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List of works by Mamoru Hyodo

3',5'-cyclic diguanylic acid reduces the virulence of biofilm-forming Staphylococcus aureus strains in a mouse model of mastitis infection

scientific article

A comparative study between nanoparticle-targeted therapeutics and bioconjugates as obesity medication.

scientific article published on 18 July 2013

A cyclic-di-GMP receptor required for bacterial exopolysaccharide production

scientific article

A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP

scientific article

A pH-sensitive cationic lipid facilitates the delivery of liposomal siRNA and gene silencing activity in vitro and in vivo

scientific article published on September 20, 2012

A solid support with a hydroxyallyl linker, full parts of which are potentially reusable for the synthesis of oligonucleotides.

scientific article

An approach to transgene expression in liver endothelial cells using a liposome-based gene vector coated with hyaluronic acid.

scientific article

Analysis of Pseudomonas aeruginosa diguanylate cyclases and phosphodiesterases reveals a role for bis-(3'-5')-cyclic-GMP in virulence

scientific journal article

Biochemical and physiological characterization of a BLUF protein-EAL protein complex involved in blue light-dependent degradation of cyclic diguanylate in the purple bacterium Rhodopseudomonas palustris.

scientific article published on 23 November 2010

Control of formation and cellular detachment from Shewanella oneidensis MR-1 biofilms by cyclic di-GMP

scientific article

Cyclic di-GMP stimulates protective innate immunity in bacterial pneumonia

scientific article

Development of a novel DNA aptamer ligand targeting to primary cultured tumor endothelial cells by a cell-based SELEX method

scientific article

Direct interaction between sensor kinase proteins mediates acute and chronic disease phenotypes in a bacterial pathogen.

scientific article published on January 2009

Effect of cyclic bis(3'-5')diguanylic acid and its analogs on bacterial biofilm formation

scientific article published on December 2009

Ethyl(methyl)dioxirane as an efficient reagent for the oxidation of nucleoside phosphites into phosphates under nonbasic anhydrous conditions

scientific article published on 01 March 2001

Gene silencing via RNAi and siRNA quantification in tumor tissue using MEND, a liposomal siRNA delivery system.

scientific article published on 9 April 2013

Identification of ligand analogues that control c-di-GMP riboswitches.

scientific article

Intracellular observation of nanocarriers modified with a mitochondrial targeting signal peptide

scientific article published on June 2, 2013

Isolation and culture of microvascular endothelial cells from murine inguinal and epididymal adipose tissues

scientific article published on 20 March 2010

RNAi-mediated gene knockdown and anti-angiogenic therapy of RCCs using a cyclic RGD-modified liposomal-siRNA system

scientific article published on 11 October 2013

STING is a direct innate immune sensor of cyclic di-GMP

scientific article

Synthesis and evaluation of stearylated hyaluronic acid for the active delivery of liposomes to liver endothelial cells

scientific article published on 01 January 2011

Synthesis of cyclic bis(3'-5')-2'-deoxyguanylic/guanylic acid (c-dGpGp) and its biological activities to microbes.

scientific article published in October 2007

The Anaplasma phagocytophilum PleC histidine kinase and PleD diguanylate cyclase two-component system and role of cyclic Di-GMP in host cell infection.

scientific article published on 31 October 2008

The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the in vivo interferon response to Listeria monocytogenes and cyclic dinucleotides

scientific article

The innate immune DNA sensor cGAS produces a noncanonical cyclic dinucleotide that activates human STING

scientific article

The second messenger bis-(3'-5')-cyclic-GMP and its PilZ domain-containing receptor Alg44 are required for alginate biosynthesis in Pseudomonas aeruginosa

scientific article published on 21 July 2007

Therapeutic assessment of cytochrome C for the prevention of obesity through endothelial cell-targeted nanoparticulate system.

scientific article published on 8 January 2013

c-di-GMP as a vaccine adjuvant enhances protection against systemic methicillin-resistant Staphylococcus aureus (MRSA) infection.

scientific article published on 9 May 2009

c-di-GMP is an effective immunomodulator and vaccine adjuvant against pneumococcal infection.

scientific article published on 18 July 2008