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List of works by Manuela Tosin

A Light-Activated Acyl Carrier Protein "Trap" for Intermediate Capture in Type II Iterative Polyketide Biocatalysis

scientific article published on 09 October 2019

A Photoactivatable Small-Molecule Probe for the In Vivo Capture of Polyketide Intermediates

scientific article published on 16 October 2019

A genomics-led approach to deciphering the mechanism of thiotetronate antibiotic biosynthesis.

scientific article

A study of the epoxidation of 6-deoxyhex-5-enopyranosides. 1,5-Dicarbonyl derivatives and novel synthetic routes to D-xylo-hexos-5-ulose and D-lyxo-hexos-5-ulose

scientific article published in May 2002

Biosynthesis of the putative siderophore erythrochelin requires unprecedented crosstalk between separate nonribosomal peptide gene clusters

scientific article

Chemical chain termination resolves the timing of ketoreduction in a partially reducing iterative type I polyketide synthase

scientific article published on 28 October 2015

Chemical probes for the functionalization of polyketide intermediates

scientific article

Chemical probing of thiotetronate bio-assembly

scientific article

Corrigendum to “Synthesis of sugar-lactams from azides of glucuronic acid”

scholarly article published in Carbohydrate Research

Covalent linkage mediates communication between ACP and TE domains in modular polyketide synthases

scientific article

Development of Carbohydrate-Based Scaffolds for Restricted Presentation of Recognition Groups. Extension to Divalent Ligands and Implications for the Structure of Dimerized Receptors

article

Glycosidation reactions of silyl ethers with conformationally inverted donors derived from glucuronic acid: stereoselective synthesis of glycosides and 2-deoxyglycosides

scientific article

Glycosidation–Anomerisation Reactions of 6,1-Anhydroglucopyranuronic Acid and Anomerisation of β-D-Glucopyranosiduronic Acids Promoted by SnCl4

High-Resolution Tandem Mass Spectrometry for Nonribosomal Peptide and Polyketide Analysis

In vitro reconstruction of tetronate RK-682 biosynthesis

scientific article published on 20 December 2009

In vivo trapping of polyketide intermediates from an assembly line synthase using malonyl carba(dethia)-N-acetyl cysteamines

scientific article published on 8 February 2011

Insights into 6-Methylsalicylic Acid Bio-assembly by Using Chemical Probes.

scientific article published on 2 February 2016

Insights into lasalocid A ring formation by chemical chain termination in vivo

scientific article published on 24 October 2011

Insights into protein-protein and enzyme-substrate interactions in modular polyketide synthases.

scientific article published on July 2010

Insights into the stereospecificity of ketoreduction in a modular polyketide synthase

scientific article published on 21 February 2011

Malonyl carba(dethia)- and malonyl oxa(dethia)-coenzyme A as tools for trapping polyketide intermediates.

scientific article

N-Glycosyl-thiophene-2-carboxamides: synthesis, structure and effects on the growth of diverse cell types

scientific article published on 22 May 2006

Novel Synthesis of the Glycosidase Inhibitor Deoxymannojirimycin and of a Synthetic Precursord-lyxo-Hexos-5-ulose

scientific article published on 01 October 2001

Novel chemical probes for the investigation of nonribosomal peptide assembly.

scientific article

Phenylenediamine-based bivalent glycocyclophanes: synthesis and analysis of the influence of scaffold rigidity and ligand spacing on lectin binding in cell systems with different glycomic profiles

scientific article published on 23 September 2009

Second-generation probes for biosynthetic intermediate capture: towards a comprehensive profiling of polyketide assembly

scientific article (publication date: 16 August 2016)

Structural Basis for the Activity and Substrate Specificity of Fluoroacetyl-CoA Thioesterase FlK

scientific article

Structural Characterization of Polyketides Using High Mass Accuracy Tandem Mass Spectrometry

scientific article published on 04 October 2012

Synthesis and structural analysis of the anilides of glucuronic acid and orientation of the groups on the carbohydrate scaffolding

scientific article published in May 2005

Synthesis of Structurally Diverse and Defined Bivalent Mannosides on Saccharide Scaffolding

article published in 2005

Synthesis of structurally defined scaffolds for bivalent ligand display based on glucuronic acid anilides. The degree of tertiary amide isomerism and folding depends on the configuration of a glycosyl azide

scientific article

Synthesis of sugar-lactams from azides of glucuronic acid

article by Christina Loukou et al published September 2007 in Carbohydrate Research

Synthesis of α-Glucuronic Acid and Amide Derivatives in the Presence of a Participating 2-Acyl Protecting Group

scientific article published on 01 October 2002

Synthetic chain terminators off-load intermediates from a type I polyketide synthase

scientific article published in March 2010

The polyketide backbone of thiolactomycin is assembled by an unusual iterative polyketide synthase

scientific article

The synthesis of cyclic imidates from amides of glucuronic acid and investigation of glycosidation reactions

Triggering the expression of a silent gene cluster from genetically intractable bacteria results in scleric acid discovery ⬇️

article

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