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List of works by Ulla G Knaus

A p21-activated kinase-controlled metabolic switch up-regulates phagocyte NADPH oxidase

scientific article

Activation of the leukocyte NADPH oxidase by protein kinase C in a partially recombinant cell-free system.

scientific article published on May 1999

Analysis of epithelial barrier integrity in polarized lung epithelial cells.

scientific article

Anti-invasive adjuvant therapy with imipramine blue enhances chemotherapeutic efficacy against glioma

scientific article

Balancing Reactive Oxygen Species in the Epigenome: NADPH Oxidases as Target and Perpetrator ⬇️

scientific article published on November 5, 2012

Cellular ROS imaging with hydro-Cy3 dye is strongly influenced by mitochondrial membrane potential.

scientific article published on 3 November 2016

Cj1411c encodes for a cytochrome P450 involved in Campylobacter jejuni 81-176 pathogenicity

scientific article (publication date: 2013)

Constitutive NADPH oxidase 4 activity resides in the composition of the B-loop and the penultimate C terminus

scientific article published on 25 January 2012

Corrigendum to "European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)" [Redox Biol. 13 (2017) 94-162].

scientific article published on 26 October 2017

Crohn's Strictures-Moving Away from the Knife

scientific article

Defects in NADPH Oxidase Genes NOX1 and DUOX2 in Very Early Onset Inflammatory Bowel Disease

scientific article

Defensive Mutualism Rescues NADPH Oxidase Inactivation in Gut Infection

scientific article published on May 2016

Effect of various polysaccharides on the complement system

scientific article published on 01 December 1988

Effects of boswellic acid of Boswellia serrata and other triterpenic acids on the complement system

scientific article published on 01 May 1996

Enhanced expression of neutrophil NADPH oxidase components in intestine of rats after burn injury

scientific article published on 01 December 1999

European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS).

scientific article published on 18 May 2017

First Identification of Biallelic Inherited DUOX2 Inactivating Mutations as a Cause of Very Early Onset Inflammatory Bowel Disease.

scientific article

Fulvene-5 potently inhibits NADPH oxidase 4 and blocks the growth of endothelial tumors in mice.

scientific article published on 13 July 2009

Functional analysis of Nox4 reveals unique characteristics compared to other NADPH oxidases

scientific article

GDP dissociation inhibitor prevents intrinsic and GTPase activating protein-stimulated GTP hydrolysis by the Rac GTP-binding protein.

scientific article published on January 1993

Genetic disorders coupled to ROS deficiency

scientific article (publication date: December 2015)

Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells

scientific article published in March 1997

Hydrogen peroxide production by lactobacilli promotes epithelial restitution during colitis.

scientific article

Immunologically active metallic ion-containing polysaccharides of Achyrocline satureioides

scientific article published on 01 August 1992

Immunomodulation of human complement system by plant extracts and isolated pure compounds

scientific article published on 01 December 1986

Impaired function of the Tie-2 receptor contributes to vascular leakage and lethality in anthrax ⬇️

scientific article published on June 4, 2012

Inhibitory action of NoxA1 on dual oxidase activity in airway cells

scientific article

Interaction of the Nck adapter protein with p21-activated kinase (PAK1)

scientific article

Lung epithelial injury by B. anthracis lethal toxin is caused by MKK-dependent loss of cytoskeletal integrity

scientific article (publication date: 2009)

Mouse macrophages completely lacking Rho subfamily GTPases (RhoA, RhoB, and RhoC) have severe lamellipodial retraction defects, but robust chemotactic navigation and altered motility.

scientific article

Mucosal reactive oxygen species decrease virulence by disrupting Campylobacter jejuni phosphotyrosine signaling.

scientific article published on July 2012

N-(3-oxo-acyl)homoserine lactones signal cell activation through a mechanism distinct from the canonical pathogen-associated molecular pattern recognition receptor pathways.

scientific article published on 7 August 2006

NADPH oxidase-derived H2O2 subverts pathogen signaling by oxidative phosphotyrosine conversion to PB-DOPA.

scientific article published on 25 August 2016

NADPH oxidases and ROS signaling in the gastrointestinal tract.

scientific article

NOX1 loss-of-function genetic variants in patients with inflammatory bowel disease.

scientific article

Neutrophil migration through extracellular matrix

scientific article published on 01 January 2014

New players in TLR-mediated innate immunity: PI3K and small Rho GTPases.

scientific article

Oxidases and peroxidases in cardiovascular and lung disease: new concepts in reactive oxygen species signaling

scientific article

P21-activated kinase is required for mitotic progression and regulates Plk1.

scientific article published on 21 April 2008

PAK is required for the disruption of E-cadherin adhesion by the small GTPase Rac.

scientific article published on 4 March 2008

Pathogen control at the intestinal mucosa - H2O2 to the rescue

scientific article published on 12 January 2017

Purification and characterization of Rac 2. A cytosolic GTP-binding protein that regulates human neutrophil NADPH oxidase ⬇️

scientific article published on November 25, 1992

Purification of Rac2 from human neutrophils.

scientific article published in January 1995

Quantitative interaction analysis permits molecular insights into functional NOX4 NADPH oxidase heterodimer assembly.

scientific article published on 19 April 2018

ROS in gastrointestinal inflammation: Rescue Or Sabotage?

scientific article

Rac GTPase interacts specifically with phosphatidylinositol 3-kinase

scientific journal article

Rac GTPase isoform-specific regulation of NADPH oxidase and chemotaxis in murine neutrophils in vivo. Role of the C-terminal polybasic domain.

scientific article published on 25 October 2004

Rac activation induces NADPH oxidase activity in transgenic COSphox cells, and the level of superoxide production is exchange factor-dependent.

scientific article published on 14 March 2002

Rac and Rap GTPase activation assays.

scientific article published in January 2007

Ras-related GTP-binding proteins and leukocyte signal transduction

scientific article published on 01 January 1994

Redox regulation of genome stability by effects on gene expression, epigenetic pathways and DNA damage/repair.

scientific article published on 3 June 2015

Regulation of NADPH oxidase activity by Rac GTPase activating protein(s).

scientific article

Regulation of Nox1 activity via protein kinase A-mediated phosphorylation of NoxA1 and 14-3-3 binding.

scientific article

Rho Family GTPases Regulate p38 Mitogen-activated Protein Kinase through the Downstream Mediator Pak1 ⬇️

scientific article published on October 13, 1995

Rho GTPase signaling in inflammation and transformation.

scientific article

Rho family and Rap GTPase activation assays.

scientific article

RhoA determines disease progression by controlling neutrophil motility and restricting hyperresponsiveness

scientific article published on 29 April 2014

Roles of the Rac1 and Rac3 GTPases in human tumor cell invasion

scientific article

Structural Requirements for PAK Activation by Rac GTPases ⬇️

scientific article published on August 21, 1998

TLR4-mediated survival of macrophages is MyD88 dependent and requires TNF-alpha autocrine signalling

scientific article published on 01 March 2007

The p21Rac/Cdc42-activated kinases (PAKs) ⬇️

scientific article published on August 1, 1998

The role of small GTP-binding proteins in leukocyte function.

scientific article published on February 1994

Toll-like receptor 3 L412F polymorphism promotes a persistent clinical phenotype in pulmonary sarcoidosis.

scientific article published on 11 December 2017

Two signaling mechanisms for activation of alphaM beta2 avidity in polymorphonuclear neutrophils

scientific article published on 01 April 1998

Ubiquitin C-terminal hydrolase-L1 increases cancer cell invasion by modulating hydrogen peroxide generated via NADPH oxidase 4

scientific article

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