List of works - María Llorens-Martín

A new cerebellar neuron: the brush or monopolar cell. Characteristics and possible function

scientific article published in February 2004

Absence of CX3CR1 impairs the internalization of Tau by microglia.

scientific article published on 15 August 2017

Absence of microglial CX3CR1 impairs the synaptic integration of adult-born hippocampal granule neurons

scientific article

Activity-Dependent Reconnection of Adult-Born Dentate Granule Cells in a Mouse Model of Frontotemporal Dementia

scientific article published on 27 May 2019

Adult hippocampal neurogenesis is abundant in neurologically healthy subjects and drops sharply in patients with Alzheimer's disease

scientific article published on 25 March 2019

Adult-born neurons in brain circuitry

scientific article published on 01 May 2019

Alzheimer disease-like cellular phenotype of newborn granule neurons can be reversed in GSK-3β-overexpressing mice.

scientific article

Anti-IL17 treatment ameliorates Down syndrome phenotypes in mice

scientific article published on 31 May 2018

Antidepressant and proneurogenic influence of environmental enrichment in mice: protective effects vs recovery.

scientific article

Blockade of insulin-like growth factor-I has complex effects on structural plasticity in the hippocampus.

scientific article published on June 2010

Both increases in immature dentate neuron number and decreases of immobility time in the forced swim test occurred in parallel after environmental enrichment of mice.

scientific article published on 14 June 2007

Central actions of liver-derived insulin-like growth factor I underlying its pro-cognitive effects

scientific article published on 11 September 2007

Cessation of voluntary wheel running increases anxiety-like behavior and impairs adult hippocampal neurogenesis in mice.

scientific article

Cognitive Decline in Neuronal Aging and Alzheimer's Disease: Role of NMDA Receptors and Associated Proteins.

scientific article published on 10 November 2017

Different susceptibility to neurodegeneration of dorsal and ventral hippocampal dentate gyrus: a study with transgenic mice overexpressing GSK3β.

scientific article

Differential regulation of the variations induced by environmental richness in adult neurogenesis as a function of time: a dual birthdating analysis

scientific article

Direct Evidence of Internalization of Tau by Microglia In Vitro and In Vivo.

scientific article published on 28 November 2015

Dual effects of increased glycogen synthase kinase-3β activity on adult neurogenesis

scientific article

Effects of voluntary physical exercise on adult hippocampal neurogenesis and behavior of Ts65Dn mice, a model of Down syndrome.

scientific article published on 26 September 2010

Exercise modulates insulin-like growth factor 1-dependent and -independent effects on adult hippocampal neurogenesis and behaviour.

scientific article

Exercising New Neurons to Vanquish Alzheimer Disease

scientific article published on 12 December 2018

Expression of frontotemporal dementia with parkinsonism associated to chromosome 17 tau induces specific degeneration of the ventral dentate gyrus and depressive-like behavior in mice.

scientific article published on 27 August 2011

Forced swimming sabotages the morphological and synaptic maturation of newborn granule neurons and triggers a unique pro-inflammatory milieu in the hippocampus

scientific article published on 24 December 2015

GSK-3β Overexpression Alters the Dendritic Spines of Developmentally Generated Granule Neurons in the Mouse Hippocampal Dentate Gyrus

scientific article published on 10 March 2017

GSK-3β overexpression causes reversible alterations on postsynaptic densities and dendritic morphology of hippocampal granule neurons in vivo.

scientific article published on 12 February 2013

GSK-3β, a pivotal kinase in Alzheimer disease.

scientific article

GSK3β Overexpression in Dentate Gyrus Neural Precursor Cells Expands the Progenitor Pool and Enhances Memory Skills.

scientific article

GSK3β is involved in the relief of mitochondria pausing in a Tau-dependent manner

scientific article

Inhibition of adult hippocampal neurogenesis disrupts contextual learning but spares spatial working memory, long-term conditional rule retention and spatial reversal.

scientific article published on 16 December 2008

Looking for novel functions of tau.

scientific article published on August 2012

Maturation Dynamics of the Axon Initial Segment (AIS) of Newborn Dentate Granule Cells in Young Adult C57BL/6J Mice

scientific article published on 16 January 2019

Memantine normalizes several phenotypic features in the Ts65Dn mouse model of Down syndrome.

scientific article published in January 2010

Mifepristone prevents stress-induced apoptosis in newborn neurons and increases AMPA receptor expression in the dentate gyrus of C57/BL6 mice

scientific article

Multiple birthdating analyses in adult neurogenesis: a line-up of the usual suspects.

scientific article published on 27 May 2011

New Beginnings in Alzheimer's Disease: The Most Prevalent Tauopathy.

scientific article published on 16 March 2018

Novel connection between newborn granule neurons and the hippocampal CA2 field

scientific article published on November 2014

Novel function of Tau in regulating the effects of external stimuli on adult hippocampal neurogenesis

scientific article

Peripherally triggered and GSK-3β-driven brain inflammation differentially skew adult hippocampal neurogenesis, behavioral pattern separation and microglial activation in response to ibuprofen.

scientific article

Retroviral induction of GSK-3β expression blocks the stimulatory action of physical exercise on the maturation of newborn neurons.

scientific article

Role of neuroinflammation in adult neurogenesis and Alzheimer disease: therapeutic approaches

scientific article published on 3 April 2013

Selective alterations of neurons and circuits related to early memory loss in Alzheimer's disease.

scientific article

Soluble Tau has devastating effects on the structural plasticity of hippocampal granule neurons.

scientific article

Spared place and object-place learning but limited spatial working memory capacity in rats with selective lesions of the dentate gyrus

scientific article

Tau Protein and Adult Hippocampal Neurogenesis ⬇️

scientific article published on 09 July 2012

Tau isoform with three microtubule binding domains is a marker of new axons generated from the subgranular zone in the hippocampal dentate gyrus: implications for Alzheimer's disease.

scientific article

The Ever-Changing Morphology of Hippocampal Granule Neurons in Physiology and Pathology

scientific article

The Role of Microglia in the Spread of Tau: Relevance for Tauopathies

scientific article published on 10 July 2018

The Social Component of Environmental Enrichment Is a Pro-neurogenic Stimulus in Adult c57BL6 Female Mice

scientific article published on 26 April 2019

Unraveling human adult hippocampal neurogenesis

scientific article published on 08 January 2020

Untold New Beginnings: Adult Hippocampal Neurogenesis and Alzheimer's Disease.

scientific article published on 16 March 2018

Versatile use of rtTA-expressing retroviruses in the study of neurodegeneration.

scientific article published on 30 December 2016

List of works by María Llorens-Martín

A new cerebellar neuron: the brush or monopolar cell. Characteristics and possible function

Absence of CX3CR1 impairs the internalization of Tau by microglia.

Absence of microglial CX3CR1 impairs the synaptic integration of adult-born hippocampal granule neurons

Activity-Dependent Reconnection of Adult-Born Dentate Granule Cells in a Mouse Model of Frontotemporal Dementia

Adult hippocampal neurogenesis is abundant in neurologically healthy subjects and drops sharply in patients with Alzheimer's disease

Adult-born neurons in brain circuitry

Alzheimer disease-like cellular phenotype of newborn granule neurons can be reversed in GSK-3β-overexpressing mice.

Anti-IL17 treatment ameliorates Down syndrome phenotypes in mice

Antidepressant and proneurogenic influence of environmental enrichment in mice: protective effects vs recovery.

Blockade of insulin-like growth factor-I has complex effects on structural plasticity in the hippocampus.

Both increases in immature dentate neuron number and decreases of immobility time in the forced swim test occurred in parallel after environmental enrichment of mice.

Central actions of liver-derived insulin-like growth factor I underlying its pro-cognitive effects

Cessation of voluntary wheel running increases anxiety-like behavior and impairs adult hippocampal neurogenesis in mice.

Cognitive Decline in Neuronal Aging and Alzheimer's Disease: Role of NMDA Receptors and Associated Proteins.

Different susceptibility to neurodegeneration of dorsal and ventral hippocampal dentate gyrus: a study with transgenic mice overexpressing GSK3β.

Differential regulation of the variations induced by environmental richness in adult neurogenesis as a function of time: a dual birthdating analysis

Direct Evidence of Internalization of Tau by Microglia In Vitro and In Vivo.

Dual effects of increased glycogen synthase kinase-3β activity on adult neurogenesis

Effects of voluntary physical exercise on adult hippocampal neurogenesis and behavior of Ts65Dn mice, a model of Down syndrome.

Exercise modulates insulin-like growth factor 1-dependent and -independent effects on adult hippocampal neurogenesis and behaviour.

Exercising New Neurons to Vanquish Alzheimer Disease

Expression of frontotemporal dementia with parkinsonism associated to chromosome 17 tau induces specific degeneration of the ventral dentate gyrus and depressive-like behavior in mice.

Forced swimming sabotages the morphological and synaptic maturation of newborn granule neurons and triggers a unique pro-inflammatory milieu in the hippocampus

GSK-3β Overexpression Alters the Dendritic Spines of Developmentally Generated Granule Neurons in the Mouse Hippocampal Dentate Gyrus

GSK-3β overexpression causes reversible alterations on postsynaptic densities and dendritic morphology of hippocampal granule neurons in vivo.

GSK-3β, a pivotal kinase in Alzheimer disease.

GSK3β Overexpression in Dentate Gyrus Neural Precursor Cells Expands the Progenitor Pool and Enhances Memory Skills.

GSK3β is involved in the relief of mitochondria pausing in a Tau-dependent manner

Inhibition of adult hippocampal neurogenesis disrupts contextual learning but spares spatial working memory, long-term conditional rule retention and spatial reversal.

Looking for novel functions of tau.

Maturation Dynamics of the Axon Initial Segment (AIS) of Newborn Dentate Granule Cells in Young Adult C57BL/6J Mice

Memantine normalizes several phenotypic features in the Ts65Dn mouse model of Down syndrome.

Mifepristone prevents stress-induced apoptosis in newborn neurons and increases AMPA receptor expression in the dentate gyrus of C57/BL6 mice

Multiple birthdating analyses in adult neurogenesis: a line-up of the usual suspects.

New Beginnings in Alzheimer's Disease: The Most Prevalent Tauopathy.

Novel connection between newborn granule neurons and the hippocampal CA2 field

Novel function of Tau in regulating the effects of external stimuli on adult hippocampal neurogenesis

Peripherally triggered and GSK-3β-driven brain inflammation differentially skew adult hippocampal neurogenesis, behavioral pattern separation and microglial activation in response to ibuprofen.

Retroviral induction of GSK-3β expression blocks the stimulatory action of physical exercise on the maturation of newborn neurons.

Role of neuroinflammation in adult neurogenesis and Alzheimer disease: therapeutic approaches

Selective alterations of neurons and circuits related to early memory loss in Alzheimer's disease.

Soluble Tau has devastating effects on the structural plasticity of hippocampal granule neurons.

Spared place and object-place learning but limited spatial working memory capacity in rats with selective lesions of the dentate gyrus

Tau Protein and Adult Hippocampal Neurogenesis ⬇️

Tau isoform with three microtubule binding domains is a marker of new axons generated from the subgranular zone in the hippocampal dentate gyrus: implications for Alzheimer's disease.

The Ever-Changing Morphology of Hippocampal Granule Neurons in Physiology and Pathology

The Role of Microglia in the Spread of Tau: Relevance for Tauopathies

The Social Component of Environmental Enrichment Is a Pro-neurogenic Stimulus in Adult c57BL6 Female Mice

Unraveling human adult hippocampal neurogenesis

Untold New Beginnings: Adult Hippocampal Neurogenesis and Alzheimer's Disease.

Versatile use of rtTA-expressing retroviruses in the study of neurodegeneration.