List of works by Daniel A Kirschner

?1-Antichymotrypsin Binding to Alzheimer A? Peptides Is Sequence Specific and Induces Fibril Disaggregation In Vitro

scientific article published on 01 July 1993

A bacteriophage capsid protein provides a general amyloid interaction motif (GAIM) that binds and remodels misfolded protein assemblies.

scientific article

A single intravenous rAAV injection as late as P20 achieves efficacious and sustained CNS Gene therapy in Canavan mice.

scientific article

A survey of neurological mutant mice. I. Lipid composition of myelinated tissue in known myelin mutants

scientific article published on 01 January 1988

A survey of neurological mutant mice. II. Lipid composition of myelinated tissue in possible myelin mutants.

scientific article published in January 1988

Alzheimer's beta-amyloid: insights into fibril formation and structure from Congo red binding.

scientific article

Amyloid-like properties of a synthetic peptide corresponding to the carboxy terminus of beta-amyloid protein precursor.

scientific article published in January 1992

Analysis of x-ray diffraction patterns from amyloid of biopsied vitreous humor and kidney of transthyretin (TTR) Met30 familial amyloidotic polyneuropathy (FAP) patients: axially arrayed TTR monomers constitute the protofilament

article

Assemblies of Alzheimer's peptides A beta 25-35 and A beta 31-35: reverse-turn conformation and side-chain interactions revealed by X-ray diffraction.

scientific article

Claudin-11 Tight Junctions in Myelin Are a Barrier to Diffusion and Lack Strong Adhesive Properties.

scientific article

Collagen type II differs from type I in native molecular packing

scientific article published on 01 December 1980

Compact myelin exists in the absence of basic protein in the shiverer mutant mouse

scientific article published in Nature

Comparative diffraction studies on myelin membranes.

scientific article

Conformation and fibrillogenesis of Alzheimer A beta peptides with selected substitution of charged residues.

scientific article published on November 1994

Constitutively active Akt induces enhanced myelination in the CNS

scientific article

Cotinine reduces amyloid-β aggregation and improves memory in Alzheimer's disease mice

scientific article published in January 2011

Curcumin derivatives promote Schwann cell differentiation and improve neuropathy in R98C CMT1B mice.

scientific article published in December 2012

Cytologic and molecular analysis of 46,XXq- cells to identify a DNA segment that might serve as a probe for a putative human X chromosome inactivation center.

scientific article published on January 1983

Cytoplasmic domain of human myelin protein zero likely folded as beta-structure in compact myelin.

scientific article published on December 2006

Designing recombinant spider silk proteins to control assembly

article

Different Intracellular Pathomechanisms Produce Diverse Myelin Protein Zero Neuropathies in Transgenic Mice

scientific article published on 01 February 2006

Differential effects of Phe19 and Phe20 on fibril formation by amyloidogenic peptide A beta 16-22 (Ac-KLVFFAE-NH2).

scientific article published in August 2010

Differential expression of gangliosides on the surfaces of myelinated nerve fibers

scientific article published on 01 January 1984

Dynamics of myelin membrane contacts

scientific article published on 01 January 1980

Effects of ZnCl2 on membrane interactions in myelin of normal and shiverer mice

scientific article published on 01 October 1984

Effects of rumpshaker mutation on CNS myelin composition and structure

scientific article published on 01 January 1996

Effects of sulfate ions on Alzheimer beta/A4 peptide assemblies: implications for amyloid fibril-proteoglycan interactions

scientific article published on October 1, 1992

Evolution of a neuroprotective function of central nervous system myelin

scientific article

Evolution of myelin ultrastructure and the major structural myelin proteins.

scientific article

Fiber diffraction as a screen for amyloid inhibitors

scientific article published on June 2008

Fibril formation by primate, rodent, and Dutch-hemorrhagic analogues of Alzheimer amyloid beta-protein

scientific article published on November 10, 1992

Filaments of the Ure2p prion protein have a cross-beta core structure.

scientific article published on May 2005

Folding and function of the myelin proteins from primary sequence data ⬇️

scientific article published on January 1, 1991

Formation of amyloid fibrils in vitro by human gammaD-crystallin and its isolated domains.

scientific article

Ganglioside localization on myelinated nerve fibres by cholera toxin binding

scientific article published on 01 December 1983

Generation of DM-20 splice site in myelin proteolipid protein gene: a hypothesis based on analysis of the amphibian protein

scientific article published on July 1, 1991

Histidine residues underlie Congo red binding to A beta analogs.

scientific article

Immunolocalization of 17 and 21.5 kDa MBP isoforms in compact myelin and radial component

scientific article published on 01 January 1996

Implications of the sequence similarities between tau and myelin basic protein

scientific article published on 01 September 1995

In vitro amyloid fibril formation by synthetic peptides corresponding to the amino terminus of apoSAA isoforms from amyloid-susceptible and amyloid-resistant mice

scientific article published on 01 December 1998

Inherited demyelinating peripheral neuropathies: relating myelin packing abnormalities to P0 molecular defects

scientific article published on 01 November 1996

Internodal myelination during development quantitated using X-ray diffraction.

scientific article

Is myelin basic protein crystallizable?

scientific article

Jimpy 4J: a new X-linked mouse mutation producing severe CNS hypomyelination.

scientific article published in January 1995

Kinetic theory of fibrillogenesis of amyloid β-protein ⬇️

scientific article published on July 22, 1997

Lack of collagen XV impairs peripheral nerve maturation and, when combined with laminin-411 deficiency, leads to basement membrane abnormalities and sensorimotor dysfunction

scientific article published on 01 October 2010

Laminin inhibition of beta-amyloid protein (Abeta) fibrillogenesis and identification of an Abeta binding site localized to the globular domain repeats on the laminin a chain

scientific article published on November 2000

Membrane adhesion in peripheral myelin: good and bad wraps with protein P0.

scientific article

Membrane interactions are altered in myelin isolated from central and peripheral nervous system tissues

scientific article published on 01 July 1988

Membrane interactions in nerve myelin. I. Determination of surface charge from effects of pH and ionic strength on period.

scientific article

Membrane interactions in nerve myelin: II. Determination of surface charge from biochemical data

scientific article

Membrane structure in isolated and intact myelins

scientific article

Membrane topology of PLP in CNS myelin: evaluation of models

scientific article published on 01 August 1994

Mice deficient for the myelin-associated glycoprotein show subtle abnormalities in myelin.

scientific article

Molecular Characterization of Myelin Protein Zero in Xenopus laevis Peripheral Nerve: Equilibrium between Non-covalently Associated Dimer and Monomer

scientific article published on December 2007

Molecular determinants of amyloid deposition in Alzheimer's disease: conformational studies of synthetic beta-protein fragments.

scientific article published in March 1990

Molecular organization of amyloid protofilament-like assembly of betabellin 15D: helical array of beta-sandwiches

scientific article

Morphological evidence of alteration in myelinstructure with maturation

scientific article (publication date: 3 September 1976)

Multilamellar packing of myelin modeled by lipid-bound MBP

scientific article published on 01 February 2000

Mutations in demyelinating peripheral neuropathies support molecular model of myelin P0-glycoprotein extracellular domain

scientific article published on 01 September 1994

Myelin P0-glycoprotein: predicted structure and interactions of extracellular domain

scientific article published on 01 December 1993

Myelin abnormalities in the optic and sciatic nerves in mice with GM1-gangliosidosis

scientific article

Myelin labeled with mercuric chloride. Asymmetric localization of phosphatidylethanolamine plasmalogen

scientific article published on 01 June 1982

Myelin membrane from adrenoleukodystrophy brain white matter--biochemical properties.

scientific article published in August 1983

Myelin membrane structure and composition correlated: a phylogenetic study

scientific article published on 01 November 1989

Myelin organization in the nodal, paranodal, and juxtaparanodal regions revealed by scanning x-ray microdiffraction

scientific article

Myelin protein zero exists as dimers and tetramers in native membranes of Xenopus laevis peripheral nerve

scientific article published in March 2002

Myelin structure and composition in zebrafish

scientific article published on 02 September 2006

Myelin structure and composition of myelinated tissue in the African lungfish

scientific article published on 01 May 2008

Myelin structure in unfixed, single nerve fibers: Scanning X-ray microdiffraction with a beam size of 200nm

scientific article published on 8 July 2017

Myelin structure is unaltered in chemotherapy-induced peripheral neuropathy

scientific article published on 4 November 2011

Myelin structure transformed by dimethylsulfoxide ⬇️

scientific article published on September 1, 1975

Myelination in the developing human brain: biochemical correlates

scientific article published on 01 August 1994

Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

scientific article

Neutron diffraction studies of nerve myelin

scientific article published on May 1, 1976

Neutron scattering from myelin revisited: bilayer asymmetry and water-exchange kinetics.

scientific article published on 22 November 2014

New X-ray spacings from central myelinated tissue

scientific article published in December 1984

Orientation of proteolipid protein in myelin: comparison of models with X-ray diffraction measurements

scientific article published on 01 January 1989

P0 (protein zero) mutation S34C underlies instability of internodal myelin in S63C mice.

scientific article

Peripheral myelin of Xenopus laevis: role of electrostatic and hydrophobic interactions in membrane compaction

scientific article

Peripheral nervous system manifestations in a Sandhoff disease mouse model: nerve conduction, myelin structure, lipid analysis.

scientific article

Peripheral nervous system plasmalogens regulate Schwann cell differentiation and myelination

scientific article

Phylogenetically conserved amino acids of MBP and P0 from amphibian myelin

scientific article published on January 1, 1992

Plasmalogen phospholipids protect internodal myelin from oxidative damage

scientific article published on 21 March 2015

Poly-(L-alanine) expansions form core beta-sheets that nucleate amyloid assembly.

scientific article

Polyglutamine homopolymers having 8-45 residues form slablike beta-crystallite assemblies

scientific article published on 01 November 2005

Polypeptide chain folding in the hydrophobic core of hamster scrapie prion: analysis by X-ray diffraction

article

Processing for electron microscopy alters membrane structure and packing in myelin

scientific article published on 01 November 1980

Protein and lipid composition of radial component-enriched CNS myelin

scientific article published on 01 March 1994

Proton magnetic resonance in myelin deficient brains of mutant mice.

scientific article

Quaking*jimpy double mutant mice: additional evidence for independence of primary deficits in jimpy

scientific article published in April 1990

Quantitative differences between homozygous 'USA' and 'Swiss' mld mutant mice

scientific article published in January 1991

Radial component of CNS myelin: junctional subunit structure and supramolecular assembly

scientific article published on 01 April 1990

Rapid assessment of internodal myelin integrity in central nervous system tissue.

scientific article

Restricted hypotonic swelling of peripheral nerve myelin in streptozocin-induced diabetic rats

scientific article published on 01 June 1994

SCAP is required for timely and proper myelin membrane synthesis

scientific article

Shiverer and normal peripheral myelin compared: basic protein localization, membrane interactions, and lipid composition

scientific article published in December 1985

Shiverer jimpy double mutant mice. II. Morphological evidence supports reciprocal intergenic suppression

scientific article published in May 1986

Shiverer jimpy double mutant mice. III. Comparison of shimld*jpmsd and shi*jp phenotypes demonstrates dissimilar interactions of allelic mutations.

scientific article

Shiverer jimpy double mutant mice. V. Correlation of genotype and myelin proteins

scientific article published in January 1991

Spinal cord myelin is vulnerable to decompression

scientific article

Structural analysis of Alzheimer's beta(1-40) amyloid: protofilament assembly of tubular fibrils.

scientific article

Structural changes in a hydrophobic domain of the prion protein induced by hydration and by ala-->Val and pro-->Leu substitutions

scientific article published on 01 July 2000

Structural properties of Gerstmann-Straussler-Scheinker disease amyloid protein.

scientific article published on 11 September 2003

Structural states of myelin observed by x-ray diffraction and freeze-fracture electron microscopy ⬇️

scientific article published on July 1, 1979

Structure and stability of internodal myelin in mouse models of hereditary neuropathy.

scientific article published in November 2005

Structure of beta-crystallite assemblies formed by Alzheimer beta-amyloid protein analogues: analysis by x-ray diffraction.

scientific article

Structure of core domain of fibril-forming PHF/Tau fragments.

scientific article

Structure of myelin lipid bilayers

scientific article published on 01 February 1982

Tetrameric assembly of full-sequence protein zero myelin glycoprotein by synchrotron x-ray scattering

scientific article

The interaction of mercurials with myelin: comparison of in vitro and in vivo effects

scientific article published on 01 January 1985

Thioridazine induces lipid peroxidation in myelin of rat brain

scientific article published in February 1993

Triethyl tin-induced myelin oedema: an intermediate swelling state detected by X-ray diffraction

scientific article published on 01 August 1982

Twist and sheet: variations on the theme of amyloid

scientific article published on 01 June 2000

Visualization of nonstructural changes in early white matter development on diffusion-weighted MR images: evidence supporting premyelination anisotropy.

scientific article

Water diffusion, T(2), and compartmentation in frog sciatic nerve

scientific article

X-Ray fiber and powder diffraction of PrP prion peptides.

scientific article published on January 2006

X-ray diffraction analysis of myelin lipid/proteolipid protein multilayers

scientific article published on 01 October 1989

X-ray diffraction analysis of tendon collagen at ambient and cryogenic temperatures: role of hydration

scientific article published on 01 February 1997

X-ray diffraction study of myelin structure in immature and mutant mice

scientific article published in September 1976

X-ray diffraction study of the kinetics of myelin lattice swelling. Effect of divalent cations

scientific article

pH-dependent structural transitions of Alzheimer amyloid peptides

scientific article

rAAV Gene Therapy in a Canavan's Disease Mouse Model Reveals Immune Impairments and an Extended Pathology Beyond the Central Nervous System.

scientific article published on 04 April 2016

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