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List of works by Vladimir J. Kefalov

A Mixture of U.S. Food and Drug Administration-Approved Monoaminergic Drugs Protects the Retina From Light Damage in Diverse Models of Night Blindness

scientific article published on 01 April 2019

A new mouse model for stationary night blindness with mutant Slc24a1 explains the pathophysiology of the associated human disease.

scientific article

Age-related deterioration of rod vision in mice.

scientific article

An allosteric regulator of R7-RGS proteins influences light-evoked activity and glutamatergic waves in the inner retina

scientific article

An alternative pathway mediates the mouse and human cone visual cycle.

scientific article published on 24 September 2009

Apo-Opsin Exists in Equilibrium Between a Predominant Inactive and a Rare Highly Active State

scientific article published on 20 November 2018

Autophagy supports color vision.

scientific article published on 20 August 2015

Autosomal recessive retinitis pigmentosa E150K opsin mice exhibit photoreceptor disorganization.

scientific article published on 10 December 2012

Breaking the covalent bond--a pigment property that contributes to desensitization in cones.

scientific article

CRALBP supports the mammalian retinal visual cycle and cone vision

scientific article

Chromophore supply rate-limits mammalian photoreceptor dark adaptation.

scientific article

Circadian and light-driven regulation of rod dark adaptation

scientific article

Conditional deletion of Des1 in the mouse retina does not impair the visual cycle in cones

scientific article published on 15 January 2019

Cone phosphodiesterase-6α' restores rod function and confers distinct physiological properties in the rod phosphodiesterase-6β-deficient rd10 mouse

scientific article published on July 2013

Cone-driven retinal responses are shaped by rod but not cone HCN1

Cyp27c1 Red-Shifts the Spectral Sensitivity of Photoreceptors by Converting Vitamin A1 into A2.

scientific article

DICER1 is essential for survival of postmitotic rod photoreceptor cells in mice.

scientific article

Deletion of GRK1 causes retina degeneration through a transducin-independent mechanism.

scientific article

Dephosphorylation by protein phosphatase 2A regulates visual pigment regeneration and the dark adaptation of mammalian photoreceptors. ⬇️

scientific article published on 23 October 2017

Development of an MRI biomarker sensitive to tetrameric visual arrestin 1 and its reduction via light-evoked translocation in vivo

scientific article

Differential impact of Kv8.2 loss on rod and cone signaling and degeneration

Effect of 11-cis 13-demethylretinal on phototransduction in bleach-adapted rod and cone photoreceptors.

scientific article

Effect of g protein-coupled receptor kinase 1 (Grk1) overexpression on rod photoreceptor cell viability

scientific article

Essential and synergistic roles of RP1 and RP1L1 in rod photoreceptor axoneme and retinitis pigmentosa

scientific journal article

Ex vivo ERG analysis of photoreceptors using an in vivo ERG system.

scientific article

Examining the Role of Cone-expressed RPE65 in Mouse Cone Function

scientific article published in Scientific Reports

FASEB Science Research Conference on Biology and Chemistry of Vision

Function of mammalian M-cones depends on the level of CRALBP in Müller cells

scientific article published on 01 January 2021

Functional interchangeability of rod and cone transducin alpha-subunits.

scholarly article

G-protein betagamma-complex is crucial for efficient signal amplification in vision

scientific article

GUCY2D Cone-Rod Dystrophy-6 is a 'Phototransduction Disease' Triggered by Abnormal Calcium Feedback on Retinal Membrane Guanylyl Cyclase 1.

scientific article published on 12 February 2018

Graded gene expression changes determine phenotype severity in mouse models of CRX-associated retinopathies

scientific article

Guanylate cyclase-activating protein 2 contributes to phototransduction and light adaptation in mouse cone photoreceptors

scientific article published on 16 March 2018

Human infrared vision is triggered by two-photon chromophore isomerization

scientific article

Interphotoreceptor retinoid-binding protein as the physiologically relevant carrier of 11-cis-retinol in the cone visual cycle

scientific article published on March 2011

Intra-retinal visual cycle required for rapid and complete cone dark adaptation.

scientific article published in February 2009

Investigating the Ca-dependent and Ca-independent mechanisms for mammalian cone light adaptation

scientific article published in Scientific Reports

LRIT1 Modulates Adaptive Changes in Synaptic Communication of Cone Photoreceptors

scientific article published in March 2018

Lamin B1 and lamin B2 are long-lived proteins with distinct functions in retinal development.

scientific article published on 13 April 2016

Light deprivation reduces the severity of experimental diabetic retinopathy

scientific article published on 21 January 2020

Membrane anchoring subunits specify selective regulation of RGS9·Gbeta5 GAP complex in photoreceptor neurons

scientific article published on October 2010

Mislocalization of cone nuclei impairs cone function in mice

scientific article published on 15 June 2020

Mitochondrial Calcium Uniporter (MCU) deficiency reveals an alternate path for Ca2+ uptake in photoreceptor mitochondria

scientific article published on 29 September 2020

Molecular properties of rhodopsin and rod function

scientific article

Multiple Isoforms of Nesprin1 Are Integral Components of Ciliary Rootlets.

scientific article published on 9 June 2017

Occupancy of the chromophore binding site of opsin activates visual transduction in rod photoreceptors

scientific article

P23H opsin knock-in mice reveal a novel step in retinal rod disc morphogenesis

scientific article

Phosducin-like protein 1 is essential for G-protein assembly and signaling in retinal rod photoreceptors

scientific article

Phosphorylation at Serine 21 in G protein-coupled receptor kinase 1 (GRK1) is required for normal kinetics of dark adaption in rod but not cone photoreceptors

scientific article published on 30 December 2019

Photoreceptors in a mouse model of Leigh syndrome are capable of normal light-evoked signaling

scientific article published on 27 June 2019

Phototransduction in Rods and Cones

Physiological studies of the interaction between opsin and chromophore in rod and cone visual pigments.

scientific article published on January 2010

Protein misfolding and the pathogenesis of ABCA4-associated retinal degenerations

scientific article published on 24 February 2015

Quantal noise from human red cone pigment.

scientific article published on 20 April 2008

R9AP overexpression alters phototransduction kinetics in iCre75 mice.

scientific article published on 06 March 2014

Redox-Responsive Hyaluronic Acid-Based Nanogels for the Topical Delivery of the Visual Chromophore to Retinal Photoreceptors

scientific article published on 22 February 2021

Regulation of calcium homeostasis in the outer segments of rod and cone photoreceptors

scientific article published on 06 June 2018

Regulation of mammalian cone phototransduction by recoverin and rhodopsin kinase.

scientific article

Reprogramming of adult rod photoreceptors prevents retinal degeneration

scientific article published on 14 January 2013

Retinal cone photoreceptors require phosducin-like protein 1 for G protein complex assembly and signaling

scientific article

Retinoid isomerase inhibitors impair but do not block mammalian cone photoreceptor function.

scientific article published on 2 March 2018

Retinol dehydrogenase 8 and ATP-binding cassette transporter 4 modulate dark adaptation of M-cones in mammalian retina.

scientific article published on 9 September 2015

Rhodopsin kinase and arrestin binding control the decay of photoactivated rhodopsin and dark adaptation of mouse rods.

scientific article published on July 2016

Role of guanylyl cyclase modulation in mouse cone phototransduction.

scientific article

Role of visual pigment properties in rod and cone phototransduction

scientific article published on October 2003

Sensitivity and kinetics of signal transmission at the first visual synapse differentially impact visually-guided behavior

scientific article published on 16 April 2015

Sensitivity of Mammalian Cone Photoreceptors to Infrared Light

scientific article published on 07 August 2019

Signaling by Rod and Cone Photoreceptors: Opsin Properties, G-protein Assembly, and Mechanisms of Activation

Signaling properties of a short-wave cone visual pigment and its role in phototransduction

scientific article published in September 2007

Signaling states of rhodopsin in rod disk membranes lacking transducin βγ-complex

scientific article published on 9 March 2012

Simultaneous ex vivo functional testing of two retinas by in vivo electroretinogram system.

scientific article published on 6 May 2015

Single-cell suction recordings from mouse cone photoreceptors

scientific article published on 5 January 2010

Store-operated channels regulate intracellular calcium in mammalian rods

scientific article published on 06 June 2012

Systemic Retinaldehyde Treatment Corrects Retinal Oxidative Stress, Rod Dysfunction, and Impaired Visual Performance in Diabetic Mice

scientific article

The B3 Subunit of the Cone Cyclic Nucleotide-gated Channel Regulates the Light Responses of Cones and Contributes to the Channel Structural Flexibility

scientific article published on 18 February 2016

The Na(+)/Ca(2+), K(+) exchanger 2 modulates mammalian cone phototransduction.

scientific article published on September 2016

The Na+/Ca2+, K+ exchanger NCKX4 is required for efficient cone-mediated vision

scientific article

The cone-specific visual cycle

scientific article

The mammalian cone visual cycle promotes rapid M/L-cone pigment regeneration independently of the interphotoreceptor retinoid-binding protein

scientific article

The retina visual cycle is driven by cis retinol oxidation in the outer segments of cones.

scientific article published in January 2017

The role of retinol dehydrogenase 10 in the cone visual cycle

scientific article published on 24 May 2017

Thyroid hormone receptors mediate two distinct mechanisms of long-wavelength vision

scientific article published on 15 June 2020

Transretinal ERG Recordings from Mouse Retina: Rod and Cone Photoresponses ⬇️

scientific article published on March 14, 2012

Two-photon microperimetry: sensitivity of human photoreceptors to infrared light

scientific article published on 09 August 2019

Use of retinal analogues for the study of visual pigment function

scientific article published in January 2002

Variation in Rhodopsin Kinase Expression Alters the Dim Flash Response Shut Off and the Light Adaptation in Rod Photoreceptors

scientific article (publication date: 29 August 2011)

cis Retinol oxidation regulates photoreceptor access to the retina visual cycle and cone pigment regeneration.

scientific article

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