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List of works by Angela Kashuba

A Pharmacokinetic and Pharmacodynamic Study of Maraviroc as Acute Graft-versus-Host Disease Prophylaxis in Pediatric Allogeneic Stem Cell Transplant Recipients with Nonmalignant Diagnoses.

scientific article published on 3 August 2016

A Translational Pharmacology Approach to Predicting Outcomes of Preexposure Prophylaxis Against HIV in Men and Women Using Tenofovir Disoproxil Fumarate With or Without Emtricitabine

scientific article published on 24 February 2016

A multi-compartment single and multiple dose pharmacokinetic comparison of rectally applied tenofovir 1% gel and oral tenofovir disoproxil fumarate

scientific article

A multi-compartment, single and multiple dose pharmacokinetic study of the vaginal candidate microbicide 1% tenofovir gel

scientific article (publication date: 2011)

A novel LC-ESI-MS method for the simultaneous determination of etravirine, darunavir and ritonavir in human blood plasma

scientific article published on 09 June 2009

A simple and sensitive bioanalytical assay for simultaneous determination of omeprazole and its three major metabolites in human blood plasma using RP-HPLC after a simple liquid-liquid extraction procedure

scientific article published on 22 August 2006

A spatio-temporal assessment of simian/human immunodeficiency virus (SHIV) evolution reveals a highly dynamic process within the host.

scientific article

AIDS diarrhea and antiretroviral drug concentrations: a matched-pair cohort study in Port au Prince, Haiti

scientific article

Absence of Effect of Terbinafine on the Activity of CYP1A2, NAT‐2, and Xanthine Oxidase ⬇️

scientific article published on May 1, 1998

Absence of sustained hyperlactatemia in HIV-infected patients with risk factors for mitochondrial toxicity

scientific article published in March 2004

Accuracy of Self-Report and Pill-Count Measures of Adherence in the FEM-PrEP Clinical Trial: Implications for Future HIV-Prevention Trials

scientific article published on May 2015

Activities of cytochrome P450 1A2, N-acetyltransferase 2, xanthine oxidase, and cytochrome P450 2D6 are unaltered in children with cystic fibrosis

scientific article published in March 2004

Addition of 7 Days of Zidovudine Plus Lamivudine to Peripartum Single-Dose Nevirapine Effectively Reduces Nevirapine Resistance Postpartum in HIV-Infected Mothers in Malawi ⬇️

scientific article published on August 1, 2010

An accurate and precise high-performance liquid chromatography method for the rapid quantification of the novel HIV integrase inhibitor raltegravir in human blood plasma after solid phase extraction

scientific article published on 11 September 2008

An in-depth comparison of latent HIV-1 reactivation in multiple cell model systems and resting CD4+ T cells from aviremic patients

scientific article (publication date: 2013)

Analysis of Antiretrovirals in Single Hair Strands for Evaluation of Drug Adherence with Infrared-Matrix-Assisted Laser Desorption Electrospray Ionization Mass Spectrometry Imaging.

scientific article published on 21 December 2015

Antiretroviral Concentrations and Surrogate Measures of Efficacy in the Brain Tissue and CSF of Preclinical Species

article

Antiretroviral Drug Concentrations in Lymph Nodes: A Cross-Species Comparison of the Effect of Drug Transporter Expression, Viral Infection, and Sex in Humanized Mice, Nonhuman Primates, and Humans

scientific article published on 24 June 2019

Antiretroviral Penetration across Three Preclinical Animal Models and Humans in Eight Putative HIV Viral Reservoirs

scientific article published on 20 December 2019

Antiretroviral Pharmacology in Mucosal Tissues ⬇️

scientific article published on July 1, 2013

Antiretroviral Therapy Concentrations Differ in Gut vs. Lymph Node Tissues and Are Associated With HIV Viral Transcription by a Novel RT-ddPCR Assay

scientific article published on 01 April 2020

Antiretroviral drug concentrations and HIV RNA in the genital tract of HIV-infected women receiving long-term highly active antiretroviral therapy

scientific article published in March 2008

Antiretroviral drug exposure in the female genital tract: implications for oral pre- and post-exposure prophylaxis

scientific article

Antiretroviral penetration and drug transporter concentrations in the spleens of three preclinical animal models and humans

scientific article published on 13 July 2020

Antiretroviral pharmacokinetics in mothers and breastfeeding infants from 6 to 24 weeks post-partum: results of the BAN Study

scientific article

Antiretroviral therapy for prevention of HIV infection: new clues from an animal model

scientific article

Antiviral agents and HIV prevention: controversies, conflicts, and consensus

scientific article published on August 2012

Application of a Scavenger Receptor A1 Targeted Polymeric Prodrug Platform for Lymphatic Drug Delivery in HIV

scientific article published on 25 August 2020

Association between Use of Methadone, Other Central Nervous System Depressants, and QTc Interval-Prolonging Medications and Risk of Mortality in a Large Cohort of Women Living with or at Risk for Human Immunodeficiency Virus Infection

scientific article published on 13 August 2019

Authors' response: Poor correlation between 6β-hydroxycortisol:cortisol molar ratios and midazolam clearance as measure of hepatic CYP3A activity: a comment.

scientific article

Bottlenecks in HIV-1 transmission: insights from the study of founder viruses

scientific article

Brief Report: Significant Decreases in Both Total and Unbound Lopinavir and Amprenavir Exposures During Coadministration: ACTG Protocol A5143/A5147s Results

scientific article

CCR5 inhibitor as novel acute graft versus host disease prophylaxis in children and young adults undergoing allogeneic stem cell transplant: results of the phase II study

scientific article published on 09 April 2020

CYP2B6 variants and plasma efavirenz concentrations during antiretroviral therapy in Port-au-Prince, Haiti

scientific article

Can antiretroviral therapy be used to prevent sexual transmission of human immunodeficiency virus type 1?

scientific article

Cervicovaginal and Rectal Fluid as a Surrogate Marker of Antiretroviral Tissue Concentration: Implications for Clinical Trial Design

scientific article published on 18 March 2016

Challenges and Solutions for Future Pharmacy Practice in the Era of Precision Medicine

scientific article published on 01 August 2018

Cisapride: a potential model substrate to assess cytochrome P4503A4 activity in vivo

scientific article published on March 2003

Clinical Pharmacokinetics and Pharmacodynamics of Drugs in the Central Nervous System

scientific article published on 20 February 2018

Clinical pharmacokinetic, pharmacodynamic and drug-interaction profile of the integrase inhibitor dolutegravir

scientific article

Co-localized confocal Raman spectroscopy and optical coherence tomography (CRS-OCT) for depth-resolved analyte detection in tissue

scientific article published on 8 May 2015

Coadministration of lopinavir/ritonavir and phenytoin results in two-way drug interaction through cytochrome P-450 induction

scientific article published in August 2004

Combined oral contraceptives and antiretroviral PK/PD in Malawian women: pharmacokinetics and pharmacodynamics of a combined oral contraceptive and a generic combined formulation antiretroviral in Malawi

scientific article

Combined phenotypic assessment of cytochrome p450 1A2, 2C9, 2C19, 2D6, and 3A, N-acetyltransferase-2, and xanthine oxidase activities with the "Cooperstown 5+1 cocktail".

scientific article published in November 2003

Comparison of once-daily versus twice-daily combination antiretroviral therapy in treatment-naive patients: results of AIDS clinical trials group (ACTG) A5073, a 48-week randomized controlled trial

scientific article

Comparison of various urine collection intervals for caffeine and dextromethorphan phenotyping in children

scientific article

Contemporary Drug-Drug Interactions in HIV Treatment

scientific article published on 25 March 2019

Correction for Mavigner et al., "Simian Immunodeficiency Virus Persistence in Cellular and Anatomic Reservoirs in Antiretroviral Therapy-Suppressed Infant Rhesus Macaques"

Correction for Mavigner et al., "Simian Immunodeficiency Virus Persistence in Cellular and Anatomic Reservoirs in Antiretroviral Therapy-Suppressed Infant Rhesus Macaques"

scientific article published on 31 March 2020

Correlation between compartmental tenofovir concentrations and an ex vivo rectal biopsy model of tissue infectibility in the RMP-02/MTN-006 phase 1 study

scientific article

Critical need for appropriate mucosal sample collection to determine relational animal pharmacokinetic-pharmacodynamic models in HIV prevention

scientific article published on 30 August 2013

Cytokine regulation of P-glycoprotein

scientific article

Darunavir for Use in Pregnant Women with HIV.

scientific article published on 7 October 2017

Darunavir, ritonavir, and etravirine pharmacokinetics in the cervicovaginal fluid and blood plasma of HIV-infected women

scientific article

Decreased Tenofovir Diphosphate Concentrations in a Transgender Female Cohort: Implications for Human Immunodeficiency Virus Preexposure Prophylaxis

scientific article published on 01 November 2019

Development and validation of an LC-MS/MS assay for the quantification of dolutegravir extracted from human hair

article

Development of a composite measure of product adherence, protocol compliance, and semen exposure using DNA and protein biomarkers for topical HIV prevention studies

scientific article

Development of a highly efficient extraction technique and specific multiplex assay for measuring antiretroviral drug concentrations in breast milk

scientific article published on 01 August 2007

Development of a liquid chromatography-tandem mass spectrometry assay of six antimicrobials in plasma for pharmacokinetic studies in premature infants

scientific article published on 22 September 2011

Differences in Local and Systemic TFV PK Among Premenopausal Versus Postmenopausal Women Exposed to TFV 1% Vaginal Gel.

scientific article published on 7 February 2018

Differential extracellular and intracellular concentrations of zidovudine and lamivudine in semen and plasma of HIV-1-infected men.

scientific article

Differential extracellular, but similar intracellular, disposition of two tenofovir formulations in the male genital tract

scientific article published on 01 January 2019

Differential penetration of raltegravir throughout gastrointestinal tissue: implications for eradication and cure

scientific article

Dolutegravir pharmacokinetics in the genital tract and colorectum of HIV-negative men after single and multiple dosing

scientific article published on September 2013

Dose separation does not overcome the pharmacokinetic interaction between fosamprenavir and lopinavir/ritonavir

scientific article

Dosing of Aminoglycosides To Rapidly Attain Pharmacodynamic Goals and Hasten Therapeutic Response by Using Individualized Pharmacokinetic Monitoring of Patients with Pneumonia Caused by Gram-Negative Organisms ⬇️

scientific article published on July 1, 1998

Drug concentrations after topical and oral antiretroviral pre-exposure prophylaxis: implications for HIV prevention in women

scientific article published on July 2011

Drug interactions with new and investigational antiretrovirals

scientific article

Drug resistance and plasma viral RNA level after ineffective use of oral pre-exposure prophylaxis in women

scientific article published on January 2015

Drug-drug interactions and the pharmacotherapy of HIV infection.

scientific article

Dynamics of the decay of HIV RNA and distribution of bictegravir in the genital tract and rectum in antiretroviral-naïve HIV-1-infected adults treated with bictegravir/emtricitabine/tenofovir alafenamide (Spanish HIV/AIDS Research Network, PreEC/RIS

scientific article published on 18 September 2020

Effect of HIV infection and menopause status on raltegravir pharmacokinetics in the blood and genital tract

scientific article published on 03 June 2015

Effect of Hormonal Contraception on Pharmacokinetics of Vaginal Tenofovir in Healthy Women: Increased Tenofovir Diphosphate in Injectable Depot Medroxyprogesterone Acetate Users

scientific article published on 01 January 2019

Effect of a triphasic oral contraceptive on drug-metabolizing enzyme activity as measured by the validated Cooperstown 5+1 cocktail

scientific article

Effect of fluvoxamine therapy on the activities of CYP1A2, CYP2D6, and CYP3A as determined by phenotyping*

scientific article published on September 1, 1998

Effect of omeprazole on the plasma concentrations of indinavir when administered alone and in combination with ritonavir

scientific article published on March 2008

Effects of fluvastatin and cigarette smoking on CYP2C9 activity measured using the probe S-warfarin

scientific article published on 27 April 2006

Effects of formulation and dosing strategy on amprenavir concentrations in the seminal plasma of human immunodeficiency virus type 1-infected men.

scientific article published on 23 August 2002

Effects of the H2-receptor antagonist famotidine on the pharmacokinetics of atazanavir-ritonavir with or without tenofovir in HIV-infected patients

scientific article

Ending the evidence gap for pregnancy, HIV and co-infections: ethics guidance from the PHASES project

scientific article published in December 2021

Evaluating nurses' implementation of an infant-feeding counseling protocol for HIV-infected mothers: The Ban Study in Lilongwe, Malawi

scientific article

Evaluation of Digital Image Recognition Methods for Mass Spectrometry Imaging Data Analysis

scientific article published on 15 October 2018

Exploration of CYP450 and drug transporter genotypes and correlations with nevirapine exposure in Malawians

scientific article published on 23 November 2011

Expression of six drug transporters in vaginal, cervical, and colorectal tissues: Implications for drug disposition in HIV prevention

scientific article

FEM-PrEP: adherence patterns and factors associated with adherence to a daily oral study product for pre-exposure prophylaxis

scientific article

Food insecurity is associated with lower levels of antiretroviral drug concentrations in hair among a cohort of women living with HIV in the United States

scientific article published on 14 October 2019

Formulation, pharmacokinetics and pharmacodynamics of topical microbicides

scientific article

Fosamprenavir. Vertex Pharmaceuticals/GlaxoSmithKline

scientific article

Full validation of an analytical method for the HIV-protease inhibitor atazanavir in combination with 8 other antiretroviral agents and its applicability to therapeutic drug monitoring

scientific article published on 01 August 2006

Genital Tenofovir Concentrations Correlate With Protection Against HIV Infection in the CAPRISA 004 Trial: Importance of Adherence for Microbicide Effectiveness

scientific article published in July 2015

Genital tract, cord blood, and amniotic fluid exposures of seven antiretroviral drugs during and after pregnancy in human immunodeficiency virus type 1-infected women

scientific article published on 23 March 2009

HIV Persistence in Gut-Associated Lymphoid Tissues: Pharmacological Challenges and Opportunities

scientific article published on 28 February 2017

HIV antiretroviral postexposure prophylaxis: a cautionary note

scientific article published on 13 October 2005

HIV pre-exposure prophylaxis: mucosal tissue drug distribution of RT inhibitor Tenofovir and entry inhibitor Maraviroc in a humanized mouse model

scientific article published on 7 August 2014

HIV prevention by oral preexposure prophylaxis

scientific article published on March 2012

HIV-1 Tat and opioids act independently to limit antiretroviral brain concentrations and reduce blood-brain barrier integrity

scientific article published on 17 May 2019

HIV-1 treatment as prevention: the good, the bad, and the challenges

scientific article published on July 2011

HIV-1-RNA Decay and Dolutegravir Concentrations in Semen of Patients Starting a First Antiretroviral Regimen.

scientific article

Heterogeneous antiretroviral drug distribution and HIV/SHIV detection in the gut of three species

scientific article published on 01 July 2019

High-performance liquid chromatography assay for the determination of the HIV-protease inhibitor tipranavir in human plasma in combination with nine other antiretroviral medications

scientific article published on 22 January 2007

High-performance liquid chromatography assay for the quantification of HIV protease inhibitors and non-nucleoside reverse transcriptase inhibitors in human plasma

scientific article

Hormonal Contraceptives Differentially Suppress TFV and TAF Inhibition of HIV Infection and TFV-DP in Blood and Genital Tract CD4+ T cells

scientific article published on 18 December 2017

Human Immunodeficiency Virus Type 1 RNA Detected in the Central Nervous System (CNS) After Years of Suppressive Antiretroviral Therapy Can Originate from a Replicating CNS Reservoir or Clonally Expanded Cells

scientific article published on 01 September 2019

Identification of a cranberry juice product that inhibits enteric CYP3A-mediated first-pass metabolism in humans.

scientific article published on 29 December 2008

Immunologic, virologic, and pharmacologic characterization of the female upper genital tract in HIV-infected women

scientific article

Influence of hair treatments on detection of antiretrovirals by mass spectrometry imaging

scientific article published on 18 May 2020

Infrared Matrix-Assisted Laser Desorption Electrospray Ionization Mass Spectrometry Imaging of Human Hair to Characterize Longitudinal Profiles of the Antiretroviral Maraviroc for Adherence Monitoring

scientific article published on 06 August 2019

Interactions of the hepatitis C virus protease inhibitor faldaprevir with cytochrome P450 enzymes: in vitro and in vivo correlation

scientific article published on 14 January 2015

Interindividual variability in pharmacokinetics of generic nucleoside reverse transcriptase inhibitors in TB/HIV-coinfected ghanaian patients: UGT2B7*1c is associated with faster zidovudine clearance and glucuronidation

scientific article

Kaletra (lopinavir/ritonavir).

scientific article

Kupffer cell-mediated IL-2 suppression of CYP3A activity in human hepatocytes

scientific article (publication date: March 2004)

Lack of viral control and development of combination antiretroviral therapy escape mutations in macaques after bone marrow transplantation

scientific article

Limited sampling strategy of S-warfarin concentrations, but not warfarin S/R ratios, accurately predicts S-warfarin AUC during baseline and inhibition in CYP2C9 extensive metabolizers

scientific article

Limited sampling strategy to predict AUC of the CYP3A phenotyping probe midazolam in adults: application to various assay techniques

scientific article

Long-Acting Rilpivirine (RPV) Preexposure Prophylaxis Does Not Inhibit Vaginal Transmission of RPV-Resistant HIV-1 or Select for High-Frequency Drug Resistance in Humanized Mice

scientific article published on 31 March 2020

Lopinavir/ritonavir induces the hepatic activity of cytochrome P450 enzymes CYP2C9, CYP2C19, and CYP1A2 but inhibits the hepatic and intestinal activity of CYP3A as measured by a phenotyping drug cocktail in healthy volunteers

scientific article published in May 2006

Low Frequency of Drug-Resistant Variants Selected by Long-Acting Rilpivirine in Macaques Infected with Simian Immunodeficiency Virus Containing HIV-1 Reverse Transcriptase

scientific article

Mapping antiretroviral drugs in tissue by IR-MALDESI MSI coupled to the Q Exactive and comparison with LC-MS/MS SRM assay.

scientific article published on 18 April 2014

Maraviroc concentrates in the cervicovaginal fluid and vaginal tissue of HIV-negative women

scientific article published on August 2009

Mass Spectroscopy Imaging of Hair Strands Captures Short-Term and Long-Term Changes in Emtricitabine Adherence

scientific article published on 10 March 2022

Mass spectrometry imaging reveals heterogeneous efavirenz distribution within putative HIV reservoirs

scientific article

Maternal-fetal pharmacokinetics and dynamics of a single intrapartum dose of maraviroc in rhesus macaques

scientific article

Measuring adherence by visual inspection of returned empty gel applicators in the CAPRISA 004 microbicide trial

scientific article

Mechanisms of pharmacokinetic and pharmacodynamic drug interactions associated with ritonavir-enhanced tipranavir

scientific article

Models for predicting effective HIV chemoprevention in women

scientific article

Modest but variable effect of rifampin on steady-state plasma pharmacokinetics of efavirenz in healthy African-American and Caucasian volunteers

scientific article

Mucosal Tissue Explants as Surrogates for In Vivo Efficacy of Microbicides

scientific article published in October 2014

Mucosal tissue pharmacokinetics of the integrase inhibitor raltegravir in a humanized mouse model: Implications for HIV pre-exposure prophylaxis

scientific article

Multimodal analysis of drug transporter expression in gastrointestinal tissue

scientific article published on 05 June 2017

Narrative review: antiretroviral therapy to prevent the sexual transmission of HIV-1.

scientific article published on April 2007

Patient and clinician perspectives on optimizing graphical displays of longitudinal medication adherence data

scientific article published on 02 January 2019

Penetration of tenofovir and emtricitabine in mucosal tissues: implications for prevention of HIV-1 transmission

scientific article

Pharmacokinetic Modeling of Lamivudine and Zidovudine Triphosphates Predicts Differential Pharmacokinetics in Seminal Mononuclear Cells and Peripheral Blood Mononuclear Cells.

scientific article

Pharmacokinetic and pharmacodynamic investigation of efavirenz in the semen and blood of human immunodeficiency virus type 1-infected men.

scientific article published on 7 October 2002

Pharmacokinetic comparison of generic and trade formulations of lamivudine, stavudine and nevirapine in HIV-infected Malawian adults

article

Pharmacokinetic modelling of efavirenz, atazanavir, lamivudine and tenofovir in the female genital tract of HIV-infected pre-menopausal women

scientific article

Pharmacokinetics and Immunological Effects of Romidepsin in Rhesus Macaques

scientific article published on 11 December 2020

Pharmacokinetics and Pharmacodynamics in HIV Prevention; Current Status and Future Directions: A Summary of the DAIDS and BMGF Sponsored Think Tank on Pharmacokinetics (PK)/Pharmacodynamics (PD) in HIV Prevention ⬇️

scientific article published on May 22, 2013

Pharmacokinetics of antiretrovirals in genital secretions and anatomic sites of HIV transmission: implications for HIV prevention

scientific article

Pharmacokinetics of antiretrovirals in mucosal tissue

scientific article published on 22 March 2015

Pharmacokinetics of tenofovir following intravaginal and intrarectal administration of tenofovir gel to rhesus macaques

scientific article published on 10 October 2011

Pharmacology of HIV integrase inhibitors

scientific article published on September 2012

Physiological Changes During the Menstrual Cycle and Their Effects on the Pharmacokinetics and Pharmacodynamics of Drugs

scientific article published on March 1, 1998

Plasma and Intracellular Concentrations in HIV-Infected Patients Requiring Hemodialysis Dosed With Tenofovir Disoproxil Fumarate and Emtricitabine

scientific article published on 9 June 2016

Plasma bile acid concentrations in patients with human immunodeficiency virus infection receiving protease inhibitor therapy: possible implications for hepatotoxicity

scientific article

Poor correlation between 6beta-hydroxycortisol:cortisol molar ratios and midazolam clearance as measure of hepatic CYP3A activity

scientific article published in August 2006

Population pharmacokinetics of metronidazole evaluated using scavenged samples from preterm infants

scientific article published on 17 January 2012

Population pharmacokinetics of piperacillin using scavenged samples from preterm infants

scientific article

Pre-exposure prophylaxis for HIV prevention: how to predict success

scientific article published on 6 December 2011

Precision Dosing: Public Health Need, Proposed Framework, and Anticipated Impact.

scientific article published on 10 August 2017

Predicting Efavirenz Concentrations in the Brain Tissue of HIV-Infected Individuals and Exploring their Relationship to Neurocognitive Impairment

article

Preexposure prophylaxis for HIV infection among African women

scientific article (publication date: 2 August 2012)

Pregnancy-Related Hormones Increase Nifedipine Metabolism in Human Hepatocytes by Inducing CYP3A4 Expression

scientific article published on 12 September 2020

Prevention of SIV rectal transmission and priming of T cell responses in macaques after local pre-exposure application of tenofovir gel

scientific article

Proof-of-Principle for Immune Control of Global HIV-1 Reactivation In Vivo

scientific article published on 16 March 2015

Protease inhibitor and nonnucleoside reverse transcriptase inhibitor concentrations in the genital tract of HIV-1-infected women

scientific article

Protein binding of lopinavir and ritonavir during 4 phases of pregnancy: implications for treatment guidelines.

scientific article published on May 2013

Quantification of 3-month intraindividual variability and the influence of sex and menstrual cycle phase on CYP3A activity as measured by phenotyping with intravenous midazolam*

scientific article published on September 1, 1998

Quantifying the HIV-1 integrase inhibitor raltegravir in female genital tract secretions using high-performance liquid chromatography with ultraviolet detection

scientific article

Quantitation of three-month intraindividual variability and influence of sex and menstrual cycle phase on CYP1A2, N-acetyltransferase-2, and xanthine oxidase activity determined with caffeine phenotyping*

scientific article published on May 1, 1998

Quantitative Imaging Analysis of the Spatial Relationship between Antiretrovirals, Reverse Transcriptase Simian-Human Immunodeficiency Virus RNA, and Fibrosis in the Spleens of Nonhuman Primates

scientific article published on 20 July 2022

Quantitative analysis of microbicide concentrations in fluids, gels and tissues using confocal Raman spectroscopy

scientific article (publication date: 2013)

Quantitative mass spectrometry imaging of emtricitabine in cervical tissue model using infrared matrix-assisted laser desorption electrospray ionization

scientific article

RMP-02/MTN-006: A phase 1 rectal safety, acceptability, pharmacokinetic, and pharmacodynamic study of tenofovir 1% gel compared with oral tenofovir disoproxil fumarate

scientific article

Raltegravir pharmacokinetics in treatment-naive patients is not influenced by race: results from the raltegravir early therapy in African-Americans living with HIV (REAL) study

scientific article published on 26 November 2012

Randomized Pharmacokinetic Crossover Study Comparing 2 Curcumin Preparations in Plasma and Rectal Tissue of Healthy Human Volunteers

scientific article published on 9 August 2016

Randomized study of dual versus single ritonavir-enhanced protease inhibitors for protease inhibitor-experienced patients with HIV.

scientific article published in March 2008

Rilpivirine Plasma and Cervicovaginal Concentrations in Women During Pregnancy and Postpartum

scientific article published on 01 July 2018

Ritonavir, saquinavir, and efavirenz, but not nevirapine, inhibit bile acid transport in human and rat hepatocytes

scientific article published on 23 May 2006

Rivaroxaban Precision Dosing Strategy for Real World Atrial Fibrillation Patients

scientific article published on 08 April 2020

Roundtable Report: Importance of Antiretroviral Drug Concentrations in Sanctuary Sites and Viral Reservoirs ⬇️

scientific article published on 01 March 2003

S-Warfarin Limited Sampling Models to Estimate Area Under the Concentration Versus Time Curve for Cytochrome P450 2C9 Baseline Activity and After Induction

scientific article published on 23 January 2016

Saquinavir Loaded Acetalated Dextran Microconfetti - a Long Acting Protease Inhibitor Injectable.

scientific article published on 6 May 2016

Seminal Tenofovir Concentrations, Viral Suppression, and Semen Quality With Tenofovir Alafenamide, Compared With Tenofovir Disoproxil Fumarate (Spanish HIV/AIDS Research Network, PreEC/RIS 40)

scientific article published on 01 September 2019

Sensitive tenofovir resistance screening of HIV-1 from the genital and blood compartments of women with breakthrough infections in the CAPRISA 004 tenofovir gel trial

scientific article

Sex hormones regulate tenofovir-diphosphate in female reproductive tract cells in culture

scientific article

Short communication: cheminformatics analysis to identify predictors of antiviral drug penetration into the female genital tract

scientific article

Simian Immunodeficiency Virus Persistence in Cellular and Anatomic Reservoirs in Antiretroviral Therapy-Suppressed Infant Rhesus Macaques

scholarly article by Maud Mavigner et al published 15 September 2018 in Journal of Virology

Simple and rapid quantification of the non-nucleoside reverse transcriptase inhibitors nevirapine, delavirdine, and efavirenz in human blood plasma using high-performance liquid chromatography with ultraviolet absorbance detection

scientific article published in July 2002

Simultaneous determination of 17 antiretroviral drugs in human plasma for quantitative analysis with liquid chromatography-tandem mass spectrometry

scientific article

Simultaneous determination of six HIV nucleoside analogue reverse transcriptase inhibitors and nevirapine by liquid chromatography with ultraviolet absorbance detection

scientific article

Simultaneous quantification of emtricitabine and tenofovir in human plasma using high-performance liquid chromatography after solid phase extraction

scientific article published in August 2005

Single and multiple dose pharmacokinetics of dolutegravir in the genital tract of HIV-negative women

scientific article

Single and multiple dose pharmacokinetics of maraviroc in saliva, semen, and rectal tissue of healthy HIV-negative men.

scientific article

Single plasma concentrations of 1'-hydroxymidazolam or the ratio of 1'-hydroxymidazolam:midazolam do not predict midazolam clearance in healthy subjects

scientific article published in October 2002

Single- and multiple-dose pharmacokinetics of darunavir plus ritonavir and etravirine in semen and rectal tissue of HIV-negative men.

scientific article

Single-dose pharmacokinetics of tenofovir alafenamide and its active metabolite in the mucosal tissues

scientific article

Smartphone-Based Contingency Management Intervention to Improve Pre-Exposure Prophylaxis Adherence: Pilot Trial

scientific article

Studies on antiretroviral drug concentrations in breast milk: validation of a liquid chromatography-tandem mass spectrometric method for the determination of 7 anti-human immunodeficiency virus medications

scientific article

Suppression of human immunodeficiency virus type 1 (HIV-1) viremia with reverse transcriptase and integrase inhibitors, CD4+ T-cell recovery, and viral rebound upon interruption of therapy in a new model for HIV treatment in the humanized Rag2-/-{ga

scientific article published on 03 June 2009

Tenofovir Gel for the Prevention of Herpes Simplex Virus Type 2 Infection

scientific article

Tenofovir diphosphate and emtricitabine triphosphate concentrations in blood cells compared with isolated peripheral blood mononuclear cells: a new measure of antiretroviral adherence?

scientific article

The North Carolina contribution to the CAPRISA 004 study: the Global Health Initiative in action ⬇️

scientific article published on September 1, 2010

The influence of CYP3A5 genotype on dexamethasone induction of CYP3A activity in African Americans

scientific article published on 19 May 2008

The influence of sex, ethnicity, and CYP2B6 genotype on bupropion metabolism as an index of hepatic CYP2B6 activity in humans

scientific article

The pharmacokinetics and viral activity of tenofovir in the male genital tract

scientific article published on March 2008

The pharmacokinetics of silymarin is altered in patients with hepatitis C virus and nonalcoholic Fatty liver disease and correlates with plasma caspase-3/7 activity

scientific article published on 19 June 2008

The pharmacokinetics, safety, and initial virologic response of a triple-protease inhibitor salvage regimen containing amprenavir, saquinavir, and ritonavir

scientific article

The pharmacology of HIV-1 antiretrovirals differs between macaques and humans

scientific article published on 17 June 2022

The role of menopause in tenofovir diphosphate and emtricitabine triphosphate concentrations in cervical tissue

scientific article published on 2 November 2017

Topical microbicides and HIV prevention in the female genital tract

scientific article

Translational Approach to Predicting the Efficacy of Maraviroc-Based Regimens as HIV Preexposure Prophylaxis

scientific article published on 27 January 2020

Ultra-long-acting removable drug delivery system for HIV treatment and prevention

scientific article published in Nature Communications

Ultra-long-acting tunable biodegradable and removable controlled release implants for drug delivery

scientific article published on 20 September 2019

Unreported antiretroviral use by HIV-1-infected participants enrolling in a prospective research study

scientific article published on February 2014

Use of antiretroviral drugs to prevent sexual transmission of HIV.

scientific article

Using Real-Time Adherence Feedback to Enhance Communication About Adherence to Antiretroviral Therapy: Patient and Clinician Perspectives

scientific article published on 01 January 2020

Validation of an LC-MS/MS assay to simultaneously monitor the intracellular active metabolites of tenofovir, emtricitabine, and lamivudine in dried blood spots

scientific article published on 31 October 2017

Variability in drug metabolizing enzyme activity in HIV-infected patients

scientific article

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