List of works - Wenbin Xiao

A JAK2/IDH1-mutant MPN clone unmasked by ivosidenib in an AML patient without antecedent MPN

scientific article published on 01 December 2020

A critical role for alpha-synuclein in development and function of T lymphocytes.

scientific article published on 20 October 2015

A minor catalytic activity of Src family kinases is sufficient for maximal activation of mast cells via the high-affinity IgE receptor.

scientific article

Absolute immature platelet count dynamics in diagnosing and monitoring the clinical course of thrombotic thrombocytopenic purpura

scientific article

CRABP-II is a highly sensitive and specific diagnostic molecular marker for pancreatic ductal adenocarcinoma in distinguishing from benign pancreatic conditions

scientific article

CXCL8/CXCR2 signaling mediates bone marrow fibrosis and is a therapeutic target in myelofibrosis

scientific article published on 18 May 2023

Critical role for mast cell Stat5 activity in skin inflammation

scientific article

Detection of septic transfusion reactions to platelet transfusions by active and passive surveillance

scientific article

Diagnosis and classification of hematologic malignancies on the basis of genetics.

scientific article

Divergent clonal evolution of a common precursor to mantle cell lymphoma and classic Hodgkin lymphoma

scientific article published on 13 December 2019

Early divergence of Fc epsilon receptor I signals for receptor up-regulation and internalization from degranulation, cytokine production, and survival

scientific article published on 01 October 2004

Early recovery of circulating immature B cells in B-lymphoblastic leukemia patients after CD19 targeted CAR T cell therapy: A pitfall for minimal residual disease detection

scientific article published on 9 September 2017

Evolution of a chemosensitive core-binding factor AML into an aggressive leukemia with eosinophilic differentiation

scientific article published on 01 July 2018

Hairy cell leukemia expresses programmed death-1

scientific article published on 05 November 2020

Hodgkin lymphoma variant of Richter transformation: morphology, Epstein-Barr virus status, clonality, and survival analysis-with comparison to Hodgkin-like lesion

scientific article published on 13 May 2016

IgE regulation of mast cell survival and function.

scientific article

Immune regulation by phospholipase C-β isoforms.

scientific article published on May 2013

JAK/MAP kinase pathway activation and TP53 mutations in acute leukemia with megakaryocytic and erythroid differentiation.

scientific article

Late stages of hematopoiesis and B cell lymphopoiesis are regulated by α-synuclein, a key player in Parkinson's disease.

scientific article

Loss of ARID1A/BAF250a expression in ovarian endometriosis and clear cell carcinoma

scientific article

Loss of plasmacytoid dendritic cell differentiation is highly predictive for post-induction measurable residual disease and inferior outcomes in acute myeloid leukemia

scientific article published on 06 December 2018

Lyn- and PLC-beta3-dependent regulation of SHP-1 phosphorylation controls Stat5 activity and myelomonocytic leukemia-like disease.

scientific article

MEN1 mutations mediate clinical resistance to menin inhibition

scientific article published on 15 March 2023

Optimal Measurable Residual Disease Testing for Acute Myeloid Leukemia

scientific article published on 18 May 2019

PRMT5 inhibition modulates E2F1 methylation and gene regulatory networks leading to therapeutic efficacy in JAK2V617F mutant MPN

scientific article published on 15 July 2020

Phospholipase C-β in immune cells.

scientific article

Phospholipase C-β3 Regulates FcɛRI-Mediated Mast Cell Activation by Recruiting the Protein Phosphatase SHP-1 ⬇️

scientific article published on June 16, 2011

Pivotal advance: IgE accelerates in vitro development of mast cells and modifies their phenotype.

scientific article published on 13 May 2008

Plasmacytoid dendritic cell expansion defines a distinct subset of RUNX1 mutated acute myeloid leukemia

scientific article published on 01 September 2020

Positive and negative regulation of mast cell activation by Lyn via the FcepsilonRI

scientific journal article

Recurrent somatic JAK3 mutations in NK-cell enteropathy

scientific article published on 05 August 2019

Regulation of dendritic cell maturation and function by Bruton's tyrosine kinase via IL-10 and Stat3.

scholarly article

Regulation of myeloproliferation and M2 macrophage programming in mice by Lyn/Hck, SHIP, and Stat5

scientific article

Regulation of proliferation, survival, differentiation, and activation by the Signaling Platform for SHP-1 phosphatase.

scientific article published on January 2012

Short Stat5-interacting peptide derived from phospholipase C-β3 inhibits hematopoietic cell proliferation and myeloid differentiation

scientific article

Steady increment of immature platelet fraction is suppressed by irradiation in single-donor platelet components during storage

scientific article

The Src family kinase Hck regulates mast cell activation by suppressing an inhibitory Src family kinase Lyn

scientific article

Tumor suppression by phospholipase C-beta3 via SHP-1-mediated dephosphorylation of Stat5.

scientific article

Utilization of CDX2 expression in diagnosing pancreatic ductal adenocarcinoma and predicting prognosis.

scientific article published on 29 January 2014

List of works by Wenbin Xiao

A JAK2/IDH1-mutant MPN clone unmasked by ivosidenib in an AML patient without antecedent MPN

A critical role for alpha-synuclein in development and function of T lymphocytes.

A minor catalytic activity of Src family kinases is sufficient for maximal activation of mast cells via the high-affinity IgE receptor.

Absolute immature platelet count dynamics in diagnosing and monitoring the clinical course of thrombotic thrombocytopenic purpura

CRABP-II is a highly sensitive and specific diagnostic molecular marker for pancreatic ductal adenocarcinoma in distinguishing from benign pancreatic conditions

CXCL8/CXCR2 signaling mediates bone marrow fibrosis and is a therapeutic target in myelofibrosis

Critical role for mast cell Stat5 activity in skin inflammation

Detection of septic transfusion reactions to platelet transfusions by active and passive surveillance

Diagnosis and classification of hematologic malignancies on the basis of genetics.

Divergent clonal evolution of a common precursor to mantle cell lymphoma and classic Hodgkin lymphoma

Early divergence of Fc epsilon receptor I signals for receptor up-regulation and internalization from degranulation, cytokine production, and survival

Early recovery of circulating immature B cells in B-lymphoblastic leukemia patients after CD19 targeted CAR T cell therapy: A pitfall for minimal residual disease detection

Evolution of a chemosensitive core-binding factor AML into an aggressive leukemia with eosinophilic differentiation

Hairy cell leukemia expresses programmed death-1

Hodgkin lymphoma variant of Richter transformation: morphology, Epstein-Barr virus status, clonality, and survival analysis-with comparison to Hodgkin-like lesion

IgE regulation of mast cell survival and function.

Immune regulation by phospholipase C-β isoforms.

JAK/MAP kinase pathway activation and TP53 mutations in acute leukemia with megakaryocytic and erythroid differentiation.

Late stages of hematopoiesis and B cell lymphopoiesis are regulated by α-synuclein, a key player in Parkinson's disease.

Loss of ARID1A/BAF250a expression in ovarian endometriosis and clear cell carcinoma

Loss of plasmacytoid dendritic cell differentiation is highly predictive for post-induction measurable residual disease and inferior outcomes in acute myeloid leukemia

Lyn- and PLC-beta3-dependent regulation of SHP-1 phosphorylation controls Stat5 activity and myelomonocytic leukemia-like disease.

MEN1 mutations mediate clinical resistance to menin inhibition

Optimal Measurable Residual Disease Testing for Acute Myeloid Leukemia

PRMT5 inhibition modulates E2F1 methylation and gene regulatory networks leading to therapeutic efficacy in JAK2V617F mutant MPN

Phospholipase C-β in immune cells.

Phospholipase C-β3 Regulates FcɛRI-Mediated Mast Cell Activation by Recruiting the Protein Phosphatase SHP-1 ⬇️

Pivotal advance: IgE accelerates in vitro development of mast cells and modifies their phenotype.

Plasmacytoid dendritic cell expansion defines a distinct subset of RUNX1 mutated acute myeloid leukemia

Positive and negative regulation of mast cell activation by Lyn via the FcepsilonRI

Recurrent somatic JAK3 mutations in NK-cell enteropathy

Regulation of dendritic cell maturation and function by Bruton's tyrosine kinase via IL-10 and Stat3.

Regulation of myeloproliferation and M2 macrophage programming in mice by Lyn/Hck, SHIP, and Stat5

Regulation of proliferation, survival, differentiation, and activation by the Signaling Platform for SHP-1 phosphatase.

Short Stat5-interacting peptide derived from phospholipase C-β3 inhibits hematopoietic cell proliferation and myeloid differentiation

Steady increment of immature platelet fraction is suppressed by irradiation in single-donor platelet components during storage

The Src family kinase Hck regulates mast cell activation by suppressing an inhibitory Src family kinase Lyn

Tumor suppression by phospholipase C-beta3 via SHP-1-mediated dephosphorylation of Stat5.

Utilization of CDX2 expression in diagnosing pancreatic ductal adenocarcinoma and predicting prognosis.

and mutations are enriched in distinct subgroups of mixed phenotype acute leukemia with T-lineage differentiation