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List of works by Eduard Ayuso

Accurate Identification and Quantification of DNA Species by Next-Generation Sequencing in Adeno-Associated Viral Vectors Produced in Insect Cells

scientific article published on 2 May 2017

Accurate Titration of Infectious AAV Particles Requires Measurement of Biologically Active Vector Genomes and Suitable Controls

scientific article published on 27 July 2018

Beta cell expression of IGF-I leads to recovery from type 1 diabetes.

scientific article

Characterization of a recombinant adeno-associated virus type 2 Reference Standard Material

scientific article

Contribution of Intronic miR-338-3p and Its Hosting Gene AATK to Compensatory β-Cell Mass Expansion

scientific article

Endothelial cell transduction in primary cultures from regressing mesonephros.

scientific article

Homologous Recombination Offers Advantages Over Transposition-Based Systems to Generate Recombinant Baculovirus for Adeno-Associated Viral Vector Production

scientific article published on 16 October 2020

Hypothalamic loss of Snord116 recapitulates the hyperphagia of Prader-Willi syndrome.

scientific article published on 29 January 2018

Hypothalamic-specific manipulation of Fto, the ortholog of the human obesity gene FTO, affects food intake in rats.

scientific article

IGF-I mediates regeneration of endocrine pancreas by increasing beta cell replication through cell cycle protein modulation in mice.

scientific article

Identification of miRNAs Involved in Reprogramming Acinar Cells into Insulin Producing Cells

scientific article published on 21 December 2015

In vivo gene transfer to healthy and diabetic canine pancreas.

scientific article published on 5 December 2005

In vivo gene transfer to pancreatic beta cells by systemic delivery of adenoviral vectors.

scientific article published in August 2004

In vivo genetic engineering of murine pancreatic beta cells mediated by single-stranded adeno-associated viral vectors of serotypes 6, 8 and 9.

scientific article published on 11 February 2011

Increased ocular levels of IGF-1 in transgenic mice lead to diabetes-like eye disease.

scientific article published on April 2004

Inducible adeno-associated virus vectors promote functional angiogenesis in adult organisms via regulated vascular endothelial growth factor expression.

scientific article published on 14 May 2009

LRH-1-dependent glucose sensing determines intermediary metabolism in liver

scientific article

Long-Term Efficacy and Safety of Insulin and Glucokinase Gene Therapy for Diabetes: 8-Year Follow-Up in Dogs

scientific article published on 5 April 2017

Manufacturing and characterization of a recombinant adeno-associated virus type 8 reference standard material.

scientific article

Manufacturing of recombinant adeno-associated viral vectors: new technologies are welcome

scientific article published on 06 January 2016

Obesity-associated gene TMEM18 has a role in the central control of appetite and body weight regulation.

scientific article published on 15 August 2017

Operant behavior to obtain palatable food modifies neuronal plasticity in the brain reward circuit.

scientific article

Pancreatic transduction by helper-dependent adenoviral vectors via intraductal delivery.

scientific article published on September 2014

Phagocytosis-shielded lentiviral vectors improve liver gene therapy in nonhuman primates

scientific article published on 01 May 2019

Pharmacology of Recombinant Adeno-associated Virus Production.

scientific article published on 8 January 2018

Practical utilization of recombinant AAV vector reference standards: focus on vector genomes titration by free ITR qPCR.

scientific article published on 30 March 2016

Production, purification and characterization of adeno-associated vectors.

scientific article published on December 2010

Proinsulin slows retinal degeneration and vision loss in the P23H rat model of retinitis pigmentosa

scientific article

Relevance of assembly-activating protein for Adeno-associated virus vector production and capsid protein stability in mammalian and insect cells

scientific article published on 2 August 2017

Single-Stranded DNA Virus Sequencing (SSV-Seq) for Characterization of Residual DNA and AAV Vector Genomes

scientific article published on 01 January 2019

Skeletal muscle metabolism in the pathology and treatment of type 1 diabetes.

scientific article published on January 2010

Stability of the adeno-associated virus 8 reference standard material

scientific article published on 29 March 2019

Telomerase expression confers cardioprotection in the adult mouse heart after acute myocardial infarction

scientific article published on 18 December 2014

Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer

scientific article

The SSV-Seq 2.0 PCR-free method improves the sequencing of adeno-associated viral vector genomes containing GC-rich regions and homopolymers

scientific article published on 16 October 2020

Treatment of diabetes and long-term survival after insulin and glucokinase gene therapy.

scientific article

Twelfth Annual Meeting of the French Society of Cell and Gene Therapy

scientific article published in July 2016

Vascular endothelial growth factor-mediated islet hypervascularization and inflammation contribute to progressive reduction of β-cell mass.

scientific article published on 6 September 2012

Vasculogenesis and angiogenesis in the subcardinal venous plexus of quail mesonephros: spatial and temporal morphological analysis

scientific article published on 01 January 2002

Whole body correction of mucopolysaccharidosis IIIA by intracerebrospinal fluid gene therapy

scientific article