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List of works by Joseph Sparano

A Multigene Expression Assay to Predict Local Recurrence Risk for Ductal Carcinoma In Situ of the Breast ⬇️

scientific article published on May 2, 2013

A Phase 2 Trial of Dasatinib in Patients with Advanced HER2-Positive and/or Hormone Receptor–Positive Breast Cancer ⬇️

scientific article published on September 8, 2011

A new prognostic score for AIDS-related lymphomas in the rituximab-era

scientific article

A phase I trial of gemcitabine administered as a 96-h continuous intravenous infusion in patients with advanced carcinoma and lymphoma

scientific article

A phase I-II study of combined blockade of the ErbB receptor network with trastuzumab and gefitinib in patients with HER2 (ErbB2)-overexpressing metastatic breast cancer

scientific article

A phase II trial of capecitabine in combination with the farnesyltransferase inhibitor tipifarnib in patients with anthracycline-treated and taxane-resistant metastatic breast cancer: an Eastern Cooperative Oncology Group Study (E1103) ⬇️

scientific article published on May 1, 2012

A phase II trial of trastuzumab plus weekly ixabepilone and carboplatin in patients with HER2-positive metastatic breast cancer: an Eastern Cooperative Oncology Group Trial

scientific article

Adjuvant Chemotherapy Guided by a 21-Gene Expression Assay in Breast Cancer

article

Biomarker prediction of chemotherapy-related amenorrhea in premenopausal women with breast cancer participating in E5103.

scientific article

Caveolin-1 mutations in human breast cancer: functional association with estrogen receptor alpha-positive status

scientific article published in June 2006

Cetuximab Plus Chemoradiotherapy in Immunocompetent Patients With Anal Carcinoma: A Phase II Eastern Cooperative Oncology Group-American College of Radiology Imaging Network Cancer Research Group Trial (E3205).

scientific article

Charcot-Marie-Tooth gene, SBF2, associated with taxane-induced peripheral neuropathy in African Americans

scientific article published on 09 October 2016

Chemotherapy in Patients with Anthracycline and Taxane-Pretreated Metastatic Breast Cancer: An Overview ⬇️

scientific article published on March 1, 2013

Chronic thalidomide and chemoembolization for hepatocellular carcinoma

scientific article

Clinical and Genomic Risk to Guide the Use of Adjuvant Therapy for Breast Cancer

scientific article published on 03 June 2019

Comparative clinical benefits of systemic adjuvant therapy for paradigm solid tumors

scientific article

Dasatinib as a Single Agent in Triple-Negative Breast Cancer: Results of an Open-Label Phase 2 Study ⬇️

scientific article published on October 25, 2011

E2112: randomized phase iii trial of endocrine therapy plus entinostat/placebo in patients with hormone receptor-positive advanced breast cancer.

scientific article published on 11 January 2018

Efficacy of the PARP Inhibitor Veliparib with Carboplatin or as a Single Agent in Patients with Germline BRCA1- or BRCA2-Associated Metastatic Breast Cancer: California Cancer Consortium Trial NCT01149083.

scientific article

Enriched transcription factor signatures in triple negative breast cancer indicates possible targeted therapies with existing drugs

scientific article published on 15 May 2015

Evaluation of serum Amphiregulin levels in breast cancer patients and cancer-free controls

scientific article published on 08 September 2013

Expression, Clinical Significance, and Receptor Identification of the Newest B7 Family Member HHLA2 Protein

scientific article published on 30 December 2014

GRB7 is required for triple-negative breast cancer cell invasion and survival ⬇️

scientific article published on October 18, 2011

Genome-Wide Association Studies for Taxane-Induced Peripheral Neuropathy in ECOG-5103 and ECOG-1199.

scientific article

Genome-Wide Association Study for Anthracycline-Induced Congestive Heart Failure

scientific article published on 19 December 2016

High expression of class III β-tubulin predicts good response to neoadjuvant taxane and doxorubicin/cyclophosphamide-based chemotherapy in estrogen receptor-negative breast cancer

scientific article

How Do I Treat Inflammatory Breast Cancer? ⬇️

scientific article published on March 1, 2013

Human Immunodeficiency Virus/AIDS, Human Papillomavirus, and Anal Cancer

scientific article published on January 2017

Human T cell leukemia virus reactivation with progression of adult T-cell leukemia-lymphoma

scientific article

Human immunodeficiency virus associated lymphoma

scientific article

Immunophenotypic analysis of AIDS-related diffuse large B-cell lymphoma and clinical implications in patients from AIDS Malignancies Consortium clinical trials 010 and 034

scientific article

Impact of Genetic Ancestry on Outcomes in ECOG-ACRIN-E5103

scientific article published on 21 August 2017

Increased expression of tumor proliferation genes in Hispanic women with early-stage breast cancer

scientific article published on 25 September 2014

Inhibiting Ras signaling in the therapy of breast cancer

scientific article

Ixabepilone plus capecitabine in metastatic breast cancer patients with reduced performance status previously treated with anthracyclines and taxanes: a pooled analysis by performance status of efficacy and safety data from 2 phase III studies

scientific article

Ixabepilone-associated peripheral neuropathy: data from across the phase II and III clinical trials

scientific article

Joseph Sparano on gene expression assays for breast cancer

scientific article published in September 2011

Learning from big data: are we undertreating older women with high-risk breast cancer?

scientific article published on 8 June 2016

Long-Term Follow-Up of the E1199 Phase III Trial Evaluating the Role of Taxane and Schedule in Operable Breast Cancer

scientific article published on 15 June 2015

Maintenance of clinical efficacy after dose reduction of ixabepilone plus capecitabine in patients with anthracycline- and taxane-resistant metastatic breast cancer: a retrospective analysis of pooled data from 2 phase III randomized clinical trials

scientific article

Metastatic carcinoma: an unusual cause of focal brain lesions in HIV infection.

scientific article published on November 2003

Mitotic counts in breast cancer after neoadjuvant systemic chemotherapy and development of metastatic disease ⬇️

scientific article published on February 17, 2013

Molecular markers of risk of subsequent invasive breast cancer in women with ductal carcinoma in situ: protocol for a population-based cohort study

publication published on 26 October 2021

Neoadjuvant chemotherapy induces breast cancer metastasis through a TMEM-mediated mechanism.

scientific article published on July 2017

Obesity at diagnosis is associated with inferior outcomes in hormone receptor‐positive operable breast cancer ⬇️

scientific article published on August 27, 2012

Paradigms and Controversies in the Treatment of HIV-Related Burkitt Lymphoma ⬇️

scientific article published on April 18, 2012

Phase 2 trial of infusional cyclophosphamide, doxorubicin, and etoposide in patients with poor-prognosis, intermediate-grade non-Hodgkin lymphoma: an Eastern Cooperative Oncology Group trial (E3493).

scientific article

Phase 2 trial of the histone deacetylase inhibitor romidepsin for the treatment of refractory multiple myeloma

scientific article

Phase I-II study of the farnesyl transferase inhibitor tipifarnib plus sequential weekly paclitaxel and doxorubicin-cyclophosphamide in HER2/neu-negative inflammatory carcinoma and non-inflammatory estrogen receptor-positive breast carcinoma

scientific article published on 26 September 2013

Phase II Study of Gemcitabine, Carboplatin, and Iniparib As Neoadjuvant Therapy for Triple-Negative and BRCA1/2 Mutation-Associated Breast Cancer With Assessment of a Tumor-Based Measure of Genomic Instability: PrECOG 0105

scientific article published on 6 April 2015

Phase II trial of bortezomib alone or in combination with irinotecan in patients with adenocarcinoma of the gastroesophageal junction or stomach

scientific article

Phase II trial of infusional cyclophosphamide, doxorubicin, and etoposide in patients with HIV-associated non-Hodgkin's lymphoma: an Eastern Cooperative Oncology Group Trial (E1494).

scientific article

Phase II trial of infusional cyclophosphamide, idarubicin, and etoposide in poor prognosis non-Hodgkin's lymphoma

scientific article

Phase II trial of pegylated liposomal doxorubicin plus docetaxel with and without trastuzumab in metastatic breast cancer: Eastern Cooperative Oncology Group trial E3198.

scientific article

Phase II trial of saracatinib (AZD0530), an oral SRC-inhibitor for the treatment of patients with hormone receptor-negative metastatic breast cancer

scientific article published on 3 May 2011

Phase II trial of the ribonucleotide reductase inhibitor 3-aminopyridine-2-carboxaldehydethiosemicarbazone plus gemcitabine in patients with advanced biliary tract cancer

scientific article

Phase II trial of tipifarnib plus neoadjuvant doxorubicin-cyclophosphamide in patients with clinical stage IIB-IIIC breast cancer

scientific article (publication date: 15 April 2009)

Phase III comparison of tamoxifen versus tamoxifen plus ovarian function suppression in premenopausal women with node-negative, hormone receptor-positive breast cancer (E-3193, INT-0142): a trial of the Eastern Cooperative Oncology Group

scientific article

Phase I–II study of vorinostat plus paclitaxel and bevacizumab in metastatic breast cancer: evidence for vorinostat-induced tubulin acetylation and Hsp90 inhibition in vivo ⬇️

scientific article published on December 27, 2011

Pilot study evaluating the interaction between paclitaxel and protease inhibitors in patients with human immunodeficiency virus-associated Kaposi's sarcoma: an Eastern Cooperative Oncology Group (ECOG) and AIDS Malignancy Consortium (AMC) trial

scientific article

Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer

scientific article published on 12 May 2020

Pooled analysis of AIDS malignancy consortium trials evaluating rituximab plus CHOP or infusional EPOCH chemotherapy in HIV-associated non-Hodgkin lymphoma

scientific article published on 16 December 2011

Predicting cancer therapy-induced cardiotoxicity: the role of troponins and other markers

scientific article

Prognostic and predictive value of tumor vascular endothelial growth factor gene amplification in metastatic breast cancer treated with paclitaxel with and without bevacizumab; results from ECOG 2100 trial

scientific article

Prognostic gene expression assays in breast cancer: are two better than one?

scientific article published on 22 May 2018

Prognostic value of tumor-infiltrating lymphocytes in triple-negative breast cancers from two phase III randomized adjuvant breast cancer trials: ECOG 2197 and ECOG 1199.

scientific article

Progress in adjuvant chemotherapy for breast cancer: an overview

scientific article (publication date: 2015)

Prospective Validation of a 21-Gene Expression Assay in Breast Cancer

scientific article (publication date: 19 November 2015)

Race and hormone receptor-positive breast cancer outcomes in a randomized chemotherapy trial

scientific article published on 16 January 2012

Randomized Phase II Study of Ramucirumab or Icrucumab in Combination with Capecitabine in Patients with Previously Treated Locally Advanced or Metastatic Breast Cancer

scientific article published on 20 February 2017

Randomized phase II trial of fulvestrant alone or in combination with bortezomib in hormone receptor-positive metastatic breast cancer resistant to aromatase inhibitors: a New York Cancer Consortium trial

scientific article

Randomized phase III trial of ixabepilone plus capecitabine versus capecitabine in patients with metastatic breast cancer previously treated with an anthracycline and a taxane

scientific article

Randomized phase III trial of marimastat versus placebo in patients with metastatic breast cancer who have responding or stable disease after first-line chemotherapy: Eastern Cooperative Oncology Group trial E2196

scientific article

Randomized trial of paclitaxel versus pegylated liposomal doxorubicin for advanced human immunodeficiency virus-associated Kaposi sarcoma: evidence of symptom palliation from chemotherapy

scientific article

Relationship between Quantitative GRB7 RNA Expression and Recurrence after Adjuvant Anthracycline Chemotherapy in Triple-Negative Breast Cancer ⬇️

scientific article published on September 20, 2011

Rituximab does not improve clinical outcome in a randomized phase 3 trial of CHOP with or without rituximab in patients with HIV-associated non-Hodgkin lymphoma: AIDS-Malignancies Consortium Trial 010.

scientific article published on 24 May 2005

Rituximab plus concurrent infusional EPOCH chemotherapy is highly effective in HIV-associated B-cell non-Hodgkin lymphoma

scientific article

Safety and Preliminary Efficacy of Vorinostat With R-EPOCH in High-risk HIV-associated Non-Hodgkin's Lymphoma (AMC-075).

scientific article published on 2 February 2018

Safety and efficacy of an oncolytic viral strategy using bortezomib with ICE/R in relapsed/refractory HIV-positive lymphomas

article

Structure and cancer immunotherapy of the B7 family member B7x

scientific article

T cell coinhibition and immunotherapy in human breast cancer ⬇️

scientific article published on October 1, 2012

TOP2A RNA expression and recurrence in estrogen receptor-positive breast cancer ⬇️

scientific article published on June 16, 2012

Tailoring Adjuvant Therapy for Breast Cancer in the Elderly: Room for Improvement.

scientific article published on 30 November 2016

Targeting insulin inhibition as a metabolic therapy in advanced cancer: A pilot safety and feasibility dietary trial in 10 patients ⬇️

scientific article published on July 26, 2012

Taxanes: impact on breast cancer therapy

scientific article published on May 2014

Toronto Workshop on Late Recurrence in Estrogen Receptor-Positive Breast Cancer: Part 1: Late Recurrence: Current Understanding, Clinical Considerations

scientific article published on 10 August 2019

Toronto Workshop on Late Recurrence in Estrogen Receptor-Positive Breast Cancer: Part 2: Approaches to Predict and Identify Late Recurrence, Research Directions

scientific article published on 10 August 2019

Tumor microenvironment of metastasis and risk of distant metastasis of breast cancer.

scientific article

Two may be better than one: PD-1/PD-L1 blockade combination approaches in metastatic breast cancer

scientific article published on 08 October 2019

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