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List of works by Alfonso Colombatti

A catalytic antibody programmed for torsional activation of amide bond hydrolysis

scientific article published in July 2003

A novel bcl-1/JH breakpoint from a patient affected by mantle cell lymphoma extends the major translocation cluster

scientific article published on 01 June 2002

A pilot project of a cancer patient library in Italy: results of a customer-satisfaction survey and its products. ⬇️

scientific article published in December 2006

A solid-phase receptor binding assay for 125I-hCG

scientific article published on 01 January 1987

Adhesion to fibronectin promotes the activation of the p125(FAK)/Zap-70complex in human T cells.

scientific article

Age-Related Persistent Clonal Expansions of CD28−Cells: Phenotypic and Molecular TCR Analysis Reveals both CD4+and CD4+CD8+Cells with Identical CDR3 Sequences

scientific article published on 01 October 1998

Alternative splicing of VWFA modules generates variants of type VI collagen alpha 3 chain with a distinctive expression pattern in embryonic chicken tissues and potentially different adhesive function

scientific article published on 01 February 1998

An EMILIN1-negative microenvironment promotes tumor cell proliferation and lymph node invasion.

scientific article published on 24 July 2012

An Unprecedented Catalytic Motif Revealed in the Model Structure of Amide Hydrolyzing Antibody 312d6

article

Analysis of IgV gene mutations in B cell chronic lymphocytic leukaemia according to antigen-driven selection identifies subgroups with different prognosis and usage of the canonical somatic hypermutation machinery

scientific article published in July 2004

Analysis of regulatory regions of Emilin1 gene and their combinatorial contribution to tissue-specific transcription

scientific article published on 10 February 2005

Antiproliferative and apoptotic effects of two new gold(III) methylsarcosinedithiocarbamate derivatives on human acute myeloid leukemia cells in vitro.

scientific article published on March 2007

Basement membrane components in lymphoid follicles: Immunohistochemical demonstration and retationship to the follicular dendritic cell network

scientific article published on 01 October 1989

Bortezomib down-modulates the survival factor interferon regulatory factor 4 in Hodgkin lymphoma cell lines and decreases the protective activity of Hodgkin lymphoma-associated fibroblasts.

scientific article published on 12 June 2013

Can natural antibodies to VIP or VIP-like HIV-1 glycoprotein facilitate prevention and supportive treatment of breast cancer?

article

Clinical-grade quality platelet-rich plasma releasate (PRP-R/SRGF) from CaCl2 -activated platelet concentrates promoted expansion of mesenchymal stromal cells.

scientific article

Diagnostic Exome Sequencing Identifies a Novel Gene, EMILIN1, Associated with Autosomal-Dominant Hereditary Connective Tissue Disease

scientific journal article

Differential Expression of IRS-1 and IRS-2 in Uterine Leiomyosarcomas with Distinct Oncogenic Phenotypes: Lack of Correlation with Downstream Signaling Events.

scientific article

Differential expression of mucins 1-6 in papillary thyroid carcinoma: evidence for transformation-dependent post-translational modifications of MUC1 in situ.

scientific article published in July 2003

Distribution of PG-M/versican variants in human tissues and de novo expression of isoform V3 upon endothelial cell activation, migration, and neoangiogenesis in vitro

scientific article published on 6 September 2002

EMILIN, a component of the elastic fiber and a new member of the C1q/tumor necrosis factor superfamily of proteins

scientific journal article

EMILIN-1 deficiency induces elastogenesis and vascular cell defects

scientific journal article

EMILIN1-α4/α9 integrin interaction inhibits dermal fibroblast and keratinocyte proliferation.

scientific article

EMILIN2 down-modulates the Wnt signalling pathway and suppresses breast cancer cell growth and migration

scientific article published on March 2014

EMILIN2, extracellular matrix protein, as a regulator of the myeloid response in a model of inflammation-induced colon carcinogenesis

scientific article published on 01 June 2017

Effect of endogenous and exogenous murine leukemia virus infection on immunologic response ⬇️

scientific article published on June 1, 1975

Elastic fiber proteins in the glomerular mesangium in vivo and in cell culture

scientific journal article

Emilin1 deficiency causes structural and functional defects of lymphatic vasculature.

scientific article published on 14 April 2008

Expression of CCR5 receptors on Reed-Sternberg cells and Hodgkin lymphoma cell lines: involvement of CCL5/Rantes in tumor cell growth and microenvironmental interactions.

scientific article

Expression of the monomeric 67-kd lamininbinding protein in human lymphomas as defined by MLuC5 monoclonal antibody and paraffin section immunohistochemistry

scientific article published on 01 May 1995

Expression profiles in malignant fibrous histiocytomas: Clues for differentiating ‘spindle cell’ and ‘pleomorphic’ subtypes

scientific article published in January 2008

Extracellular matrix: a matter of life and death.

scientific article published on January 2008

Fibronectin binding promotes a PKC-dependent modulation of NF-kappa B in human T cells

scientific article published on 01 February 1998

Functional osteoclastogenesis: the baseline variability in blood donor precursors is not associated with age and gender

scientific article published on 10 September 2015

Gefitinib inhibits the cross-talk between mesenchymal stem cells and prostate cancer cells leading to tumor cell proliferation and inhibition of docetaxel activity.

scientific article published on May 2013

Genetic characterization of p27(kip1) and stathmin in controlling cell proliferation in vivo.

scientific article

Genomic analysis of collagen and endogenous virus loci in the UCD-200 and 206 lines of chickens, animal models for scleroderma.

scientific article

HCV inhibits antigen processing and presentation and induces oxidative stress response in gastric mucosa

scientific article published on 21 July 2008

Hyaluronan-CD44 interaction hampers migration of osteoclast-like cells by down-regulating MMP-9.

scientific article

IRF4 silencing inhibits Hodgkin lymphoma cell proliferation, survival and CCL5 secretion

scientific article published on 28 November 2010

Ibrutinib Inhibits VLA-4-Dependent Adhesion in CLL-Letter.

scientific article published in July 2016

Identification of Domains Responsible for von Willebrand Factor Type VI Collagen Interaction Mediating Platelet Adhesion under High Flow

scientific article published in Journal of Biological Chemistry

Identification of a mouse gene required for binding of Rauscher MuLV envelope gp70

scientific article published on January 1, 1979

Identification of an active Chi recombinational hot spot within the HIV-1 envelope gene: consequences for development of AIDS vaccines

scientific article published on 01 March 1999

Immunohistochemical distribution of type VI collagen in developing human kidney

scientific article published on 01 May 1996

In silico analysis suggests interaction between Ebola virus and the extracellular matrix

scientific article

In vitro and in vivo evaluation of T and B lymphocyte functions in AKR mice ⬇️

scientific article published on September 1, 1975

Influenza vaccine as prevention for cardiovascular diseases: possible molecular mechanism

scientific article published on 19 July 2014

Inhibitory effect of YC8 leukaemia cell line on in vitro lymphocyte reactivity ⬇️

scientific article published on May 1, 1977

Isolation of cDNA clones corresponding to the Mr = 150,000 subunit of chick type VI collagen

scientific article published on 01 December 1987

Laminin-332 (Laminin-5) is the major motility ligand for B cell chronic lymphocytic leukemia

scientific article published on 11 April 2007

Long non-coding RNAs and cancer: a new frontier of translational research?

scientific article

MMP-13 stimulates osteoclast differentiation and activation in tumour breast bone metastases.

scientific article published on 27 October 2011

MULTIMERIN2 binds VEGF-A primarily via the carbohydrate chains exerting an angiostatic function and impairing tumor growth.

scientific article published on 9 December 2015

MULTIMERIN2 impairs tumor angiogenesis and growth by interfering with VEGF-A/VEGFR2 pathway

scientific article

Monoclonal antibody detection of naphthalene dioxygenase from Pseudomonas aeruginosa 2NR

scientific article published on 01 October 2000

Multimerin-2 maintains vascular stability and permeability

scientific article published on 15 August 2019

Multiple-interactions among EMILIN1 and EMILIN2 N- and C-terminal domains

scientific article published on November 2014

Multivalent proteoglycan modulation of FGF mitogenic responses in perivascular cells.

scientific article published on 4 November 2012

NG2/CSPG4-collagen type VI interplays putatively involved in the microenvironmental control of tumour engraftment and local expansion.

scientific article published on 3 April 2013

NMR-based homology model for the solution structure of the C-terminal globular domain of EMILIN1

scientific article

Neutrophil elastase-dependent cleavage compromises the tumor suppressor role of EMILIN1.

scientific article published on 7 February 2014

Phenotypic heterogeneity of persistent expansions of CD4+ CD8+ T cells

scientific article published on 01 December 1994

Physical activity and natural anti-VIP antibodies: potential role in breast and prostate cancer therapy

scientific article

Preclinical activity of multiple-target gold(III)-dithiocarbamato peptidomimetics in prostate cancer cells and xenografts.

scientific article published on July 2014

Preclinical activity of the liposomal cisplatin lipoplatin in ovarian cancer.

scientific article published on 17 September 2014

Preclinical activity of the repurposed drug auranofin in classical Hodgkin lymphoma.

scientific article published on 30 July 2015

Preclinical evaluation of a new liposomal formulation of cisplatin, lipoplatin, to treat cisplatin-resistant cervical cancer.

scientific article published on 10 September 2013

Preferential locomotion of leukemic cells towards laminin isoforms 8 and 10.

scientific article published in June 2003

Prevention of murine sarcoma virus oncogenesis in offspring of immunized female mice

scientific article

Role of E2F1-cyclin E1-cyclin E2 circuit in human coronary smooth muscle cell proliferation and therapeutic potential of its downregulation by siRNAs.

scientific article published on 25 June 2009

Role of T198 modification in the regulation of p27(Kip1) protein stability and function

scientific article

SERS analysis of serum for detection of early and locally advanced breast cancer

scientific article published on 9 August 2015

SUMOylation regulates p27Kip1 stability and localization in response to TGFβ.

scientific article published on 8 October 2015

Secretion and matrix assembly of recombinant type VI collagen.

scientific article published on June 1995

Self-assembly and supramolecular organization of EMILIN

scientific journal article

Sequence-specific backbone NMR assignments for the C-terminal globular domain of EMILIN-1.

scientific article published in May 2004

Signature of B-CLL with different prognosis by Shrunken centroids of surface antigen expression profiling

scientific article published in July 2005

Stathmin activity influences sarcoma cell shape, motility, and metastatic potential.

scientific article published on 27 February 2008

Stathmin is dispensable for tumor onset in mice

scientific article published on 20 September 2012

Stathmin regulates mutant p53 stability and transcriptional activity in ovarian cancer.

scientific article published on 22 April 2013

Structure, chromosomal localization, and promoter analysis of the human elastin microfibril interfase located proteIN (EMILIN) gene.

scientific article

Surface-antigen expression profiling (SEP) in B-cell chronic lymphocytic leukemia (B-CLL): Identification of markers with prognostic relevance

scientific article published on 8 August 2005

Surface-enhanced Raman spectroscopy of blood plasma and serum using Ag and Au nanoparticles: a systematic study

scientific article

Surface-enhanced Raman spectroscopy of urine for prostate cancer detection: a preliminary study

scientific article published on 20 March 2015

Targeted intraoperative radiotherapy impairs the stimulation of breast cancer cell proliferation and invasion caused by surgical wounding

scientific article

The EMILIN/Multimerin family.

scientific article published on January 2011

The NF-κB inhibitor DHMEQ decreases survival factors, overcomes the protective activity of microenvironment and synergizes with chemotherapy agents in classical Hodgkin lymphoma.

scientific article published on 2 April 2014

The ablation of the matricellular protein EMILIN2 causes defective vascularization due to impaired EGFR-dependent IL-8 production affecting tumor growth.

scientific article published on 27 February 2018

The first intron of the BCR gene contains two minor alternative exons.

scientific article published in December 1995

The human α3b is a `full‐sized' laminin chain variant with a more widespread tissue expression than the truncated α3a ⬇️

scientific article published on November 3, 1997

The inflammatory chemokine CCL5 and cancer progression

scientific article published on 02 January 2014

The role of CD40/CD40L and interferon regulatory factor 4 in Hodgkin lymphoma microenvironment

scientific article published on August 24, 2011

The solution structure of EMILIN1 globular C1q domain reveals a disordered insertion necessary for interaction with the alpha4beta1 integrin

scientific journal article

The tumor suppressor functions of p27(kip1) include control of the mesenchymal/amoeboid transition.

scientific article

beta 1 Integrin-dependent cell adhesion to EMILIN-1 is mediated by the gC1q domain.

scientific article

p27(Kip1)-stathmin interaction influences sarcoma cell migration and invasion

scientific journal article

p27(kip1) functional regulation in human cancer: a potential target for therapeutic designs.

scientific article

p27Kip1 expression inhibits glioblastoma growth, invasion, and tumor-induced neoangiogenesis.

scientific article

p70S6 kinase mediates breast cancer cell survival in response to surgical wound fluid stimulation.

scientific article published on 12 March 2014

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