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List of works by Michael Delves

3-Hydroxy-N'-arylidenepropanehydrazonamides with Halo-Substituted Phenanthrene Scaffolds Cure P. berghei Infected Mice When Administered Perorally

scientific article published on 27 June 2017

8-Aminoquinolines with an Aminoxyalkyl Side Chain Exert in vitro Dual-Stage Antiplasmodial Activity

scientific article published on 14 January 2019

A GFP-actin reporter line to explore microfilament dynamics across the malaria parasite lifecycle

scientific article published on 25 November 2011

A Malaria Transmission-Blocking (+)-Usnic Acid Derivative Prevents Plasmodium Zygote-to-Ookinete Maturation in the Mosquito Midgut.

scientific article published on 17 November 2016

A high throughput screen for next-generation leads targeting malaria parasite transmission

scientific article published in Nature Communications

A high-throughput assay for the identification of malarial transmission-blocking drugs and vaccines

scientific article published on 27 September 2012

A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria

scientific article

A male and female gametocyte functional viability assay to identify biologically relevant malaria transmission-blocking drugs

scientific article

A novel multiple-stage antimalarial agent that inhibits protein synthesis

scientific article (publication date: 18 June 2015)

A semi-automated method for counting fluorescent malaria oocysts increases the throughput of transmission blocking studies

scientific article

A tetraoxane-based antimalarial drug candidate that overcomes PfK13-C580Y dependent artemisinin resistance

scientific article published on 24 May 2017

Adaptation of targeted nanocarriers to changing requirements in antimalarial drug delivery

scientific article published on 05 October 2016

Allele-Specific Isothermal Amplification Method Using Unmodified Self-Stabilizing Competitive Primers

scientific article published on 02 October 2018

An essential role of the basal body protein SAS-6 in Plasmodium male gamete development and malaria transmission

scientific article (publication date: February 2015)

An inexpensive open source 3D-printed membrane feeder for human malaria transmission studies

article

Antimalarial Transmission-Blocking Interventions: Past, Present, and Future

article

Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase.

scientific article

Assessing transmission blockade in Plasmodium spp.

scientific article published in January 2013

Assessment of therapeutic responses to gametocytocidal drugs in Plasmodium falciparum malaria

scientific article

Changes in metabolic phenotypes of Plasmodium falciparum in vitro cultures during gametocyte development

scientific article

Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose-Efficacy Modeling

scientific article

Corrigendum: A novel multiple-stage antimalarial agent that inhibits protein synthesis

scientific article published on 25 May 2016

Discovery of a Quinoline-4-carboxamide Derivative with a Novel Mechanism of Action, Multistage Antimalarial Activity, and Potent in Vivo Efficacy

scientific article published on 10 September 2016

Failure of in vitro differentiation of Plasmodium falciparum gametocytes into ookinetes arises because of poor gamete fertilisation

Generation of quinolone antimalarials targeting the Plasmodium falciparum mitochondrial respiratory chain for the treatment and prophylaxis of malaria

scientific article

Hexahydroquinolines are antimalarial candidates with potent blood-stage and transmission-blocking activity

scientific article published on 14 August 2017

Histone methyltransferase inhibitors are orally bioavailable, fast-acting molecules with activity against different species causing malaria in humans

scientific article

Hundreds of dual-stage antimalarial molecules discovered by a functional gametocyte screen

scientific article

Imaging-based high-throughput screening assay to identify new molecules with transmission-blocking potential against Plasmodium falciparum female gamete formation

scientific article published on 23 March 2015

Kinesin-8B controls basal body function and flagellum formation and is key to malaria transmission.

scientific article published in August 2019

Laboratory maintenance of rodent malaria parasites

scientific article

Lead clinical and preclinical antimalarial drugs can significantly reduce sporozoite transmission to vertebrate populations.

scientific article

Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis

scientific article published on 20 March 2019

Male and female Plasmodium falciparum mature gametocytes show different responses to antimalarial drugs

scientific article published on 29 April 2013

Measuring the blockade of malaria transmission--an analysis of the Standard Membrane Feeding Assay

scientific article published on 27 September 2012

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond

scientific article (publication date: July 2016)

Open Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles

scientific article published on 14 September 2016

Plasmodium cell biology should inform strategies used in the development of antimalarial transmission-blocking drugs

scientific article published on December 2012

Plasmodium male development gene-1 (mdv-1) is important for female sexual development and identifies a polarised plasma membrane during zygote development

scientific article published on 24 December 2008

Polyamidoamine Nanoparticles for the Oral Administration of Antimalarial Drugs.

scientific article

Pyrazoleamide compounds are potent antimalarials that target Na+ homeostasis in intraerythrocytic Plasmodium falciparum

scientific article

Quantitative analysis of Plasmodium ookinete motion in three dimensions suggests a critical role for cell shape in the biomechanics of malaria parasite gliding motility

scientific article

Quinolone-3-diarylethers: a new class of antimalarial drug.

scientific article published in March 2013

Routine in vitro culture of P. falciparum gametocytes to evaluate novel transmission-blocking interventions.

scientific article published on 18 August 2016

Spatial localisation of actin filaments across developmental stages of the malaria parasite

scientific article (publication date: 2012)

Targeting the parasite in the mosquito: rationale and practicality.

scientific article published on 15 October 2012

The Plasmodium berghei sexual stage antigen PSOP12 induces anti-malarial transmission blocking immunity both in vivo and in vitro

scientific article (publication date: 9 January 2015)

The activities of current antimalarial drugs on the life cycle stages of Plasmodium: a comparative study with human and rodent parasites

scientific article

The antimalarial screening landscape-looking beyond the asexual blood stage

scientific article published on 12 March 2019

The design and interpretation of laboratory assays measuring mosquito transmission of Plasmodium

scientific article published on 11 September 2012

Use of Plasmodium falciparum culture-adapted field isolates for in vitro exflagellation-blocking assay

scientific article published on 4 June 2015

Use of a selective inhibitor to define the chemotherapeutic potential of the plasmodial hexose transporter in different stages of the parasite's life cycle

scientific article

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