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List of works by Alistair M Chalk

A cross-study transcriptional analysis of Parkinson's disease

scientific article

A rescue strategy for multimapping short sequence tags refines surveys of transcriptional activity by CAGE.

scientific article

ADAR1, inosine and the immune sensing system: distinguishing self from non-self

scientific article

Activation of PTHrP-cAMP-CREB1 signaling following p53 loss is essential for osteosarcoma initiation and maintenance.

scientific article published on 12 April 2016

Adenosine-to-inosine RNA editing by ADAR1 is essential for normal murine erythropoiesis.

scientific article published on 30 June 2016

Alternate transcription of the Toll-like receptor signaling cascade

scientific article published on 17 February 2006

BET inhibitors induce apoptosis through a MYC independent mechanism and synergise with CDK inhibitors to kill osteosarcoma cells

scientific article published on 6 May 2015

Computational antisense oligo prediction with a neural network model

scientific article published in December 2002

Defining the functions of adenosine-to-inosine RNA editing through hematology

scientific article published on 01 July 2019

Differential regulation of osteoadherin (OSAD) by TGF-beta1 and BMP-2

scientific article published on 30 August 2006

Disease-specific, neurosphere-derived cells as models for brain disorders

scientific article published on 10 August 2010

Focusing on RISC assembly in mammalian cells

scientific article published on 4 February 2008

Gene expression profiling to define the cell intrinsic role of the SKI proto-oncogene in hematopoiesis and myeloid neoplasms

scientific article

Genome-wide detection and analysis of hippocampus core promoters using DeepCAGE.

scientific article

Genome-wide review of transcriptional complexity in mouse protein kinases and phosphatases.

scientific article

Hematopoietic stem and progenitor cell-restricted Cdx2 expression induces transformation to myelodysplasia and acute leukemia

scientific article published on 15 June 2020

Improved and automated prediction of effective siRNA.

scientific article published in June 2004

Increased miR-155-5p and reduced miR-148a-3p contribute to the suppression of osteosarcoma cell death.

scientific article published on 04 April 2016

Knockdown of PTHR1 in osteosarcoma cells decreases invasion and growth and increases tumor differentiation in vivo

scientific article published on 21 July 2014

Modeling distinct osteosarcoma subtypes in vivo using Cre:lox and lineage-restricted transgenic shRNA.

scientific article published on 26 February 2013

Profiled support vector machines for antisense oligonucleotide efficacy prediction

scientific article

Protein recoding by ADAR1-mediated RNA editing is not essential for normal development and homeostasis.

scientific article published on 5 September 2017

RNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonself

scientific article

RNAi screen indicates widespread biological function for human natural antisense transcripts

scientific article

Rapid SNP diagnostics using asymmetric isothermal amplification and a new mismatch-suppression technology

scientific article published on 18 February 2007

Sfixem--graphical sequence feature display in Java

scientific article published on 15 April 2004

Srsf2P95Hinitiates myeloid bias and myelodysplastic/myeloproliferative syndrome (MDS/MPN) from hemopoietic stem cells

article

Systematic Screening Identifies Dual PI3K and mTOR Inhibition as a Conserved Therapeutic Vulnerability in Osteosarcoma

scientific article published on 10 April 2015

The Rothmund-Thomson syndrome helicase RECQL4 is essential for hematopoiesis

scientific article

The SKI proto-oncogene enhances the in vivo repopulation of hematopoietic stem cells and causes myeloproliferative disease.

scientific article published on 10 January 2014

The majority of A-to-I RNA editing is not required for mammalian homeostasis

scientific article published on 09 December 2019

The transcriptional landscape of the mammalian genome

scientific article

The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line.

scientific article

Using CAGE Data for Quantitative Expression

Wnt inhibitory factor 1 (WIF1) is a marker of osteoblastic differentiation stage and is not silenced by DNA methylation in osteosarcoma

scientific article published on 5 January 2015

siRNA specificity searching incorporating mismatch tolerance data

scientific article

siRNAdb: a database of siRNA sequences

scientific article (publication date: 2005)

siRNAdb: a database of siRNA sequences

scientific article

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