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List of works by Dennis R. Burton

2G12-expressing B cell lines may aid in HIV carbohydrate vaccine design strategies

scientific article published on 5 December 2012

A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic β-Hairpin Structure

scientific article

A Conformational Switch in Human Immunodeficiency Virus gp41 Revealed by the Structures of Overlapping Epitopes Recognized by Neutralizing Antibodies

scientific article

A Meta-analysis of Passive Immunization Studies Shows that Serum-Neutralizing Antibody Titer Associates with Protection against SHIV Challenge

scientific article published on 01 September 2019

A Neutralizing Antibody Recognizing Primarily N-Linked Glycan Targets the Silent Face of the HIV Envelope.

scientific article published on 7 March 2018

A Plea for Justice for Jailed Medical Workers

scientific article published in Science

A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield

scientific article

A Prominent Site of Antibody Vulnerability on HIV Envelope Incorporates a Motif Associated with CCR5 Binding and Its Camouflaging Glycans.

scientific article published on July 2016

A Protective Monoclonal Antibody Targets a Site of Vulnerability on the Surface of Rift Valley Fever Virus

scientific article published on 01 December 2018

A broadly neutralizing human monoclonal antibody exhibits in vivo efficacy against both human metapneumovirus and respiratory syncytial virus

scientific article

A change in the conformation of prions accompanies the emergence of a new prion strain.

scientific article

A comparative immunogenicity study of HIV-1 virus-like particles bearing various forms of envelope proteins, particles bearing no envelope and soluble monomeric gp120.

scientific article

A directed molecular evolution approach to improved immunogenicity of the HIV-1 envelope glycoprotein

scientific article (publication date: 2011)

A dominant role for CD8+-T-lymphocyte selection in simian immunodeficiency virus sequence variation

scientific article published on December 2004

A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses

scientific article published on 31 October 2019

A genetically humanized mouse model for hepatitis C virus infection

scientific article

A glycoconjugate antigen based on the recognition motif of a broadly neutralizing human immunodeficiency virus antibody, 2G12, is immunogenic but elicits antibodies unable to bind to the self glycans of gp120

scientific article published on 23 April 2008

A human inferred germline antibody binds to an immunodominant epitope and neutralizes Zika virus

scientific article

A limited number of antibody specificities mediate broad and potent serum neutralization in selected HIV-1 infected individuals

scientific article

A native-like SOSIP.664 trimer based on an HIV-1 subtype B env gene

scientific article

A natural mutation between SARS-CoV-2 and SARS-CoV determines neutralization by a cross-reactive antibody

scientific article published on 04 December 2020

A nonfucosylated variant of the anti-HIV-1 monoclonal antibody b12 has enhanced FcγRIIIa-mediated antiviral activity in vitro but does not improve protection against mucosal SHIV challenge in macaques

scientific article

A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity

scientific article

A novel human antibody against human immunodeficiency virus type 1 gp120 is V1, V2, and V3 loop dependent and helps delimit the epitope of the broadly neutralizing antibody immunoglobulin G1 b12.

scientific article

A panel of IgG1 b12 variants with selectively diminished or enhanced affinity for Fcγ receptors to define the role of effector functions in protection against HIV.

scientific article published on 17 August 2011

A peptide inhibitor of HIV-1 neutralizing antibody 2G12 is not a structural mimic of the natural carbohydrate epitope on gp120

scientific article

A recombinant human monoclonal antibody to human metapneumovirus fusion protein that neutralizes virus in vitro and is effective therapeutically in vivo

scientific article

A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples

scientific article

A short segment in the HIV-1 gp120 V1/V2 region is a major determinant of neutralization resistance to PG9-like antibodies.

scientific article published on 13 September 2012

A short segment of the HIV-1 gp120 V1/V2 region is a major determinant of resistance to V1/V2 neutralizing antibodies

scientific article

A welcome burst of human antibodies.

scientific article

AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges

scientific article

AI-guided discovery of the invariant host response to viral pandemics

scientific article published on 22 September 2020

AIDS/HIV. A boost for HIV vaccine design

scientific article

Accelerating next-generation vaccine development for global disease prevention

scientific article published on May 2013

Access of antibody molecules to the conserved coreceptor binding site on glycoprotein gp120 is sterically restricted on primary human immunodeficiency virus type 1

scientific article

Advancing an HIV vaccine; advancing vaccinology

article

Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans.

scientific article published on December 2015

An AIDS vaccine: no time to give up

scientific article published on 01 November 2004

An Automated Fluorescence-Based Method to Isolate Bone Marrow-Derived Plasma Cells from Rhesus Macaques Using SIVmac239 SOSIP.664

scientific article published on 05 August 2020

An Engineered Antibody with Broad Protective Efficacy in Murine Models of SARS and COVID-19

scientific article published on 17 November 2020

An HIV-1 antibody from an elite neutralizer implicates the fusion peptide as a site of vulnerability

scientific article

An MPER antibody neutralizes HIV-1 using germline features shared among donors

scientific article published on 26 November 2019

An affinity-enhanced neutralizing antibody against the membrane-proximal external region of human immunodeficiency virus type 1 gp41 recognizes an epitope between those of 2F5 and 4E10

scientific article

An aptamer that neutralizes R5 strains of HIV-1 binds to core residues of gp120 in the CCR5 binding site

scientific article

An engineered mutant of HIV-1 gp120 formulated with adjuvant Quil A promotes elicitation of antibody responses overlapping the CD4-binding site ⬇️

scientific article published on 04 December 2011

Analysis of the neutralization breadth of the anti-V3 antibody F425-B4e8 and re-assessment of its epitope fine specificity by scanning mutagenesis

scientific article published on 6 April 2007

Another HIV vaccine failure: where to next?

scientific article published on December 2013

Anti-HIV B Cell lines as candidate vaccine biosensors

scientific article published on 12 October 2012

Anti-human immunodeficiency virus type 1 (HIV-1) antibodies 2F5 and 4E10 require surprisingly few crucial residues in the membrane-proximal external region of glycoprotein gp41 to neutralize HIV-1.

scientific article published on January 2005

Antibodies to West Nile virus: a double-edged sword

scientific article

Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike

scientific article

Antibodies, viruses and vaccines

scientific article

Antibody 2G12 Recognizes Di-Mannose Equivalently in Domain- and Nondomain-Exchanged Forms but Only Binds the HIV-1 Glycan Shield if Domain Exchanged

scientific article

Antibody Conjugation Approach Enhances Breadth and Potency of Neutralization of Anti-HIV-1 Antibodies and CD4-IgG ⬇️

scientific article published on February 20, 2013

Antibody Engineering & Therapeutics 2015: The Antibody Society's annual meeting December 7-10, 2015, San Diego, CA.

scientific article published on 30 September 2015

Antibody Engineering & Therapeutics 2016: The Antibody Society's annual meeting, December 11-15, 2016, San Diego, CA

scientific article published on 24 August 2016

Antibody barriers to going viral

scientific article published on 23 August 2019

Antibody domain exchange is an immunological solution to carbohydrate cluster recognition

scientific article

Antibody elicited against the gp41 N-heptad repeat (NHR) coiled-coil can neutralize HIV-1 with modest potency but non-neutralizing antibodies also bind to NHR mimetics.

scientific article

Antibody engineering and therapeutics conference. The annual meeting of the antibody society, Huntington Beach, CA, December 7-11, 2014.

scientific article published on January 2014

Antibody recognition of a carbohydrate epitope: a template for HIV vaccine design.

scientific article

Antibody responses to envelope glycoproteins in HIV-1 infection

scientific article

Antibody vs. HIV in a clash of evolutionary titans

scientific article

Antibody-mediated neutralization of Ebola virus can occur by two distinct mechanisms

scientific article

Antibody-mediated protection against SHIV challenge includes systemic clearance of distal virus

scientific article published on 18 August 2016

Antigenic and immunogenic study of membrane-proximal external region-grafted gp120 antigens by a DNA prime-protein boost immunization strategy

scientific article published on 31 January 2007

Antigenic mimicry of the HIV envelope by AIDS-associated pathogens.

scientific article published in October 2008

Aromatic residues at the edge of the antibody combining site facilitate viral glycoprotein recognition through membrane interactions

scientific article

As antibody findings mount, what comes next? Interview by Kristen Jill Kresge and Regina McEnery

scientific article published on January 1, 2011

Assorted mutations in the envelope gene of simian immunodeficiency virus lead to loss of neutralization resistance against antibodies representing a broad spectrum of specificities

scientific article

Author Correction: A Engineered immunogen binding to alum adjuvant enhances humoral immunity

scientific article published on 01 May 2020

Author Correction: Vaccine elicitation of HIV broadly neutralizing antibodies from engineered B cells

scientific article published on 07 December 2020

Autologous Antibody Responses to an HIV Envelope Glycan Hole Are Not Easily Broadened in Rabbits

scientific article published on 17 March 2020

B cells from knock-in mice expressing broadly neutralizing HIV antibody b12 carry an innocuous B cell receptor responsive to HIV vaccine candidates

scientific article published on 12 August 2013

Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target

scientific article (publication date: 9 October 2009)

Broad neutralization coverage of HIV by multiple highly potent antibodies

scientific article (publication date: 22 September 2011)

Broad neutralization of SARS-related viruses by human monoclonal antibodies

scientific article published on 15 June 2020

Broad sarbecovirus neutralizing antibodies define a key site of vulnerability on the SARS-CoV-2 spike protein

scientific article published on 16 May 2020

Broadly Neutralizing Antibodies Present New Prospects to Counter Highly Antigenically Diverse Viruses ⬇️

scientific article published on July 13, 2012

Broadly Neutralizing Antibodies to HIV and Their Role in Vaccine Design

scientific article published on May 2016

Broadly Neutralizing Antibody PGT121 Allosterically Modulates CD4 Binding via Recognition of the HIV-1 gp120 V3 Base and Multiple Surrounding Glycans

scientific article

Broadly cross-reactive HIV-1-neutralizing human monoclonal Fab selected for binding to gp120-CD4-CCR5 complexes

scientific article

Broadly neutralizing HIV antibodies define a glycan-dependent epitope on the prefusion conformation of gp41 on cleaved envelope trimers

scientific article published on 24 April 2014

Broadly neutralizing anti-HIV antibody 4E10 recognizes a helical conformation of a highly conserved fusion-associated motif in gp41

scientific article (publication date: February 2005)

Broadly neutralizing antibodies abrogate established hepatitis C virus infection

scientific article

Broadly neutralizing antibodies protect against hepatitis C virus quasispecies challenge

scientific article published on 6 December 2007

Broadly neutralizing antibodies targeting the HIV-1 envelope V2 apex confer protection against a clade C SHIV challenge

scientific article published on September 2017

Broadly neutralizing human anti-HIV antibody 2G12 is effective in protection against mucosal SHIV challenge even at low serum neutralizing titers

scientific article

Broadly neutralizing monoclonal antibodies 2F5 and 4E10 directed against the human immunodeficiency virus type 1 gp41 membrane-proximal external region protect against mucosal challenge by simian-human immunodeficiency virus SHIVBa-L

scientific article

Carbohydrate vaccines: developing sweet solutions to sticky situations?

scientific article published on April 2010

Cellular immunity elicited by human immunodeficiency virus type 1/ simian immunodeficiency virus DNA vaccination does not augment the sterile protection afforded by passive infusion of neutralizing antibodies

scientific article published on October 2003

Characterization of human immunodeficiency virus type 1 (HIV-1) Gag- and Gag peptide-specific CD4(+) T-cell clones from an HIV-1-seronegative donor following in vitro immunization

scientific article

Chemically Programmed Antibodies AS HIV-1 Attachment Inhibitors

scientific article published on May 2013

Clonify: unseeded antibody lineage assignment from next-generation sequencing data

scientific article

Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller

scientific article

Commonality despite exceptional diversity in the baseline human antibody repertoire

scientific article published on 21 January 2019

Comparing antigenicity and immunogenicity of engineered gp120.

scientific article

Comparison of Antibody-Dependent Cell-Mediated Cytotoxicity and Virus Neutralization by HIV-1 Env-Specific Monoclonal Antibodies.

scientific article published on 27 April 2016

Comparisons of the antibody repertoires of a humanized rodent and humans by high throughput sequencing

scientific article published on 24 January 2020

Complement is activated by IgG hexamers assembled at the cell surface

scientific article

Complete replication of hepatitis C virus in cell culture

scientific article (publication date: 22 July 2005)

Comprehensive antigenic map of a cleaved soluble HIV-1 envelope trimer

scientific article

Comprehensive cross-clade neutralization analysis of a panel of anti-human immunodeficiency virus type 1 monoclonal antibodies

scientific article

Computational prediction of broadly neutralizing HIV-1 antibody epitopes from neutralization activity data

scientific article (publication date: 2013)

Conformation of PrP(C) on the cell surface as probed by antibodies

scientific article published in February 2003

Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions

scientific article

Contrasting IgG Structures Reveal Extreme Asymmetry and Flexibility

scientific article published on 01 May 2002

Correction for Doores et al., Two Classes of Broadly Neutralizing Antibodies within a Single Lineage Directed to the High-Mannose Patch of HIV Envelope

scientific article published on June 2015

Correction for Khan et al., "Targeting the HIV-1 Spike and Coreceptor with Bi- and Trispecific Antibodies for Single-Component Broad Inhibition of Entry".

scientific article published on 15 May 2019

Correction: Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design

scientific article published on 14 September 2016

Correction: Novel in vitro booster vaccination to rapidly generate antigen-specific human monoclonal antibodies

scientific article published on 21 August 2017

Correction: Recombinant HIV Envelope Proteins Fail to Engage Germline Versions of Anti-CD4bs bNAbs.

scientific article published on 5 July 2013

Correction: The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies.

scientific article published on 30 December 2013

Correction: The Neonatal Fc Receptor (FcRn) Enhances Human Immunodeficiency Virus Type 1 (HIV-1) Transcytosis across Epithelial Cells.

scientific article

Corrigendum to “A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples”

scholarly article published in Journal of Immunological Methods

Corrigendum to: Infection of monkeys by simian-human immunodeficiency viruses with transmitted/founder clade C HIV-1 envelopes [Virology 475 (2015) 37–45]

article

Covalent display of oligosaccharide arrays in microtiter plates

scientific article published in July 2004

Cross-reactive serum and memory B cell responses to spike protein in SARS-CoV-2 and endemic coronavirus infection

scientific article published on 23 September 2020

Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer

scientific article

Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer

scientific article

Crystal structure of an intact human IgG: antibody asymmetry, flexibility, and a guide for HIV-1 vaccine design.

scientific article published on January 2003

Crystal structure of the broadly cross-reactive HIV-1-neutralizing Fab X5 and fine mapping of its epitope

scientific article

Cytosolic prion protein in neurons.

scientific article published in August 2003

Defining criteria for oligomannose immunogens for HIV using icosahedral virus capsid scaffolds

scientific article

Dengue Virus Evades AAV-Mediated Neutralizing Antibody Prophylaxis in Rhesus Monkeys

scientific article published on 24 July 2017

Design clues from functional constraints and broadly neutralizing antibodies

Design, synthesis, and biological evaluation of a biyouyanagin compound library

scientific article

Detection of antibodies against the four subtypes of ebola virus in sera from any species using a novel antibody-phage indicator assay.

scientific article

Determinants flanking the CD4 binding loop modulate macrophage tropism of human immunodeficiency virus type 1 R5 envelopes

scientific article

Developing an HIV vaccine

scientific article published on 16 March 2017

Differences in the Binding Affinity of an HIV-1 V2 Apex-Specific Antibody for the SIVsmm/mac Envelope Glycoprotein Uncouple Antibody-Dependent Cellular Cytotoxicity from Neutralization

scientific article published on 02 July 2019

Differential Antibody Responses to Conserved HIV-1 Neutralizing Epitopes in the Context of Multivalent Scaffolds and Native-Like gp140 Trimers

scientific article published on 28 February 2017

Differential binding of neutralizing and non-neutralizing antibodies to native-like soluble HIV-1 Env trimers, uncleaved Env proteins, and monomeric subunits

scientific article

Differential processing of HIV envelope glycans on the virus and soluble recombinant trimer

scientific article published in Nature Communications

Difficulties in eliciting broadly neutralizing anti-HIV antibodies are not explained by cardiolipin autoreactivity

scientific article published in October 2007

Direct Probing of Germinal Center Responses Reveals Immunological Features and Bottlenecks for Neutralizing Antibody Responses to HIV Env Trimer

scientific article

Directed evolution of an anti-prion protein scFv fragment to an affinity of 1 pM and its structural interpretation

scientific article

Dissecting the neutralizing antibody specificities of broadly neutralizing sera from human immunodeficiency virus type 1-infected donors

scientific article published on 4 April 2007

Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12.

scientific article

Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch

scientific article published on May 2016

Ebola virion attachment and entry into human macrophages profoundly effects early cellular gene expression

scientific article

Effective, low-titer antibody protection against low-dose repeated mucosal SHIV challenge in macaques

scientific article

Electron-Microscopy-Based Epitope Mapping Defines Specificities of Polyclonal Antibodies Elicited during HIV-1 BG505 Envelope Trimer Immunization

article

Elicitation of Neutralizing Antibodies Targeting the V2 Apex of the HIV Envelope Trimer in a Wild-Type Animal Model

scientific article published on October 2017

Elicitation of Neutralizing Antibodies Targeting the V2 Apex of the HIV Envelope Trimer in a Wild-Type Animal Model.

scientific article published on 28 January 2018

Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches

scientific article

Engineered immunogen binding to alum adjuvant enhances humoral immunity

scientific article published on 17 February 2020

Enhanced exposure of the CD4-binding site to neutralizing antibodies by structural design of a membrane-anchored human immunodeficiency virus type 1 gp120 domain

scientific article published on 04 March 2009

Enhancing the proteolytic maturation of human immunodeficiency virus type 1 envelope glycoproteins

scientific article

Envelope glycans of immunodeficiency virions are almost entirely oligomannose antigens.

scientific article

Fc receptor but not complement binding is important in antibody protection against HIV.

scientific article published in September 2007

Fetal demise and failed antibody therapy during Zika virus infection of pregnant macaques.

scientific article published on 24 April 2018

Fine epitope signature of antibody neutralization breadth at the HIV-1 envelope CD4-binding site

scientific article published on 8 March 2018

Fine mapping of the interaction of neutralizing and nonneutralizing monoclonal antibodies with the CD4 binding site of human immunodeficiency virus type 1 gp120.

scientific article

Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing

scientific article

Focused dampening of antibody response to the immunodominant variable loops by engineered soluble gp140.

scientific article published on February 2008

Functional stability of unliganded envelope glycoprotein spikes among isolates of human immunodeficiency virus type 1 (HIV-1)

scientific article (publication date: 2011)

Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody

scientific article

GP120: target for neutralizing HIV-1 antibodies

scientific article

Global site-specific N-glycosylation analysis of HIV envelope glycoprotein.

scientific article published on 28 March 2017

Global site-specific analysis of glycoprotein N-glycan processing.

scientific article published on 3 May 2018

Glycans Function as Anchors for Antibodies and Help Drive HIV Broadly Neutralizing Antibody Development

scientific article published on 8 September 2017

Glycans Function as Anchors for Antibodies and Help Drive HIV Broadly Neutralizing Antibody Development

scientific article published in November 2017

Glycosylation: Disease Targets and Therapy

scientific article published on 01 January 2005

HIV Broadly Neutralizing Antibodies: Taking Good Care Of The 98.

scientific article published in November 2016

HIV Envelope Glycoform Heterogeneity and Localized Diversity Govern the Initiation and Maturation of a V2 Apex Broadly Neutralizing Antibody Lineage

scientific article published in November 2017

HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies

scientific article published on 07 September 2016

HIV envelope trimer-elicited autologous neutralizing antibodies bind a region overlapping the N332 glycan supersite

scientific article published on 05 June 2020

HIV vaccine design and the neutralizing antibody problem

scientific article published in March 2004

HIV vaccine design: insights from live attenuated SIV vaccines

scientific article

HIV vaccine research: the way forward

scientific article published on 01 July 2008

HIV-1 VACCINES. HIV-1 neutralizing antibodies induced by native-like envelope trimers

scientific article

HIV-1 VACCINES. Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen.

scientific article

HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen

scientific article

HIV-1 escapes from N332-directed antibody neutralization in an elite neutralizer by envelope glycoprotein elongation and introduction of unusual disulfide bonds

scientific article published on 07 July 2016

HIV-1 neutralization: mechanisms and relevance to vaccine design

scientific article

HIV-1 vaccine design through minimizing envelope metastability

article

HIV: Immune memory downloaded

scientific article published in April 2009

Haplotype-Phased Synthetic Long Reads from Short-Read Sequencing

scientific article published on 20 January 2016

Harnessing Activin A Adjuvanticity to Promote Antibody Responses to BG505 HIV Envelope Trimers

scientific article published on 16 June 2020

Hepatitis C Virus E2 Envelope Glycoprotein Core Structure

scientific article

Heterogeneity of envelope molecules expressed on primary human immunodeficiency virus type 1 particles as probed by the binding of neutralizing and nonneutralizing antibodies

scientific article

Hidden Lineage Complexity of Glycan-Dependent HIV-1 Broadly Neutralizing Antibodies Uncovered by Digital Panning and Native-Like gp140 Trimer

scientific article published on 24 August 2017

Highly Attenuated Infection With a Vpr-Deleted Molecular Clone of Human Immunodeficiency Virus-1

scholarly article by Ayub Ali et al published 22 September 2018 in Journal of Infectious Diseases

Highly potent HIV-specific antibody neutralization in vitro translates into effective protection against mucosal SHIV challenge in vivo ⬇️

scientific article published on October 25, 2012

Holes in the Glycan Shield of the Native HIV Envelope Are a Target of Trimer-Elicited Neutralizing Antibodies

scientific article published on 17 August 2016

Human broadly neutralizing antibodies to the envelope glycoprotein complex of hepatitis C virus

scientific article

Human immunodeficiency virus type 1 elite neutralizers: individuals with broad and potent neutralizing activity identified by using a high-throughput neutralization assay together with an analytical selection algorithm

scientific article published on 13 May 2009

Human recombinant antimannan immunoglobulin G1 antibody confers resistance to hematogenously disseminated candidiasis in mice

scientific article

Hyperglycosylated Mutants of Human Immunodeficiency Virus (HIV) Type 1 Monomeric gp120 as Novel Antigens for HIV Vaccine Design ⬇️

scientific article published on May 1, 2003

IDEPI: rapid prediction of HIV-1 antibody epitopes and other phenotypic features from sequence data using a flexible machine learning platform

scientific article (publication date: September 2014)

Identification and characterization of a new cross-reactive human immunodeficiency virus type 1-neutralizing human monoclonal antibody

scientific article published in September 2004

Identification and specificity of broadly neutralizing antibodies against HIV

scientific article published on January 2017

Identification of Common Features in Prototype Broadly Neutralizing Antibodies to HIV Envelope V2 Apex to Facilitate Vaccine Design

scientific article published on November 2015

Identification of an HIV-1 Clade A Envelope That Exhibits Broad Antigenicity and Neutralization Sensitivity and Elicits Antibodies Targeting Three Distinct Epitopes ⬇️

scientific article published on March 6, 2013

Identification of peptides from human pathogens able to cross-activate an HIV-1-gag-specific CD4+ T cell clone

scientific article published in January 2006

Immune responses and HIV: a little order from the chaos

scientific article

Immune tolerance negatively regulates B cells in knock-in mice expressing broadly neutralizing HIV antibody 4E10

scientific article published on 12 August 2013

Immunochemical engineering of cell surfaces to generate virus resistance

scientific article published on 10 April 2017

Immunofocusing: antigen engineering to promote the induction of HIV-neutralizing antibodies ⬇️

scientific article published on November 1, 2003

Immunology. Square-dancing antibodies

scientific article published on 01 September 2007

Immunology. Sugar determines antibody activity

scientific article published on August 2006

Immunology. Two-in-one designer antibodies

scientific article published in March 2009

Incomplete Neutralization and Deviation from Sigmoidal Neutralization Curves for HIV Broadly Neutralizing Monoclonal Antibodies

scientific article published on 12 August 2015

Induction of Transient Virus Replication Facilitates Antigen-Independent Isolation of SIV-Specific Monoclonal Antibodies

scientific article published on 13 February 2020

Infection of monkeys by simian-human immunodeficiency viruses with transmitted/founder clade C HIV-1 envelopes

scientific article published on 22 November 2014

Inhibition of HIV Env binding to cellular receptors by monoclonal antibody 2G12 as probed by Fc-tagged gp120

article

Inhibition of HIV Env binding to cellular receptors by monoclonal antibody 2G12 as probed by Fc-tagged gp120.

scientific article

Inhibition of HIV-1 infectivity and epithelial cell transfer by human monoclonal IgG and IgA antibodies carrying the b12 V region

scientific article

Inhibition of mammalian glycan biosynthesis produces non-self antigens for a broadly neutralising, HIV-1 specific antibody

scientific article published on 16 June 2007

Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model

scientific article published on 15 June 2020

Isolation of potent neutralizing antibodies from a survivor of the 2014 Ebola virus outbreak

scientific article published on 18 February 2016

Limited or no protection by weakly or nonneutralizing antibodies against vaginal SHIV challenge of macaques compared with a strongly neutralizing antibody ⬇️

scientific article published on June 20, 2011

Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design.

scientific article

Live simian immunodeficiency virus vaccine correlate of protection: local antibody production and concentration on the path of virus entry

scientific article

Macaque long-term nonprogressors resist superinfection with multiple CD8+ T cell escape variants of simian immunodeficiency virus

scientific article

Macaques vaccinated with live-attenuated SIV control replication of heterologous virus

scientific article published on 06 October 2008

Macaques vaccinated with simian immunodeficiency virus SIVmac239Delta nef delay acquisition and control replication after repeated low-dose heterologous SIV challenge

scientific article

Major histocompatibility complex class I alleles associated with slow simian immunodeficiency virus disease progression bind epitopes recognized by dominant acute-phase cytotoxic-T-lymphocyte responses

scientific article published on August 2003

Making autoantibodies safe

scholarly article

Manipulating the selection forces during affinity maturation to generate cross-reactive HIV antibodies

scientific article published on 5 February 2015

Mapping Neutralizing Antibody Epitope Specificities to an HIV Env Trimer in Immunized and in Infected Rhesus Macaques

scientific article published on 01 September 2020

Mapping Polyclonal Antibody Responses in Non-human Primates Vaccinated with HIV Env Trimer Subunit Vaccines

scientific article published on 01 March 2020

Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates

scientific article published on 31 August 2020

Measuring prions causing bovine spongiform encephalopathy or chronic wasting disease by immunoassays and transgenic mice

scientific article

Mechanism of Neutralization by the Broadly Neutralizing HIV-1 Monoclonal Antibody VRC01 ⬇️

scientific article published on June 29, 2011

Mechanisms of escape from the PGT128 family of anti-HIV broadly neutralizing antibodies

scientific article published on 2 February 2016

Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design.

scientific article

Mining the antibodyome for HIV-1-neutralizing antibodies with next-generation sequencing and phylogenetic pairing of heavy/light chains

scientific article published on 27 March 2013

Mode of action for linear peptide inhibitors of HIV-1 gp120 interactions

scientific article

Modular synthesis of N-glycans and arrays for the hetero-ligand binding analysis of HIV antibodies

scientific article published on 7 March 2016

Molecular features of the broadly neutralizing immunoglobulin G1 b12 required for recognition of human immunodeficiency virus type 1 gp120.

scientific article

Motif-grafted antibodies containing the replicative interface of cellular PrP are specific for PrPSc

scholarly article

Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies

scientific article

Multiple roles for HIV broadly neutralizing antibodies

scientific article published on 01 October 2019

Multiplex PCR method for MinION and Illumina sequencing of Zika and other virus genomes directly from clinical samples

scientific article (publication date: 9 January 2017)

Multiplex PCR method for MinION and Illumina sequencing of Zika and other virus genomes directly from clinical samples.

scientific article

Murine Antibody Responses to Cleaved Soluble HIV-1 Envelope Trimers Are Highly Restricted in Specificity

scientific article

N-Butyldeoxynojirimycin is a broadly effective anti-HIV therapy significantly enhanced by targeted liposome delivery

scientific article published in October 2008

N332-Directed broadly neutralizing antibodies use diverse modes of HIV-1 recognition: inferences from heavy-light chain complementation of function

scientific article

Natural resistance of human immunodeficiency virus type 1 to the CD4bs antibody b12 conferred by a glycan and an arginine residue close to the CD4 binding loop

scientific article published on 02 April 2008

Nature of nonfunctional envelope proteins on the surface of human immunodeficiency virus type 1.

scientific article

Neutralization properties of simian immunodeficiency viruses infecting chimpanzees and gorillas

scientific article published on 21 April 2015

Neutralizing activity of antibodies to the V3 loop region of HIV-1 gp120 relative to their epitope fine specificity

scientific article published on 26 September 2008

Neutralizing antibodies generated during natural HIV-1 infection: good news for an HIV-1 vaccine?

scientific article published on August 2009

Neutralizing antibody affords comparable protection against vaginal and rectal simian/human immunodeficiency virus challenge in macaques.

scientific article published on June 2016

Neutralizing antibody fails to impact the course of Ebola virus infection in monkeys

scientific article

Neutralizing epitopes in the membrane-proximal external region of HIV-1 gp41 are influenced by the transmembrane domain and the plasma membrane

scientific article published on 11 January 2012

Neutralizing human Fab fragments against measles virus recovered by phage display

scientific article

Neutralizing human monoclonal antibodies prevent Zika virus infection in macaques.

scientific article published on October 2017

Nonhuman primate models and the failure of the Merck HIV-1 vaccine in humans

scientific article published on June 2008

Nonneutralizing antibodies to the CD4-binding site on the gp120 subunit of human immunodeficiency virus type 1 do not interfere with the activity of a neutralizing antibody against the same site

scientific article

Novel in vitro booster vaccination to rapidly generate antigen-specific human monoclonal antibodies

scientific article

Optimal Combinations of Broadly Neutralizing Antibodies for Prevention and Treatment of HIV-1 Clade C Infection

scientific article

Optimization of peptide arrays for studying antibodies to hepatitis C virus continuous epitopes

scientific article

PGV04, an HIV-1 gp120 CD4 binding site antibody, is broad and potent in neutralization but does not induce conformational changes characteristic of CD4.

scientific article published on 15 February 2012

Passive immunotherapy of viral infections: 'super-antibodies' enter the fray

scientific article published on 30 January 2018

Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques

scientific article

Potent Inhibition of HIV‐1 Entry with a Chemically Programmed Antibody Aided by an Efficient Organocatalytic Synthesis ⬇️

scientific article published on October 18, 2010

Potent Plasmablast-Derived Antibodies Elicited by the National Institutes of Health Dengue Vaccine

scientific article published on 6 September 2017

Potential of conventional & bispecific broadly neutralizing antibodies for prevention of HIV-1 subtype A, C & D infections.

scientific article published on 5 March 2018

Pre- and postexposure prophylaxis of Ebola virus infection in an animal model by passive transfer of a neutralizing human antibody

scientific article published on June 2002

Preparation and activities of macromolecule conjugates of the CCR5 antagonist Maraviroc

scientific article published on February 2014

Presenting native-like trimeric HIV-1 antigens with self-assembling nanoparticles

scientific article published on 28 June 2016

Prevention of hepatitis C virus infection using a broad cross-neutralizing monoclonal antibody (AR4A) and epigallocatechin gallate

scientific article published on 21 September 2015

Prevention of virus transmission to macaque monkeys by a vaginally applied monoclonal antibody to HIV-1 gp120.

scientific article published on 10 February 2003

Priming HIV-1 broadly neutralizing antibody precursors in human Ig loci transgenic mice

scientific article published on 8 September 2016

Printed covalent glycan array for ligand profiling of diverse glycan binding proteins

scientific article

Proceedings of the Frontiers of Retrovirology Conference 2016.

scientific article published on 26 September 2016

Promiscuous glycan site recognition by antibodies to the high-mannose patch of gp120 broadens neutralization of HIV.

scientific article published on May 2014

Protection against High-Dose Highly Pathogenic Mucosal SIV Challenge at Very Low Serum Neutralizing Titers of the Antibody-Like Molecule CD4-IgG2 ⬇️

scientific article published on July 27, 2012

Protection against a mixed SHIV challenge by a broadly neutralizing antibody cocktail.

scientific article published on September 2017

Protection of Humanized Mice From Repeated Intravaginal HIV Challenge by Passive Immunization: A Model for Studying the Efficacy of Neutralizing Antibodies In Vivo

scientific article published on 29 June 2016

Protective Efficacy of Broadly Neutralizing Antibodies with Incomplete Neutralization Activity against Simian-Human Immunodeficiency Virus in Rhesus Monkeys

scientific article

Protein and Glycan Mimicry in HIV Vaccine Design.

scientific article published on 24 April 2019

Public health. A sound rationale needed for phase III HIV-1 vaccine trials

scientific article

Publisher Correction: Recent progress in broadly neutralizing antibodies to HIV

scientific article published on 01 March 2019

Quantitation of DNA and RNA

scientific article published on 01 November 2007

Rapid Germinal Center and Antibody Responses in Non-human Primates after a Single Nanoparticle Vaccine Immunization ⬇️

scientific article published on 01 November 2019

Rapid and Focused Maturation of a VRC01-Class HIV Broadly Neutralizing Antibody Lineage Involves Both Binding and Accommodation of the N276-Glycan

scientific article published on 01 July 2019

Rapid development of glycan-specific, broad, and potent anti–HIV-1 gp120 neutralizing antibodies in an R5 SIV/HIV chimeric virus infected macaque ⬇️

scientific article published on November 28, 2011

Rapid elicitation of broadly neutralizing antibodies to HIV by immunization in cows

scientific article published on 20 July 2017

Rapid isolation of potent SARS-CoV-2 neutralizing antibodies and protection in a small animal model

scientific article published on 12 May 2020

Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors

scientific article

Rational Vaccine Design in the Time of COVID-19

scientific article published on 01 May 2020

Rational antibody-based HIV-1 vaccine design: current approaches and future directions

scientific article

Reactivity-based one-pot synthesis of oligomannoses: defining antigens recognized by 2G12, a broadly neutralizing anti-HIV-1 antibody

scientific article published on February 2004

Recent progress in broadly neutralizing antibodies to HIV

article

Recombinant HIV envelope proteins fail to engage germline versions of anti-CD4bs bNAbs

scientific article

Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex

scientific article

Rectal Acquisition of SIVmac239 Infection Despite Vaccine-Induced Immune Responses Against the Entire SIV Proteome

scientific article published on 07 October 2020

Redox-Triggered Infection by Disulfide-Shackled Human Immunodeficiency Virus Type 1 Pseudovirions ⬇️

scientific article published on May 1, 2003

Reproducing SIVΔnef vaccine correlates of protection: trimeric gp41 antibody concentrated at mucosal front lines

scientific article

Reprogramming the antigen specificity of B cells using genome-editing technologies

scientific article published on 17 January 2019

Rhesus Macaques Vaccinated with , , and Manifest Early Control of SIVmac239 Replication

scholarly article by Mauricio A Martins et al published 15 August 2018 in Journal of Virology

Robust hepatitis C virus infection in vitro

scientific article

Role of Ebola virus secreted glycoproteins and virus-like particles in activation of human macrophages

scientific article

Scaffolding to build a rational vaccine design strategy ⬇️

scientific article published on October 11, 2010

Selection of unadapted, pathogenic SHIVs encoding newly transmitted HIV-1 envelope proteins

scientific article

Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding

scientific article

Sequential Immunization Elicits Broadly Neutralizing Anti-HIV-1 Antibodies in Ig Knockin Mice

scientific article published on September 2016

Simian immunodeficiency virus engrafted with human immunodeficiency virus type 1 (HIV-1)-specific epitopes: replication, neutralization, and survey of HIV-1-positive plasma

scientific article published on March 2006

Simplifying the synthesis of SIgA: combination of dIgA and rhSC using affinity chromatography

scientific article published on 25 June 2013

Slow Delivery Immunization Enhances HIV Neutralizing Antibody and Germinal Center Responses via Modulation of Immunodominance

scientific article published on 09 May 2019

Slow Delivery Immunization Enhances HIV Neutralizing Antibody and Germinal Center Responses via Modulation of Immunodominance

scientific article published on 01 January 2020

SnapShot: broadly neutralizing antibodies

scientific article

Somatic Populations of PGT135-137 HIV-1-Neutralizing Antibodies Identified by 454 Pyrosequencing and Bioinformatics

scientific article

Strategies for a multi-stage neutralizing antibody-based HIV vaccine

article

Structural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120

scientific article

Structural Basis of Zika Virus Specific Neutralization in Subsequent Flavivirus Infections

scientific article published on 24 November 2020

Structural Constraints Determine the Glycosylation of HIV-1 Envelope Trimers

scientific article published on 16 June 2015

Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors

scientific article

Structural basis for diverse N-glycan recognition by HIV-1–neutralizing V1–V2–directed antibody PG16

scientific article

Structural basis of a public antibody response to SARS-CoV-2

scientific article published on 09 June 2020

Structural basis of a shared antibody response to SARS-CoV-2

scientific article

Structural basis of broad HIV neutralization by a vaccine-induced cow antibody

scientific article published on 27 May 2020

Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV-1 antibody 4E10.

scientific article published on 10 November 2006

Structural basis of hepatitis C virus neutralization by broadly neutralizing antibody HCV1 ⬇️

scientific article published on May 23, 2012

Structural definition of a conserved neutralization epitope on HIV-1 gp120

scientific article

Structural definition of a pan-sarbecovirus neutralizing epitope on the spike S2 subunit

scientific article published on 11 April 2022

Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers

scientific article

Structural evolution of glycan recognition by a family of potent HIV antibodies

scientific article

Structure and Recognition of a Novel HIV-1 gp120-gp41 Interface Antibody that Caused MPER Exposure through Viral Escape.

scientific article

Structure and function of broadly reactive antibody PG16 reveal an H3 subdomain that mediates potent neutralization of HIV-1

scientific article

Structure of 2G12 Fab2 in complex with soluble and fully glycosylated HIV-1 Env by negative-stain single-particle electron microscopy

scientific article

Structure of Antibody F425-B4e8 in Complex with a V3 Peptide Reveals a New Binding Mode for HIV-1 Neutralization

scientific article

Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

scientific article

Structure of a high-affinity "mimotope" peptide bound to HIV-1-neutralizing antibody b12 explains its inability to elicit gp120 cross-reactive antibodies

scientific article

Structure of the Ebola virus glycoprotein bound to an antibody from a human survivor

scientific article

Structure-based design of native-like HIV-1 envelope trimers to silence non-neutralizing epitopes and eliminate CD4 binding.

scientific article published on 21 November 2017

Structure-function analysis of the epitope for 4E10, a broadly neutralizing human immunodeficiency virus type 1 antibody

scientific article

Structure-function in HIV research. Interview by Simon Noble

scientific article

Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120

scientific article

Swift antibodies to counter emerging viruses

scientific article

Synthesis and biological evaluation of 2',4'- and 3',4'-bridged nucleoside analogues.

scientific article

Synthetic development of a broadly neutralizing antibody against snake venom long-chain α-neurotoxins

scientific article published in 2024

Synthetic glycopeptides reveal the glycan specificity of HIV-neutralizing antibodies.

scientific article published on 30 June 2013

Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection

Systems Biology Methods Applied to Blood and Tissue for a Comprehensive Analysis of Immune Response to Hepatitis B Vaccine in Adults

scientific article published on 04 November 2020

Tailored Immunogens Direct Affinity Maturation toward HIV Neutralizing Antibodies

scientific article published on September 2016

Taking down defenses to improve vaccines

scientific article

Targeting the HIV-1 Spike and Coreceptor with Bi- and Trispecific Antibodies for Single-Component Broad Inhibition of Entry

scholarly article by Salar N Khan et al published 15 September 2018 in Journal of Virology

Targeting the carbohydrates on HIV-1: Interaction of oligomannose dendrons with human monoclonal antibody 2G12 and DC-SIGN

scientific article

Techniques and tactics used in determining the structure of the trimericebolavirusglycoprotein

scientific article

Tetherin antagonism by Vpu protects HIV-infected cells from antibody-dependent cell-mediated cytotoxicity.

scientific article

The Chimpanzee SIV Envelope Trimer: Structure and Deployment as an HIV Vaccine Template

article

The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies

scientific article

The INNs and outs of antibody nonproprietary names

scientific article published in January 2016

The Neonatal Fc receptor (FcRn) enhances human immunodeficiency virus type 1 (HIV-1) transcytosis across epithelial cells

scientific article

The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of alpha1-->2 mannose residues on the outer face of gp120.

scientific article

The carbohydrate epitope of the neutralizing anti-HIV-1 antibody 2G12.

scientific article

The challenges of eliciting neutralizing antibodies to HIV-1 and to influenza virus.

scientific article

The glycan shield of HIV is predominantly oligomannose independently of production system or viral clade.

scientific article

The human immunodeficiency virus type 1 envelope spike of primary viruses can suppress antibody access to variable regions

scientific article

The long third complementarity-determining region of the heavy chain is important in the activity of the broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2F5.

scientific article published on March 2004

Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys

scientific article

Therapeutic neutralizing monoclonal antibody administration protects against lethal yellow fever virus infection

scientific article published in 2023

Total synthesis, revised structure, and biological evaluation of biyouyanagin A and analogues thereof

scientific article published on 23 July 2008

Toward a Carbohydrate-Based HIV-1 Vaccine

article

Toward a more accurate view of human B-cell repertoire by next-generation sequencing, unbiased repertoire capture and single-molecule barcoding

scientific article published on 27 October 2014

Toward an AIDS vaccine

scientific article

Toward superhuman SARS-CoV-2 immunity?

scientific article published on 30 November 2020

Trafficking of prion proteins through a caveolae-mediated endosomal pathway

scientific article

Transplanting supersites of HIV-1 vulnerability

scientific article

Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G

scientific article

Trispecific broadly neutralizing HIV antibodies mediate potent SHIV protection in macaques

scientific article

Two classes of broadly neutralizing antibodies within a single lineage directed to the high-mannose patch of HIV envelope

scientific article

Tyrosine sulfation of human antibodies contributes to recognition of the CCR5 binding region of HIV-1 gp120.

scientific article published in July 2003

Uncleaved prefusion-optimized gp140 trimers derived from analysis of HIV-1 envelope metastability.

scientific article published on 28 June 2016

Unprecedented Role of Hybrid N-Glycans as Ligands for HIV-1 Broadly Neutralizing Antibodies

scientific article published on 26 March 2018

Unusual features of vaccinia virus extracellular virion form neutralization resistance revealed in human antibody responses to the smallpox vaccine

scientific article published on 14 November 2012

Urgently needed: a filter for the HIV-1 vaccine pipeline

scientific article published on 01 August 2004

Vaccine elicitation of HIV broadly neutralizing antibodies from engineered B cells

scientific article published on 17 November 2020

Vaccine priming of rare HIV broadly neutralizing antibody precursors in nonhuman primates

scientific article published in 2024

Vaccine-Induced Protection from Homologous Tier 2 SHIV Challenge in Nonhuman Primates Depends on Serum-Neutralizing Antibody Titers

scholarly article by Matthias G Pauthner et al published 15 January 2019 in Immunity

Vaccine-induced cellular immune responses reduce plasma viral concentrations after repeated low-dose challenge with pathogenic simian immunodeficiency virus SIVmac239

scientific article

Vaccine-induced immune responses against both Gag and Env improve control of simian immunodeficiency virus replication in rectally challenged rhesus macaques.

scientific article

Variable loop glycan dependency of the broad and potent HIV-1-neutralizing antibodies PG9 and PG16.

scientific article

Variation in HIV-1 R5 macrophage-tropism correlates with sensitivity to reagents that block envelope: CD4 interactions but not with sensitivity to other entry inhibitors.

scientific article published on 18 January 2008

Very few substitutions in a germ line antibody are required to initiate significant domain exchange.

scientific article

Viral vaccines: past successes and future challenges

scientific article

What Are the Most Powerful Immunogen Design Vaccine Strategies? Reverse Vaccinology 2.0 Shows Great Promise

scientific article published on 3 February 2017

Zika virus activates de novo and cross-reactive memory B cell responses in dengue-experienced donors.

scientific article published on August 2017

bNAber: database of broadly neutralizing HIV antibodies

scientific article

gp41: HIV's shy protein

article

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