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List of works by Suzanne Kaptein

3',5'Di-O-trityluridine inhibits in vitro flavivirus replication

scientific article published on 5 March 2013

3′,5′di-O-Trityluridine Inhibits Flavivirus (Dengue and Yellow Fever Virus) Replication and Targets the Viral RNA Dependent RNA Polymerase

article by Tine De Burghgraeve et al published May 2011 in Antiviral Research

A Dengue type 2 reporter virus assay amenable to high-throughput screening

scientific article published on 05 September 2020

A Derivate of the Antibiotic Doxorubicin Inhibits Dengue and Yellow Fever Virus Replication In Vitro

article by Suzanne Kaptein et al published May 2008 in Antiviral Research

A Viral Polymerase Inhibitor Reduces Zika Virus Replication in the Reproductive Organs of Male Mice. ⬇️

scientific article

A derivate of the antibiotic doxorubicin is a selective inhibitor of dengue and yellow fever virus replication in vitro

scientific article

A pan-serotype dengue virus inhibitor targeting the NS3–NS4B interaction

scientific article published on 6 October 2021

A single-dose live-attenuated YF17D-vectored SARS-CoV-2 vaccine candidate

scientific article published on 01 December 2020

A yellow fever-Zika chimeric virus vaccine candidate protects against Zika infection and congenital malformations in mice

scientific article published on 13 December 2018

Aminopurine and aminoquinazoline scaffolds for development of potential dengue virus inhibitors

scientific article published on 5 October 2016

An analogue of the antibiotic teicoplanin prevents flavivirus entry in vitro

scientific article

Animal models for COVID-19

scientific article published on 23 September 2020

Antibody-dependent enhancement of dengue virus infection is inhibited by SA-17, a doxorubicin derivative

scientific article published on 28 August 2013

Antiviral Activity of Carbohydrate Binding Agents (CBAS) and the Role of DC-SIGN in Dengue Virus and HIV Infection

article

Antiviral activity of carbohydrate-binding agents and the role of DC-SIGN in dengue virus infection

scientific article

Antiviral treatment of chronic hepatitis B virus (HBV) infections

scientific article

Antiviral treatment of chronic hepatitis B virus infections: the past, the present and the future

scientific article published on January 2008

Broad antiviral activity of carbohydrate-binding agents against the four serotypes of dengue virus in monocyte-derived dendritic cells

scientific article

Cover Feature: Identification of Broad-Spectrum Dengue/Zika Virus Replication Inhibitors by Functionalization of Quinoline and 2,6-Diaminopurine Scaffolds (ChemMedChem 14/2018)

scholarly article by Suzanne J. F. Kaptein et al published 18 July 2018 in ChemMedChem

Debio 025, a cyclophilin binding molecule, is highly efficient in clearing hepatitis C virus (HCV) replicon-containing cells when used alone or in combination with specifically targeted antiviral therapy for HCV (STAT-C) inhibitors

scientific article

Design, Synthesis and Discovery of N,N'-Carbazoyl-aryl-urea Inhibitors of Zika NS5 Methyltransferase and Virus Replication

scientific article published on 07 January 2020

Design, synthesis, optimization and antiviral activity of a class of hybrid dengue virus E protein inhibitors

scientific article published on 2 March 2015

Discovery of Indole Derivatives as Novel and Potent Dengue Virus Inhibitors

Discovery of Indole Derivatives as Novel and Potent Dengue Virus Inhibitors

scholarly article by Dorothée Bardiot et al published 27 August 2018 in Journal of Medicinal Chemistry

Discovery of Multitarget Antivirals Acting on Both the Dengue Virus NS5-NS3 Interaction and the Host Src/Fyn Kinases

scientific article published on 15 June 2015

Favipiravir at high doses has potent antiviral activity in SARS-CoV-2-infected hamsters, whereas hydroxychloroquine lacks activity

scientific article

Favipiravir inhibits in vitro Usutu virus replication and delays disease progression in an infection model in mice

scientific article published in 2018

Favipiravir inhibits in vitro Usutu virus replication and delays disease progression in an infection model in mice

Generation of polyclonal antibodies directed against G protein-coupled receptors using electroporation-aided DNA immunization

scientific article published in July 2008

Human stem cell-derived hepatocyte-like cells support Zika virus replication and provide a relevant model to assess the efficacy of potential antivirals

scientific article published in PLoS ONE

Identification of a new dengue virus inhibitor that targets the viral NS4B protein and restricts genomic RNA replication

scientific article

Identification of broad-spectrum dengue/Zika virus replication inhibitors by functionalization of quinoline and 2,6-diaminopurine scaffolds

scientific article

In search of Flavivirus inhibitors part 2: tritylated, diphenylmethylated and other alkylated nucleoside analogues

scientific article published on 10 February 2014

In vitro Anti-hepatitis C Virus (HCV) Activities and Resistance Profile of Debio 025, A Non-immunosuppressive Cyclophilin Binding Molecule

scientific article published in 2009

Ivermectin is a potent inhibitor of flavivirus replication specifically targeting NS3 helicase activity: new prospects for an old drug

scientific article

Rat cytomegalovirus open reading frame R44 is an early-late gene that encodes a nuclear protein ⬇️

scientific article published on January 1, 2001

Reaching beyond HIV/HCV: nelfinavir as a potential starting point for broad-spectrum protease inhibitors against dengue and chikungunya virus

article

Recent African strains of Zika virus display higher transmissibility and fetal pathogenicity than Asian strains

scientific article

Replication of the Zika virus in different iPSC-derived neuronal cells and implications to assess efficacy of antivirals

scientific article published on 20 July 2017

Reverse engineering synthetic antiviral amyloids

scientific article published on 05 June 2020

STAT2 signaling as double-edged sword restricting viral dissemination but driving severe pneumonia in SARS-CoV-2 infected hamsters

scientific article published on 24 April 2020

STAT2 signaling restricts viral dissemination but drives severe pneumonia in SARS-CoV-2 infected hamsters

scientific article published on 17 November 2020

Scaffold Morphing Approach To Expand the Toolbox of Broad-Spectrum Antivirals Blocking Dengue/Zika Replication

scientific article published on 23 January 2019

Small-molecule inhibitors of TBK1 serve as an adjuvant for a plasmid-launched live-attenuated yellow fever vaccine

scientific article published on 23 June 2020

Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches

scientific article published on 11 January 2022

Synthesis and evaluation of imidazole-4,5- and pyrazine-2,3-dicarboxamides targeting dengue and yellow fever virus

scientific article published on 22 September 2014

Synthetic strategy and antiviral evaluation of diamide containing heterocycles targeting dengue and yellow fever virus

scientific article

The Maastricht Strain and England Strain of Rat Cytomegalovirus Represent Different Betaherpesvirus Species Rather Than Strains

article

The Viral Polymerase Inhibitor 7-Deaza-2'-C-Methyladenosine Is a Potent Inhibitor of In Vitro Zika Virus Replication and Delays Disease Progression in a Robust Mouse Infection Model

scientific article

The anti-malaria drug artesunate inhibits replication of cytomegalovirus in vitro and in vivo.

scientific article published on 21 November 2005

The legacy of ZikaPLAN: a transnational research consortium addressing Zika

scientific article published in 2021

The r131 gene of rat cytomegalovirus encodes a proinflammatory CC chemokine homolog which is essential for the production of infectious virus in the salivary glands.

scientific article published on August 2004

The rat cytomegalovirus R33-encoded G protein-coupled receptor signals in a constitutive fashion

scientific article

The rat cytomegalovirus R78 G protein-coupled receptor gene is required for production of infectious virus in the spleen

scientific article published in September 2003

The rat cytomegalovirus homologue of parvoviral rep genes, r127, encodes a nuclear protein with single- and double-stranded DNA-binding activity that is dispensable for virus replication

scientific article

Towards antiviral therapies for treating dengue virus infections.

scientific article published on 28 June 2016

ZikaPLAN: addressing the knowledge gaps and working towards a research preparedness network in the Americas

scientific article published on 01 January 2019

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