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List of works by Barbara L Shacklett

A randomized, controlled trial of raltegravir intensification in antiretroviral-treated, HIV-infected patients with a suboptimal CD4+ T cell response

scientific article

Abundant expression of granzyme A, but not perforin, in granules of CD8+ T cells in GALT: implications for immune control of HIV-1 infection

scientific article

Activation, exhaustion, and persistent decline of the antimicrobial MR1-restricted MAIT-cell population in chronic HIV-1 infection

scientific article published on 13 December 2012

Amplification of low-frequency antiviral CD8 T cell responses using autologous dendritic cells

scientific article published in January 2002

Analysis of the vif gene of feline immunodeficiency virus.

scientific article published on November 1994

Beyond 51Cr release: New methods for assessing HIV-1-specific CD8+ T cell responses in peripheral blood and mucosal tissues.

scientific article

Can the new humanized mouse model give HIV research a boost

scientific article

Changes in Circulating B Cell Subsets Associated with Aging and Acute SIV Infection in Rhesus Macaques

scientific article

Characterization of HIV-1-Specific Cytotoxic T Lymphocytes Expressing the Mucosal Lymphocyte Integrin CD103 in Rectal and Duodenal Lymphoid Tissue of HIV-1-Infected Subjects

article

Co-immunization with IL-15 enhances cellular immune responses induced by a vif-deleted simian immunodeficiency virus proviral DNA vaccine and confers partial protection against vaginal challenge with SIVmac251.

scientific article published on 3 February 2009

Correlates of nontransmission in US women at high risk of human immunodeficiency virus type 1 infection through sexual exposure

scientific article published on 17 January 2002

Cryopreservation of Human Mucosal Leukocytes

scientific article

Cryopreservation of human mucosal tissues

scientific article published in PLoS ONE

Dendritic cell amplification of HIV type 1-specific CD8+ T cell responses in exposed, seronegative heterosexual women.

scientific article published in July 2002

Detection of macaque perforin expression and release by flow cytometry, immunohistochemistry, ELISA, and ELISpot

article

Differential Expression of CD8+ T Cell Cytotoxic Effector Molecules in Blood and Gastrointestinal Mucosa in HIV-1 Infection

scientific article published on 19 January 2018

Direct ex vivo measurement of CD8(+) T-lymphocyte responses to human parvovirus B19.

scientific article published on January 2001

Does per-act HIV-1 transmission risk through anal sex vary by gender? An updated systematic review and meta-analysis

article

Dynamic MAIT cell response with progressively enhanced innateness during acute HIV-1 infection

scientific article published on 14 January 2020

Effects of depot-medroxyprogesterone acetate on the immune microenvironment of the human cervix and endometrium: implications for HIV susceptibility.

scientific article

Effects of progestin-only contraceptives on the phenotype and function of female reproductive tract CD4+ and CD8+ T cells.

scientific article published on 27 May 2014

Effects of the levonorgestrel-releasing intrauterine device on the immune microenvironment of the human cervix and endometrium

scientific article published on August 2016

Enhanced ELISPOT detection of antigen-specific T cell responses from cryopreserved specimens with addition of both IL-7 and IL-15--the Amplispot assay.

scientific article

Features of the SIVmac transmembrane glycoprotein cytoplasmic domain that are important for Env functions

scientific article published on 01 March 1998

HIV Infection and Gut Mucosal Immune Function: Updates on Pathogenesis with Implications for Management and Intervention.

scientific article

HIV persists in CCR6+CD4+ T cells from colon and blood during antiretroviral therapy

scientific article

HIV-infected individuals with low CD4/CD8 ratio despite effective antiretroviral therapy exhibit altered T cell subsets, heightened CD8+ T cell activation, and increased risk of non-AIDS morbidity and mortality

scientific article

HIVR4P 2016, Partnering for Prevention: Conference Summary and Highlights

scientific article

How common and frequent is heterosexual anal intercourse among South Africans? A systematic review and meta-analysis

scientific article

Immune responses to HIV and SIV in mucosal tissues: 'location, location, location'.

scientific article

Immune responses to HIV in the female reproductive tract, immunologic parallels with the gastrointestinal tract, and research implications

scientific article

Immunodominant HIV-Specific CD8+T-Cell Responses Are Common to Blood and Gastrointestinal Mucosa, and Gag-Specific Responses Dominate in Rectal Mucosa of HIV Controllers ⬇️

scientific article published on July 28, 2010

Impact of highly active antiretroviral therapy initiation on CD4(+) T-cell repopulation in duodenal and rectal mucosa.

scientific article

Importance of the intracytoplasmic domain of the simian immunodeficiency virus (SIV) envelope glycoprotein for pathogenesis.

scientific article published in December 1998

Increased Frequency of Regulatory T Cells Accompanies Increased Immune Activation in Rectal Mucosae of HIV-Positive Noncontrollers ⬇️

scientific article published on August 31, 2011

Increased adhesion molecule and chemokine receptor expression on CD8+ T cells trafficking to cerebrospinal fluid in HIV-1 infection.

scientific article published on 24 May 2004

Interactions of the cytoplasmic domains of human and simian retroviral transmembrane proteins with components of the clathrin adaptor complexes modulate intracellular and cell surface expression of envelope glycoproteins

scientific article

Isolation of Cytomegalovirus-Specific Cytotoxic T-Lymphocytes from Gut-Associated Lymphoid Tissue (GALT) of HIV Type 1-Infected Subjects

article

Magnitude and complexity of rectal mucosa HIV-1-specific CD8+ T-cell responses during chronic infection reflect clinical status

scientific article

Mucosal T-cell responses to HIV: responding at the front lines

scientific article

Mucosal immunity in HIV controllers: the right place at the right time.

scientific article published on May 2011

Multidrug-resistant, dual-tropic HIV-1 and rapid progression

Multifunctional human immunodeficiency virus (HIV) gag-specific CD8+ T-cell responses in rectal mucosa and peripheral blood mononuclear cells during chronic HIV type 1 infection.

scientific article published on 7 March 2007

Myeloid dendritic cells isolated from tissues of SIV-infected Rhesus macaques promote the induction of regulatory T cells ⬇️

scientific article published on January 28, 2012

Nine-color flow cytometry for accurate measurement of T cell subsets and cytokine responses. Part II: Panel performance across different instrument platforms.

scientific article published in May 2008

Optimization of methods to assess human mucosal T-cell responses to HIV infection.

scientific article published in August 2003

Perforin expression in the gastrointestinal mucosa is limited to acute simian immunodeficiency virus infection

scientific article

Phenotype and functionality of CD4+ and CD8+ T cells in the upper reproductive tract of healthy premenopausal women

scientific article published on 06 December 2013

Predominance of weakly cytotoxic, T-betLowEomesNeg CD8+ T-cells in human gastrointestinal mucosa: implications for HIV infection.

scientific article

Prospective antiretroviral treatment of asymptomatic, HIV-1 infected controllers

scientific article

Quantification of HIV-1-specific T-cell responses at the mucosal cervicovaginal surface

article

Quantifying HIV-1-specific CD8 (+) T-cell responses using ELISPOT and cytokine flow cytometry.

scientific article

Randomized pilot trial of a synbiotic dietary supplement in chronic HIV-1 infection

scientific article

Receptive anal sex contributes substantially to heterosexually-acquired HIV infections among at-risk women in Twenty US Cities: results from a modelling analysis

scientific article published on 08 May 2020

Regulation of gene expression directed by the long terminal repeat of the feline immunodeficiency virus ⬇️

scientific article published on March 1, 1992

Seroconversion following nonoccupational postexposure prophylaxis against HIV.

scientific article published on 13 October 2005

Short Communication: HIV+ Viremic Slow Progressors Maintain Low Regulatory T Cell Numbers in Rectal Mucosa but Exhibit High T Cell Activation ⬇️

scientific article published on October 16, 2012

Single-copy assay quantification of HIV-1 RNA in paired cerebrospinal fluid and plasma samples from elite controllers

scientific article published on April 2013

The immunologic effects of maraviroc intensification in treated HIV-infected individuals with incomplete CD4+ T-cell recovery: a randomized trial

scientific article published on 15 April 2013

The intracytoplasmic domain of the Env transmembrane protein is a locus for attenuation of simian immunodeficiency virus SIVmac in rhesus macaques.

scientific article

The rhesus macaque CCR3 chemokine receptor is a cell entry cofactor for HIV-2, but not for HIV-1.

scientific article

Trafficking of human immunodeficiency virus type 1-specific CD8+ T cells to gut-associated lymphoid tissue during chronic infection

scientific article

Understanding the "lucky few": the conundrum of HIV-exposed, seronegative individuals.

scientific article

Unexpected Inflammatory Effects of Intravaginal Gels (Universal Placebo Gel and Nonoxynol-9) on the Upper Female Reproductive Tract: A Randomized Crossover Study.

scientific article published on 15 July 2015

Utilizing a TLR5-Adjuvanted Cytomegalovirus as a Lentiviral Vaccine in the Nonhuman Primate Model for AIDS.

scientific article

Viral sanctuaries during highly active antiretroviral therapy in a nonhuman primate model for AIDS

scientific article

Viral suppression and immune restoration in the gastrointestinal mucosa of human immunodeficiency virus type 1-infected patients initiating therapy during primary or chronic infection

scientific article

Will loss of your MAITs weaken your HAART [corrected]?

scientific article published on October 2013

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