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List of works by Christoph Engel

19p13.1 is a triple-negative-specific breast cancer susceptibility locus

scientific article published on 13 February 2012

A BRCA1 promoter variant (rs11655505) and breast cancer risk

scientific article published in April 2010

A biomathematical model of human erythropoiesis under erythropoietin and chemotherapy administration

scientific article

A breast cancer risk haplotype in the caspase-8 gene

scientific article published on 24 March 2009

A classification model for BRCA2 DNA binding domain missense variants based on homology-directed repair activity

scientific article published on 29 October 2012

A combined approach to generate laboratory reference intervals using unbalanced longitudinal data

scientific article

A combined model of human erythropoiesis and granulopoiesis under growth factor and chemotherapy treatment

scientific article

A computational model of human granulopoiesis to simulate the hematotoxic effects of multicycle polychemotherapy

scientific article published on 29 June 2004

A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population

scientific article

A multicenter randomized controlled study of an extracorporeal cytokine hemoadsorption device in septic patients.

scientific article published on 19 March 2013

A pharmacokinetic model of filgrastim and pegfilgrastim application in normal mice and those with cyclophosphamide-induced granulocytopaenia

scientific article published on 17 August 2009

A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer

scientific article published on 18 June 2018

APOE e4-Genotype and Lifestyle Interaction on Cognitive Performance: Results of the LIFE-Adult-Study

scientific article published on 7 December 2017

AURKA F31I polymorphism and breast cancer risk in BRCA1 and BRCA2 mutation carriers: a consortium of investigators of modifiers of BRCA1/2 study

scientific article published on July 2007

Absence of association between cyclin D1 (CCND1) G870A polymorphism and age of onset in hereditary nonpolyposis colorectal cancer

scientific article published on 01 May 2006

Activating ERBB2/HER2 mutations indicate susceptibility to pan-HER inhibitors in Lynch and Lynch-like colorectal cancer

scientific article

Acute hematologic toxicity and practicability of dose-intensified BEACOPP chemotherapy for advanced stage Hodgkin's disease. German Hodgkin's Lymphoma Study Group (GHSG).

scientific article

Acute renal failure in patients with severe sepsis and septic shock--a significant independent risk factor for mortality: results from the German Prevalence Study

scientific article published on 7 December 2007

Age, ocular magnification, and circumpapillary retinal nerve fiber layer thickness

scientific article published in December 2017

Age- and gender-specific norms for the German version of the Three-Factor Eating-Questionnaire (TFEQ).

scientific article published on 15 April 2015

Age-, sex-, and education-specific norms for an extended CERAD Neuropsychological Assessment Battery-Results from the population-based LIFE-Adult-Study

scientific article published on 8 March 2018

Age-dependent performance of BRAF mutation testing in Lynch syndrome diagnostics

scientific article published on 01 September 2020

Alcohol Consumption, Cigarette Smoking, and Risk of Breast Cancer for BRCA1 and BRCA2 Mutation Carriers: Results from The BRCA1 and BRCA2 Cohort Consortium

scientific article published on 02 December 2019

An evaluation of the polymorphisms Ins16bp and Arg72Pro in p53 as breast cancer risk modifiers in BRCA1 and BRCA2 mutation carriers

scientific article published on September 2008

An original phylogenetic approach identified mitochondrial haplogroup T1a1 as inversely associated with breast cancer risk in BRCA2 mutation carriers

scientific article published on 25 April 2015

Analyte and matrix evaporability - key players of low-temperature plasma ionization for ambient mass spectrometry

scientific article published on 28 June 2018

Are renal adverse effects of hydroxyethyl starches merely a consequence of their incorrect use?

scientific article published on March 2011

Are social conflicts at work associated with depressive symptomatology? Results from the population-based LIFE-Adult-Study

scientific article published on 12 February 2020

Arg462Gln sequence variation in the prostate-cancer-susceptibility gene RNASEL and age of onset of hereditary non-polyposis colorectal cancer: a case-control study

scientific article published on 01 August 2005

Assessing associations between the AURKA-HMMR-TPX2-TUBG1 functional module and breast cancer risk in BRCA1/2 mutation carriers

scientific article

Association Between Loss-of-Function Mutations Within the FANCM Gene and Early-Onset Familial Breast Cancer

scientific article published on 29 December 2016

Association analysis identifies 65 new breast cancer risk loci.

scientific article published on 23 October 2017

Association between TAS2R38 gene polymorphisms and colorectal cancer risk: a case-control study in two independent populations of Caucasian origin

scientific article (publication date: 2011)

Association between echocardiographic parameters and biomarkers in probands with atrial fibrillation and different PR interval lengths: Insight from the epidemiologic LIFE Adult Study

scientific article published on 28 February 2019

Association between mental demands at work and cognitive functioning in the general population - results of the health study of the Leipzig research center for civilization diseases (LIFE).

scientific article

Association of Genomic Domains in BRCA1 and BRCA2 with Prostate Cancer Risk and Aggressiveness

scientific article published on 13 November 2019

Association of breast cancer risk in BRCA1 and BRCA2 mutation carriers with genetic variants showing differential allelic expression: identification of a modifier of breast cancer risk at locus 11q22.3.

scientific article

Association of death receptor 4 variant (683A > C) with ovarian cancer risk in BRCA1 mutation carriers

scientific article

Association of hormone receptor status with grading, age of onset, and tumor size in BRCA1-associated breast cancer

scientific article published on 21 April 2009

Association of the BRCA1 missense variant R1699W with a malignant phyllodes tumor of the breast

scientific article published on July 2007

Association of the variants CASP8 D302H and CASP10 V410I with breast and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers

scientific article

Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer

scientific article

Associations Between Anxiety, Body Mass Index, and Sex Hormones in Women

scientific article published on 04 July 2019

Associations of Pathogenic Variants in MLH1, MSH2, and MSH6 With Risk of Colorectal Adenomas and Tumors and With Somatic Mutations in Patients With Lynch Syndrome

scientific article published on 08 January 2020

Associations of Sex Hormones and Anthropometry with the Speaking Voice Profile in the Adult General Population

scientific article

Associations of common breast cancer susceptibility alleles with risk of breast cancer subtypes in BRCA1 and BRCA2 mutation carriers

scientific article published on 31 December 2014

Associations of obesity and circulating insulin and glucose with breast cancer risk: a Mendelian randomization analysis

article by Xiang Shu et al published 1 October 2018 in International Journal of Epidemiology

Atopic dermatitis is associated with autoimmune but not with cardiovascular comorbidities in a random sample of the general population in Leipzig, Germany.

scientific article

Automatic control of pressure support for ventilator weaning in surgical intensive care patients

scientific article published on 20 January 2012

BRCA1 R1699Q variant displaying ambiguous functional abrogation confers intermediate breast and ovarian cancer risk

scientific article published on August 2012

BRCA1/2 testing: uptake, phenocopies, and strategies to improve detection rates in initially negative families

scientific article published on 19 October 2011

BRIP1 loss-of-function mutations confer high risk for familial ovarian cancer, but not familial breast cancer

scientific article published on 24 January 2018

Biomarker candidates for the detection of an infectious etiology of febrile neutropenia

scientific article published on 15 August 2015

Breast and Prostate Cancer Risks for Male BRCA1 and BRCA2 Pathogenic Variant Carriers Using Polygenic Risk Scores

scientific article published on 11 January 2022

Breast cancer risk in BRCA1/2 mutation carriers and noncarriers under prospective intensified surveillance

scientific article published on 22 May 2019

Breast cancer risks and risk prediction models

scientific article

Cancer Risks Associated With Germline PALB2 Pathogenic Variants: An International Study of 524 Families

scientific article published on 16 December 2019

Cancer Risks for PMS2-Associated Lynch Syndrome

scientific article published on 30 August 2018

Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database

scientific article published on 24 July 2019

Candidate genetic modifiers for breast and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers

scientific article

Clinical practice of fluid resuscitation in severe sepsis and septic shock on German ICUs.

scientific article

Colorectal surveillance in Lynch syndrome families.

scientific article published on June 2013

Common alleles at 6q25.1 and 1p11.2 are associated with breast cancer risk for BRCA1 and BRCA2 mutation carriers

scientific article published on 18 May 2011

Common breast cancer susceptibility alleles and the risk of breast cancer for BRCA1 and BRCA2 mutation carriers: implications for risk prediction

scientific article

Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2.

scientific article published on 2 November 2011

Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers

scientific article

Common variants associated with breast cancer in genome-wide association studies are modifiers of breast cancer risk in BRCA1 and BRCA2 mutation carriers

scientific article

Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriers

scientific article

Common variants at the 19p13.1 and ZNF365 loci are associated with ER subtypes of breast cancer and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers

scientific article published on 20 February 2012

Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers

scientific article published on 05 August 2009

Common variants of the BRCA1 wild-type allele modify the risk of breast cancer in BRCA1 mutation carriers

scientific article

Contralateral breast cancer risk in BRCA1 and BRCA2 mutation carriers

scientific article published on 26 October 2009

Copy number variation analysis and targeted NGS in 77 families with suspected Lynch syndrome reveals novel potential causative genes

scientific article published on 03 October 2018

Correction to: Risk-reducing salpingo-oophorectomy, natural menopause, and breast cancer risk: an international prospective cohort of BRCA1 and BRCA2 mutation carriers

scientific article published on 26 February 2020

Correction: Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database

scientific article published on 20 July 2020

Correspondence (reply): In reply

scientific article published on 01 May 2013

Cost-effectiveness of different strategies to prevent breast and ovarian cancer in German women with a BRCA 1 or 2 mutation

scientific article published on 5 April 2017

Could High Mental Demands at Work Offset the Adverse Association Between Social Isolation and Cognitive Functioning? Results of the Population-Based LIFE-Adult-Study

scientific article

Current practice in nutritional support and its association with mortality in septic patients--results from a national, prospective, multicenter study

scientific article

DNA glycosylases involved in base excision repair may be associated with cancer risk in BRCA1 and BRCA2 mutation carriers

scientific article

DNA methylation array analyses identified breast cancer-associatedHYAL2methylation in peripheral blood

Diagnosis of Li-Fraumeni Syndrome: Differentiating TP53 germline mutations from clonal hematopoiesis: Results of the observational AGO-TR1 trial

scientific article published on 03 October 2018

Discrimination of Head and Neck Squamous Cell Carcinoma Patients and Healthy Adults by 10-Color Flow Cytometry: Development of a Score Based on Leukocyte Subsets

scientific article published on 12 June 2019

Does physiological distribution of blood parameters in children depend on socioeconomic status? Results of a German cross-sectional study

scientific article

Double heterozygosity for mutations in BRCA1 and BRCA2 in German breast cancer patients: implications on test strategies and clinical management

scientific article published on 26 April 2012

Eating Behaviour in the General Population: An Analysis of the Factor Structure of the German Version of the Three-Factor-Eating-Questionnaire (TFEQ) and Its Association with the Body Mass Index

scientific article published on 31 July 2015

Economic modeling of risk-adapted screen-and-treat strategies in women at high risk for breast or ovarian cancer

scientific article published on 21 February 2019

Effect of Empirical Treatment With Moxifloxacin and Meropenem vs Meropenem on Sepsis-Related Organ Dysfunction in Patients With Severe Sepsis ⬇️

scientific article published on June 13, 2012

Effect of Hydrocortisone on Development of Shock Among Patients With Severe Sepsis: The HYPRESS Randomized Clinical Trial

scientific article published on 03 October 2016

Effect of Sodium Selenite Administration and Procalcitonin-Guided Therapy on Mortality in Patients With Severe Sepsis or Septic Shock: A Randomized Clinical Trial

scientific article published on 18 July 2016

Effect of a multifaceted educational intervention for anti-infectious measures on sepsis mortality: a cluster randomized trial

scientific article published on 2 May 2017

Effects of lifestyle intervention in BRCA1/2 mutation carriers on nutrition, BMI, and physical fitness (LIBRE study): study protocol for a randomized controlled trial

scientific article published on 29 July 2016

Effects of psychological eating behaviour domains on the association between socio-economic status and BMI.

scientific article

Efficacy of annual colonoscopic surveillance in individuals with hereditary nonpolyposis colorectal cancer

scientific article published on 14 October 2009

Eight novel MSH6 germline mutations in patients with familial and nonfamilial colorectal cancer selected by loss of protein expression in tumor tissue

scientific article published in March 2004

Endogenous thrombopoietin serum levels during multicycle chemotherapy

scientific article

Epidemiology of sepsis in Germany: results from a national prospective multicenter study

scientific article published on 24 February 2007

Epidemiology of severe sepsis and septic shock in Germany: results from the German 'Prevalence' study.

scientific article published on 7 March 2005

Evaluating the performance of clinical criteria for predicting mismatch repair gene mutations in Lynch syndrome: A comprehensive analysis of 3,671 families

article

Evaluating the performance of the breast cancer genetic risk models BOADICEA, IBIS, BRCAPRO and Claus for predicting BRCA1/2 mutation carrier probabilities: a study based on 7352 families from the German Hereditary Breast and Ovarian Cancer Consorti

scientific article published on 06 April 2013

Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers

scientific article

Evaluation of a candidate breast cancer associated SNP in ERCC4 as a risk modifier in BRCA1 and BRCA2 mutation carriers. Results from the Consortium of Investigators of Modifiers of BRCA1/BRCA2 (CIMBA).

scientific article

Evidence for SMAD3 as a modifier of breast cancer risk in BRCA2 mutation carriers

scientific article

Expanded extracolonic tumor spectrum in MUTYH-associated polyposis

scientific article

External ventricular drain infections: risk factors and outcome.

scientific article published on 17 November 2014

FHL2 expression in peritumoural fibroblasts correlates with lymphatic metastasis in sporadic but not in HNPCC-associated colon cancer

scientific article

Fatigue in Cancer and Neuroinflammatory and Autoimmune Disease: CNS Arousal Matters

scientific article published on 19 August 2020

Fatty acid profiles in erythrocyte membranes following the Mediterranean diet - data from a multicenter lifestyle intervention study in women with hereditary breast cancer (LIBRE)

scientific article published on 02 November 2019

Feasibility of structured endurance training and Mediterranean diet in BRCA1 and BRCA2 mutation carriers - an interventional randomized controlled multicenter trial (LIBRE-1).

scientific article

Fine-mapping of 150 breast cancer risk regions identifies 178 high confidence target genes

article

Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes

scientific article published on 07 January 2020

Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1.

scientific article

Fluid therapy in severe sepsis: results from a representative survey of German ICUs

scientific article published on 11 November 2009

Functional annotation of the 2q35 breast cancer risk locus implicates a structural variant in influencing activity of a long-range enhancer element

scientific article published in July 2021

Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus

scientific article published on 7 September 2016

Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers

scientific article published on 27 March 2013

Gene Polymorphisms in the Heme Degradation Pathway and Outcome of Severe Human Sepsis

scientific article published on 01 November 2012

Gene panel testing of 5589 BRCA1/2-negative index patients with breast cancer in a routine diagnostic setting: results of the German Consortium for Hereditary Breast and Ovarian Cancer

scientific article published on 9 March 2018

Genome-wide analysis associates familial colorectal cancer with increases in copy number variations and a rare structural variation at 12p12.3.

scientific article published on 14 October 2013

Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer

article

Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk

scientific article (publication date: 2013)

Genome-wide association study of germline variants and breast cancer-specific mortality

scientific article published on 21 February 2019

Genomic and transcriptomic heterogeneity of colorectal tumors arising in Lynch Syndrome

scientific article published on 20 July 2017

Genomic rearrangements in MSH2, MLH1 or MSH6 are rare in HNPCC patients carrying point mutations

scientific article published on 11 July 2006

Genotype-phenotype comparison of German MLH1 and MSH2 mutation carriers clinically affected with Lynch syndrome: a report by the German HNPCC Consortium

scientific article published on 14 August 2006

Germline Mutations in Triple-Negative Breast Cancer

scientific article

Germline loss-of-function variants in the BARD1 gene are associated with early-onset familial breast cancer but not ovarian cancer

scientific article published on 29 April 2019

Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene

scientific article

Guidelines for the clinical management of Lynch syndrome (hereditary non-polyposis cancer).

scientific article published on 27 February 2007

Guidelines for the clinical management of familial adenomatous polyposis (FAP).

scientific article published on 14 January 2008

HLA Class II Allele Analyses Implicate Common Genetic Components in Type 1 and Non-Insulin-Treated Type 2 Diabetes

scientific article published on 01 March 2020

HNPCC-associated small bowel cancer: clinical and molecular characteristics

scientific article published on 01 March 2005

Height and Body Mass Index as Modifiers of Breast Cancer Risk in BRCA1/2 Mutation Carriers: A Mendelian Randomization Study

scientific article published on 01 April 2019

Hemodynamic monitoring in severe sepsis and septic shock in German ICUs.

scientific article

Hemotoxicity by prolonged etoposide administration to mice can be prevented by simultaneous growth factor therapy.

scientific article published on January 1995

Hereditary nonpolyposis colorectal cancer (HNPCC)/Lynch syndrome

scientific article

High-risk breast cancer surveillance with MRI: 10-year experience from the German consortium for hereditary breast and ovarian cancer

scientific article published on 06 February 2019

Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

scientific article

Identification of a DMBT1 polymorphism associated with increased breast cancer risk and decreased promoter activity

scientific article

Identification of six new susceptibility loci for invasive epithelial ovarian cancer

scientific article published on 12 January 2015

Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer

scientific article published on 23 October 2017

Impact of compliance with infection management guidelines on outcome in patients with severe sepsis: a prospective observational multi-center study

scientific article

In vivo effects of interleukin-11 and stem cell factor in combination with erythropoietin in the regulation of erythropoiesis

scientific article published on 01 August 1995

Increased estrogen level can be associated with depression in males

scientific article

Incremental value of Veterans Specific Activity Questionnaire and the YMCA-step test for the assessment of cardiorespiratory fitness in population-based studies

scientific article

Intensive insulin therapy and pentastarch resuscitation in severe sepsis

scientific article

Interactions of erythropoietin, granulocyte colony-stimulating factor, stem cell factor, and interleukin-11 on murine hematopoiesis during simultaneous administration ⬇️

scientific article published on May 1, 1998

Investigating the effects of additional truncating variants in DNA-repair genes on breast cancer risk in BRCA1-positive women

scientific article published on 08 August 2019

Lack of association between screening interval and cancer stage in Lynch syndrome may be accounted for by over-diagnosis; a prospective Lynch syndrome database report

scientific article published on 28 February 2019

Large scale multifactorial likelihood quantitative analysis of BRCA1 and BRCA2 variants: An ENIGMA resource to support clinical variant classification

scientific article published on 01 September 2019

Lifestyle intervention in BRCA1/2 mutation carriers: study protocol for a prospective, randomized, controlled clinical feasibility trial (LIBRE-1 study).

scientific article published on 19 December 2016

Living in the city centre is associated with type 1 sensitization to outdoor allergens in Leipzig, Germany

scientific article published on 25 October 2018

Low-risk variants FGFR2, TNRC9 and LSP1 in German familial breast cancer patients

scientific article published in June 2010

Lower incidence of colorectal cancer and later age of disease onset in 27 families with pathogenic MSH6 germline mutations compared with families with MLH1 or MSH2 mutations: the German Hereditary Nonpolyposis Colorectal Cancer Consortium

scientific article published on 13 October 2004

MAPK pathway inhibitors rescue lethal phenotypes in a BRAF gain-of-function Drosophila melanogaster model.

scientific article published on 30 December 2017

Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2.

scientific article

Managing incidental findings and disclosure of results in a paediatric research cohort - the LIFE Child Study cohort

Memory-related subjective cognitive symptoms in the adult population: prevalence and associated factors - results of the LIFE-Adult-Study.

scientific article

Mendelian randomisation study of height and body mass index as modifiers of ovarian cancer risk in 22,588 BRCA1 and BRCA2 mutation carriers

scientific article published on 19 June 2019

Mendelian randomisation study of smoking exposure in relation to breast cancer risk

scientific article published in October 2021

Missense variants in hMLH1 identified in patients from the German HNPCC consortium and functional studies

scientific article published in June 2011

Model-based design of chemotherapeutic regimens that account for heterogeneity in leucopoenia

scientific article published in March 2006

Model-based optimization of G-CSF treatment during cytotoxic chemotherapy

scientific article

Modelling chemotherapy effects on granulopoiesis

scientific article

Modelling human granulopoiesis under poly-chemotherapy with G-CSF support

scientific article published on 20 December 2004

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

scientific article published on April 2013

Mutational Spectrum in a Worldwide Study of 29,700 Families with BRCA1 or BRCA2 Mutations

scientific article published on 15 February 2018

Mutual inhibition of murine erythropoiesis and granulopoiesis during combined erythropoietin, granulocyte colony-stimulating factor, and stem cell factor administration: in vivo interactions and dose-response surfaces

scientific article published on 01 December 1994

N-Acetyltransferase (NAT) 2 acetylator status and age of tumour onset in patients with sporadic and familial, microsatellite stable (MSS) colorectal cancer

scientific article published on 02 August 2006

N-acetyltransferase (NAT) 2 acetylator status and age of onset in patients with hereditary nonpolyposis colorectal cancer (HNPCC).

scientific article published on 6 December 2005

Neck circumference is similarly predicting for impairment of glucose tolerance as classic anthropometric parameters among healthy and obese children and adolescents

scientific article published on 10 May 2017

New MRI Criteria for Successful Vaginal Breech Delivery in Primiparae.

scientific article

No Difference in Colorectal Cancer Incidence or Stage at Detection by Colonoscopy Among 3 Countries With Different Lynch Syndrome Surveillance Policies

scientific article published on 29 July 2018

No association between MUTYH and MSH6 germline mutations in 64 HNPCC patients

scientific article published on 27 February 2008

No association of TGFB1 L10P genotypes and breast cancer risk in BRCA1 and BRCA2 mutation carriers: a multi-center cohort study

scientific article published on 04 June 2008

No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer.

scientific article published in May 2015

Novel Anthropometry Based on 3D-Bodyscans Applied to a Large Population Based Cohort

scientific article

Novel strategy for optimal sequential application of clinical criteria, immunohistochemistry and microsatellite analysis in the diagnosis of hereditary nonpolyposis colorectal cancer

scientific article published on 01 January 2006

Olfactory dysfunction: properties of the Sniffin' Sticks Screening 12 test and associations with quality of life

scientific article published on 20 November 2018

Olfactory function is associated with cognitive performance: results from the population-based LIFE-Adult-Study

scientific article published on 10 May 2019

Oral Contraceptive Use and Breast Cancer Risk: Retrospective and Prospective Analyses From a BRCA1 and BRCA2 Mutation Carrier Cohort Study

scientific article published on 01 April 2018

Ovarian and breast cancer risks associated with pathogenic variants in RAD51C and RAD51D

scientific article published on 28 February 2020

Ovarian cancer susceptibility alleles and risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers

scientific article

PAIN OUT: an international acute pain registry supporting clinicians in decision making and in quality improvement activities.

scientific article

PROGRESS - prospective observational study on hospitalized community acquired pneumonia

scientific article published on 28 July 2016

Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)

scientific article published on 5 December 2011

Patients' perception of postoperative pain management: validation of the International Pain Outcomes (IPO) questionnaire

scientific article published on 7 September 2013

Performance of in silico prediction tools for the classification of rare BRCA1/2 missense variants in clinical diagnostics.

scientific article published on 27 March 2018

Pharmacokinetic and -dynamic modelling of G-CSF derivatives in humans

scientific article

Pharmacokinetic and pharmacodynamic modelling of the novel human granulocyte colony-stimulating factor derivative Maxy-G34 and pegfilgrastim in rats

scientific article published on 24 September 2009

Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes

scientific article

Polymorphisms in BRCA2 resulting in aberrant codon-usage and their analysis on familial breast cancer risk

scientific article

Polymorphisms in a Putative Enhancer at the 10q21.2 Breast Cancer Risk Locus Regulate NRBF2 Expression

scientific article published on 11 June 2015

Polymorphisms of genes coding for ghrelin and its receptor in relation to colorectal cancer risk: a two-step gene-wide case-control study

scientific article

Practice and perception--a nationwide survey of therapy habits in sepsis

scientific article

Practice of volume therapy in patients with severe sepsis: results from a nationwide sepsis prevalence study

scientific article published on 02 December 2009

Prediction of Breast and Prostate Cancer Risks in Male BRCA1 and BRCA2 Mutation Carriers Using Polygenic Risk Scores

scientific article

Prevalence and risk factors of smell dysfunction - a comparison between five German population-based studies

scientific article published on 01 April 2020

Prevalence of BRCA1/2 germline mutations in 21 401 families with breast and ovarian cancer

scientific article

Prevalence of Cancer Predisposition Germline Variants in Male Breast Cancer Patients: Results of the German Consortium for Hereditary Breast and Ovarian Cancer

scientific article published on 05 July 2022

Prevalence of DSM-5 Mild Neurocognitive Disorder in Dementia-Free Older Adults: Results of the Population-Based LIFE-Adult-Study

scientific article published on 7 July 2016

Prevalence of moderately increased albuminuria among individuals with normal HbA1c level but impaired glucose tolerance: Results from the LIFE-Adult-Study

scientific article published on 11 July 2018

Prevalence of pathogenic BRCA1/2 germline mutations among 802 women with unilateral triple-negative breast cancer without family cancer history

scientific article published on 7 March 2018

Prophylactic pretreatment of mice with hematopoietic growth factors induces expansion of primitive cell compartments and results in protection against 5-fluorouracil-induced toxicity

scientific article published on 01 June 1996

RAD51 135G-->C modifies breast cancer risk among BRCA2 mutation carriers: results from a combined analysis of 19 studies

scientific article published on 16 October 2007

Recommendations to improve identification of hereditary and familial colorectal cancer in Europe.

scientific article published on 18 September 2009

Reference intervals for leukocyte subsets in adults: Results from a population-based study using 10-color flow cytometry

scientific article published on 29 April 2015

Refined histopathological predictors of BRCA1 and BRCA2 mutation status: a large-scale analysis of breast cancer characteristics from the BCAC, CIMBA, and ENIGMA consortia

scientific article

Relations between sleep duration with overweight and academic stress-just a matter of the socioeconomic status?

scientific article published on 16 January 2019

Reply to V. Bonadona et al ⬇️

scientific article published on June 10, 2013

Revised guidelines for the clinical management of Lynch syndrome (HNPCC): recommendations by a group of European experts

scientific article published on 13 February 2013

Risk-Reducing Gynecological Surgery in Lynch Syndrome: Results of an International Survey from the Prospective Lynch Syndrome Database

scientific article published on 18 July 2020

Risk-reducing salpingo-oophorectomy, natural menopause, and breast cancer risk: an international prospective cohort of BRCA1 and BRCA2 mutation carriers

scientific article published on 16 January 2020

Risks of Breast, Ovarian, and Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers

scientific article published on June 2017

Risks of less common cancers in proven mutation carriers with lynch syndrome

scientific article published on 22 October 2012

Safety of tunneled central venous catheters in pediatric hematopoietic stem cell recipients with severe primary immunodeficiency diseases

scientific article published on 15 May 2020

Screening in women at elevated risk for breast cancer

scientific article published on 20 September 2010

Sepsis survivors monitoring and coordination in outpatient health care (SMOOTH): study protocol for a randomized controlled trial

scientific article

Sex-Specific Differences in Circumpapillary Retinal Nerve Fiber Layer Thickness

scientific article published on 25 September 2019

Sleep quality in the general population: psychometric properties of the Pittsburgh Sleep Quality Index, derived from a German community sample of 9284 people

scientific article published on 4 May 2016

Small bowel cancer risk in Lynch syndrome

scientific article published on 01 November 2008

Smoking and physical inactivity increase cancer prevalence in BRCA-1 and BRCA-2 mutation carriers: results from a retrospective observational analysis.

scientific article published on 3 October 2017

Speaking Voice in Children and Adolescents: Normative Data and Associations with BMI, Tanner Stage, and Singing Activity

scientific article published on 25 May 2018

Spectrum and frequencies of mutations in MSH2 and MLH1 identified in 1,721 German families suspected of hereditary nonpolyposis colorectal cancer

scientific article published on 01 September 2005

Standardization and Feasibility of Voice Range Profile Measurements in Epidemiological Studies

scientific article published on 10 May 2020

Study protocol of the VISEP study. Response of the SepNet study group

scientific article published in July 2008

Systemic and Ocular Determinants of Peripapillary Retinal Nerve Fiber Layer Thickness Measurements in the European Eye Epidemiology (E3) Population

article by Matthias M. Mauschitz et al published October 2018 in Ophthalmology

Targeted On-line SPE-LC-MS/MS Assay for the Quantitation of 12 Apolipoproteins from Human Blood

scientific article published on 26 December 2017

Targeting of heme oxygenase-1 as a novel immune regulator of neuroblastoma

scientific article published on 23 November 2015

Ten recently identified associations between nsSNPs and colorectal cancer could not be replicated in German families

article

Testosterone imbalance may link depression and increased body weight in premenopausal women.

scientific article

The "unnatural" history of colorectal cancer in Lynch syndrome: lessons from colonoscopy surveillance

scientific article published on 19 July 2020

The Apparent Genetic Anticipation in PMS2-Associated Lynch Syndrome Families Is Explained by Birth-cohort Effect

scientific article published on 01 March 2019

The BRCA1 c. 5096G>A p.Arg1699Gln (R1699Q) intermediate risk variant: breast and ovarian cancer risk estimation and recommendations for clinical management from the ENIGMA consortium

scientific article published on 10 May 2017

The GPRC5A frameshift variant c.183del is not associated with increased breast cancer risk in BRCA1 mutation carriers

scientific article published on 06 January 2019

The Influence of Number and Timing of Pregnancies on Breast Cancer Risk for Women With or Mutations

The LIFE-Adult-Study: objectives and design of a population-based cohort study with 10,000 deeply phenotyped adults in Germany

scientific article

The Prevalence of Current Depressive Symptoms in an Urban Adult Population

scientific article

The Speaking Voice in the General Population: Normative Data and Associations to Sociodemographic and Lifestyle Factors

scientific article

The TP53 Arg72Pro and MDM2 309G>T polymorphisms are not associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers

scientific article published on 25 August 2009

The additive effect of p53 Arg72Pro and RNASEL Arg462Gln genotypes on age of disease onset in Lynch syndrome patients with pathogenic germline mutations in MSH2 or MLH1

scientific article published on 16 January 2007

The association between mental demands at the workplace and cognitive functioning: the role of the big five personality traits

scientific article published on 25 May 2019

The association between unemployment and depression-Results from the population-based LIFE-adult-study

scientific article published on 10 April 2018

The budgetary impact of genetic testing for hereditary breast cancer for the statutory health insurance

scientific article published on 09 September 2019

The effect of Ginkgo biloba extract (EGb 761) on parameters of oxidative stress in different regions of aging rat brains after acute hypoxia

scientific article published on 27 August 2010

The effect of a novel extracorporeal cytokine hemoadsorption device on IL-6 elimination in septic patients: A randomized controlled trial

scientific article published on 30 October 2017

The kinetics of murine hematopoietic stem cells in vivo in response to prolonged increased mature blood cell production induced by granulocyte colony-stimulating factor

scientific article published on 01 October 1995

The p53 codon 72 variation is associated with the age of onset of hereditary non-polyposis colorectal cancer (HNPCC)

scientific article

The risk of contralateral breast cancer in patients from BRCA1/2 negative high risk families as compared to patients from BRCA1 or BRCA2 positive families: a retrospective cohort study

scientific article

The role of HPV RNA transcription, immune response-related gene expression and disruptive TP53 mutations in diagnostic and prognostic profiling of head and neck cancer.

scientific article published on 20 June 2015

Transcriptome-wide association study of breast cancer risk by estrogen-receptor status

scientific article published on 01 March 2020

Uncovering the Contribution of Moderate-Penetrance Susceptibility Genes to Breast Cancer by Whole-Exome Sequencing and Targeted Enrichment Sequencing of Candidate Genes in Women of European Ancestry

scientific article published on 11 July 2022

Validation of a brief step-test protocol for estimation of peak oxygen uptake

scientific article published on 29 April 2014

Validation of the German version of the Mediterranean Diet Adherence Screener (MEDAS) questionnaire

scientific article

Validation of the Manchester scoring system for predicting BRCA1/2 mutations in 9,390 families suspected of having hereditary breast and ovarian cancer

scientific article published on 25 April 2014

Value of upper GI endoscopy for gastric cancer surveillance in patients with Lynch syndrome

scientific article published on 15 September 2020

Variability of structures in German intensive care units--a representative, nationwide analysis

scientific article published on 27 September 2010

Ventilatory strategies in septic patients. Results from a nationwide observational trial

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[Current recommendations for surveillance, risk reduction and therapy in Lynch syndrome patients]

scientific article published on 18 November 2019

[Gender-Specific Differences in the Utilization of Health Care Services in an Urban Population Sample]

scientific article published on 15 March 2019

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