List of works by Olivier Chinot

A Phase II randomized study of galunisertib monotherapy or galunisertib plus lomustine compared with lomustine monotherapy in patients with recurrent glioblastoma

scientific article published on 21 February 2016

A case of cerebello-thalamo-cortical diaschisis.

scientific article published in October 2008

A multicenter prospective observational study of the conformity of temozolomide prescriptions in France.

scientific article published on 15 March 2012

AI-29ANGIOGENIC SWITCH FROM VEGFR2/HIF1α IN NEWLY DIAGNOSED GLIOBLASTOMA (GB) TO CXCR4-SDF1 PATHWAY IN RECURRENT PAIRED TUMOR AFTER RADIOTHERAPY (RT)-TEMOZOLOMIDE (TMZ).

scientific article published in November 2014

AP-HM tumour tissue bank: molecular signature of gliomas

scientific article

ASSOCIATION OF MATRIX METALLOPROTEINASE 2 (MMP2) BASELINE PLASMA LEVEL WITH RESPONSE AND SURVIVAL AND CHANGE OVERTIME IN PATIENTS TREATED WITH BEVACIZUMAB FOR RECURRENT HIGH GRADE GLIOMA.

scientific article published in July 2014

AT-17RE-ANALYSIS OF PFS/RESPONSE USING ORIGINAL MACDONALD CRITERIA AND RESPONSE EVALUATION CRITERIA IN SOLID TUMORS IN THE PHASE III AVAGLIO STUDY OF BEVACIZUMAB PLUS RADIOTHERAPY AND TEMOZOLOMIDE IN NEWLY DIAGNOSED GLIOBLASTOMA

AT-18SURVIVAL ANALYSIS OF PATIENTS WITH A PFS EVENT WHO DID NOT RECEIVE POST-PROGRESSION THERAPY IN AVAGLIO (BEVACIZUMAB [BEV] PLUS RADIOTHERAPY [RT] AND TEMOZOLOMIDE [TMZ] FOR NEWLY DIAGNOSED GLIOBLASTOMA [GBM])

ATNT-10DOES VALPROIC ACID IMPROVE SURVIVAL IN GLIOBLASTOMA? A META-ANALYSIS OF RANDOMIZED TRIALS IN NEWLY DIAGNOSED GLIOBLASTOMA.

scientific article

AVAglio: Phase 3 trial of bevacizumab plus temozolomide and radiotherapy in newly diagnosed glioblastoma multiforme.

scientific article

Absence of IDH mutation identifies a novel radiologic and molecular subtype of WHO grade II gliomas with dismal prognosis

scientific article

Adrenomedullin blockade induces regression of tumor neovessels through interference with vascular endothelial-cadherin signalling

scientific article published on April 2015

Adult intracranial WHO grade II ependymomas: long-term outcome and prognostic factor analysis in a series of 114 patients

scientific article

Adult intramedullary gliomas

scientific article published on 18 May 2017

Allelic loss of 9p21.3 is a prognostic factor in 1p/19q codeleted anaplastic gliomas

scientific article

An ANOCEF genomic and transcriptomic microarray study of the response to irinotecan and bevacizumab in recurrent glioblastomas

scientific article published on 2 April 2014

An ANOCEF genomic and transcriptomic microarray study of the response to radiotherapy or to alkylating first-line chemotherapy in glioblastoma patients

scientific article

Assessing the quality of life among caregivers of patients with gliomas

scientific article

BI-22CORRELATION OF MOLECULAR SUBTYPES WITH OVERALL SURVIVAL (OS) IN AVAGLIO, A RANDOMIZED, PLACEBO-CONTROLLED STUDY OF BEVACIZUMAB (BEV) PLUS RADIOTHERAPY (RT) AND TEMOZOLOMIDE (TMZ) FOR NEWLY DIAGNOSED GLIOBLASTOMA (GBM)

BRAF mutation and anaplasia may be predictive factors of progression-free survival in adult pleomorphic xanthoastrocytoma.

scientific article

Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma

scientific article published in February 2014

Bevacizumab, temozolomide, and radiotherapy for newly diagnosed glioblastoma: comprehensive safety results during and after first-line therapy

scientific article

Bing-Neel syndrome: a cerebral Richter syndrome?

scientific article published in March 2014

Biological heterogeneity of ER-positive breast cancers in the post-menopausal population

scientific article

Biological profiles of malignant gliomas

scientific article

Biomarker and Histopathology Evaluation of Patients with Recurrent Glioblastoma Treated with Galunisertib, Lomustine, or the Combination of Galunisertib and Lomustine

scientific article

CN-18RELATIONSHIPS BETWEEN DOSE INTENSITY, TOXICITY, AND OUTCOME IN OLIGODENDROGLIAL TUMORS (OG) TREATED WITH PCV REGIMEN

Cerebral metastases

scientific article

Changes in PlGF and MET-HGF expressions in paired initial and recurrent glioblastoma

scientific article

Chemotherapy alone as initial treatment for primary CNS lymphoma in patients older than 60 years: a multicenter phase II study (26952) of the European Organization for Research and Treatment of Cancer Brain Tumor Group

scientific article published in July 2003

Chemotherapy and targeted treatments in glioblastomas

scientific article published on 28 October 2010

Chemotherapy for the treatment of oligodendroglial tumors

scientific article

Cilengitide in glioblastoma: when did it fail?

scientific article

Clinical implications of quantitative real-time RT-PCR analysis of hTERT gene expression in human gliomas

scientific article published on February 2003

Clinical validation of the CE-IVD marked Therascreen MGMT kit in a cohort of glioblastoma patients.

scientific article

Combined treatment by octreotide and everolimus: Octreotide enhances inhibitory effect of everolimus in aggressive meningiomas.

scientific article published on 27 May 2015

Comparative assessment of 5 methods (methylation-specific polymerase chain reaction, MethyLight, pyrosequencing, methylation-sensitive high-resolution melting, and immunohistochemistry) to analyze O6-methylguanine-DNA-methyltranferase in a series of

scientific article

Contribution of biology to the therapeutic decision: cancer of the breast in 1995

scientific article published in January 1995

Coping with a newly diagnosed high-grade glioma: patient-caregiver dyad effects on quality of life.

scientific article published on 14 June 2016

Correction: SNP Array Analysis Reveals Novel Genomic Abnormalities Including Copy Neutral Loss of Heterozygosity in Anaplastic Oligodendrogliomas.

scientific article published on 8 May 2013

Correlation between O6-methylguanine-DNA methyltransferase and survival in inoperable newly diagnosed glioblastoma patients treated with neoadjuvant temozolomide

scientific article

Deletions of chromosomes 1p and 19q are detectable on frozen smears of gliomas by FISH: usefulness for stereotactic biopsies

scientific article published on 01 June 2004

Differential scanning calorimetry of plasma in glioblastoma: toward a new prognostic / monitoring tool.

scientific article published on 25 January 2018

Does Valproic Acid or Levetiracetam Improve Survival in Glioblastoma? A Pooled Analysis of Prospective Clinical Trials in Newly Diagnosed Glioblastoma

scientific article published on 19 January 2016

Domains of quality of life freely expressed by cancer patients and their caregivers: contribution of the SEIQoL.

scientific article

Dyadic effects of coping strategies, time perspectives, and personality on the quality of life of cancer patients and their caregivers

scientific article published on 5 September 2017

EANO guideline for the diagnosis and treatment of anaplastic gliomas and glioblastoma.

scientific article published in August 2014

ET-12PHASE II STUDY OF ONARTUZUMAB PLUS BEVACIZUMAB VERSUS PLACEBO PLUS BEVACIZUMAB IN PATIENTS WITH RECURRENT GLIOBLASTOMA.

scientific article published in November 2014

End-binding 1 protein overexpression correlates with glioblastoma progression and sensitizes to Vinca-alkaloids in vitro and in vivo

scientific article

Epidermal growth factor receptor in glioblastomas: correlation between gene copy number and protein expression

scientific article published on 29 March 2010

European Association for Neuro-Oncology (EANO) guideline on the diagnosis and treatment of adult astrocytic and oligodendroglial gliomas.

scientific article published on 5 May 2017

Evaluation of fractionated radiotherapy and gamma knife radiosurgery in cavernous sinus meningiomas: treatment strategy

scientific article published on 01 November 2005

Everolimus and Octreotide for Patients with Recurrent Meningioma: Results from the Phase II CEVOREM Trial

scientific article published on 22 January 2020

Evidence-based management of adult patients with diffuse glioma - Authors' reply

scientific article

Expression-based intrinsic glioma subtypes are prognostic in low-grade gliomas of the EORTC22033-26033 clinical trial.

scientific article

Health-Related Quality of Life in a Randomized Phase III Study of Bevacizumab, Temozolomide, and Radiotherapy in Newly Diagnosed Glioblastoma

scientific article published on 26 May 2015

Health-related quality of life in patients with high-risk low-grade glioma (EORTC 22033-26033): a randomised, open-label, phase 3 intergroup study

scientific article published on 26 September 2016

High-grade glioma in elderly patients: can the oncogeriatrician help?

scientific article published on 06 December 2013

Histological and MR correlations in Gliomatosis cerebri

scientific article published in September 2002

Hydroxyurea treatment for unresectable meningioma

scientific article published in September 2004

IDH mutation is paradoxically associated with higher 18F-FDOPA PET uptake in diffuse grade II and grade III gliomas

scientific article published on 14 March 2017

Identification of secondary structure in the 5'-untranslated region of the human adrenomedullin mRNA with implications for the regulation of mRNA translation

scientific article published on 22 May 2006

Independent prognostic value of pre-treatment 18-FDG-PET in high-grade gliomas

scientific article

Initial chemotherapy in gliomatosis cerebri.

scientific article

Interim results from the CATNON trial (EORTC study 26053-22054) of treatment with concurrent and adjuvant temozolomide for 1p/19q non-co-deleted anaplastic glioma: a phase 3, randomised, open-label intergroup study

scientific article

Intracerebral administration of CpG oligonucleotide for patients with recurrent glioblastoma: a phase II study

scientific article

Intracranial ependymomas in adult patients. Diagnosis and histological prognostic factors

scientific article

Limited impact of prognostic factors in patients with recurrent glioblastoma multiforme treated with a bevacizumab-based regimen.

scientific article published on 12 June 2013

Links between private habits, psychological stress and brain cancer: a case-control pilot study in France.

scientific article

Long-term tumor control and functional outcome in patients with cavernous sinus meningiomas treated by radiotherapy with or without previous surgery: is there an alternative to aggressive tumor removal?

scientific article

MALDI imaging and in-source decay for top-down characterization of glioblastoma

scientific article

MMP2 and MMP9 as candidate biomarkers to monitor bevacizumab therapy in high-grade glioma

scientific article published on August 2015

MMP2 and MMP9 serum levels are associated with favorable outcome in patients with inflammatory breast cancer treated with bevacizumab-based neoadjuvant chemotherapy in the BEVERLY-2 study.

scientific article

Methotrexate and temozolomide versus methotrexate, procarbazine, vincristine, and cytarabine for primary CNS lymphoma in an elderly population: an intergroup ANOCEF-GOELAMS randomised phase 2 trial.

scientific article published on 3 June 2015

Mitotic index, microvascular proliferation, and necrosis define 3 groups of 1p/19q codeleted anaplastic oligodendrogliomas associated with different genomic alterations

scientific article

Multimodal MR imaging (diffusion, perfusion, and spectroscopy): is it possible to distinguish oligodendroglial tumor grade and 1p/19q codeletion in the pretherapeutic diagnosis?

scientific article published on 6 December 2012

Neuro-oncological patients admitted in intensive-care unit: predictive factors and functional outcome

scientific article published on 25 November 2015

New place of the chemotherapy in gliomas

scientific article published in April 2005

OS6.6 CEVOREM Trial: Combination of EVerolimus and Octreotide in REsistant MeningiomasPresentation and Preliminary results.

scientific article published on 21 September 2016

OS7.6 Management patterns and outcome of patients with primary CNS lymphoma (PCNSL) in France during 2011–2016. A LOC network study.

scientific article published on 21 September 2016

Octreotide therapy in meningiomas: in vitro study, clinical correlation, and literature review

scientific article published on 16 December 2016

Oncological patterns of care and outcome for 952 patients with newly diagnosed glioblastoma in 2004.

scientific article

Oncological patterns of care and outcomes for 265 elderly patients with newly diagnosed glioblastoma in France

scientific article

P04.07EXPRESSION PROFILE OF ANGIOGENIC FACTORS IN PAIRED INITIAL AND RECURRENT GLIOBLASTOMA.

scientific article published in September 2014

P04.08PLASMA LEVELS AND TUMOR TISSUE RNA OF MMP2 AND MMP9 EXHIBIT SIMILAR DISTRIBUTION IN NEWLY DIAGNOSED AND RECURRENT GLIOBLASTOMA (GB).

scientific article published in September 2014

P08.07LEPTOMENINGEAL GLIOMATOSIS: A SINGLE INSTITUTION RETROSPECTIVE STUDY OF 31 PATIENTS.

scientific article published in September 2014

P08.63 Dose optimization of MK-8628 (OTX015), a small molecule inhibitor of bromodomain and extra-terminal (BET) proteins, in patients with recurrent glioblastoma.

scientific article published on 21 September 2016

P11.11 Aggressive Meningiomas: In vitro study of the combination pasireotide-everolimus vs. octreotide everolimus.

scientific article published on 21 September 2016

P17.20PATTERNS OF CARE AND OUTCOME FOR PATIENTS WITH RECURRENT GLIOBLASTOMA.

scientific article published in September 2014

P20.01 MEVITEM: A European, randomized, open-label Phase I/II study of vismodegib in combination with temozolomide versus temozolomide alone in adult patients with recurrent or refractory medulloblastoma presenting an activation of the Sonic Hedgeho

scientific article

Patients With Proneural Glioblastoma May Derive Overall Survival Benefit From the Addition of Bevacizumab to First-Line Radiotherapy and Temozolomide: Retrospective Analysis of the AVAglio Trial

scientific article published on 29 June 2015

Patterns of response and relapse in primary CNS lymphomas after first-line chemotherapy: imaging analysis of the ANOCEF-GOELAMS prospective randomized trial.

scientific article

Phase 1 dose-escalation study of the antiplacental growth factor monoclonal antibody RO5323441 combined with bevacizumab in patients with recurrent glioblastoma.

scientific article published on 9 February 2015

Phase II study of first-line chemotherapy with temozolomide in recurrent oligodendroglial tumors: the European Organization for Research and Treatment of Cancer Brain Tumor Group Study 26971.

scientific article

Phase II study of temozolomide without radiotherapy in newly diagnosed glioblastoma multiforme in an elderly populations

scientific article

Pineal region tumors: the role of stereotactic radiosurgery

scientific article published on 01 January 1996

Plasma YKL-40 as a biomarker for bevacizumab efficacy in patients with newly diagnosed glioblastoma in the phase 3 randomized AVAglio trial

scientific article published on 4 December 2017

Polysialic acid neural cell adhesion molecule (PSA-NCAM) is an adverse prognosis factor in glioblastoma, and regulates olig2 expression in glioma cell lines

scientific article

Post-chemoradiation volumetric response predicts survival in newly diagnosed glioblastoma treated with radiation, temozolomide, and bevacizumab or placebo

scientific article published on 01 October 2018

Predictive biomarkers investigated in glioblastoma.

scientific article published on 05 August 2014

Prescription guidebook for temozolomide usage in brain tumors

scientific article

Primary CNS lymphoma at first relapse/progression: characteristics, management, and outcome of 256 patients from the French LOC network.

scientific article published on 6 March 2016

Primary CNS lymphoma in patients younger than 60: can whole-brain radiotherapy be deferred?

scientific article published on 19 December 2010

Primary neurolymphomatosis diagnosis and treatment: a retrospective study

scientific article published on 01 May 2014

Prognostic impact of the 2016 WHO classification of diffuse gliomas in the French POLA cohort

scientific article

Prognostic implications of biologic markers in intracranial meningiomas: 120 cases

scientific article published on 28 August 2008

Prognostic significance of Ki67, p53 and epidermal growth factor receptor immunostaining in human glioblastomas.

scientific article published in October 1998

Prognostic value of cytosolic thymidine kinase activity as a marker of proliferation in breast cancer.

scientific article

Prognostic value of cytosolic tyrosine kinase activity in 249 node-positive breast cancer patients.

scientific article

Promoter Methylation Cutoff with Safety Margin for Selecting Glioblastoma Patients into Trials Omitting Temozolomide: A Pooled Analysis of Four Clinical Trials

scientific article published on 04 December 2018

Radiologic progression of glioblastoma under therapy - an exploratory analysis of AVAglio

scientific article published in September 2017

Radiotherapy for glioblastoma in the elderly.

scientific article published in April 2007

Randomized phase II trial of irinotecan and bevacizumab as neo-adjuvant and adjuvant to temozolomide-based chemoradiation compared with temozolomide-chemoradiation for unresectable glioblastoma: final results of the TEMAVIR study from ANOCEF†.

scientific article

Randomized, Double-Blind, Placebo-Controlled, Multicenter Phase II Study of Onartuzumab Plus Bevacizumab Versus Placebo Plus Bevacizumab in Patients With Recurrent Glioblastoma: Efficacy, Safety, and Hepatocyte Growth Factor and O6-Methylguanine-DNA

scientific article

Recent developments in the molecular characterization and treatment of oligodendroglial tumors

scientific article published in April 2003

Recent trends in epidemiology of brain metastases: an overview.

scientific article

Recurrence of glioblastoma after radio-chemotherapy is associated with an angiogenic switch to the CXCL12-CXCR4 pathway

scientific article published on May 2015

Recurrent extraneural sonic hedgehog medulloblastoma exhibiting sustained response to vismodegib and temozolomide monotherapies and inter-metastatic molecular heterogeneity at progression.

scientific article

Recurrent mutations of MYD88 and TBL1XR1 in primary central nervous system lymphomas

scientific article published on 26 July 2012

Reirradiation and concomitant metronomic temozolomide: an efficient combination for local control in medulloblastoma disease?

scientific article

Relationship between magnetic resonance imaging characteristics and plasmatic levels of MMP2 and MMP9 in patients with recurrent high-grade gliomas treated by Bevacizumab and Irinotecan

scientific article published on 06 March 2017

Relationships Between Dose Intensity, Toxicity, and Outcome in Patients with Oligodendroglial Tumors Treated with the PCV Regimen

scientific article

Response assessment criteria for glioblastoma: practical adaptation and implementation in clinical trials of antiangiogenic therapy.

scientific article

SM-08NEURO-ONCOLOGICAL PATIENTS ADMITTED IN INTENSIVE-CARE UNIT (ICU): PATIENT'S CHARACTERISTICS, PREDICTIVE FACTORS OF DEATH IN ICU AND FUNCTIONAL OUTCOME.

scientific article published in November 2014

SNP array analysis reveals novel genomic abnormalities including copy neutral loss of heterozygosity in anaplastic oligodendrogliomas

scientific article

Safety and efficacy of temozolomide in patients with recurrent anaplastic oligodendrogliomas after standard radiotherapy and chemotherapy.

scientific article

Second-line chemotherapy with temozolomide in recurrent oligodendroglioma after PCV (procarbazine, lomustine and vincristine) chemotherapy: EORTC Brain Tumor Group phase II study 26972.

scientific article

Short-Course Radiation plus Temozolomide in Elderly Patients with Glioblastoma

scientific article published on March 2017

Should radiotherapy be standard therapy for brain tumors in the elderly? Cons.

scientific article published on December 2003

Summary version of the Standards, Options and Recommendations for the management of adult patients with intracranial glioma (2002).

scientific article published on August 2003

Technical evaluation of thymidine kinase assay in cytosols from breast cancers. EORTC Receptor Study Group Report.

scientific article

Temozolomide Plus Bevacizumab in Elderly Patients with Newly Diagnosed Glioblastoma and Poor Performance Status: An ANOCEF Phase II Trial (ATAG).

scientific article

Temozolomide chemotherapy versus radiotherapy in high-risk low-grade glioma (EORTC 22033-26033): a randomised, open-label, phase 3 intergroup study

scientific article published on 26 September 2016

Temozolomide in combination with BCNU before and after radiotherapy in patients with inoperable newly diagnosed glioblastoma multiforme

scientific article

Temozolomide in elderly patients with newly diagnosed glioblastoma and poor performance status: an ANOCEF phase II trial

scientific article

The CareGiver Oncology Quality of Life questionnaire (CarGOQoL): development and validation of an instrument to measure the quality of life of the caregivers of patients with cancer

scientific article published on 25 October 2011

The DNA methylome of DDR genes and benefit from RT or TMZ in IDH mutant low-grade glioma treated in EORTC 22033.

scientific article

The role of Gamma Knife radiosurgery in the treatment of pineal parenchymal tumours

scientific article published on 19 September 2005

Treatment of primary central nervous system lymphoma in the elderly.

scientific article published on December 2003

Tubulin isoforms identified in the brain by MALDI in-source decay

scientific article

Understanding the quality of life (QOL) issues in survivors of cancer: towards the development of an EORTC QOL cancer survivorship questionnaire.

scientific article published on 4 June 2018

[Biological data on the concept of risk. Is the aimed target the right one?]

scientific article

[Burkitt lymphoma of the cavernous sinus. Apropos of a case]

scientific article published on 01 December 2001

[Intracranial ependymomas in adult patients. Retrospective analysis of 121 cases from the multicentric French study]

scientific article published in June 2007

[Magnetic resonance spectroscopy in gliomas].

scientific article

[Neuropathology of lymphoma]

scientific article published on 01 April 2008

[Participation in the national experiment of cancer diagnosis disclosure in neuro-oncology: implications and the perception of the health care team]

scientific article published on 01 April 2005

[Place of chemotherapy and radiotherapy in the management of oligodendrogliomas]

scientific article published in September 2005

[Role of adrenomedullin in glioblastomas growth].

scientific article

[Standards, Options and Recommendations 2002 for the management of adult patients with intracranial gliomas (summary report)].

scientific article published in October 2003

[Value of relative cerebral blood volume measurement using perfusion MRI in glioma management]

scientific article published on 24 June 2008

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