List of works by Birgitta Ruth Knudsen

A new DNA sensor system for specific and quantitative detection of mycobacteria

scientific article published on 01 January 2019

Advantages of an optical nanosensor system for the mechanistic analysis of a novel topoisomerase I targeting drug: a case study

scientific article

Characterization of Camptothecin-induced Genomic Changes in the Camptothecin-resistant T-ALL-derived Cell Line CPT-K5.

scientific article published in March 2018

Comparative simulative analysis of single and double stranded truncated octahedral DNA nanocages

scholarly article in RSC Advances, vol. 6 no. 42, 2016

Correlation between topoisomerase I and tyrosyl-DNA phosphodiesterase 1 activities in non-small cell lung cancer tissue

scientific article published on 16 May 2015

DNA hairpins promote temperature controlled cargo encapsulation in a truncated octahedral nanocage structure family

scientific article published on 24 June 2016

DNA-based sensor for real-time measurement of the enzymatic activity of human topoisomerase I

scientific article

Deciphering the structural properties that confer stability to a DNA nanocage.

scientific article

Decreased camptothecin sensitivity of the stem-cell-like fraction of Caco2 cells correlates with an altered phosphorylation pattern of topoisomerase I

scientific article (publication date: 2014)

Detection of the Malaria causing Plasmodium Parasite in Saliva from Infected Patients using Topoisomerase I Activity as a Biomarker.

scientific article published on 7 March 2018

Droplet microfluidics platform for highly sensitive and quantitative detection of malaria-causing Plasmodium parasites based on enzyme activity measurement

scientific article

Enzymatic activity in single cells

scientific article published on 25 July 2019

Imbibition of Femtoliter-Scale DNA-Rich Aqueous Droplets into Porous Nylon Substrates by Molecular Printing

scientific article published on 17 December 2019

Inhibition of Flp recombinase by the topoisomerase I-targeting drugs, camptothecin and NSC-314622.

scientific article

Interlinked DNA nano-circles for measuring topoisomerase II activity at the level of single decatenation events

scientific article

Microfluidics-Enabled Enzyme Activity Measurement in Single Cells

scientific article published in January 2015

Microfluidics-mediated isothermal detection of enzyme activity at the single molecule level

scientific article published on January 2011

Molecular and functional assessment of multicellular cancer spheroids produced in double emulsions enabled by efficient airway resistance based selective surface treatment

Molecular characterization of irinotecan (SN-38) resistant human breast cancer cell lines

scientific article published on 22 January 2016

NanoCluster Beacons as reporter probes in rolling circle enhanced enzyme activity detection

scientific article

Novel DNA sensor system for highly sensitive and quantitative retrovirus detection using virus encoded integrase as a biomarker

scientific article

Novel phosphine sulphide gold(i) complexes: topoisomerase I inhibitors and antiproliferative agents

scientific article published on 28 May 2020

On-slide detection of enzymatic activities in selected single cells.

scientific article published on 5 September 2017

Optimized Detection of Plasmodium falciparum Topoisomerase I Enzyme Activity in a Complex Biological Sample by the Use of Molecular Beacons

scientific article published on 15 November 2016

Peptide Inhibition of Topoisomerase IB from Plasmodium falciparum

scientific article

Quantum dot based DNA nanosensors for amplification-free detection of human topoisomerase I

scholarly article in RSC Advances, vol. 4 no. 5, 2014

Real-Time Label-Free Direct Electronic Monitoring of Topoisomerase Enzyme Binding Kinetics on Graphene.

scientific article published on 7 October 2015

Real-time detection of TDP1 activity using a fluorophore-quencher coupled DNA-biosensor

scientific article published on 25 April 2013

Real-time investigation of human topoisomerase I reaction kinetics using an optical sensor: a fast method for drug screening and determination of active enzyme concentrations

scientific article published on June 2015

Refined Method for Droplet Microfluidics-Enabled Detection of Plasmodium falciparum Encoded Topoisomerase I in Blood from Malaria Patients

scientific article published on 5 October 2015

Replacement of the human topoisomerase linker domain with the plasmodial counterpart renders the enzyme camptothecin resistant

scientific article (publication date: 2013)

Rolling circle amplification-based detection of human topoisomerase I activity on magnetic beads

scientific article

Simulative Analysis of a Truncated Octahedral DNA Nanocage Family Indicates the Single-Stranded Thymidine Linkers as the Major Player for the Conformational Variability

Single-molecule detection of human topoisomerase I cleavage-ligation activity.

scientific article published in January 2009

Specific detection of the cleavage activity of mycobacterial enzymes using a quantum dot based DNA nanosensor.

scientific article published on 30 November 2015

Specific detection of topoisomerase I from the malaria causing P. falciparum parasite using isothermal rolling circle amplification

scientific article

Synthesis and biological evaluation of indeno[1,5]naphthyridines as topoisomerase I (TopI) inhibitors with antiproliferative activity.

scientific article published on 14 March 2016

Synthesis of fluorosurfactants for emulsion-based biological applications.

scientific article

Synthesis of novel hybrid quinolino[4,3-b][1,5]naphthyridines and quinolino[4,3-b][1,5]naphthyridin-6(5H)-one derivatives and biological evaluation as topoisomerase I inhibitors and antiproliferatives

scientific article published on 03 April 2020

Temperature-Controlled Encapsulation and Release of an Active Enzyme in the Cavity of a Self-Assembled DNA Nanocage

scientific article published on 01 November 2013

The Effects of Dithiothreitol on DNA.

scientific article published on 24 May 2017

Topoisomerase I activity and sensitivity to camptothecin in breast cancer-derived cells: a comparative study

scientific article published on 29 November 2019

Topoisomerase I as a biomarker: detection of activity at the single molecule level.

scientific article published on January 2013

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