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List of works by Ivan Poon

A novel mechanism of generating extracellular vesicles during apoptosis via a beads-on-a-string membrane structure

scientific article

A tumor cell-specific nuclear targeting signal within chicken anemia virus VP3/apoptin.

scientific article published on January 2005

Analysis of extracellular vesicles generated from monocytes under conditions of lytic cell death

scientific article published on 17 May 2019

Apoptin nuclear accumulation is modulated by a CRM1-recognized nuclear export signal that is active in normal but not in tumor cells

scientific article published on August 2005

Apoptotic Cell-Derived Extracellular Vesicles: More Than Just Debris.

scientific article published on 28 June 2018

Apoptotic cell clearance: basic biology and therapeutic potential.

scientific article

Binding of phosphatidic acid by NsD7 mediates the formation of helical defensin-lipid oligomeric assemblies and membrane permeabilization

scientific article published on 19 September 2016

Calmodulin-dependent nuclear import of HMG-box family nuclear factors: importance of the role of SRY in sex reversal.

scientific article

Cell disassembly during apoptosis ⬇️

scholarly article

Combating Human Pathogens and Cancer by Targeting Phosphoinositides and Their Metabolism

scientific article published on 31 October 2019

Correction to: Defining the role of cytoskeletal components in the formation of apoptopodia and apoptotic bodies during apoptosis

scientific article published on 01 December 2019

Crystal structure of ligand-bound NaD1

scholarly article published 16 April 2014

Defining the morphologic features and products of cell disassembly during apoptosis.

scientific article

Defining the role of cytoskeletal components in the formation of apoptopodia and apoptotic bodies during apoptosis

scientific article published on 01 December 2019

Detection and Isolation of Apoptotic Bodies to High Purity

scientific article published on 12 August 2018

Determining the contents and cell origins of apoptotic bodies by flow cytometry

scientific article published on 31 October 2017

Dimerization of Plant Defensin NaD1 Enhances Its Antifungal Activity

scientific article

Disassembly of dying cells in diverse organisms

article

Disassembly of the Dying: Mechanisms and Functions.

scientific article published on 16 September 2016

Divalent metal binding by histidine-rich glycoprotein differentially regulates higher order oligomerisation and proteolytic processing.

scientific article published on 8 December 2016

Editorial: The Immunomodulatory Properties of Extracellular Vesicles From Pathogens, Immune Cells, and Non-immune Cells

scientific article published on 19 December 2018

Endothelial cell apoptosis and the role of endothelial cell-derived extracellular vesicles in the progression of atherosclerosis

scientific article published on 19 December 2018

Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling

scientific article published on 09 August 2019

Functional Regulation of the Plasma Protein Histidine-Rich Glycoprotein by Zn2+ in Settings of Tissue Injury

scientific article

Gasdermin E Does Not Limit Apoptotic Cell Disassembly by Promoting Early Onset of Secondary Necrosis in Jurkat T Cells and THP-1 Monocytes

scientific article published on 04 December 2018

Histidine-rich glycoprotein binds heparanase and regulates its enzymatic activity and cell surface interactions

scientific article

Histidine-rich glycoprotein functions cooperatively with cell surface heparan sulfate on phagocytes to promote necrotic cell uptake.

scientific article published on 23 June 2010

Histidine-rich glycoprotein is a novel plasma pattern recognition molecule that recruits IgG to facilitate necrotic cell clearance via Fc RI on phagocytes

scientific article published on 13 January 2010

Histidine-rich glycoprotein specifically binds to necrotic cells via its amino-terminal domain and facilitates necrotic cell phagocytosis

scientific article published on 17 August 2005

Histidine-rich glycoprotein: the Swiss Army knife of mammalian plasma

scientific article

Human MAIT cell cytolytic effector proteins synergize to overcome carbapenem resistance in Escherichia coli

scientific article published on 08 June 2020

Human β-defensin 3 contains an oncolytic motif that binds PI(4,5)P2 to mediate tumour cell permeabilisation.

scientific article published on 9 December 2015

Identification of a novel mitochondrial uncoupler that does not depolarize the plasma membrane

scientific article

Interaction with PI3-kinase contributes to the cytotoxic activity of apoptin

scientific article

Isolation of cell type-specific apoptotic bodies by fluorescence-activated cell sorting

scientific article published on 06 January 2017

Metabolic vulnerabilities in endometrial cancer

scientific article

Methods for monitoring the progression of cell death, cell disassembly and cell clearance

scientific article published on 01 April 2019

Mice deficient in heparanase exhibit impaired dendritic cell migration and reduced airway inflammation

scientific article published on 14 February 2014

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

scientific article published on 23 November 2018

Molecular mechanisms of late apoptotic/necrotic cell clearance

scientific article

Monitoring the progression of cell death and the disassembly of dying cells by flow cytometry.

scientific article published on 03 March 2016

Monocyte apoptotic bodies are vehicles for influenza A virus propagation

scientific article published on 08 May 2020

Moving beyond size and phosphatidylserine exposure: evidence for a diversity of apoptotic cell-derived extracellular vesicles

scientific article published on 26 April 2019

NK cell heparanase controls tumor invasion and immune surveillance

scientific article

New method for purifying histidine-rich glycoprotein from human plasma redefines its functional properties

scientific article

Nicotiana alata Defensin Chimeras Reveal Differences in the Mechanism of Fungal and Tumor Cell Killing and an Enhanced Antifungal Variant ⬇️

scientific article published on 8 August 2016

Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis

scientific article published on 24 June 2021

Pannexin 1 Channels as an Unexpected New Target of the Anti-Hypertensive Drug Spironolactone

scientific article published on 13 December 2017

Phenotypic screen for oxygen consumption rate identifies an anti-cancer naphthoquinone that induces mitochondrial oxidative stress

scientific article published on 05 November 2019

Phosphoinositide-mediated oligomerization of a defensin induces cell lysis

scientific article

Phosphoinositides: multipurpose cellular lipids with emerging roles in cell death

scientific article published on 11 February 2019

Plexin B2 Is a Regulator of Monocyte Apoptotic Cell Disassembly

scientific article published on 01 November 2019

Prospective evaluation of pretreatment and intratreatment FDG PET-CT SUV stability in primary head and neck cancer

scientific article published on 28 January 2019

ROCK1 but not LIMK1 or PAK2 is a key regulator of apoptotic membrane blebbing and cell disassembly

scientific article published on 01 May 2019

Regulation of histidine-rich glycoprotein (HRG) function via plasmin-mediated proteolytic cleavage

scientific article

Regulation of nuclear transport: central role in development and transformation?

scientific article

Response by Good et al to Letter Regarding Article, "Pannexin-1 Channels as an Unexpected New Target of the Antihypertensive Drug Spironolactone"

Smac mimetics can provoke lytic cell death that is neither apoptotic nor necroptotic

scientific article published on 21 May 2020

Soluble heparan sulfate fragments generated by heparanase trigger the release of pro-inflammatory cytokines through TLR-4.

scientific article

Structural and Functional Insight into Canarypox Virus CNP058 Mediated Regulation of Apoptosis

scientific article published on 20 October 2017

The Tomato Defensin TPP3 Binds Phosphatidylinositol (4,5)-Bisphosphate via a Conserved Dimeric Cationic Grip Conformation To Mediate Cell Lysis.

scientific article published on 23 March 2015

The endoglycosidase heparanase enters the nucleus of T lymphocytes and modulates H3 methylation at actively transcribed genes via the interplay with key chromatin modifying enzymes

scientific article published on May 2012

The induction and consequences of Influenza A virus-induced cell death

scientific article published on 25 September 2018

The lure of the lipids: how defensins exploit membrane phospholipids to induce cytolysis in target cells.

scientific article published on 30 March 2017

The phospholipid code: a key component of dying cell recognition, tumor progression and host-microbe interactions

scientific article published on 09 October 2015

The plant defensin NaD1 induces tumor cell death via a non-apoptotic, membranolytic process.

scientific article published on 23 January 2017

The plant defensin NaD1 introduces membrane disorder through a specific interaction with the lipid, phosphatidylinositol 4,5 bisphosphate ⬇️

scientific article

Tumor cell membrane-targeting cationic antimicrobial peptides: novel insights into mechanisms of action and therapeutic prospects

scientific article published on 2 August 2017

Unexpected link between an antibiotic, pannexin channels and apoptosis

scientific article

X-ray structure of a carpet-like antimicrobial defensin-phospholipid membrane disruption complex.

scientific article

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