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List of works by Marco Malavolta

+647 A/C and +1245 MT1A polymorphisms in the susceptibility of diabetes mellitus and cardiovascular complications

scientific article published on 30 January 2008

1267 HSP70-2 polymorphism as a risk factor for carotid plaque rupture and cerebral ischaemia in old type 2 diabetes-atherosclerotic patients.

scientific article published on 18 April 2005

A Novel Zip2 Gln/Arg/Leu Codon 2 Polymorphism Is Associated with Carotid Artery Disease in Aging

scientific article published on 01 April 2008

A genetic variant near the equine interleukin 6 gene associated with copper:zinc ratio.

scientific article

Accumulation of cells with short telomeres is associated with impaired zinc homeostasis and inflammation in old hypertensive participants

scientific article published on 9 April 2009

Acetylcholinesterase inhibitors in Alzheimer's disease influence Zinc and Copper homeostasis

scientific article published on 05 June 2019

Age and immunity

scientific article

Age-dependent expression of DNMT1 and DNMT3B in PBMCs from a large European population enrolled in the MARK-AGE study

scientific article

Allyl Isothiocyanate Exhibits No Anticancer Activity in MDA-MB-231 Breast Cancer Cells.

scientific article published on 4 January 2018

Analysis of the machinery and intermediates of the 5hmC-mediated DNA demethylation pathway in aging on samples from the MARK-AGE Study

scientific article published on 29 August 2016

Anti-inflammatory Activity of Tocotrienols in Age-related Pathologies: A SASPected Involvement of Cellular Senescence

scientific article published on 20 November 2018

Antioxidant enzyme activities in healthy old subjects: influence of age, gender and zinc status

scientific article published on 01 October 2006

Antioxidants linked with physical, cognitive and psychological frailty: Analysis of candidate biomarkers and markers derived from the MARK-AGE study

scientific article published on 30 April 2018

Assessment of gene-nutrient interactions on inflammatory status of the elderly with the use of a zinc diet score--ZINCAGE study

scientific article published on 15 May 2009

Association among 1267 A/G HSP70-2, -308 G/A TNF-α polymorphisms and pro-inflammatory plasma mediators in old ZincAge population

scientific article

Association of HERV-K and LINE-1 hypomethylation with reduced disease-free survival in melanoma patients

scientific article published on 30 October 2020

Association of MT1A haplotype with cardiovascular disease and antioxidant enzyme defense in elderly Greek population: comparison with an Italian cohort

scientific article published on 4 December 2009

Association of Torquetenovirus Viremia with Physical Frailty and Cognitive Impairment in Three Independent European Cohorts

scientific article published in 2023

BMI, life-style and psychological conditions in a sample of elderly Italian men and women.

scientific article published in August 2010

CD14 C (-260)T polymorphism, atherosclerosis, elderly: Role of cytokines and metallothioneins

scientific article published on 13 November 2006

COVID-19 and Smoking. Is Nicotine the Hidden Link?

scientific article published on 27 April 2020

Cellular Senescence and Inflammatory Burden as Determinants of Mortality in Elderly People Until the Extreme old age

scientific article

Changes in Zn homeostasis during long term culture of primary endothelial cells and effects of Zn on endothelial cell senescence.

scientific article published on 13 September 2017

Characterization of the hsp70 response in lymphoblasts from aged and centenarian subjects and differential effects of in vitro zinc supplementation.

scientific article

Circadian rhythms of body temperature and locomotor activity in aging BALB/c mice: early and late life span predictors.

scientific article published on 28 January 2016

Comparison of intracellular zinc signals in nonadherent lymphocytes from young-adult and elderly donors: role of zinc transporters (Zip family) and proinflammatory cytokines.

scientific article

Correction for: LAV-BPIFB4 associates with reduced frailty in humans and its transfer prevents frailty progression in old mice

scientific article published on 25 October 2019

Cu to Zn ratio, physical function, disability, and mortality risk in older elderly (ilSIRENTE study).

scientific article published on 5 May 2011

DNA hydroxymethylation levels are altered in blood cells from Down syndrome persons enrolled in the MARK-AGE project

scientific article published on 21 October 2017

Different transcriptional profiling between senescent and non-senescent human coronary artery endothelial cells (HCAECs) by Omeprazole and Lansoprazole treatment

scientific article

Differential effects of in vitro zinc treatment on gene expression in peripheral blood mononuclear cells derived from young and elderly individuals.

scientific article published in December 2007

Distinctive modulation of inflammatory and metabolic parameters in relation to zinc nutritional status in adult overweight/obese subjects.

scientific article published on 7 May 2009

Dysfunctional macrophages in Alzheimer Disease: another piece of the "macroph-aging" puzzle?

scientific article published on 5 August 2017

Editorial: Therapeutic Modulators of Cellular Senescence: Common Targets in Cancer And Aging

scientific article published in January 2016

Effect of 6-month caloric restriction on Cu bound to ceruloplasmin in adult overweight subjects

scientific article published on 6 May 2015

Effect of ZIP2 Gln/Arg/Leu (rs2234632) polymorphism on zinc homeostasis and inflammatory response following zinc supplementation.

scientific article published in November 2015

Effect of hyperglycemia on the number of CD117+ progenitor cells and their differentiation toward endothelial progenitor cells in young and old ages

scientific article

Effect of improved zinc status on T helper cell activation and TH1/TH2 ratio in healthy elderly individuals

scientific article published on 01 October 2006

Effect of zinc on cellular poly(ADP-ribosyl)ation capacity

scientific article published on 09 October 2007

Effect of zinc supplementation on plasma IL-6 and MCP-1 production and NK cell function in healthy elderly: interactive influence of +647 MT1a and -174 IL-6 polymorphic alleles

scientific article

Effects of human Toll-like receptor 1 polymorphisms on ageing.

scientific article published on 7 February 2013

Effects of interleukin-6 -174C/G and metallothionein 1A +647A/C single-nucleotide polymorphisms on zinc-regulated gene expression in ageing.

scientific article published on 2 February 2008

Effects of zinc supplementation on antioxidant enzyme activities in healthy old subjects.

scientific article published in November 2007

Effects of zinc-fortified drinking skim milk (as functional food) on cytokine release and thymic hormone activity in very old persons: a pilot study.

scientific article

Endogenous Retroelements in Cellular Senescence and Related Pathogenic Processes: Promising Drug Targets in Age-Related Diseases.

scientific article published on 17 May 2015

Epigenetics in ageing and development

scientific article published on 17 May 2018

Exploring the Relevance of Senotherapeutics for the Current SARS-CoV-2 Emergency and Similar Future Global Health Threats

scientific article published on 08 April 2020

FKBP5 rs4713916: A Potential Genetic Predictor of Interindividual Different Response to Inhaled Corticosteroids in Patients with Chronic Obstructive Pulmonary Disease in a Real-Life Setting

scientific article published on 24 April 2019

Gene Expression, Oxidative Stress, and Senescence of Primary Coronary Endothelial Cells Exposed to Postprandial Serum of Healthy Adult and Elderly Volunteers after Oven-Cooked Meat Meals.

scientific article

Health status, blood and anthropometrical indices from Greek old and nonagenarian subjects

scientific article published in October 2006

Implications of impaired zinc homeostasis in diabetic cardiomyopathy and nephropathy.

scientific article

In vitro and in vivo effects of zinc on cytokine signalling in human T cells

scientific article published on 25 December 2007

In vivo effect of alpha-bisabolol, a nontoxic sesquiterpene alcohol, on the induction of spontaneous mammary tumors in HER-2/neu transgenic mice

scientific article published in January 2010

Inducers of Senescence, Toxic Compounds, and Senolytics: The Multiple Faces of Nrf2-Activating Phytochemicals in Cancer Adjuvant Therapy.

scientific article published on 12 February 2018

Inflammation, genes and zinc in Alzheimer's disease.

scientific article published on 08 December 2007

Inflammation, genes and zinc in ageing and age-related diseases.

scientific article published on October 2006

Influence of +1245 A/G MT1A polymorphism on advanced glycation end-products (AGEs) in elderly: effect of zinc supplementation

scientific article

Interrelationship among neutrophil efficiency, inflammation, antioxidant activity and zinc pool in very old age.

scientific article

Involvement of −308 TNF-α and 1267 Hsp70-2 polymorphisms and zinc status in the susceptibility of coronary artery disease (CAD) in old patients

scientific article published on 01 October 2006

Is cellular senescence involved in cystic fibrosis?

scientific article published on 14 February 2019

Is there a possible single mediator in modulating neuroendocrine-thymus interaction in ageing?

scientific article published on February 2013

L-arginine reduces mercury accumulation in thymus of mercury-exposed mice: role of nitric oxide synthase activity and metallothioneins.

scientific article

LAV-BPIFB4 associates with reduced frailty in humans and its transfer prevents frailty progression in old mice

scientific article published on 28 August 2019

Main biomarkers associated with age-related plasma zinc decrease and copper/zinc ratio in healthy elderly from ZincAge study

scientific article

Mediterranean diet and plasma concentration of inflammatory markers in old and very old subjects in the ZINCAGE population study

scientific article published in January 2008

Mercury toxicity: trace element interactions and detoxification activity by L-arginine

scientific article published in July 2007

Metallothionein Downregulation in Very Old Age: A Phenomenon Associated with Cellular Senescence?

Metallothionein isoforms (I+II and III) and interleukin-6 in the hippocampus of old rats: may their concomitant increments lead to neurodegeneration?

scientific article

Metallothioneins, ageing and cellular senescence: a future therapeutic target.

scientific article published on January 2013

Metallothioneins, longevity and cancer: Comment on “Deficiency of metallothionein-1 and -2 genes shortens the lifespan of the 129/Sv mouse strain”

article

Micronutrient (Zn, Cu, Fe)-gene interactions in ageing and inflammatory age-related diseases: implications for treatments

scientific article published on 31 January 2012

Micronutrient-gene interactions related to inflammatory/immune response and antioxidant activity in ageing and inflammation. A systematic review

scientific article published on 02 January 2014

Modulation of Genes Involved in Zinc Homeostasis in Old Low-Grade Atherosclerotic Patients Under Effects of HMG-CoA Reductase Inhibitors

article

Modulators of cellular senescence: mechanisms, promises, and challenges from in vitro studies with dietary bioactive compounds

scientific article

My Mind Project: the effects of cognitive training for elderly-the study protocol of a prospective randomized intervention study.

scientific article

NK and NKT cell functions in immunosenescence

scientific article

New challenges of geriatric cardiology: from clinical to preclinical research ⬇️

scientific article

New trends in biomedical aging research

scientific article published on 01 November 2004

Noninvasive neonatal thymus graft into the axillary cavity extends the lifespan of old mice

scientific article published on 01 April 2010

Normal phase liquid chromatography-electrospray ionization tandem mass spectrometry analysis of phospholipid molecular species in blood mononuclear cells: application to cystic fibrosis.

scientific article

Novel -209A/G MT2A polymorphism in old patients with type 2 diabetes and atherosclerosis: relationship with inflammation (IL-6) and zinc.

scientific article published in December 2005

Nutrient-gene interaction in ageing and successful ageing. A single nutrient (zinc) and some target genes related to inflammatory/immune response

scientific article

Nutritional Factors Modulating Alu Methylation in an Italian Sample from The Mark-Age Study Including Offspring of Healthy Nonagenarians

scientific article published on 06 December 2019

Oxidative Stress in Elderly with Different Cognitive Status: My Mind Project

scientific article published on 01 January 2018

Peripheral Mononuclear Cell Rejuvenation for Senescence Surveillance in Alzheimer Disease

scientific article published on January 1, 2013

Plasma copper/zinc ratio: an inflammatory/nutritional biomarker as predictor of all-cause mortality in elderly population

scientific article published on 10 October 2009

Plasticity of neuroendocrine-thymus interactions during ontogeny and ageing: role of zinc and arginine.

scientific article published on 14 August 2006

Pleiotropic Effects of Tocotrienols and Quercetin on Cellular Senescence: Introducing the Perspective of Senolytic Effects of Phytochemicals.

scientific article

Polymorphisms in MT1a gene coding region are associated with longevity in Italian Central female population

scientific article published in October 2006

Possible new antiaging strategies related to neuroendocrine-immune interactions.

scientific article

Pro-inflammatory genetic background and zinc status in old atherosclerotic subjects.

scientific article published on 19 June 2008

Psychosocial and biochemical interactions in aging: preliminary results from an Italian old sample of "Zincage" project.

scientific article published in January 2007

Psychosocial aspects and zinc status: is there a relationship with successful aging?

scientific article published in January 2006

Recovery from mild Escherichia coli O157:H7 infection in young and aged C57BL/6 mice with intact flora estimated by fecal shedding, locomotor activity and grip strength

scientific article published on 21 December 2018

Reversed Stereochemical Control in the Presence of CeCl(3) and TiCl(4) in the Lewis Acid Mediated Reduction of alpha-Alkyl-beta-keto Esters by Metal Hydrides. A General Methodology for the Diastereoselective Synthesis of syn- and anti-alpha-Alkyl-be

scientific article published on 01 March 1999

Serum copper to zinc ratio: Relationship with aging and health status.

scientific article published on 07 February 2015

Simultaneous evaluation of circulating chemokine and cytokine profiles in elderly subjects by multiplex technology: relationship with zinc status

article published in Biogerontology

Single and three-color flow cytometry assay for intracellular zinc ion availability in human lymphocytes with Zinpyr-1 and double immunofluorescence: Relationship with metallothioneins

scientific article published on 01 October 2006

Speciation of trace elements in human serum by micro anion exchange chromatography coupled with inductively coupled plasma mass spectrometry

scientific article published on 13 November 2011

Survival study of metallothionein-1 transgenic mice and respective controls (C57BL/6J): influence of a zinc-enriched environment.

scientific article

Synaptic and mitochondrial physiopathologic changes in the aging nervous system and the role of zinc ion homeostasis

scientific article

TH1 and TH2 cell polarization increases with aging and is modulated by zinc supplementation

scientific article published on 28 November 2007

The +838 C/G MT2A polymorphism, metals, and the inflammatory/immune response in carotid artery stenosis in elderly people.

scientific article

Torquetenovirus (TTV) load is associated with mortality in Italian elderly subjects

article

Use of mathematical models of survivorship in the study of biomarkers of aging: the role of heterogeneity

scientific article published on 01 September 2001

Vitamin E-gene interactions in aging and inflammatory age-related diseases: implications for treatment. A systematic review

scientific article published on 11 January 2014

Zinc and inflammatory/immune response in aging.

scientific article published on April 2007

Zinc deficiency and IL-6 -174G/C polymorphism in old people from different European countries: effect of zinc supplementation. ZINCAGE study.

scientific article

Zinc dyshomeostasis, ageing and neurodegeneration: implications of A2M and inflammatory gene polymorphisms.

scientific article published on August 2007

Zinc dyshomeostasis: a key modulator of neuronal injury.

scientific article

Zinc homeostasis in aging: two elusive faces of the same "metal".

scientific article published in January 2006

Zinc in elderly people: effects of zinc supplementation on psychological dimensions in dependence of IL-6 -174 polymorphism: a Zincage study.

scientific article published in April 2008

Zinc signalling and subcellular distribution: emerging targets in type 2 diabetes

scientific article published on 04 September 2008

Zinc supplementation boosts the stress response in the elderly: Hsp70 status is linked to zinc availability in peripheral lymphocytes.

scientific article

Zinc supplementation can reduce accumulation of cadmium in aged metallothionein transgenic mice

scientific article published on 04 August 2018

Zinc supplementation in the elderly reduces spontaneous inflammatory cytokine release and restores T cell functions

scientific article published on 01 February 2008

Zinc supplementation in the elderly subjects: effect on oxidized protein degradation and repair systems in peripheral blood lymphocytes.

scientific article published on 25 October 2007

Zinc, metallothioneins and immunosenescence.

scientific article published on 28 June 2010

Zinc, metallothioneins and immunosenescence: effect of zinc supply as nutrigenomic approach

scientific article published on 19 April 2011

Zinc, metallothioneins, and longevity--effect of zinc supplementation: zincage study.

scientific article

Zinc, oxidative stress, genetic background and immunosenescence: implications for healthy ageing

scientific article

Zinc-binding proteins (metallothionein and alpha-2 macroglobulin) and immunosenescence.

scientific article published on 9 October 2006

Zinc-bound metallothioneins and immune plasticity: lessons from very old mice and humans.

scientific article

Zinc-gene interaction related to inflammatory/immune response in ageing.

scientific article published on July 2008

Zinc-induced Metallothionein in centenarian offspring from a large European population: the MARK-AGE Project

scientific article

Zinc: dietary intake and impact of supplementation on immune function in elderly.

scientific article published on 6 January 2012

ZnT8 Arg325Trp polymorphism influences zinc transporter expression and cytokine production in PBMCs from patients with diabetes

scientific article published on 22 August 2018

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