List of works - Simonetta Astigiano

A highly invasive subpopulation of MDA-MB-231 breast cancer cells shows accelerated growth, differential chemoresistance, features of apocrine tumors and reduced tumorigenicity in vivo

scientific article published on 10 September 2016

Adaptive phenotype drives resistance to androgen deprivation therapy in prostate cancer.

scientific article

Arginase 2 is expressed by human lung cancer, but it neither induces immune suppression, nor affects disease progression

scientific article

BMP-mediated functional cooperation between Dlx5;Dlx6 and Msx1;Msx2 during mammalian limb development

scientific article

Combined immunotherapy with anti-PDL-1/PD-1 and anti-CD4 antibodies cures syngeneic disseminated neuroblastoma.

scientific article published on 25 October 2017

Comparative analysis of molecular signatures suggests the use of gabapentin for the management of endometriosis-associated pain

scientific article published on 10 April 2018

Curcumin inhibits prostate cancer metastasis in vivo by targeting the inflammatory cytokines CXCL1 and -2.

scientific article

Depletion of cartilage collagen fibrils in mice carrying a dominant negative Col2a1 transgene affects chondrocyte differentiation.

scientific article published on 13 August 2003

Distinct populations of tumor-initiating cells derived from a tumor generated by rat mammary cancer stem cells.

scholarly article

Diverse human aldolase C gene promoter regions are required to direct specific LacZ expression in the hippocampus and Purkinje cells of transgenic mice.

scientific article

Eosinophil granulocytes account for indoleamine 2,3-dioxygenase-mediated immune escape in human non-small cell lung cancer.

scientific article

Exocytosis of azurophil and arginase 1-containing granules by activated polymorphonuclear neutrophils is required to inhibit T lymphocyte proliferation.

scientific article

FMS*Calciumfluor specifically increases mRNA levels and induces signaling via MAPK 42,44 and not FAK in differentiating rat osteoblasts.

scientific article published in August 2005

In vivo generation of decidual natural killer cells from resident hematopoietic progenitors.

scientific article published on 31 October 2013

Inhibition of ductal morphogenesis in the mammary gland of WAP -fgf4 transgenic mice.

scientific article published on 18 April 2003

Modulation of alpha 6/beta 1 integrin expression during differentiation of F9 murine embryonal carcinoma cells to parietal endoderm.

scientific article published on May 1997

Multifocal Signal Modulation Therapy by Celecoxib: A Strategy for Managing Castration-Resistant Prostate Cancer

scientific article published on 03 December 2019

Mutually exclusive expression of DLX2 and DLX5/6 is associated with the metastatic potential of the human breast cancer cell line MDA-MB-231

scientific article

Procollagen I COOH-terminal fragment induces VEGF-A and CXCR4 expression in breast carcinoma cells.

scientific article

Role of the alpha3beta1 and alpha6beta4 integrins in tumor invasion

scientific article

Spatio-temporal dynamics of gene expression of the Edn1-Dlx5/6 pathway during development of the lower jaw

scientific article (publication date: 23 March 2010)

Stage-dependent induction of prenatal tumors in mice by the Kirsten and Moloney strains of murine sarcoma viruses.

scientific article published in December 1985

Systemic alkalinisation delays prostate cancer cell progression in TRAMP mice.

scientific article published on December 2017

TAp73 is downregulated in oocytes from women of advanced reproductive age.

scientific article published on October 2011

The carboxyl terminal trimer of procollagen I induces pro-metastatic changes and vascularization in breast cancer cells xenografts

scientific article

The properties of a mammary gland cancer stem cell

scholarly article

Three-dimensional cultures of normal human osteoblasts: proliferation and differentiation potential in vitro and upon ectopic implantation in nude mice.

scientific article published in May 2002

Transgenic mice overexpressing arginase 1 in monocytic cell lineage are affected by lympho-myeloproliferative disorders and disseminated intravascular coagulation.

scientific article published on 10 September 2015

Treatment of newborn G6pc(-/-) mice with bone marrow-derived myelomonocytes induces liver repair.

scientific article published on 13 April 2011

miR181b is induced by the chemopreventive polyphenol curcumin and inhibits breast cancer metastasis via down-regulation of the inflammatory cytokines CXCL1 and -2.

scientific article published on 16 January 2014

List of works by Simonetta Astigiano

A highly invasive subpopulation of MDA-MB-231 breast cancer cells shows accelerated growth, differential chemoresistance, features of apocrine tumors and reduced tumorigenicity in vivo

Adaptive phenotype drives resistance to androgen deprivation therapy in prostate cancer.

Arginase 2 is expressed by human lung cancer, but it neither induces immune suppression, nor affects disease progression

BMP-mediated functional cooperation between Dlx5;Dlx6 and Msx1;Msx2 during mammalian limb development

Combined immunotherapy with anti-PDL-1/PD-1 and anti-CD4 antibodies cures syngeneic disseminated neuroblastoma.

Comparative analysis of molecular signatures suggests the use of gabapentin for the management of endometriosis-associated pain

Curcumin inhibits prostate cancer metastasis in vivo by targeting the inflammatory cytokines CXCL1 and -2.

Depletion of cartilage collagen fibrils in mice carrying a dominant negative Col2a1 transgene affects chondrocyte differentiation.

Distinct populations of tumor-initiating cells derived from a tumor generated by rat mammary cancer stem cells.

Diverse human aldolase C gene promoter regions are required to direct specific LacZ expression in the hippocampus and Purkinje cells of transgenic mice.

Eosinophil granulocytes account for indoleamine 2,3-dioxygenase-mediated immune escape in human non-small cell lung cancer.

Exocytosis of azurophil and arginase 1-containing granules by activated polymorphonuclear neutrophils is required to inhibit T lymphocyte proliferation.

FMS*Calciumfluor specifically increases mRNA levels and induces signaling via MAPK 42,44 and not FAK in differentiating rat osteoblasts.

In vivo generation of decidual natural killer cells from resident hematopoietic progenitors.

Inhibition of ductal morphogenesis in the mammary gland of WAP -fgf4 transgenic mice.

Modulation of alpha 6/beta 1 integrin expression during differentiation of F9 murine embryonal carcinoma cells to parietal endoderm.

Multifocal Signal Modulation Therapy by Celecoxib: A Strategy for Managing Castration-Resistant Prostate Cancer

Mutually exclusive expression of DLX2 and DLX5/6 is associated with the metastatic potential of the human breast cancer cell line MDA-MB-231

Procollagen I COOH-terminal fragment induces VEGF-A and CXCR4 expression in breast carcinoma cells.

Role of the alpha3beta1 and alpha6beta4 integrins in tumor invasion

Spatio-temporal dynamics of gene expression of the Edn1-Dlx5/6 pathway during development of the lower jaw

Stage-dependent induction of prenatal tumors in mice by the Kirsten and Moloney strains of murine sarcoma viruses.

Systemic alkalinisation delays prostate cancer cell progression in TRAMP mice.

TAp73 is downregulated in oocytes from women of advanced reproductive age.

The carboxyl terminal trimer of procollagen I induces pro-metastatic changes and vascularization in breast cancer cells xenografts

The properties of a mammary gland cancer stem cell

Three-dimensional cultures of normal human osteoblasts: proliferation and differentiation potential in vitro and upon ectopic implantation in nude mice.

Transgenic mice overexpressing arginase 1 in monocytic cell lineage are affected by lympho-myeloproliferative disorders and disseminated intravascular coagulation.

Treatment of newborn G6pc(-/-) mice with bone marrow-derived myelomonocytes induces liver repair.

miR181b is induced by the chemopreventive polyphenol curcumin and inhibits breast cancer metastasis via down-regulation of the inflammatory cytokines CXCL1 and -2.