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Authors whose works are in public domain in at least one jurisdiction

List of works by Daniel Rader

A Common Variant on Chromosome 9p21 Affects the Risk of Myocardial Infarction

A Drug Screen using Human iPSC-Derived Hepatocyte-like Cells Reveals Cardiac Glycosides as a Potential Treatment for Hypercholesterolemia.

scientific article published in April 2017

A Gaussian copula approach for the analysis of secondary phenotypes in case-control genetic association studies

scientific article

A Novel APOC2 Missense Mutation Causing Apolipoprotein C-II Deficiency With Severe Triglyceridemia and Pancreatitis.

scientific article published on 13 February 2017

A Novel Generalized Lipodystrophy-Associated Progeroid Syndrome Due to Recurrent Heterozygous LMNA p.T10I Mutation.

scientific article published on 15 December 2017

A Protein-Truncating HSD17B13 Variant and Protection from Chronic Liver Disease.

scientific article published in March 2018

A coding variant in SR-BI (I179N) significantly increases atherosclerosis in mice

scientific article published on May 31, 2013

A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease

scientific article

A dose-titration and comparative study of rosuvastatin and atorvastatin in patients with homozygous familial hypercholesterolaemia

scientific article published on 28 August 2007

A genome-first approach to aggregating rare genetic variants in LMNA for association with electronic health record phenotypes

scientific article published on 06 August 2019

A genome-wide association study for coronary artery disease identifies a novel susceptibility locus in the major histocompatibility complex

scientific article published on 7 February 2012

A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease

scientific article

A genome-wide association study reveals variants in ARL15 that influence adiponectin levels

scientific article

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium

scientific article

A human APOC3 missense variant and monoclonal antibody accelerate apoC-III clearance and lower triglyceride-rich lipoprotein levels

scientific article

A naturally occurring variant of endothelial lipase associated with elevated HDL exhibits impaired synthesis

scientific article published on 03 May 2009

A novel ApoA-I truncation (ApoA-IMytilene) associated with decreased ApoA-I production

scientific article published on 2 June 2014

A novel approach to measuring macrophage-specific reverse cholesterol transport in vivo in humans.

scientific article

A null mutation in ANGPTL8 does not associate with either plasma glucose or type 2 diabetes in humans

scientific article published on 28 January 2016

A phase III randomized trial evaluating alirocumab 300 mg every 4 weeks as monotherapy or add-on to statin: ODYSSEY CHOICE I.

scientific article published on 31 August 2016

A pilot trial to examine the effect of high-dose niacin on arterial wall inflammation using fluorodeoxyglucose positron emission tomography.

scientific article published on 21 February 2015

A randomized study comparing the effects of a low-carbohydrate diet and a conventional diet on lipoprotein subfractions and C-reactive protein levels in patients with severe obesity

scientific article published on 01 September 2004

A regression framework to uncover pleiotropy in large-scale electronic health record data

scientific article published on 01 October 2019

A second independent locus within DMRT1 is associated with testicular germ cell tumor susceptibility

scientific journal article

A systematic study of modulation of ADAM-mediated ectodomain shedding by site-specific O-glycosylation.

scientific article

A variant of the gene encoding leukotriene A4 hydrolase confers ethnicity-specific risk of myocardial infarction

scientific article published on 10 November 2005

AAV vectors expressing LDLR gain-of-function variants demonstrate increased efficacy in mouse models of familial hypercholesterolemia

scientific article published on 14 July 2014

ANGPTL3 Deficiency and Protection Against Coronary Artery Disease

scientific article published on 29 March 2017

ATP binding cassette family A protein 1 determines hexosylceramide and sphingomyelin levels in human and mouse plasma

article

ATP-Binding Cassette Transporter A1 Deficiency in Human Induced Pluripotent Stem Cell-Derived Hepatocytes Abrogates HDL Biogenesis and Enhances Triglyceride Secretion

scientific article published on 14 March 2017

Abnormal in vivo metabolism of apoB-containing lipoproteins in human apoE deficiency

scientific article

Abnormal lipoprotein particles and cholesterol efflux capacity in patients with psoriasis

scientific article published on 21 July 2012

Acute inflammation increases selective uptake of HDL cholesteryl esters into adrenals of mice overexpressing human sPLA2.

scientific article published on 11 March 2003

Adeno-associated virus serotype 8 gene therapy leads to significant lowering of plasma cholesterol levels in humanized mouse models of homozygous and heterozygous familial hypercholesterolemia

scientific article published on 14 November 2012

Adeno-associated viruses as liver-directed gene delivery vehicles: focus on lipoprotein metabolism

scientific article published on January 2013

Adipocyte enhancer-binding protein 1 is a potential novel atherogenic factor involved in macrophage cholesterol homeostasis and inflammation

scholarly article

Adipose modulation of high-density lipoprotein cholesterol: implications for obesity, high-density lipoprotein metabolism, and cardiovascular disease.

scientific article published on October 2011

An inflammatory cascade leading to hyperresistinemia in humans

scientific article

Anacetrapib lowers LDL by increasing ApoB clearance in mildly hypercholesterolemic subjects

scientific article published on 11 May 2015

Anacetrapib lowers LDL by increasing ApoB clearance in mildly hypercholesterolemic subjects

scientific article published on 01 April 2016

Angiopoietin-like protein 3 inhibits lipoprotein lipase activity through enhancing its cleavage by proprotein convertases

scientific journal article

Antimitogenic effects of HDL and APOE mediated by Cox-2-dependent IP activation

scientific article

Antisense oligonucleotides for atherosclerotic disease

scientific article published on 06 April 2020

Anti‐oxidative and cholesterol efflux capacities of high‐density lipoprotein are reduced in ischaemic cardiomyopathy

scientific article published on May 24, 2013

Apolipoprotein A-I and cholesterol efflux: the good, the bad, and the modified.

scientific article published on May 2014

Apolipoprotein A-I deficiency results in markedly increased atherosclerosis in mice lacking the LDL receptor

scientific article published on 21 August 2003

Apolipoprotein E and coronary disease: a puzzling paradox

scientific article published in June 2006

Apolipoprotein E suppresses the type I inflammatory response in vivo

scientific article published on 22 September 2005

Apolipoprotein E-mediated cell cycle arrest linked to p27 and the Cox2-dependent repression of miR221/222

scientific article published on December 19, 2012

Apolipoprotein(a) isoform size, lipoprotein(a) concentration, and coronary artery disease: a mendelian randomisation analysis

scientific article

Apolipoproteins regulate the kinetics of endothelial lipase-mediated hydrolysis of phospholipids in reconstituted high-density lipoproteins

scientific article published on 01 September 2004

Assessment of coronary artery disease by cardiac computed tomography: a scientific statement from the American Heart Association Committee on Cardiovascular Imaging and Intervention, Council on Cardiovascular Radiology and Intervention, and Committe

scientific article

Association of APOC3 Loss-of-Function Mutations With Plasma Lipids and Subclinical Atherosclerosis: The Multi-Ethnic BioImage Study

scientific article published in November 2015

Association of APOL1 Risk Alleles With Cardiovascular Disease in Blacks in the Million Veteran Program

scientific article published on 24 July 2019

Association of FADS1/2 Locus Variants and Polyunsaturated Fatty Acids With Aortic Stenosis

scientific article published on 18 March 2020

Association of HDL cholesterol efflux capacity with incident coronary heart disease events: a prospective case-control study

scientific article

Association of Inherited Pathogenic Variants in Checkpoint Kinase 2 (CHEK2) With Susceptibility to Testicular Germ Cell Tumors

scientific article published on 01 April 2019

Association of Rare and Common Variation in the Lipoprotein Lipase Gene With Coronary Artery Disease

scientific article

Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks

scientific article

Association of the V122I Hereditary Transthyretin Amyloidosis Genetic Variant With Heart Failure Among Individuals of African or Hispanic/Latino Ancestry

scientific article published on 01 December 2019

Association of the vitamin D metabolism gene CYP24A1 with coronary artery calcification

scientific article

Associations between cardiovascular disease, cancer, and very low high-density lipoprotein cholesterol in the REasons for Geographical and Racial Differences in Stroke (REGARDS) study

scientific article published on 01 January 2019

Author Correction: Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations

scientific article published on 17 May 2019

Author Correction: Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations

scientific article published on 03 September 2019

Autophagy Is Required for Sortilin-Mediated Degradation of Apolipoprotein B100.

scientific article published on 4 January 2018

Beyond high-density lipoprotein cholesterol levels evaluating high-density lipoprotein function as influenced by novel therapeutic approaches

scientific article published in June 2008

Biodistribution of AAV8 vectors expressing human low-density lipoprotein receptor in a mouse model of homozygous familial hypercholesterolemia

scientific article

Biological, clinical and population relevance of 95 loci for blood lipids

scientific article

Biomarkers of Calcific Aortic Valve Disease

scientific article published on 2 February 2017

Both the peroxisome proliferator-activated receptor delta agonist, GW0742, and ezetimibe promote reverse cholesterol transport in mice by reducing intestinal reabsorption of HDL-derived cholesterol

scientific article

C-Reactive Protein and Coronary Artery Calcification

scientific article published on 21 August 2003

CD44 expressed on both bone marrow-derived and non-bone marrow-derived cells promotes atherogenesis in ApoE-deficient mice

scientific article published on 17 April 2008

CD44 regulates vascular gene expression in a proatherogenic environment

scientific article published in February 2007

CD59 but not DAF deficiency accelerates atherosclerosis in female ApoE knockout mice

scientific article published on 17 March 2009

CETP (Cholesteryl Ester Transfer Protein) Inhibition With Anacetrapib Decreases Production of Lipoprotein(a) in Mildly Hypercholesterolemic Subjects

scientific article

COVID-19 outcomes and the human genome

scientific article published on 12 May 2020

CRISPR/Cas9-Mediated Gene Editing in Human iPSC-Derived Macrophage Reveals Lysosomal Acid Lipase Function in Human Macrophages-Brief Report

scientific article

CXCL12: a new player in coronary disease identified through human genetics

scientific article published on August 2010

CXCL16 is a marker of inflammation, atherosclerosis, and acute coronary syndromes in humans

scientific article (publication date: 30 January 2007)

Candidate gene association resource (CARe): design, methods, and proof of concept

scientific article

Candidate gene association study of coronary artery calcification in chronic kidney disease: findings from the CRIC study (Chronic Renal Insufficiency Cohort).

scientific article published on 30 May 2013

Cardiovascular protection by ApoE and ApoE-HDL linked to suppression of ECM gene expression and arterial stiffening

scientific article published on 25 October 2012

Cascade Screening for Familial Hypercholesterolemia and the Use of Genetic Testing.

scientific article published in July 2017

Causal Assessment of Serum Urate Levels in Cardiometabolic Diseases Through a Mendelian Randomization Study

scientific article

Cell lipid metabolism modulators 2-bromopalmitate, D609, monensin, U18666A and probucol shift discoidal HDL formation to the smaller-sized particles: implications for the mechanism of HDL assembly

scientific article published on 24 September 2016

Characterization of the lipolytic activity of endothelial lipase

scientific article published on 01 June 2002

Cholesterol Efflux Capacity and Pre-Beta-1 HDL Concentrations Are Increased in Dyslipidemic Patients Treated With Evacetrapib.

scientific article published on November 2015

Cholesterol efflux and atheroprotection: advancing the concept of reverse cholesterol transport

scientific article

Cholesterol efflux capacity of high-density lipoprotein correlates with survival and allograft vasculopathy in cardiac transplant recipients

scientific article published on 15 July 2016

Cholesterol efflux capacity, high-density lipoprotein function, and atherosclerosis

scientific article

Cholesterol efflux capacity: full steam ahead or a bump in the road?

scientific article published in July 2013

Cholesterol ester transfer protein inhibition by TA-8995 in patients with mild dyslipidaemia (TULIP): a randomised, double-blind, placebo-controlled phase 2 trial

scientific article (publication date: August 2015)

Cholesteryl Ester Transfer Protein Inhibition With Anacetrapib Decreases Fractional Clearance Rates of High-Density Lipoprotein Apolipoprotein A-I and Plasma Cholesteryl Ester Transfer Protein

scientific article published on 10 March 2016

Cholesteryl ester transfer protein and coronary artery disease: an observation with therapeutic implications

scientific article published in September 2004

Cholesteryl ester transfer protein: a novel target for raising HDL and inhibiting atherosclerosis

scientific article (publication date: February 2003)

Circulating and tissue matricellular RNA and protein expression in calcific aortic valve disease

scientific article published on 24 February 2020

Clinical Genetic Testing for Familial Hypercholesterolemia

scientific article published on 01 August 2018

Clinical Implications of Lipid Genetics for Cardiovascular Disease

scientific article published on October 2010

Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease

scientific article published on 2 March 2016

Combined effects of cholesterol reduction and apolipoprotein A-I expression on atherosclerosis in LDL receptor deficient mice

scientific article

Common variants associated with plasma triglycerides and risk for coronary artery disease

scientific article

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways

scientific article

Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer

scientific article

Comparative in vivo metabolism of apolipoproteins E2 and E4 in heterozygous apoE2/4 subjects

scientific article published on 01 November 2002

Comparison of Coronary Artery Calcium Scores Between Patients With Psoriasis and Type 2 Diabetes

scientific article published on 24 August 2016

Comparison of high-density lipoprotein cholesterol to apolipoprotein A-I and A-II to predict coronary calcium and the effect of insulin resistance

scientific article

Complete deficiency of the low-density lipoprotein receptor is associated with increased apolipoprotein B-100 production.

scientific article published on 6 January 2005

Complete prevention of atherosclerosis in apoE-deficient mice by hepatic human apoE gene transfer with adeno-associated virus serotypes 7 and 8.

scientific article published on 8 June 2006

Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies

scientific article

Coronary artery calcification and cardiovascular risk factors: impact of the analytic approach

scientific article published in March 2004

Coronary artery calcification at electron beam computed tomography is increased in asymptomatic type 2 diabetics independent of traditional risk factors

scientific article published in December 2002

Correcting population stratification in genetic association studies using a phylogenetic approach

scientific article

Correlates and Predictors of Cerebrospinal Fluid Cholesterol Efflux Capacity from Neural Cells, a Family of Biomarkers for Cholesterol Epidemiology in Alzheimer's Disease

scientific article published on 01 January 2020

Could exercise metabolomics pave the way for gymnomimetics?

scientific article published on 01 July 2010

Creatine kinase, a magnetic resonance-detectable marker gene for quantification of liver-directed gene transfer.

scientific article published in December 2005

Decreased Expression of ARV1 Results in Cholesterol Retention in the Endoplasmic Reticulum and Abnormal Bile Acid Metabolism*

scientific article published on July 27, 2010

Deep Apolipoprotein Proteomics to Uncover Mechanisms of Coronary Disease Risk

scientific article published on 01 February 2017

Deep RNA Sequencing Uncovers a Repertoire of Human Macrophage Long Intergenic Noncoding RNAs Modulated by Macrophage Activation and Associated With Cardiometabolic Diseases

scientific article published on 13 November 2017

Demystifying triglycerides: a practical approach for the clinician.

scientific article

Dense genotyping of candidate gene loci identifies variants associated with high-density lipoprotein cholesterol

scientific article published on 8 February 2011

Design and synthesis of boronic acid inhibitors of endothelial lipase

scientific article published on December 13, 2011

Design of the Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis (CARDIoGRAM) Study: A Genome-wide association meta-analysis involving more than 22 000 cases and 60 000 controls

scientific article

Determining hepatic triglyceride production in mice: comparison of poloxamer 407 with Triton WR-1339.

scientific article published in July 2005

Diagnostic Yield and Clinical Utility of Sequencing Familial Hypercholesterolemia Genes in Patients With Severe Hypercholesterolemia

scientific article

Diet-dependent cardiovascular lipid metabolism controlled by hepatic LXRalpha

scientific article published in May 2005

Differential association of plasma angiopoietin-like proteins 3 and 4 with lipid and metabolic traits

scientific article

Differential network enrichment analysis reveals novel lipid pathways in chronic kidney disease

scientific article published on 01 September 2019

Directional ABCA1-mediated cholesterol efflux and apoB-lipoprotein secretion in the retinal pigment epithelium

scientific article published on 03 August 2018

Discovery and refinement of loci associated with lipid levels

scientific article

Discovery and validation of new molecular targets in treating dyslipidemia: the role of human genetics

scientific article published in August 2009

Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis

scientific article published on 15 June 2020

Disentangling the Causal Association of Plasma Lipid Traits and Type 2 Diabetes Using Human Genetics

scientific article published on 3 August 2016

Dose-Dependent Acceleration of High-Density Lipoprotein Catabolism by Endothelial Lipase

scientific article published on September 29, 2003

Drugs in development: targeting high-density lipoprotein metabolism and reverse cholesterol transport

scientific article

Dyslipidaemia: cardiovascular prevention--end of the road for niacin?

scientific article published on 02 September 2014

Dyslipidemia in insulin resistance: clinical challenges and adipocentric therapeutic frontiers

scientific article published on August 2008

ERRATUM: Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

article by Matthew B. Lanktree et al published June 2012 in American Journal of Human Genetics

Effect of 2 Psoriasis Treatments on Vascular Inflammation and Novel Inflammatory Cardiovascular Biomarkers: A Randomized Placebo-Controlled Trial

scientific article published on 01 June 2018

Effect of Access to Prescribed PCSK9 Inhibitors on Cardiovascular Outcomes

scientific article published on 23 July 2019

Effect of interleukin 1β inhibition in cardiovascular disease

scientific article published on December 1, 2012

Effect of rosiglitazone on HDL metabolism in subjects with metabolic syndrome and low HDL

scientific article published on October 22, 2010

Effects of CETP inhibition on triglyceride-rich lipoprotein composition and apoB-48 metabolism

scientific article

Effects of CETP inhibition with anacetrapib on metabolism of VLDL-TG and plasma apolipoproteins C-II, C-III, and E

scientific article

Effects of Genetic Variants Associated with Familial Hypercholesterolemia on Low-Density Lipoprotein-Cholesterol Levels and Cardiovascular Outcomes in the Million Veteran Program

scientific article published on 01 December 2018

Effects of Niacin, Statin, and Fenofibrate on Circulating Proprotein Convertase Subtilisin/Kexin Type 9 Levels in Patients With Dyslipidemia

scientific article published on 31 October 2014

Effects of an inhibitor of cholesteryl ester transfer protein on HDL cholesterol

scientific article

Effects of cholesteryl ester transfer protein inhibition on apolipoprotein A-II-containing HDL subspecies and apolipoprotein A-II metabolism

scientific article published on 3 February 2009

Effects of cholesteryl ester transfer protein inhibition on high-density lipoprotein subspecies, apolipoprotein A-I metabolism, and fecal sterol excretion.

scientific article published on 10 March 2005

Effects of nevirapine and efavirenz on HDL cholesterol levels and reverse cholesterol transport in mice

scientific article published on 27 September 2008

Effects of nonlipolytic ligand function of endothelial lipase on high density lipoprotein metabolism in vivo

scientific article published on 8 August 2003

Effects of pioglitazone on lipoproteins, inflammatory markers, and adipokines in nondiabetic patients with metabolic syndrome

scientific article

Effects of rosiglitazone on lipids, adipokines, and inflammatory markers in nondiabetic patients with low high-density lipoprotein cholesterol and metabolic syndrome

scientific article published on 15 December 2005

Effects of the cholesteryl ester transfer protein inhibitor torcetrapib on VLDL apolipoprotein E metabolism.

scientific article published on 21 November 2007

Effects of the cholesteryl ester transfer protein inhibitor torcetrapib on apolipoprotein B100 metabolism in humans

scientific article published on 30 March 2006

Effects of the cholesteryl ester transfer protein inhibitor, TA-8995, on cholesterol efflux capacity and high-density lipoprotein particle subclasses

scientific article published on 25 June 2016

Efficacy and Safety of Alirocumab 300 mg Every 4 Weeks in Individuals With Type 2 Diabetes on Maximally Tolerated Statin

scientific article published on 01 November 2019

Efficacy and Safety of Alirocumab in Patients with Heterozygous Familial Hypercholesterolemia and LDL-C of 160 mg/dl or Higher

scientific article

Efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hypercholesterolaemia: a single-arm, open-label, phase 3 study

scientific article published on November 2, 2012

Efficacy and safety of lipid lowering by alirocumab in chronic kidney disease.

scientific article published on 8 March 2018

Emerging role of FDG-PET/CT in assessing atherosclerosis in large arteries

scientific article

Emerging therapies targeting high-density lipoprotein metabolism and reverse cholesterol transport

scientific article

Endogenously produced endothelial lipase enhances binding and cellular processing of plasma lipoproteins via heparan sulfate proteoglycan-mediated pathway

scientific article published on 16 June 2003

Endothelial cells secrete triglyceride lipase and phospholipase activities in response to cytokines as a result of endothelial lipase

scientific article published on 27 February 2003

Endothelial lipase concentrations are increased in metabolic syndrome and associated with coronary atherosclerosis

scientific article

Endothelial lipase is a critical determinant of high-density lipoprotein-stimulated sphingosine 1-phosphate-dependent signaling in vascular endothelium.

scientific article

Endothelial lipase is increased in vivo by inflammation in humans

scientific article published on 22 January 2008

Endothelial lipase is less effective at influencing HDL metabolism in vivo in mice expressing apoA-II

scientific article published on 30 July 2006

Endothelial lipase promotes the catabolism of ApoB-containing lipoproteins

scientific article published on 29 April 2004

Endothelial lipase: a modulator of lipoprotein metabolism upregulated by inflammation

scientific article published in July 2004

Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation

scientific article published in July 2017

Evaluation of the Pooled Cohort Equations for Prediction of Cardiovascular Risk in a Contemporary Prospective Cohort

scientific article

Evidence That Hepatic Lipase and Endothelial Lipase Have Different Substrate Specificities for High-Density Lipoprotein Phospholipids

scientific article published on November 25, 2003

Exome sequencing and directed clinical phenotyping diagnose cholesterol ester storage disease presenting as autosomal recessive hypercholesterolemia

scientific article published on 26 September 2013

Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction

scientific article

Exome sequencing in suspected monogenic dyslipidemias

scientific article

Exome-wide association study of plasma lipids in >300,000 individuals

scientific article published on 30 October 2017

Experimental Therapeutics for Challenging Clinical Care of a Patient with an Extremely Rare Homozygous APOC2 Mutation

scientific article published on 27 March 2020

Expression of cholesteryl ester transfer protein in mice promotes macrophage reverse cholesterol transport

scientific article published on 20 August 2007

Expression of human hepatic lipase in the rabbit model preferentially enhances the clearance of triglyceride-enriched versus native high-density lipoprotein apolipoprotein A-I.

scientific article

Extended-release niacin acutely suppresses postprandial triglyceridemia

scientific article

FBN1 Coding Variants and Nonsyndromic Aortic Disease

scientific article published on 18 June 2019

Familial Chylomicronemia Syndrome With a Novel Homozygous LPL Mutation Identified in Three Siblings in Their 50s

scientific article published on 19 November 2019

Familial hypercholesterolemia: screening, diagnosis and management of pediatric and adult patients: clinical guidance from the National Lipid Association Expert Panel on Familial Hypercholesterolemia

scientific article

Familial hypercholesterolemia: screening, diagnosis and management of pediatric and adult patients: clinical guidance from the National Lipid Association Expert Panel on Familial Hypercholesterolemia

scientific article published on 11 March 2011

Familial hypercholesterolemias: prevalence, genetics, diagnosis and screening recommendations from the National Lipid Association Expert Panel on Familial Hypercholesterolemia

scientific article published on 3 April 2011

Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms

scientific article published on 22 May 2017

Fine Mapping and Functional Analysis Reveal a Role of SLC22A1 in Acylcarnitine Transport

scientific article

Fish oil promotes macrophage reverse cholesterol transport in mice

scientific article published on 2 July 2009

Flaxseed and cardiovascular risk factors: results from a double blind, randomized, controlled clinical trial.

scientific article published in February 2008

Flaxseed reduces plasma cholesterol levels in hypercholesterolemic mouse models

scientific article published on February 2007

Fluorescent green plaques: light at the end of the catheter?

scientific article published on July 2011

From Darwin's finches to canaries in the coal mine--mining the genome for new biology

scientific article

From Loci to Biology: Functional Genomics of Genome-Wide Association for Coronary Disease

scientific article published on February 2016

From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus

scientific article

Functional analysis and transcriptomic profiling of iPSC-derived macrophages and their application in modeling Mendelian disease

scientific article

Gender differences in the association of C-reactive protein with coronary artery calcium in type-2 diabetes

scientific article

Gene Therapy in a Humanized Mouse Model of Familial Hypercholesterolemia Leads to Marked Regression of Atherosclerosis

scientific article (publication date: 19 October 2010)

Gene therapy for dyslipidemia: a review of gene replacement and gene inhibition strategies

scientific article published in June 2010

Gene therapy for lipoprotein disorders

scientific article

Gene transfer of wild-type apoA-I and apoA-I Milano reduce atherosclerosis to a similar extent

scientific article published on 2 May 2007

Gene-based interaction analysis by incorporating external linkage disequilibrium information

scientific article published on 6 October 2010

Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci

scientific article published on 20 February 2014

Gene-centric meta-analysis of lipid traits in African, East Asian and Hispanic populations

scientific article

Generation of iPSCs as a Pooled Culture Using Magnetic Activated Cell Sorting of Newly Reprogrammed Cells

scientific article published on 17 August 2015

Genetic Architecture of Abdominal Aortic Aneurysm in the Million Veteran Program

scientific article published on 28 September 2020

Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease

scientific article

Genetic Variants Associated With Plasma Lipids Are Associated With the Lipid Response to Niacin

scientific article published on 01 October 2018

Genetic ablation of Adamts13 gene dramatically accelerates the formation of early atherosclerosis in a murine model.

scientific article

Genetic analysis for a shared biological basis between migraine and coronary artery disease

scientific article published on June 2015

Genetic and Epigenetic Fine Mapping of Complex Trait Associated Loci in the Human Liver

scientific article published on 13 June 2019

Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease

scientific article published on 24 May 2017

Genetic basis of atherosclerosis: insights from mice and humans

scientific article

Genetic coding variants in the niacin receptor, hydroxyl-carboxylic acid receptor 2, and response to niacin therapy

scientific article published on 16 June 2017

Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes

scientific article published on 13 June 2018

Genetic manipulation of the ApoF/Stat2 locus supports an important role for type I interferon signaling in atherosclerosis.

scientific article published on 10 January 2014

Genetic regulation of nonsense-mediated decay underlies association with risk of severe COVID-19

scientific article

Genetic variants influencing circulating lipid levels and risk of coronary artery disease

scientific article published on 23 September 2010

Genetic-Variation-Driven Gene-Expression Changes Highlight Genes with Important Functions for Kidney Disease

scientific article published on June 2017

Genetically Determined Birthweight Associates with Atrial Fibrillation: A Mendelian Randomization Study

scientific article published on 27 April 2020

Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program

article

Genetics of height and risk of atrial fibrillation: A Mendelian randomization study

scientific article published on 08 October 2020

Genetics of increased HDL cholesterol levels: insights into the relationship between HDL metabolism and atherosclerosis

scientific article published in October 2003

Genetics of lipid traits: Genome-wide approaches yield new biology and clues to causality in coronary artery disease

scientific article published on 12 June 2014

Genome-wide approaches to finding novel genes for lipid traits: the start of a long road

scientific article published on 01 October 2008

Genome-wide association analysis of venous thromboembolism identifies new risk loci and genetic overlap with arterial vascular disease

scientific article published on 01 November 2019

Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants

scientific article

Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India

scientific article

Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm

scientific journal article

Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations

scientific article published on 02 April 2019

Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project

scientific article

Genome-wide association study of peripheral artery disease in the Million Veteran Program

scientific article published on 08 July 2019

Genomic Risk Stratification Predicts All-Cause Mortality After Cardiac Catheterization

scientific article published on 01 November 2018

Genomic integrity of human induced pluripotent stem cells across nine studies in the NHLBI NextGen program

scientific article published on 06 May 2020

Genomic medicine in the prevention and treatment of atherosclerotic cardiovascular disease

scientific article published on 01 June 2012

Genomic profiling of human vascular cells identifies TWIST1 as a causal gene for common vascular diseases

scientific article published on 09 January 2020

Genomics-First Evaluation of Heart Disease Associated With Titin-Truncating Variants

scientific article published on 20 June 2019

GlycA Is a Novel Biomarker of Inflammation and Subclinical Cardiovascular Disease in Psoriasis.

scientific article published on 21 September 2016

Glycosylation of endothelial lipase at asparagine-116 reduces activity and the hydrolysis of native lipoproteins in vitro and in vivo

scientific article published on 24 February 2007

Guggulipid for the treatment of hypercholesterolemia: a randomized controlled trial

scientific article (publication date: 13 August 2003)

HDL (High-Density Lipoprotein) Subclasses, Lipid Content, and Function Trajectories Across the Menopause Transition: SWAN-HDL Study

scientific article published on 03 December 2020

HDL Cholesterol Metabolism and the Risk of CHD: New Insights from Human Genetics

scientific article

HDL and cardiovascular disease

scientific article

HDL re-examined

scientific article

Health disparities among adult patients with a phenotypic diagnosis of familial hypercholesterolemia in the CASCADE-FH™ patient registry

scientific article published on 6 October 2017

Hepatic expression of scavenger receptor class B type I (SR-BI) is a positive regulator of macrophage reverse cholesterol transport in vivo

scientific article

Hepatic metal ion transporter ZIP8 regulates manganese homeostasis and manganese-dependent enzyme activity.

scientific article published on 8 May 2017

Hepatic protein phosphatase 1 regulatory subunit 3B (Ppp1r3b) promotes hepatic glycogen synthesis and thereby regulates fasting energy homeostasis.

scientific article published on 4 May 2017

Hepatic sortilin regulates both apolipoprotein B secretion and LDL catabolism

scientific article

Heterozygous ATP-binding Cassette Transporter G5 Gene Deficiency and Risk of Coronary Artery Disease

scientific article published on 30 August 2020

High density lipoprotein cholesterol and cancer: Marker or causative?

scientific article published on 04 June 2018

High-Density Lipoprotein (HDL) Phospholipid Content and Cholesterol Efflux Capacity Are Reduced in Patients With Very High HDL Cholesterol and Coronary Disease

scientific article

High-density lipoprotein cholesterol therapies: the next frontier in lipid management

scientific article

High-density lipoprotein hydrolysis by endothelial lipase activates PPARalpha: a candidate mechanism for high-density lipoprotein-mediated repression of leukocyte adhesion.

scientific article

High-density lipoprotein particle number: a better measure to quantify high-density lipoprotein?

scientific article published on 11 July 2012

High-density lipoprotein: NO failure in heart failure.

scientific article published on December 2013

High-density lipoproteins: a consensus statement from the National Lipid Association

scientific article published on 11 August 2013

Higher order lipase gene association with plasma triglycerides

article

Higher plasma CXCL12 levels predict incident myocardial infarction and death in chronic kidney disease: findings from the Chronic Renal Insufficiency Cohort study

scientific article

Human genetics of variation in high-density lipoprotein cholesterol

scientific article published on May 2006

Human genetics shines a light on ischaemic stroke

scientific article published on 19 December 2015

Human knockouts and phenotypic analysis in a cohort with a high rate of consanguinity

scientific article published on April 2017

Human knockouts in a cohort with a high rate of consanguinity

Human secretory phospholipase A2 mediates decreased plasma levels of HDL cholesterol and apoA-I in response to inflammation in human apoA-I transgenic mice

scientific article

ILRUN, a Human Plasma Lipid GWAS Locus, Regulates Lipoprotein Metabolism in Mice

scientific article published on 11 September 2020

Identification and functional characterization in vivo of a novel splice variant of LDLR in rhesus macaques

scientific article (publication date: 16 August 2011)

Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies

scientific article

Identification of genetic variants in endothelial lipase in persons with elevated high-density lipoprotein cholesterol

scientific article published in September 2002

Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease

scientific article published on 4 September 2017

Identification of the active form of endothelial lipase, a homodimer in a head-to-tail conformation

scientific article

Impact of natural selection on global patterns of genetic variation and association with clinical phenotypes at genes involved in SARS-CoV-2 infection

scientific article published on 17 May 2022

Impaired cholesterol efflux capacity and vasculoprotective function of high-density lipoprotein in heart transplant recipients

scientific article published on 24 January 2014

Implementing Genomic Medicine in the Clinic

Implementing genomic medicine in the clinic: the future is here

scientific article published on 10 January 2013

In Memoriam: Julian B. Marsh (1926–2018)

scientific article published in 2019

In vivo modulation of HDL phospholipid has opposing effects on SR-BI- and ABCA1-mediated cholesterol efflux

scientific article published on November 1, 2003

Inactivating mutations in NPC1L1 and protection from coronary heart disease

scientific article

Increased atherosclerosis in mice lacking apolipoprotein A-I attributable to both impaired reverse cholesterol transport and increased inflammation

scientific article published on 8 September 2005

Increased protein nitration burden in the atherosclerotic lesions and plasma of apolipoprotein A-I deficient mice

scientific article published on 05 July 2007

Inflammation induces fibrinogen nitration in experimental human endotoxemia

scientific article

Influence of apolipoprotein A-I domain structure on macrophage reverse cholesterol transport in mice

scientific article published on 11 November 2010

Inhibition of endothelial lipase causes increased HDL cholesterol levels in vivo

scientific article

Inhibition of microsomal triglyceride transfer protein alone or with ezetimibe in patients with moderate hypercholesterolemia

scientific article published on 27 May 2008

Inhibition of microsomal triglyceride transfer protein in familial hypercholesterolemia

scientific article

Intercellular adhesion molecule 1 (ICAM-1) gene variant is associated with coronary artery calcification independent of soluble ICAM-1 levels

scientific article published on 01 December 2004

Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies

scientific article published on 14 March 2012

Interrogation of the Atherosclerosis-Associated SORT1 (Sortilin 1) Locus With Primary Human Hepatocytes, Induced Pluripotent Stem Cell-Hepatocytes, and Locus-Humanized Mice

scientific article published on 2 November 2017

Is the cholesteryl ester transfer protein proatherogenic or antiatherogenic in humans?

scientific article published on 29 October 2007

JCL roundtable: drug treatment of severe forms of familial hypercholesterolemia

scientific article

Knockdown of acyl-CoA:diacylglycerol acyltransferase 2 with antisense oligonucleotide reduces VLDL TG and ApoB secretion in mice

scientific journal article

Knockout of Adamts7, a novel coronary artery disease locus in humans, reduces atherosclerosis in mice

scientific article

Laboratory assessment of HDL heterogeneity and function

scientific article published on 28 March 2008

Lack of MTTP Activity in Pluripotent Stem Cell-Derived Hepatocytes and Cardiomyocytes Abolishes apoB Secretion and Increases Cell Stress.

scientific article published on May 2017

Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies

scientific article

Lack of pathogenic germline DICER1 variants in males with testicular germ-cell tumors

scientific article published on 24 October 2020

Large, Diverse Population Cohorts of hiPSCs and Derived Hepatocyte-like Cells Reveal Functional Genetic Variation at Blood Lipid-Associated Loci

scientific article published in April 2017

Large-Scale Analysis of Determinants, Stability, and Heritability of High-Density Lipoprotein Cholesterol Efflux Capacity

scientific article published on 31 August 2017

Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.

scientific article

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

scientific article

Large-scale association analysis identifies new risk loci for coronary artery disease

scientific article published on 02 December 2012

Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci

scientific article

Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci

scientific article

Lecithin: cholesterol acyltransferase expression has minimal effects on macrophage reverse cholesterol transport in vivo

scientific article published on 29 June 2009

Limitations of Contemporary Guidelines for Managing Patients at High Genetic Risk of Coronary Artery Disease

scientific article published on 01 June 2020

Lipase H, a new member of the triglyceride lipase family synthesized by the intestine

scientific article (publication date: September 2002)

Lipases and HDL metabolism

scientific article

Lipases as modulators of atherosclerosis in murine models

scientific article published on December 2007

Lipid and apolipoprotein ratios: association with coronary artery disease and effects of rosuvastatin compared with atorvastatin, pravastatin, and simvastatin

scientific article published in March 2003

Lipid droplet screen in human hepatocytes identifies TRRAP as a regulator of cellular triglyceride metabolism

scientific article published on 22 June 2021

Lipid-lowering treatment for homozygous familial hypercholesterolaemia – Authors' reply

scientific article published on April 6, 2013

Lipidomic analyses of female mice lacking hepatic lipase and endothelial lipase indicate selective modulation of plasma lipid species.

scientific article

Lipids, Apolipoproteins, and Risk of Atherosclerotic Cardiovascular Disease in Persons With CKD

scientific article published on 25 January 2019

Lipoprotein [a] is cleared from the plasma primarily by the liver in a process mediated by apolipoprotein [a].

scientific article

Lipoprotein(a) and Risk of Myocardial Infarction and Death in Chronic Kidney Disease: Findings From the CRIC Study (Chronic Renal Insufficiency Cohort).

scientific article published on 24 August 2017

Lipoproteins as biomarkers and therapeutic targets in the setting of acute coronary syndrome

scientific article

Lipoproteins, macrophage function, and atherosclerosis: beyond the foam cell?

scientific article

Loci influencing blood pressure identified using a cardiovascular gene-centric array

scientific article published on 8 January 2013

Loci influencing blood pressure identified using a cardiovascular gene-centric array

scientific article

Lomitapide and mipomersen: two first-in-class drugs for reducing low-density lipoprotein cholesterol in patients with homozygous familial hypercholesterolemia

scientific article

Long-Term Efficacy and Safety of the Microsomal Triglyceride Transfer Protein Inhibitor Lomitapide in Patients With Homozygous Familial Hypercholesterolemia

scientific article published in July 2017

Long-term effects of LDL apheresis in patients with severe hypercholesterolemia

scientific article published in December 2005

Longitudinal evaluation and assessment of cardiovascular disease in patients with homozygous familial hypercholesterolemia

scientific article

Longitudinal low density lipoprotein cholesterol goal achievement and cardiovascular outcomes among adult patients with familial hypercholesterolemia: The CASCADE FH registry

scientific article published on 19 August 2019

Loss of Cardioprotective Effects at the ADAMTS7 Locus as a Result of Gene-Smoking Interactions

scientific article published on May 2017

Loss of Function of GALNT2 Lowers High-Density Lipoproteins in Humans, Nonhuman Primates, and Rodents.

scientific article published on August 2016

Loss-of-function variants in endothelial lipase are a cause of elevated HDL cholesterol in humans

scientific article published on 16 March 2009

Macrophage ABCA1 and ABCG1, but not SR-BI, promote macrophage reverse cholesterol transport in vivo

scientific journal article

Macrophage reverse cholesterol transport in mice expressing ApoA-I Milano

scientific article published on 6 August 2009

Macrophage reverse cholesterol transport: key to the regression of atherosclerosis?

scientific article

Macrophage sortilin promotes LDL uptake, foam cell formation, and atherosclerosis

scientific article

Managing diabetic dyslipidemia: beyond statin therapy

scientific article published on February 2009

Measurement of Fractional Synthetic Rates of Multiple Protein Analytes by Triple Quadrupole Mass Spectrometry

scientific article published on January 16, 2012

Measurement of apo(a) kinetics in human subjects using a microfluidic device with tandem mass spectrometry

scientific article published on June 30, 2013

Measurement of waist circumference predicts coronary atherosclerosis beyond plasma adipokines

article

Measures of insulin resistance add incremental value to the clinical diagnosis of metabolic syndrome in association with coronary atherosclerosis

scientific article

Measuring niacin-associated skin toxicity (NASTy) stigmata along with symptoms to aid development of niacin mimetics

scientific article published on 23 January 2017

Mendelian Randomization Analysis of Hemostatic Factors and Their Contribution to Peripheral Artery Disease

scientific article published on 27 August 2020

Meta-analysis and imputation refines the association of 15q25 with smoking quantity

scientific article

Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

scientific article

Metabolic syndrome, components, and cardiovascular disease prevalence in chronic kidney disease: findings from the Chronic Renal Insufficiency Cohort (CRIC) Study

scientific article

Microsomal Triglyceride Transfer Protein Transfers and Determines Plasma Concentrations of Ceramide and Sphingomyelin but Not Glycosylceramide

scientific article

Microsomal prostaglandin E synthase-1 deletion suppresses oxidative stress and angiotensin II-induced abdominal aortic aneurysm formation.

scientific article

Microsomal transfer protein inhibition in humans

scientific article published on June 1, 2013

Mighty Minipig in Fight Against Cardiovascular Disease

scientific article published on January 2, 2013

Mining the LIPG allelic spectrum reveals the contribution of rare and common regulatory variants to HDL cholesterol

scientific article

Mining the Stiffness-Sensitive Transcriptome in Human Vascular Smooth Muscle Cells Identifies Long Noncoding RNA Stiffness Regulators

scientific article

Modulation of HDL metabolism by the niacin receptor GPR109A in mouse hepatocytes

scientific article published on 22 July 2010

Molecular mechanisms responsible for the differential effects of apoE3 and apoE4 on plasma lipoprotein-cholesterol levels.

scientific article published on 14 February 2013

Monogenic hypercholesterolemia: new insights in pathogenesis and treatment

scientific article

Multi-ethnic analysis of lipid-associated loci: the NHLBI CARe project

scientific article

Multi-ethnic genome-wide association study for atrial fibrillation

article

Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis.

scientific article published on 21 November 2016

Multiplexed Targeted Resequencing Identifies Coding and Regulatory Variation Underlying Phenotypic Extremes of High-Density Lipoprotein Cholesterol in Humans

scientific article published on 01 July 2018

Myeloid Tribbles 1 induces early atherosclerosis via enhanced foam cell expansion

scientific article published on 30 October 2019

N-Glycosylation regulates endothelial lipase-mediated phospholipid hydrolysis in apoE- and apoA-I-containing high density lipoproteins

scientific article published on 03 June 2007

NARC-1/PCSK9 and its natural mutants: zymogen cleavage and effects on the low density lipoprotein (LDL) receptor and LDL cholesterol

scientific article

NHLBI Working Group Recommendations to Reduce Lipoprotein(a)-Mediated Risk of Cardiovascular Disease and Aortic Stenosis

scientific article published in January 2018

Neuronal deficiency of ARV1 causes an autosomal recessive epileptic encephalopathy

scientific article

New targets and emerging therapies for reducing LDL cholesterol

scientific article published on December 2007

Non-Clinical Study Examining AAV8.TBG.hLDLR Vector-Associated Toxicity in Chow-Fed Wild-Type and LDLR+/- Rhesus Macaques.

scientific article published on March 2017

Nonclinical Pharmacology/Toxicology Study of AAV8.TBG.mLDLR and AAV8.TBG.hLDLR in a Mouse Model of Homozygous Familial Hypercholesterolemia

scientific article published on March 2017

Nonstatin Low-Density Lipoprotein-Lowering Therapy and Cardiovascular Risk Reduction-Statement From ATVB Council

scientific article

Normal production rate of apolipoprotein B in LDL receptor-deficient mice

scientific article

Novel ENU-induced point mutation in scavenger receptor class B, member 1, results in liver specific loss of SCARB1 protein

scientific article

Novel congenital disorder of O-linked glycosylation caused by GALNT2 loss of function

scientific article published on 15 April 2020

Novel in vivo method for measuring cholesterol mass flux in peripheral macrophages.

scientific article

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article

Nuclear Receptors and microRNA-144 Coordinately Regulate Cholesterol Efflux

scientific article published on June 7, 2013

On-Statin Cholesteryl Ester Transfer Protein Mass and Risk of Recurrent Coronary Events (from the Pravastatin or Atorvastatin Evaluation and Infection Therapy–Thrombolysis in Myocardial Infarction 22 [PROVE IT-TIMI 22] Study)

scientific article published on August 15, 2010

On-Statin Resistin, Leptin, and Risk of Recurrent Coronary Events After Hospitalization for an Acute Coronary Syndrome (from the Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis in Myocardial Infarction 22 Study).

scientific article

Oral Apolipoprotein A-I Mimetic D-4F Lowers HDL-Inflammatory Index in High-Risk Patients: A First-in-Human Multiple-Dose, Randomized Controlled Trial

scientific article published on 9 August 2017

Overexpression and deletion of phospholipid transfer protein reduce HDL mass and cholesterol efflux capacity but not macrophage reverse cholesterol transport

scientific article published on 30 January 2017

Overexpression of apolipoprotein A-I promotes reverse transport of cholesterol from macrophages to feces in vivo

scientific article published on 4 August 2003

Overexpression of apolipoprotein F reduces HDL cholesterol levels in vivo.

scientific article

Overexpression of apolipoprotein O does not impact on plasma HDL levels or functionality in human apolipoprotein A-I transgenic mice

scientific article published on 03 February 2011

PCSK9 loss of function is protective against extra-coronary atherosclerotic cardiovascular disease in a large multi-ethnic cohort

scientific article published on 09 November 2020

PPARγ activation redirects macrophage cholesterol from fecal excretion to adipose tissue uptake in mice via SR-BI.

scientific article published in February 2011

Pathogenic LMNA variants disrupt cardiac lamina-chromatin interactions and de-repress alternative fate genes

scientific article published on 01 February 2021

Pathway-Wide Association Study Implicates Multiple Sterol Transport and Metabolism Genes in HDL Cholesterol Regulation.

scientific article published on 5 July 2011

Pathways by which reconstituted high-density lipoprotein mobilizes free cholesterol from whole body and from macrophages

scientific article

Perhexiline activates KLF14 and reduces atherosclerosis by modulating ApoA-I production

scientific article

Permanent alteration of PCSK9 with in vivo CRISPR-Cas9 genome editing

scientific article

Peroxisome Proliferator-Activated Receptor-α Activation Promotes Macrophage Reverse Cholesterol Transport Through a Liver X Receptor–Dependent Pathway

scientific article published on March 24, 2011

Persistent liver expression of murine apoA-l using vectors based on adeno-associated viral vectors serotypes 5 and 1.

scientific article

Pharmacologic suppression of hepatic ATP-binding cassette transporter 1 activity in mice reduces high-density lipoprotein cholesterol levels but promotes reverse cholesterol transport

scientific article published on 22 August 2011

Pharmacological activation of liver X receptors promotes reverse cholesterol transport in vivo

scientific article published on 19 December 2005

Phenome-wide association analysis suggests the APOL1 linked disease spectrum primarily drives kidney-specific pathways

scientific article published on 17 February 2020

Phenotypic Characterization of Genetically Lowered Human Lipoprotein(a) Levels

scientific article published on December 2016

Phenotypic extremes in rare variant study designs

scientific article published on 9 September 2015

Phospholipidation of HDL--how much is too much?

scientific article published on 15 November 2010

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

scientific article (publication date: 11 August 2012)

Plasma Leptin Levels Are Associated with Coronary Atherosclerosis in Type 2 Diabetes

scientific article published on 01 August 2004

Plasma apolipoprotein C-III levels, triglycerides, and coronary artery calcification in type 2 diabetics

scientific article

Plasma cytokines, metabolic syndrome, and atherosclerosis in humans

scientific article published in January 2007

Polygenic Risk Score Identifies Subgroup With Higher Burden of Atherosclerosis and Greater Relative Benefit From Statin Therapy in the Primary Prevention Setting

scientific article published on 21 February 2017

Polygenic Risk Scores and Coronary Artery Disease: Ready for Prime Time?

scientific article published on 24 February 2020

Polygenic Risk of Psychiatric Disorders Exhibits Cross-trait Associations in Electronic Health Record Data From European Ancestry Individuals

scientific article published on 06 July 2020

Polygenic determinants in extremes of high-density lipoprotein cholesterol

scientific article published on 4 September 2017

Polyphenols and cholesterol efflux: is coffee the next red wine?

scientific article published on March 2010

Posttranscriptional control of the expression and function of diacylglycerol acyltransferase-1 in mouse adipocytes.

scientific article published on 28 October 2002

Potent and selective PPAR-alpha agonist LY518674 upregulates both ApoA-I production and catabolism in human subjects with the metabolic syndrome

scientific article

Potent peroxisome proliferator-activated receptor-α agonist treatment increases cholesterol efflux capacity in humans with the metabolic syndrome

scientific article

Practical immunoaffinity-enrichment LC-MS for measuring protein kinetics of low-abundance proteins

scientific article published on 21 April 2014

Primary deficiency of microsomal triglyceride transfer protein in human abetalipoproteinemia is associated with loss of CD1 function

scientific article

Proprotein convertases [corrected] are responsible for proteolysis and inactivation of endothelial lipase

scientific journal article

Prospective CYP2C19 Genotyping to Guide Antiplatelet Therapy Following Percutaneous Coronary Intervention: A Pragmatic Randomized Clinical Trial

scientific article published on 12 January 2020

Prospective study of insulin-like growth factor-I, insulin-like growth factor-binding protein 3, genetic variants in the IGF1 and IGFBP3 genes and risk of coronary artery disease.

scientific article

Protein-Truncating Variants at the Cholesteryl Ester Transfer Protein Gene and Risk for Coronary Heart Disease

scientific article published on 15 May 2017

Quantification of abdominal fat from computed tomography using deep learning and its association with electronic health records in an academic biobank

scientific article published on 01 June 2021

Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease

scientific journal article

Rationale and design of the familial hypercholesterolemia foundation CAscade SCreening for Awareness and DEtection of Familial Hypercholesterolemia registry

scientific article

Reconstituted high-density lipoprotein can elevate plasma alanine aminotransferase by transient depletion of hepatic cholesterol: role of the phospholipid component

scientific article published on 9 December 2015

Red yeast rice for dyslipidemia in statin-intolerant patients: a randomized trial

scientific article

Reduced Apolipoprotein M and Adverse Outcomes Across the Spectrum of Human Heart Failure

scientific article published on 02 April 2020

Reduced efficacy of rosuvastatin by St. John's Wort

scientific article published in February 2009

Reducing the burden of disease and death from familial hypercholesterolemia: a call to action

scientific article published on 16 September 2014

Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution

article

Relationship of estimated GFR and coronary artery calcification in the CRIC (Chronic Renal Insufficiency Cohort) Study

scientific article

Residual macrovascular risk in 2013: what have we learned?

scientific article

Resistin gene variation is associated with systemic inflammation but not plasma adipokine levels, metabolic syndrome or coronary atherosclerosis in nondiabetic Caucasians

scientific article

Resistin is an inflammatory marker of atherosclerosis in humans

scientific article published on 14 February 2005

Robust passive and active efflux of cellular cholesterol to a designer functional mimic of high density lipoprotein

scientific article published on 4 February 2015

Role of N-linked glycosylation in the secretion and activity of endothelial lipase

scientific article published on September 2004

SARS-CoV-2 Seroprevalence Among Parturient Women

scientific article published on 10 July 2020

SARS-CoV-2 seroprevalence among parturient women in Philadelphia

scientific article published on 01 July 2020

SLCO1B1 and Statin Therapy

scientific article published on 01 September 2018

Safety and efficacy of LY3015014, a monoclonal antibody to proprotein convertase subtilisin/kexin type 9 (PCSK9): a randomized, placebo-controlled Phase 2 study

scientific article published on 12 January 2016

Safety, pharmacokinetics, and pharmacodynamics of oral apoA-I mimetic peptide D-4F in high-risk cardiovascular patients

scientific article published on 6 March 2008

Seasonal human coronavirus antibodies are boosted upon SARS-CoV-2 infection but not associated with protection

scientific article published on 10 November 2020

Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study

scientific article published on 31 July 2013

Self-Organizing Human Induced Pluripotent Stem Cell Hepatocyte 3D Organoids Inform the Biology of the Pleiotropic TRIB1 Gene

scientific article published on 08 July 2020

Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction

scientific article

Serum Fractalkine (CX3CL1) and Cardiovascular Outcomes and Diabetes: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study

scientific article published on 17 March 2015

Short-term overexpression of DGAT1 or DGAT2 increases hepatic triglyceride but not VLDL triglyceride or apoB production

scientific article published on 30 July 2006

Short-term treatment with high-dose atorvastatin reduces LDL cholesterol but shows no anti-inflammatory effects in normolipidemic subjects with normal CRP levels

scientific article

Soluble FMS-Like Tyrosine Kinase-1 Is a Circulating Biomarker Associated With Calcific Aortic Stenosis

scientific article published on 01 March 2019

Sortilin and lipoprotein metabolism: making sense out of complexity

scientific article

Sortilin as a Regulator of Lipoprotein Metabolism

scientific article published on June 1, 2012

Sortilin mediates vascular calcification via its recruitment into extracellular vesicles

scientific article

Stable liver-specific expression of human IDOL in humanized mice raises plasma cholesterol

scientific article published on 19 January 2016

Statins and cognitive function: a systematic review

scientific article

Strong synaptic transmission impact by copy number variations in schizophrenia

scientific article

Structural and functional consequences of the Milano mutation (R173C) in human apolipoprotein A-I.

scientific article published on 24 March 2009

Structural basis of endothelial lipase tropism for HDL.

scientific article published on 28 September 2004

Structure-function properties of the apoE-dependent COX-2 pathway in vascular smooth muscle cells

scientific article published on 25 May 2007

Substrate specificity of lipoprotein lipase and endothelial lipase: studies of lid chimeras

scientific article published on 8 May 2006

Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease

scientific article published on February 2017

Systematic cell-based phenotyping of missense alleles empowers rare variant association studies: a case for LDLR and myocardial infarction

scientific article published on 3 February 2015

Systematically Sifting Big Data to Identify Novel Causal Genes for Human Traits

scientific article published on 01 April 2020

TTC39B deficiency stabilizes LXR reducing both atherosclerosis and steatohepatitis.

scientific article

Targeted exonic sequencing of GWAS loci in the high extremes of the plasma lipids distribution

scientific article

Targeting ApoC-III to Reduce Coronary Disease Risk

scientific article

Targeting the Coronavirus Nucleocapsid Protein through GSK-3 Inhibition

scientific article

Text mining applied to electronic cardiovascular procedure reports to identify patients with trileaflet aortic stenosis and coronary artery disease

scientific article

The Role of Emerging Biomarkers in Unraveling the Complex Biology Underlying Associations between HDL Cholesterol and Cardiovascular Diseases

scientific article published on 4 November 2016

The T111I variant in the endothelial lipase gene and risk of coronary heart disease in three independent populations

scientific article published on 02 May 2009

The ability to promote efflux via ABCA1 determines the capacity of serum specimens with similar high-density lipoprotein cholesterol to remove cholesterol from macrophages

scientific article

The addition of niacin to statin therapy improves high-density lipoprotein cholesterol levels but not metrics of functionality

scientific article published on 7 August 2013

The complexity of ABO in coronary heart disease – Authors' reply

scientific article published in The Lancet

The effect of PPAR-alpha agonism on apolipoprotein metabolism in humans

scientific article published on 14 December 2009

The effects of apolipoprotein F deficiency on high density lipoprotein cholesterol metabolism in mice

scientific journal article

The effects of statin therapy on plasma markers of inflammation in patients without vascular disease.

scientific article

The evolution and refinement of traditional risk factors for cardiovascular disease

scientific article published in May 2012

The frequency of the cholesteryl ester transfer protein-TaqI B2 allele is lower in African Americans than in Caucasians

scientific article published on 01 July 2002

The influence of pravastatin and atorvastatin on markers of oxidative stress in hypercholesterolemic humans

scientific article published on April 2008

The metabolic syndrome: more than the sum of its parts?

scientific article published on September 2003

The not-so-simple HDL story: Is it time to revise the HDL cholesterol hypothesis?

scientific article published on 01 September 2012

The novel atherosclerosis locus at 10q11 regulates plasma CXCL12 levels

scientific article

The role of endothelial lipase in high-density lipoprotein metabolism

scientific article published in July 2004

The role of high density lipoproteins in thrombosis

scientific article

The role of resting myocardial blood flow and myocardial blood flow reserve as a predictor of major adverse cardiovascular outcomes

scientific article published on 13 February 2020

The role of reverse cholesterol transport in animals and humans and relationship to atherosclerosis

scientific article published on 8 December 2008

The roles of different pathways in the release of cholesterol from macrophages

scientific article published on 29 August 2007

The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm

article

The triglyceride-high-density lipoprotein axis: an important target of therapy?

scientific article published in August 2004

Therapeutic Targets of Triglyceride Metabolism as Informed by Human Genetics

scientific article published on 14 March 2016

Tissue-specific expression pattern of human endothelial lipase in transgenic mice

scientific article published on 24 February 2005

Tissue-specific liver X receptor activation promotes macrophage reverse cholesterol transport in vivo

scientific article

Tolerability of red yeast rice (2,400 mg twice daily) versus pravastatin (20 mg twice daily) in patients with previous statin intolerance.

scientific article published on 26 November 2009

Transcriptome-Wide Analysis Reveals Modulation of Human Macrophage Inflammatory Phenotype Through Alternative Splicing

scientific article

Translational studies of lipoprotein-associated phospholipase A₂ in inflammation and atherosclerosis

scientific article published on February 2012

Treatment Gaps in Adults With Heterozygous Familial Hypercholesterolemia in the United States: Data From the CASCADE-FH Registry

scientific article

Treatment of patients with cardiovascular disease with L-4F, an apo-A1 mimetic, did not improve select biomarkers of HDL function.

scientific article

Trials and Tribulations of CETP Inhibitors

scientific article

Trib1 is a lipid- and myocardial infarction-associated gene that regulates hepatic lipogenesis and VLDL production in mice

scientific article

Tribbles-1 regulates hepatic lipogenesis through posttranscriptional regulation of C/EBPα

scientific article

Triglyceride-rich lipoproteins and coronary artery disease risk: new insights from human genetics

scientific article published on 08 January 2015

Two variants on chromosome 17 confer prostate cancer risk and the one in TCF2 protects against type 2 diabetes

article

US physician practices for diagnosing familial hypercholesterolemia: data from the CASCADE-FH registry

scientific article

Underdiagnosis and undertreatment of cardiovascular risk factors in patients with moderate to severe psoriasis.

scientific article published on 22 October 2011

Update on the Role of Endothelial Lipase in High-Density Lipoprotein Metabolism, Reverse Cholesterol Transport, and Atherosclerosis

scientific article published on October 15, 2010

Upregulation of macrophage endothelial lipase by toll-like receptors 4 and 3 modulates macrophage interleukin-10 and -12 production

scientific article

Usefulness of insulin resistance estimation and the metabolic syndrome in predicting coronary atherosclerosis in type 2 diabetes mellitus

scientific article

VLDL Hydrolysis by Hepatic Lipase Regulates PPARδ Transcriptional Responses

scientific article published on July 5, 2011

Val64Ile polymorphism in the C-C chemokine receptor 2 is associated with reduced coronary artery calcification

scientific article published in November 2002

Validating a non-invasive, ALT-based non-alcoholic fatty liver phenotype in the million veteran program

scientific article published on 25 August 2020

Variant ASGR1 Associated with a Reduced Risk of Coronary Artery Disease

scientific article

Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes

scientific article (publication date: March 2006)

Vasomotor symptoms and lipids/lipoprotein subclass metrics in midlife women: Does level of endogenous estradiol matter? The SWAN HDL Ancillary Study

scientific article published on 08 July 2020

Web of Science’s Citation Median Metrics Overcome the Major Constraints of the Journal Impact Factor

scientific article published in 2022

When HDL gets fat...

scientific article published on July 2008

Whole-genome sequencing reveals host factors underlying critical COVID-19

scientific article published in July 2022

Wild-type ApoA-I and the Milano variant have similar abilities to stimulate cellular lipid mobilization and efflux

scientific article published on 05 July 2007

Zinc transporter Slc39a8 is essential for cardiac ventricular compaction

scientific article published on 16 January 2018