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List of works by Måns Ehrenberg

A cryo-electron microscopic study of ribosome-bound termination factor RF2

scientific article

A direct estimation of the context effect on the efficiency of termination

scientific article

A post-translational modification in the GGQ motif of RF2 from Escherichia coli stimulates termination of translation

scientific article published in December 2000

A tRNA body with high affinity for EF-Tu hastens ribosomal incorporation of unnatural amino acids

scientific article published on 26 March 2014

Accuracy of genetic code translation and its orthogonal corruption by aminoglycosides and Mg2+ ions

scientific article published on 18 December 2017

Accuracy of initial codon selection by aminoacyl-tRNAs on the mRNA-programmed bacterial ribosome

scientific article published on 20 July 2015

Activation of initiation factor 2 by ligands and mutations for rapid docking of ribosomal subunits ⬇️

scientific article published on December 10, 2010

Catalytic effects of elongation factor Ts on polypeptide synthesis.

scientific article

Cis-acting resistance peptides reveal dual ribosome inhibitory action of the macrolide josamycin

scientific article

Cofactor dependent conformational switching of GTPases

scientific article published on 23 May 2008

Comparison of repressor and transcriptional attenuator systems for control of amino acid biosynthetic operons

scientific article

Complementary roles of initiation factor 1 and ribosome recycling factor in 70S ribosome splitting

scientific article

Complete kinetic mechanism for recycling of the bacterial ribosome

scientific article published on 2 November 2015

Counting cycles of EF-Tu to measure proofreading in translation

scientific article published in March 1986

Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A.

scientific article published in June 2018

Cryo-EM visualization of the ribosome in termination complex with apo-RF3 and RF1.

scientific article published on 4 June 2013

Determinants of the rate of mRNA translocation in bacterial protein synthesis

scientific article

Dissociation rates of peptidyl-tRNA from the P-site of E.coli ribosomes.

scientific article published on March 1996

Drug efflux pump deficiency and drug target resistance masking in growing bacteria

scholarly article

Error-prone initiation factor 2 mutations reduce the fitness cost of antibiotic resistance

scientific article published on 3 February 2010

Erythromycin resistance by L4/L22 mutations and resistance masking by drug efflux pump deficiency

scientific article published on 5 February 2009

Fast evaluation of fluctuations in biochemical networks with the linear noise approximation

scientific article

Fast recycling of Escherichia coli ribosomes requires both ribosome recycling factor (RRF) and release factor RF3 ⬇️

scientific article published on July 1, 1997

Fluctuations and quality of control in biological cells: zero-order ultrasensitivity reinvestigated

scientific article

Fluctuations in repressor control: thermodynamic constraints on stochastic focusing

scientific article

Fusidic acid targets elongation factor G in several stages of translocation on the bacterial ribosome

scientific article

Genetic code translation displays a linear trade-off between efficiency and accuracy of tRNA selection

scientific article published on 21 December 2011

Guanine-nucleotide exchange on ribosome-bound elongation factor G initiates the translocation of tRNAs

scientific article

How initiation factors maximize the accuracy of tRNA selection in initiation of bacterial protein synthesis.

scientific article

How initiation factors tune the rate of initiation of protein synthesis in bacteria

scientific article published on 25 May 2006

Hyper-accurate ribosomes inhibit growth

scientific article published on November 1984

Identification of enzyme inhibitory mechanisms from steady-state kinetics ⬇️

scientific article published on June 12, 2011

Incorporation of aminoacyl-tRNA into the ribosome as seen by cryo-electron microscopy

scientific article

Initiation factors IF1 and IF2 synergistically remove peptidyl-tRNAs with short polypeptides from the P-site of translating Escherichia coli ribosomes ⬇️

scientific article published on August 14, 1998

Initiation of Escherichia coli ribosomes on matrix coupled mRNAs studied by optical biosensor technique

scientific article

Interactions of the release factor RF1 with the ribosome as revealed by cryo-EM.

scientific article published on 30 January 2006

Interplay of signal recognition particle and trigger factor at L23 near the nascent chain exit site on the Escherichia coli ribosome

scientific article published on 19 May 2003

Is there proofreading during polypeptide synthesis?

scientific article published on January 1982

Is translation inhibited by noncognate ternary complexes?

scientific article

Key Intermediates in Ribosome Recycling Visualized by Time-Resolved Cryoelectron Microscopy

scientific article

Kinetic properties of Escherichia coli ribosomes with altered forms of S12

scientific article published on April 20, 1992

Kinetics of macrolide action: the josamycin and erythromycin cases

scientific article

Locking and unlocking of ribosomal motions

scientific article

Mapping the interaction of SmpB with ribosomes by footprinting of ribosomal RNA

scientific article

Mechanism for the disassembly of the posttermination complex inferred from cryo-EM studies

scientific article published on June 2005

Mechanism of fusidic acid inhibition of RRF- and EF-G-dependent splitting of the bacterial post-termination ribosome

scientific article

Molecular clocks reduce plasmid loss rates: the R1 case

scientific article

Molecular mechanism of viomycin inhibition of peptide elongation in bacteria

scientific article published on 11 January 2016

Mutants of EF-Tu defective in binding aminoacyl-tRNA.

scientific article published in March 1996

Mutations in 23 S ribosomal RNA perturb transfer RNA selection and can lead to streptomycin dependence.

scientific article

Mutations in ribosomal proteins L7/L12 perturb EF-G and EF-Tu functions.

scientific article

Near-critical behavior of aminoacyl-tRNA pools in E. coli at rate-limiting supply of amino acids

scientific article published on 22 October 2004

Near-critical phenomena in intracellular metabolite pools

scientific article

On the pH dependence of class-1 RF-dependent termination of mRNA translation

scientific article published on 23 January 2015

Optimal control of gene expression for fast proteome adaptation to environmental change

scientific article published on 02 December 2013

Origins of minigene-dependent growth inhibition in bacterial cells

scientific article

Over expression of a tRNA(Leu) isoacceptor changes charging pattern of leucine tRNAs and reveals new codon reading

scientific article published on 5 October 2005

Peptide formation by N-methyl amino acids in translation is hastened by higher pH and tRNA(Pro).

scientific article

Peptidyl-tRNA regulates the GTPase activity of translation factors

scientific article

Positive allosteric feedback regulation of the stringent response enzyme RelA by its product

scientific article published on 20 July 2012

Pre-binding of small protein B to a stalled ribosome triggers trans-translation

scientific article

Proofreading neutralizes potential error hotspots in genetic code translation by transfer RNAs

scientific article

Purification of active Escherichia coli ribosome recycling factor (RRF) from an osmo-regulated expression system.

scientific article

RF3 induces ribosomal conformational changes responsible for dissociation of class I release factors

scientific article

Random Signal Fluctuations Can Reduce Random Fluctuations in Regulated Components of Chemical Regulatory Networks

scientific article

Rate and accuracy of bacterial protein synthesis revisited

scientific article

Recognition of aminoacyl-tRNA: a common molecular mechanism revealed by cryo-EM

scientific article

Regulatory nascent peptides in the ribosomal tunnel

scientific article

Reiterative Synthesis by the Ribosome and Recognition of the N-Terminal Formyl Group by Biosynthetic Machinery Contribute to Evolutionary Conservation of the Length of Antibiotic Microcin C Peptide Precursor

scientific article published in 2019

Release factor RF3 in E.coli accelerates the dissociation of release factors RF1 and RF2 from the ribosome in a GTP-dependent manner ⬇️

scientific article published on July 1, 1997

Release of peptide promoted by the GGQ motif of class 1 release factors regulates the GTPase activity of RF3.

scientific article

Ribosomal RNA and protein mutants resistant to spectinomycin

scientific article published on March 1990

Ribosome bypassing at serine codons as a test of the model of selective transfer RNA charging

scientific article

Ribosome release factor RF4 and termination factor RF3 are involved in dissociation of peptidyl-tRNA from the ribosome ⬇️

scientific article published on February 2, 1998

Ribosome rescue by tmRNA requires truncated mRNAs

scientific article published in April 2004

Ribosome-induced changes in elongation factor Tu conformation control GTP hydrolysis

scientific article

Ribosomes lacking protein S20 are defective in mRNA binding and subunit association

scientific article published on 10 February 2010

Selective charging of tRNA isoacceptors induced by amino-acid starvation

scientific article

Simultaneous binding of trigger factor and signal recognition particle to the E. coli ribosome.

scientific article

Slow peptide bond formation by proline and other N-alkylamino acids in translation

scientific article

Specific Interaction between EF-G and RRF and Its Implication for GTP-Dependent Ribosome Splitting into Subunits

scientific article

Spontaneous separation of bi-stable biochemical systems into spatial domains of opposite phases

scientific article

Stop codon recognition and interactions with peptide release factor RF3 of truncated and chimeric RF1 and RF2 from Escherichia coli.

scientific article

Structure of the Escherichia coli ribosomal termination complex with release factor 2

scientific article

Structure probing of tmRNA in distinct stages of trans-translation

scientific article published on 30 March 2007

Synthesis of region-labelled proteins for NMR studies by in vitro translation of column-coupled mRNAs ⬇️

scientific article published on July 1, 1997

Systems Biology: Nobel Symposium 146.

scientific article

Systems biology is taking off.

scientific article

Targeting and insertion of heterologous membrane proteins in E. coli

scientific article published in July 2003

Termination of translation: interplay of mRNA, rRNAs and release factors?

scientific article

The Impact of Aminoglycosides on the Dynamics of Translation Elongation

scientific article

The Logic of Life

scientific article

The SAXS solution structure of RF1 differs from its crystal structure and is similar to its ribosome bound cryo-EM structure

scientific article published on December 2005

The bacterial toxin RelE induces specific mRNA cleavage in the A site of the eukaryote ribosome

scientific article

The cryo-EM structure of a translation initiation complex from Escherichia coli

scientific article

The hemK gene in Escherichia coli encodes the N(5)-glutamine methyltransferase that modifies peptide release factors

scientific article

The kinetics of ribosomal peptidyl transfer revisited

scientific article

The mechanism of action of macrolides, lincosamides and streptogramin B reveals the nascent peptide exit path in the ribosome

scientific article

The molecular mechanism of peptide-mediated erythromycin resistance

scientific article published on 12 January 2006

The pretranslocation ribosome is targeted by GTP-bound EF-G in partially activated form

scholarly article

The role of ribosomal protein L11 in class I release factor-mediated translation termination and translational accuracy

scientific article

The role of tRNA as a molecular spring in decoding, accommodation, and peptidyl transfer

scientific article

The roles of initiation factor 2 and guanosine triphosphate in initiation of protein synthesis ⬇️

scientific article published on October 15, 2003

Thermodynamic modeling of variations in the rate of RNA chain elongation of E. coli rrn operons

scientific article published on January 2014

Trade-off between segregational stability and metabolic burden: a mathematical model of plasmid ColE1 replication control 1 1Edited by D Draper ⬇️

scientific article published on May 29, 1998

Transcriptional accuracy modeling suggests two-step proofreading by RNA polymerase

scientific article published on 28 September 2017

Trigger factor binding to ribosomes with nascent peptide chains of varying lengths and sequences.

scientific article

What makes ribosome-mediated transcriptional attenuation sensitive to amino acid limitation?

scientific article

pH-sensitivity of the ribosomal peptidyl transfer reaction dependent on the identity of the A-site aminoacyl-tRNA.

scientific article

tRNA-ribosome interactions

scientific article published on November 1995

tmRNA-induced release of messenger RNA from stalled ribosomes

scientific article published in July 2005

tmRNA.SmpB complex mimics native aminoacyl-tRNAs in the A site of stalled ribosomes

scientific article

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