human macrophages

scientific article

NK cell-derived interferon-γ orchestrates cellular dynamics and the differentiation of monocytes into dendritic cells at the site of infection

scientific article

Non-classical Immunity Controls Microbiota Impact on Skin Immunity and Tissue Repair

article

OSCAR is an FcRgamma-associated receptor that is expressed by myeloid cells and is involved in antigen presentation and activation of human dendritic cells

scientific article

On-going Mechanical Damage from Mastication Drives Homeostatic Th17 Cell Responses at the Oral Barrier

scientific article published on 6 January 2017

Oncogene-driven intrinsic inflammation induces leukocyte production of tumor necrosis factor that critically contributes to mammary carcinogenesis

scientific article published on 5 October 2010

Origin and filiation of human plasmacytoid dendritic cells

scientific article

Persistent decreases in blood plasmacytoid dendritic cell number and function despite effective highly active antiretroviral therapy and increased blood myeloid dendritic cells in HIV-infected individuals

scientific article published on 01 May 2002

Perspectives in melanoma: meeting report from the "Melanoma Bridge" (December 5th-7th, 2019, Naples, Italy)

scientific article published on 07 September 2020

Plasmacytoid dendritic cells in immunity

scientific article

Plasmacytoid dendritic cells mediate oral tolerance

scientific article published on September 2008

Plasmacytoid dendritic cells: one-trick ponies or workhorses of the immune system?

scientific article

Potent suppression of IL-12 production from monocytes and dendritic cells during endotoxin tolerance

article

Potent suppression of IL-12 production from monocytes and dendritic cells during endotoxin tolerance

scientific article published on 01 October 1998

Production of type I interferons: plasmacytoid dendritic cells and beyond

scientific article

Proteus mirabilis: The Enemy Within

scientific article published on April 2015

Reciprocal activating interaction between natural killer cells and dendritic cells

scientific article published on February 2002

Recognition of double-stranded RNA by human toll-like receptor 3 and downstream receptor signaling requires multimerization and an acidic pH.

scientific article published on 6 September 2005

Recommendations from the iSBTc-SITC/FDA/NCI Workshop on Immunotherapy Biomarkers

scientific article

Redirecting in vivo elicited tumor infiltrating macrophages and dendritic cells towards tumor rejection.

scientific article

Regulation of interleukin-12/interleukin-23 production and the T-helper 17 response in humans

scientific article published on December 2008

Reinforcing suppression using regulators: a new link between STAT3, IL-23, and Tregs in tumor immunosuppression

scientific article published on 01 February 2009

Requirements for the differentiation of innate T-bethigh memory-phenotype CD4+ T lymphocytes under steady state

scientific article published on 06 July 2020

Reversal of tumor-induced dendritic cell paralysis by CpG immunostimulatory oligonucleotide and anti-interleukin 10 receptor antibody

scientific article

Systematic evaluation of immune regulation and modulation

scientific article published on 21 March 2017

T-Cell Deletion of MyD88 Connects IL17 and IκBζ to RAS Oncogenesis

scientific article published on 04 June 2019

TAP-1 indirectly regulates CD4+ T cell priming in Toxoplasma gondii infection by controlling NK cell IFN-gamma production

scientific article

TLR3 and Rig-like receptor on myeloid dendritic cells and Rig-like receptor on human NK cells are both mandatory for production of IFN-gamma in response to double-stranded RNA

scientific article published on 16 July 2010

The Antimicrobial Peptide CRAMP Is Essential for Colon Homeostasis by Maintaining Microbiota Balance.

scientific article published on 12 February 2018

The Plasticity of Dendritic Cells Populations in Promoting Th-cell Responses

article

The Proinflammatory Myeloid Cell Receptor TREM-1 Controls Kupffer Cell Activation and Development of Hepatocellular Carcinoma ⬇️

scientific article published on June 19, 2012

The cancer microbiome

scientific article published on 11 June 2019

The development of murine plasmacytoid dendritic cell precursors is differentially regulated by FLT3-ligand and granulocyte/macrophage colony-stimulating factor

scientific article

The human papillomavirus type 16 E7 oncoprotein induces a transcriptional repressor complex on the Toll-like receptor 9 promoter

scientific article published on 10 June 2013

The immune score as a new possible approach for the classification of cancer

scientific article published on 3 January 2012

The inducible CXCR3 ligands control plasmacytoid dendritic cell responsiveness to the constitutive chemokine stromal cell-derived factor 1 (SDF-1)/CXCL12

scientific article

The innate immune receptor TREM-1 promotes liver injury and fibrosis

scientific article published on 02 October 2018

The interleukin-12 and interleukin-12 receptor system in normal and transformed human B lymphocytes

scientific article (publication date: April 2002)

The pivotal role of IKKα in the development of spontaneous lung squamous cell carcinomas.

scientific article published on April 2013

The price of immunity ⬇️

scientific article published on September 18, 2012

The reciprocal interaction of NK cells with plasmacytoid or myeloid dendritic cells profoundly affects innate resistance functions

scientific article published in January 2005

Toll-like receptor signaling stimulates cell cycle entry and progression in fibroblasts

scientific article

Transkingdom interactions between Lactobacilli and hepatic mitochondria attenuate western diet-induced diabetes

scientific article published on 04 January 2021

Tumor-specific CD8+ T cells expressing interleukin-12 eradicate established cancers in lymphodepleted hosts

scientific article

Tumour escape from immune surveillance through dendritic cell inactivation

scientific article

Type I interferon dependence of plasmacytoid dendritic cell activation and migration.

scientific article

Type I interferons and IL-12: convergence and cross-regulation among mediators of cellular immunity

Type I interferons and IL-12: convergence and cross-regulation among mediators of cellular immunity

scientific article published on 01 July 2001

Virus overrides the propensity of human CD40L-activated plasmacytoid dendritic cells to produce Th2 mediators through synergistic induction of IFN-{gamma} and Th1 chemokine production

scientific article

Wild Mouse Gut Microbiota Promotes Host Fitness and Improves Disease Resistance.

scientific article published on 17 October 2017

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