Search filters

List of works by Alessandra Mortellaro

A novel human anti-interleukin-1β neutralizing monoclonal antibody showing in vivo efficacy

scientific article

A unique role for p53 in the regulation of M2 macrophage polarization

scientific article

Assessment of thymic output in common variable immunodeficiency patients by evaluation of T cell receptor excision circles

scientific article published on 01 August 2002

C5a Regulates IL-1β Production and Leukocyte Recruitment in a Murine Model of Monosodium Urate Crystal-Induced Peritonitis

scientific article published on 23 January 2017

CD103(+) Dendritic Cells Control Th17 Cell Function in the Lung

scientific article published on 9 September 2015

CD80 and CD86 Differentially Regulate Mechanical Interactions of T-Cells with Antigen-Presenting Dendritic Cells and B-Cells ⬇️

scientific article published on September 14, 2012

Calcineurin B in CD4+ T Cells Prevents Autoimmune Colitis by Negatively Regulating the JAK/STAT Pathway.

scientific article

Calcineurin-mediated IL-2 production by CD11chighMHCII+ myeloid cells is crucial for intestinal immune homeostasis.

scientific article

Calcineurin/NFAT signalling inhibits myeloid haematopoiesis.

scientific article published on 7 February 2012

Caspase-11: the driving factor for noncanonical inflammasomes

scientific article published on September 2013

Continuous time Bayesian networks identify Prdm1 as a negative regulator of TH17 cell differentiation in humans

scientific article published on 15 March 2016

Correction of ADA-SCID by stem cell gene therapy combined with nonmyeloablative conditioning

scientific article published in June 2002

Cutting edge: the NLRP3 inflammasome links complement-mediated inflammation and IL-1β release.

scientific article published on July 2013

E3 Ubiquitin ligase ZNRF4 negatively regulates NOD2 signalling and induces tolerance to MDP.

scientific article

Erratum: E3 Ubiquitin ligase ZNRF4 negatively regulates NOD2 signalling and induces tolerance to MDP.

scientific article published on 18 August 2017

Ex vivo gene therapy with lentiviral vectors rescues adenosine deaminase (ADA)-deficient mice and corrects their immune and metabolic defects

scientific article published on 11 July 2006

From vaccine practice to vaccine science: the contribution of human immunology to the prevention of infectious disease ⬇️

scientific article published on 08 February 2011

GM-CSF-licensed CD11b+ lung dendritic cells orchestrate Th2 immunity to Blomia tropicalis.

scientific article published on 18 June 2014

Genome-wide analysis of the genetic regulation of gene expression in human neutrophils

scientific article published on 10 August 2015

Human caspase-4 and caspase-5 regulate the one-step non-canonical inflammasome activation in monocytes

scientific article

Immune reconstitution in ADA-SCID after PBL gene therapy and discontinuation of enzyme replacement

scientific article published in May 2002

Inflammasome-dependent IL-1β release depends upon membrane permeabilisation

scientific article

Inhibition of NLRP3 inflammasome activation by cell-permeable stapled peptides

scientific article published on 20 March 2019

Investigating IL-1β Secretion Using Real-Time Single-Cell Imaging.

scientific article

Mechanical interactions between dendritic cells and T cells correlate with T cell responsiveness

scientific article published on 27 May 2011

NLRC4 gets out of control

scientific article published on 01 October 2014

NLRP10 Enhances CD4+ T-Cell-Mediated IFNγ Response via Regulation of Dendritic Cell-Derived IL-12 Release

scientific article published on 2 November 2017

NLRP3 inflammasome pathway has a critical role in the host immunity against clinically relevant Acinetobacter baumannii pulmonary infection

scientific article published on 14 June 2017

NLRPs, microbiota, and gut homeostasis: unravelling the connection.

scientific article

Nod2 is required for the early innate immune clearance of Acinetobacter baumannii from the lungs.

scientific article published on 12 December 2017

Probing host pathogen cross-talk by transcriptional profiling of both Mycobacterium tuberculosis and infected human dendritic cells and macrophages

scientific article

Salmonella typhimurium-induced IL-1 release from primary human monocytes requires NLRP3 and can occur in the absence of pyroptosis.

scientific article

Spotlight on Mycobacteria and dendritic cells: will novel targets to fight tuberculosis emerge?

scientific article published on April 2009

Synergism between curdlan and GM-CSF confers a strong inflammatory signature to dendritic cells.

scientific article published on 16 January 2012

Synergism of NOD2 and NLRP3 activators promotes a unique transcriptional profile in murine dendritic cells.

scientific article published on 30 September 2010

The Inflammasome Adaptor ASC Intrinsically Limits CD4+ T-Cell Proliferation to Help Maintain Intestinal Homeostasis

scientific article published on 15 July 2019

The NLRP3 Inflammasome May Contribute to Pathologic Neovascularization in the Advanced Stages of Diabetic Retinopathy.

scientific article published on 12 February 2018

The NLRP3 inflammasome affects DNA damage responses after oxidative and genotoxic stress in dendritic cells

scientific article published on 24 May 2013

The Nod1, Nod2, and Rip2 axis contributes to host immune defense against intracellular Acinetobacter baumannii infection

scientific article

The Syk-NFAT-IL-2 Pathway in Dendritic Cells Is Required for Optimal Sterile Immunity Elicited by Alum Adjuvants

scientific article published on 28 November 2016

The controversial relationship between NLRP3, alum, danger signals and the next-generation adjuvants.

scientific article published on March 2010

The inflammasomes in health and disease: from genetics to molecular mechanisms of autoinflammation and beyond ⬇️

scientific article published on January 24, 2011

The need to identify myeloid dendritic cell progenitors in human blood.

scientific article published on 14 October 2009

The rhapsody of NLRPs: master players of inflammation...and a lot more

scientific article published on September 2012

Tyrosine Dephosphorylation of ASC Modulates the Activation of the NLRP3 and AIM2 Inflammasomes

scientific article published on 05 July 2019

Tyrosine kinases: the molecular switch for inflammasome activation

scientific article published on 10 February 2014

Paulina is supported by:

About Paulina

Help